Open Access e-Journal Cardiometry - No.15 November 2019

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STR. They concluded that higher NLR at the time ofadmission in patients with acute myocardial infarctionundergoing primary coronary intervention iscorrelated with coronary no reflow phenomenon andpoor long term prognosis. The results of their studymatches our results as well (10).ConclusionIn our study we evaluated the relationship betweenneutrophil count, lymphocyte count, NLR, RDW,PDW and RPR with STR. There was only a significantcorrelation between NLR and STR. NLR was significantlylower in patients with STR>70%.On the other hand, there was a significant relationshipobserved between all mentioned indexed exceptRDW and PDW with 2 month complications.It can be concluded that it is possible to use NLRand RPR to predict STR and short term complicationsin patients with acute myocardial infarction undergoingprimary coronary intervention.Based on our results, it seems that applying mentionedcheap, fast and accessible markers along withother prognostic markers and clinical conditions indaily practice, can be helpful in prognosis predictionand choosing the best treatment strategy (using anti-inflammatoryagents such as Canakinumab) in futureto prevent recurrence of acute coronary infarction(56,63).Statement on ethical issuesResearch involving people and/or animals is in fullcompliance with current national and internationalethical standards.Conflict of interestNone declared.Author contributionsThe authors read the ICMJE criteria for authorshipand approved the final manuscript.References1. Buchanan GL, Chieffo A, Colombo A. Is there still asurvival advantage to bypass surgery over percutaneousintervention in the modern era? Progress in cardiovasculardiseases. 2015;58(3):335-41.2. Schwartz BG, Kloner RA. Coronary no reflow.Journal of molecular and cellular cardiology. 2012;52(4):873-82.3. Oncel RC, Ucar M, Karakas MS, Akdemir B,Yanikoglu A, Gulcan AR, et al. Relation of neutrophil-to-lymphocyteratio with GRACE risk score toin-hospital cardiac events in patients with ST-segmentelevated myocardial infarction. Clinical and AppliedThrombosis/Hemostasis. 2015;21(4):383-8.4. Akpek M, Kaya MG, Lam YY, Sahin O, Elcik D, CelikT, et al. Relation of neutrophil/lymphocyte ratioto coronary flow to in-hospital major adverse cardiacevents in patients with ST-elevated myocardial infarctionundergoing primary coronary intervention. TheAmerican journal of cardiology. 2012;110(5):621-7.5. Cho KH, Jeong MH, Ahmed K, Hachinohe D, ChoiHS, Chang SY, et al. Value of early risk stratification usinghemoglobin level and neutrophil-to-lymphocyte ratio inpatients with ST-elevation myocardial infarction undergoingprimary percutaneous coronary intervention. TheAmerican journal of cardiology. 2011;107(6):849-56.6. Park JJ, Jang H-J, Oh I-Y, Yoon C-H, Suh J-W, ChoY-S, et al. Prognostic value of neutrophil to lymphocyteratio in patients presenting with ST-elevationmyocardial infarction undergoing primary percutaneouscoronary intervention. The American journalof cardiology. 2013;111(5):636-42.7. Pellizzon GG, Dixon SR, Stone GW, Cox DA. Relationof admission white blood cell count to longtermoutcomes after primary coronary angioplasty foracute myocardial infarction (The Stent PAMI Trial).The American journal of cardiology. 2003;91(6):729-.8. Furman MI, Gore JM, Anderson FA, Budaj A,Goodman SG, Avezum Á, et al. Elevated leukocytecount and adverse hospital events in patients withacute coronary syndromes: findings from the GlobalRegistry of Acute Coronary Events (GRACE). Americanheart journal. 2004;147(1):42-8.9. Uğur M, Ayhan E, Bozbay M, Çiçek G, Ergelen M,Işık T, et al. The independent association of plateletcritwith long-term outcomes in patients undergoingprimary percutaneous coronary intervention. Journalof critical care. 2014;29(6):978-81.10. Sen N, Afsar B, Ozcan F, Buyukkaya E, Isleyen A,Akcay AB, et al. The neutrophil to lymphocyte ratiowas associated with impaired myocardial perfusion andlong term adverse outcome in patients with ST-elevatedmyocardial infarction undergoing primary coronaryintervention. Atherosclerosis. 2013;228(1):203-10.11. Varastehravan H, Naghedi A, Nough H, PourmirafzaliH. The relationship between severity of coronaryartery disease and mean platelet volume2019.54 | Cardiometry | Issue 15. November 2019
12. Sun X-p, Chen W-m, Sun Z-j, Ding X-s, GaoX-y, Liang S-w, et al. Impact of red blood cell distributionwidth on long-term mortality in patientswith ST-elevation myocardial infarction. Cardiology.2014;128(4):343-8.13. Sejersten M, Ripa RS, Maynard C, Wagner GS,Andersen HR, Grande P, et al. Usefulness of quantitativebaseline ST-segment elevation for predictingoutcomes after primary coronary angioplasty or fibrinolysis(results from the DANAMI-2 trial). TheAmerican journal of cardiology. 2006;97(5):611-6.14. de Lemos JA, Antman EM, Giugliano RP, McCabeCH, Murphy SA, Van de Werf F, et al. ST-segmentresolution and infarct-related artery patency and flowafter thrombolytic therapy. The American journal ofcardiology. 2000;85(3):299-304.15. Taefi A, Huang C-C, Kolli K, Ebrahimi S, Patel M.Red cell distribution width to platelet ratio, a usefulindicator of liver fibrosis in chronic hepatitis patients.Hepatology international. 2015;9(3):454-60.16. Yaylak B, Ede H, Baysal E, Altıntas B, Akyuz S,Sevuk U, et al. Neutrophil/lymphocyte ratio is associatedwith right ventricular dysfunction in patientswith acute inferior ST-segment elevation myocardialinfarction. Cardiology journal. 2016;23(1):100-6.17. Celık T, Balta S, Demır M, Yıldırım AO, KayaMG, Ozturk C, et al. Predictive value of admissionred cell distribution width-platelet ratio for no-reflowphenomenon in acute ST segment elevationmyocardial infarction undergoing primary percutaneouscoronary intervention. Cardiology journal.2016;23(1):84-92.18. Gul U, Kayani A, Munir R, Hussain S. Neutrophillymphocyte ratio: APrognostic marker in acute ST elevationmyocardial infarction. J Coll Physicians SurgPak. 2017;27(1):4-7.19. Terakura M, Sugawara T, Hirota D, Sagawa T,Sakamoto T. Red cell and platelet distribution widthsin patients with angina pectoris and acute myocardialinfarction. Acute medicine & surgery. 2016;3(3):244-9.20. Yalcinkaya E, Yuksel UC, Celik M, Kabul HK, BarcinC, Gokoglan Y, et al. Relationship between neutrophil-to-lymphocyteratio and electrocardiographicischemia grade in STEMI. Arquivos brasileiros de cardiologia.2015;104(2):112-9.21. Soylu K, Yuksel S, Gulel O, Erbay AR, Meric M,Zengin H, et al. The relationship of coronary flow toneutrophil/lymphocyte ratio in patients undergoingprimary percutaneous coronary intervention. Journalof thoracic disease. 2013;5(3):258.22. Turkmen S, Dogdu O, Tekin K, Kucukdurmaz Z,Cagliyan C, Sarikaya S, et al. The relationship betweenneutrophil/lymphocyte ratio and the TIMI flow gradein patients with STEMI undergoing primary PCI. EurRev Med Pharmacol Sci. 2013;17(16):2185-9.23. Gazi E, Bayram B, Gazi S, Temiz A, Kirilmaz B,Altun B, et al. Prognostic value of the neutrophil–lymphocyteratio in patients with ST-elevated acute myocardialinfarction. Clinical and Applied Thrombosis/Hemostasis. 2015;21(2):155-9.Issue 15. November 2019 | Cardiometry | 55
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