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P06 IMPACT OF TECHNOLOGY<br />

An <strong>in</strong>stitutional experience <strong>of</strong><br />

new technology <strong>in</strong> radio<strong>the</strong>rapy<br />

P07 DETECTOR DENSITY<br />

Impacts on small-field<br />

dosimetric measurements<br />

P07 RANGE UNCERTAINTY<br />

Proton range uncerta<strong>in</strong>ty <strong>in</strong><br />

patient stopp<strong>in</strong>g power ratios<br />

SCOPE<br />

INSTITUTE OF PHYSICS AND ENGINEERING IN MEDICINE | www.ipem.ac.uk | Volume 21 Issue 3 | SEPTEMBER 2012<br />

A work <strong>of</strong><br />

fiction?<br />

Alice through <strong>the</strong><br />

archive cupboard<br />

Radiat<strong>in</strong>g<br />

enthusiasm<br />

IPEM at <strong>the</strong> 2012 Big<br />

Bang Science Fair<br />

Call for engagement<br />

Science <strong>and</strong> Parliament


DOSIMETRY<br />

SOLUTIONS<br />

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A WIDER PERSPECTIVE<br />

Recently, it was my<br />

privilege to attend <strong>the</strong><br />

World Congress on<br />

Medical <strong>Physics</strong> <strong>and</strong><br />

Biomedical <strong>Eng<strong>in</strong>eer<strong>in</strong>g</strong><br />

<strong>in</strong> Beij<strong>in</strong>g, Ch<strong>in</strong>a, which<br />

was held under <strong>the</strong> banner <strong>of</strong><br />

‘Promot<strong>in</strong>g Health through<br />

Technology’. Spread over 5 days <strong>and</strong><br />

with at least 17 parallel sessions, this<br />

was clearly <strong>the</strong> challenge that came<br />

through those elements that I was able<br />

to experience directly!<br />

This congress occurs every 3 years<br />

<strong>and</strong> is held under <strong>the</strong> auspices <strong>of</strong> <strong>the</strong><br />

International Union <strong>of</strong> Physical <strong>and</strong><br />

<strong>Eng<strong>in</strong>eer<strong>in</strong>g</strong> Sciences <strong>in</strong> Medic<strong>in</strong>e<br />

(IUPESM). It br<strong>in</strong>gs toge<strong>the</strong>r <strong>the</strong><br />

International Federation for Medical<br />

<strong>and</strong> Biological <strong>Eng<strong>in</strong>eer<strong>in</strong>g</strong> (IFMBE)<br />

<strong>and</strong> <strong>the</strong> International Organisation for<br />

Medical <strong>Physics</strong> (IOMP), <strong>and</strong> <strong>the</strong>se<br />

societies were fur<strong>the</strong>r supported by<br />

<strong>the</strong> World Health Organization<br />

(WHO) <strong>and</strong> <strong>the</strong> International Atomic<br />

Energy Agency (IAEA) as global<br />

organisations with specific objectives<br />

<strong>in</strong> health.<br />

The world congress can seem a<br />

little remote from <strong>the</strong> issues <strong>in</strong><br />

healthcare science <strong>in</strong> <strong>the</strong> UK, or even<br />

<strong>in</strong> Europe, especially as this was <strong>the</strong><br />

third time <strong>in</strong> 9 years that it has been<br />

held <strong>in</strong> Asia. Although this perhaps<br />

reflects <strong>the</strong> changes <strong>in</strong> <strong>the</strong> global<br />

economic l<strong>and</strong>scape, it soon became<br />

clear to me that it is important not to<br />

lose sight <strong>of</strong> <strong>the</strong> global health<br />

challenges <strong>and</strong> <strong>the</strong> role that we could<br />

<strong>and</strong> should fulfil both <strong>in</strong>dividually<br />

<strong>and</strong> as IPEM.<br />

INTERNATIONAL<br />

RELATIONSHIPS<br />

IFMBE is directly l<strong>in</strong>ked to <strong>the</strong> WHO<br />

<strong>and</strong> <strong>the</strong> United Nations as a nongovernmental<br />

organisation<br />

(NGO). It is a position to<br />

which IOMP aspires <strong>and</strong><br />

hopes to achieve with<strong>in</strong><br />

<strong>the</strong> next 3 years. This<br />

relationship provides a<br />

route to <strong>in</strong>fluence <strong>the</strong> delivery<br />

<strong>of</strong> healthcare worldwide through<br />

physics <strong>and</strong> eng<strong>in</strong>eer<strong>in</strong>g <strong>and</strong> is<br />

already recognised <strong>in</strong> a programme<br />

with<strong>in</strong> <strong>the</strong> WHO which is seek<strong>in</strong>g to<br />

promote <strong>the</strong> development <strong>of</strong><br />

appropriate medical devices for<br />

Peter Jarritt<br />

President<br />

▼<br />

Be<strong>in</strong>g part <strong>of</strong><br />

<strong>the</strong> global<br />

medical physics<br />

community.<br />

develop<strong>in</strong>g countries. This challenge<br />

was powerfully delivered <strong>in</strong> a<br />

plenary lecture given by Adriana<br />

Velazquez Berumen who is coord<strong>in</strong>ator<br />

<strong>of</strong> <strong>the</strong> Medical Devices Unit<br />

at <strong>the</strong> WHO <strong>in</strong> Geneva. The<br />

availability <strong>and</strong> access to appropriate<br />

medical products <strong>and</strong> technologies is<br />

one <strong>of</strong> <strong>the</strong> WHO strategic objectives<br />

for its member states. It is not difficult<br />

to underst<strong>and</strong> such an objective <strong>in</strong><br />

relation to <strong>the</strong> develop<strong>in</strong>g world, yet<br />

to me, <strong>the</strong> challenge was identical to<br />

that fac<strong>in</strong>g <strong>the</strong> developed world. The<br />

healthcare agenda <strong>in</strong> <strong>the</strong> UK is to<br />

develop <strong>in</strong>novative, affordable <strong>and</strong><br />

appropriate healthcare technology to<br />

address <strong>the</strong> health needs <strong>of</strong> <strong>the</strong><br />

population. The develop<strong>in</strong>g world<br />

needs simple, low-powered, low-cost,<br />

robust <strong>and</strong> accurate diagnostic tools<br />

to solve <strong>the</strong>ir issues. Does this sound<br />

familiar?<br />

The congress had many <strong>the</strong>mes,<br />

some less familiar than o<strong>the</strong>rs,<br />

<strong>in</strong>clud<strong>in</strong>g education <strong>and</strong> tra<strong>in</strong><strong>in</strong>g,<br />

radiation safety, safety <strong>of</strong> medical<br />

devices, developments <strong>in</strong> photon <strong>and</strong><br />

ion <strong>the</strong>rapy <strong>and</strong> x-ray CT, biochipenabled<br />

translational medic<strong>in</strong>e, signal<br />

process<strong>in</strong>g <strong>and</strong> bio-magnetism <strong>and</strong><br />

physiology modell<strong>in</strong>g. It is good to<br />

know that research <strong>and</strong> development<br />

is alive <strong>and</strong> well.<br />

IPEM INVOLVEMENT<br />

IPEM will re-engage with<br />

<strong>the</strong> worldwide<br />

physics <strong>and</strong><br />

eng<strong>in</strong>eer<strong>in</strong>g<br />

community<br />

through <strong>the</strong><br />

International<br />

Conference<br />

on Medical<br />

<strong>Physics</strong> to be<br />

held <strong>in</strong><br />

Brighton,<br />

1st–4th<br />

September<br />

2013. The<br />

programme will<br />

address <strong>the</strong><br />

<strong>in</strong>ternational agenda as well<br />

as showcase <strong>the</strong> latest scientific<br />

research. Our response to <strong>and</strong><br />

<strong>in</strong>volvement <strong>in</strong> <strong>the</strong>se wider<br />

agendas is important.<br />

IPEM is formally l<strong>in</strong>ked as a<br />

PRESIDENT’S LETTER | SCOPE<br />

National Member Organisation to<br />

<strong>the</strong> European Federation <strong>of</strong><br />

Medical <strong>Physics</strong> (EFOMP) <strong>and</strong> <strong>the</strong><br />

IOMP. IPEM is able to nom<strong>in</strong>ate<br />

<strong>and</strong> support <strong>in</strong>dividuals who are<br />

will<strong>in</strong>g to st<strong>and</strong> as <strong>of</strong>ficers <strong>in</strong> <strong>the</strong>se<br />

organisations. Individuals do not<br />

represent IPEM but st<strong>and</strong> to<br />

develop <strong>and</strong> support <strong>the</strong> aims <strong>and</strong><br />

objectives <strong>of</strong> <strong>the</strong>ir respective<br />

organisation. IPEM supports <strong>and</strong><br />

benefits from <strong>the</strong>se activities<br />

<strong>in</strong>clud<strong>in</strong>g <strong>the</strong> formal recognition<br />

<strong>of</strong> <strong>the</strong> medical physicist as a<br />

healthcare pr<strong>of</strong>essional, <strong>the</strong><br />

specification <strong>of</strong> European<br />

st<strong>and</strong>ards for <strong>the</strong> medical physics<br />

expert, <strong>and</strong> <strong>the</strong> harmonisation <strong>and</strong><br />

recognition <strong>of</strong> tra<strong>in</strong><strong>in</strong>g<br />

programmes.<br />

If you have a passion for<br />

physics <strong>and</strong> eng<strong>in</strong>eer<strong>in</strong>g <strong>in</strong><br />

healthcare, I would encourage you<br />

to consider if <strong>the</strong>re is a role you<br />

would be prepared to undertake to<br />

support <strong>the</strong>se wider agendas. This<br />

might be through direct<br />

<strong>in</strong>volvement <strong>in</strong> programmes <strong>in</strong><br />

develop<strong>in</strong>g countries or through<br />

an <strong>in</strong>ternational organisation. The<br />

websites <strong>of</strong> EFOMP<br />

(www.efomp.org) <strong>and</strong> IOMP<br />

(www.iomp.org) provide an<br />

<strong>in</strong>dication <strong>of</strong> <strong>the</strong>ir respective<br />

activities. The IPEM VP<br />

International, Dr Manivannan<br />

(a.mani@adn.ac.uk), can provide<br />

fur<strong>the</strong>r <strong>in</strong>formation <strong>and</strong> advice.<br />

In conclusion we should not<br />

lose sight <strong>of</strong> <strong>the</strong> immediate needs<br />

<strong>of</strong> <strong>the</strong> pr<strong>of</strong>ession <strong>in</strong> <strong>the</strong> UK <strong>and</strong><br />

<strong>the</strong> contribution it can <strong>and</strong> does<br />

make to <strong>the</strong> delivery <strong>of</strong> healthcare.<br />

I would refer you to <strong>the</strong> article<br />

from Andrew Miller MP <strong>in</strong> this<br />

edition <strong>of</strong> Scope. Parliament<br />

represents <strong>the</strong> voice <strong>of</strong> <strong>the</strong> people<br />

<strong>and</strong> we should equally heed his<br />

encouragement to lobby <strong>and</strong><br />

<strong>in</strong>form our MPs, whe<strong>the</strong>r <strong>in</strong><br />

devolved governments or<br />

Westm<strong>in</strong>ster, to ensure that our<br />

contribution is recognised <strong>and</strong><br />

supported appropriately. This is a<br />

role we can all undertake. If you<br />

feel you would like support <strong>the</strong>n I<br />

would encourage you to talk to<br />

Steve Keevil (President Elect) or<br />

Carl Rowbottom (VP External).<br />

SCOPE | SEPTEMBER 2012 | 03


SCOPE | CONTENTS<br />

THIS ISSUE<br />

09<br />

13<br />

17<br />

26<br />

36<br />

COVER FEATURE<br />

ENGAGEMENT CALL<br />

The l<strong>in</strong>ks between<br />

science <strong>and</strong><br />

Parliament, <strong>and</strong> a<br />

challenge for all<br />

members<br />

04 | SEPTEMBER 2012 | SCOPE<br />

13 ALICE THROUGH THE ARCHIVE CUPBOARD<br />

A short story about what medical physicists get up to <strong>in</strong> <strong>the</strong>ir spare time.<br />

Can you f<strong>in</strong>d yourself?<br />

17 RADIATING ENTHUSIASM: IPEM AT THE 2012 BIG BANG SCIENCE FAIR<br />

How do you expla<strong>in</strong> radioactivity to a 6-year-old? Celebrat<strong>in</strong>g science,<br />

technology, eng<strong>in</strong>eer<strong>in</strong>g <strong>and</strong> maths with <strong>the</strong> next generation<br />

18 THE LAUNCH OF IPEM OUTREACH STRATEGY<br />

Help<strong>in</strong>g members to communicate science <strong>and</strong> eng<strong>in</strong>eer<strong>in</strong>g to students to<br />

encourage <strong>the</strong>m to study <strong>the</strong> subjects fur<strong>the</strong>r<br />

TRAVEL AWARD<br />

19 AAPM–IPEM MEDICAL PHYSICS TRAVEL GRANT REPORT<br />

Jun Deng<br />

MEETING REPORTS<br />

23 BESPOKE SOFTWARE IN MEDICAL PHYSICS AND CLINICAL ENGINEERING<br />

Andrew Rob<strong>in</strong>son<br />

26 2012 ESTRO 31/WORLD CONGRESS OF BRACHYTHERAPY<br />

Ahamed Badusha Mohamed Yoosuf<br />

30 REPORT ON NPL CLINICAL TEMPERATURE MEASUREMENT MEETING<br />

Rosie Richards <strong>and</strong> Jason Britton<br />

HISTORICAL FEATURE<br />

46 A HISTORY OF MEDICAL PHYSICS<br />

Francis Duck<br />

REGULARS<br />

03 PRESIDENT’S LETTER A wider perspective<br />

05 EDITORIAL Farewell Marc<br />

06 NEWS Recent discoveries <strong>in</strong> radio<strong>the</strong>rapy research<br />

33 INTERNATIONAL NEWS International conferences <strong>in</strong> 2012 <strong>and</strong> 2013<br />

35 MEMBERS’ NEWS Accolades for current <strong>and</strong> retir<strong>in</strong>g members<br />

40 BOOK REVIEWS Medical physics <strong>and</strong> popular science textbooks<br />

© r.nagy / Shutterstock


Scope is <strong>the</strong> quarterly<br />

magaz<strong>in</strong>e <strong>of</strong> <strong>the</strong> <strong>Institute</strong><br />

<strong>of</strong> <strong>Physics</strong> <strong>and</strong> <strong>Eng<strong>in</strong>eer<strong>in</strong>g</strong><br />

<strong>in</strong> Medic<strong>in</strong>e<br />

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EDITOR-IN-CHIEF<br />

Gemma Whitelaw<br />

Radio<strong>the</strong>rapy <strong>Physics</strong>,<br />

Basement, New KGV<br />

Build<strong>in</strong>g,<br />

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ASSISTANT EDITOR<br />

Usman I. Lula<br />

Department <strong>of</strong><br />

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MEETING REPORTS<br />

EDITOR<br />

Angela Cotton<br />

Head <strong>of</strong> Non-Ionis<strong>in</strong>g<br />

Radiation Support,<br />

Medical <strong>Physics</strong> &<br />

Bioeng<strong>in</strong>eer<strong>in</strong>g,<br />

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Hospital, Southampton,<br />

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swest.nhs.uk<br />

NEWS EDITORS<br />

Usman I. Lula<br />

Department <strong>of</strong><br />

Radio<strong>the</strong>rapy, Poole<br />

Hospital, Longfleet Road,<br />

Poole, BH15 2JB<br />

E usman.lula@poole.nhs.uk<br />

<strong>and</strong><br />

Richard A. Amos<br />

Department <strong>of</strong> Radiation<br />

<strong>Physics</strong>, The University <strong>of</strong><br />

Texas M.D. Anderson<br />

Cancer Center,<br />

1840 Old Spanish<br />

Trail,Houston,<br />

Texas 77054, U.S.A.<br />

T + 1 713 563 6894<br />

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org<br />

BOOK REVIEW EDITOR<br />

Usman I. Lula<br />

Department <strong>of</strong><br />

Radio<strong>the</strong>rapy,<br />

Poole Hospital,<br />

Longfleet Road, Poole,<br />

BH15 2JB<br />

E usman.lula@poole.nhs.uk<br />

MEMBERS’ NEWS EDITOR<br />

Matt Gwilliam<br />

Cancer Research UK<br />

Cl<strong>in</strong>ical MR Research<br />

Group, <strong>Institute</strong> <strong>of</strong> Cancer<br />

Research <strong>and</strong> Royal<br />

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Trust, Sutton<br />

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INTERNATIONAL EDITOR<br />

(Develop<strong>in</strong>g countries)<br />

Andrew Gammie<br />

Cl<strong>in</strong>ical Eng<strong>in</strong>eer,<br />

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T +44(0)117 950 5050<br />

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INTERNATIONAL EDITOR<br />

(North America)<br />

Richard A. Amos<br />

Department <strong>of</strong> Radiation<br />

<strong>Physics</strong>, The University <strong>of</strong><br />

Texas M.D. Anderson<br />

Cancer Center, 1840 Old<br />

Spanish Trail,Houston,<br />

Texas 77054, U.S.A.<br />

T + 1 713 563 6894<br />

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E richamos@md<strong>and</strong>erson.<br />

org<br />

INTERNATIONAL EDITOR<br />

Ryan D. Lewis<br />

Department <strong>of</strong> Medical<br />

<strong>Physics</strong> <strong>and</strong> Cl<strong>in</strong>ical<br />

<strong>Eng<strong>in</strong>eer<strong>in</strong>g</strong>, Abertawe Bro<br />

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Hospital, Swansea,<br />

Wales, SA2 8QA<br />

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Scope is published quarterly<br />

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Authors <strong>in</strong>structions <strong>and</strong><br />

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Articles should be sent to<br />

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We reserve <strong>the</strong> right to edit<br />

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© IPEM 2012<br />

ISSN 0964-9565<br />

“<br />

Please<br />

contact me if<br />

you wish to<br />

contribute to or<br />

comment on<br />

our magaz<strong>in</strong>e<br />

GEMMA WHITELAW<br />

”<br />

GEMMA WHITELAW EDITOR-IN-CHIEF<br />

COMMENT | SCOPE<br />

AFAREWELL MARC<br />

fter 5 years our Editor Marc<br />

Miquel is stepp<strong>in</strong>g down. I<br />

want to thank Marc for all his<br />

hard work; he has achieved<br />

many th<strong>in</strong>gs whilst Editor,<br />

<strong>in</strong>clud<strong>in</strong>g <strong>the</strong> launch <strong>of</strong> Scope<br />

Onl<strong>in</strong>e (www.scopeonl<strong>in</strong>e.co.<br />

uk), several changes to <strong>the</strong> editorial board <strong>and</strong><br />

launch<strong>in</strong>g <strong>the</strong> Keith Boddy prize for best<br />

educational article. It’ll be a tough act for me to<br />

follow, a daunt<strong>in</strong>g but excit<strong>in</strong>g challenge, <strong>and</strong> I<br />

shall keenly miss <strong>the</strong> guidance <strong>and</strong> direction<br />

Marc has given me whilst I was his deputy.<br />

Thankfully his <strong>of</strong>fice is just across <strong>the</strong> road<br />

from m<strong>in</strong>e, so his unseen h<strong>and</strong> may be visible<br />

until I f<strong>in</strong>d my feet.<br />

This edition <strong>of</strong> Scope <strong>in</strong>cludes a fasc<strong>in</strong>at<strong>in</strong>g<br />

article k<strong>in</strong>dly written for us by Andrew Miller<br />

MP. Here he discusses <strong>the</strong> l<strong>in</strong>ks between<br />

science <strong>and</strong> politics <strong>and</strong> presents all IPEM<br />

members with a challenge, which will<br />

hopefully improve <strong>the</strong> pr<strong>of</strong>ile <strong>of</strong> our field <strong>in</strong><br />

Parliament. Of course what goes for<br />

Westm<strong>in</strong>ster MPs also applies to MSPs <strong>and</strong><br />

representatives <strong>in</strong> <strong>the</strong> o<strong>the</strong>r devolved<br />

assemblies.<br />

If you ever wondered what was lurk<strong>in</strong>g <strong>in</strong><br />

<strong>the</strong> back <strong>of</strong> your department’s archive<br />

cupboard or what your colleagues do outside<br />

<strong>the</strong> <strong>of</strong>fice, <strong>the</strong>n look no fur<strong>the</strong>r than Henry<br />

Lawrence <strong>and</strong> Lynn Mart<strong>in</strong>ez’s article ‘Alice<br />

through <strong>the</strong> archive cupboard’. Who would<br />

have thought extreme iron<strong>in</strong>g <strong>and</strong> free div<strong>in</strong>g<br />

were <strong>in</strong> our collective skill-set?<br />

This issue also heralds o<strong>the</strong>r changes: Robert<br />

Nielson, IPEM’s General Secretary, <strong>and</strong> Peter<br />

Sharp OBE, <strong>the</strong> second President <strong>of</strong> IPEM, are<br />

both retir<strong>in</strong>g. I am sure <strong>the</strong>y will both be<br />

missed by all who have worked with <strong>the</strong>m.<br />

This issue also <strong>in</strong>cludes all <strong>the</strong> regulars such<br />

as news from Richard <strong>and</strong> Usman, a very full<br />

book review section <strong>and</strong> ano<strong>the</strong>r absorb<strong>in</strong>g<br />

chapter <strong>in</strong> Francis Duck’s tales on <strong>the</strong> history<br />

<strong>of</strong> medical physics. This one focuses on<br />

statistical th<strong>in</strong>ker <strong>and</strong> physician Jules Gavarret.<br />

Scope is a magaz<strong>in</strong>e written by <strong>and</strong> for <strong>the</strong><br />

membership <strong>of</strong> IPEM. If you are a member<br />

<strong>the</strong>n it is your magaz<strong>in</strong>e! If you know<br />

someth<strong>in</strong>g that no-one else does or want to<br />

share your po<strong>in</strong>t <strong>of</strong> view more widely amongst<br />

your colleagues <strong>the</strong>n this is <strong>the</strong> forum to jo<strong>in</strong><br />

<strong>in</strong>. So, please contact me if you wish to<br />

contribute to or comment on our magaz<strong>in</strong>e.<br />

SCOPE | SEPTEMBER 2012 | 05


SCOPE | NEWS BY USMAN I. LULA AND RICHARD AMOS<br />

IN BRIEF<br />

HIFU REDUCES<br />

SIDE EFFECTS<br />

Accord<strong>in</strong>g to a study from<br />

UCL UK, 42 patients<br />

received focal HIFU<br />

delivered to cl<strong>in</strong>ically<br />

significant cancer lesions.<br />

Twelve months after<br />

treatment, ur<strong>in</strong>ary <strong>and</strong><br />

erectile function returned to<br />

pre-treatment levels<br />

(Lancet Oncol; doi:<br />

10.1016/S1470-<br />

2045(12)70121-3). Early<br />

evidence on cancer control<br />

was also encourag<strong>in</strong>g.<br />

BRAIN MINI<br />

MAGNETOMETER<br />

In experiments performed at<br />

<strong>the</strong> Physikalisch-Technische<br />

Bundesanstalt <strong>in</strong> Germany,<br />

<strong>the</strong> sensor was used for<br />

magnetoencephalography<br />

(MEG) to measure alpha<br />

waves associated with a<br />

subject open<strong>in</strong>g <strong>and</strong> clos<strong>in</strong>g<br />

<strong>the</strong>ir eyes, <strong>and</strong> signals<br />

result<strong>in</strong>g from h<strong>and</strong><br />

stimulation (Biomed Opt;<br />

doi: 10.1364/BOE.3.000981).<br />

COILS MODULATE<br />

ACTIVITY<br />

Investigators from<br />

Massachusetts have shown<br />

that magnetic stimulation<br />

can generate similar neural<br />

activity to that elicited by <strong>the</strong><br />

electrical impulses used for<br />

DBS. They demonstrated<br />

that a magnetic coil could<br />

elicit neuronal signals <strong>in</strong><br />

ret<strong>in</strong>al cells when implanted<br />

<strong>in</strong>to <strong>the</strong> bra<strong>in</strong> directly above<br />

ret<strong>in</strong>al tissue (Nat Commun;<br />

doi: 10.1038/ncomms1914).<br />

ENGINEERED<br />

MICROVESSELS<br />

Bioeng<strong>in</strong>eers at <strong>the</strong><br />

University <strong>of</strong> Wash<strong>in</strong>gton,<br />

Seattle, have developed a<br />

means to grow small<br />

human blood vessels,<br />

creat<strong>in</strong>g a 3D test bed with<br />

which to study vascular<br />

phenomena such as<br />

angiogenesis <strong>and</strong><br />

thrombosis. The eng<strong>in</strong>eered<br />

vessels could transport<br />

human blood smoothly, even<br />

around corners.<br />

06 | SEPTEMBER 2012 | SCOPE<br />

Institutional experience <strong>of</strong> new<br />

technologies <strong>in</strong> radio<strong>the</strong>rapy<br />

TABLE 1<br />

Category Selections<br />

Demographics<br />

Process step<br />

<strong>of</strong> orig<strong>in</strong>ation<br />

Event type<br />

Simulation<br />

Treatment<br />

plann<strong>in</strong>g<br />

Accord<strong>in</strong>g to <strong>the</strong> Radio<strong>the</strong>rapy Risk<br />

Pr<strong>of</strong>ile report, published by <strong>the</strong><br />

World Health Organization, it is<br />

estimated that treatments for<br />

approximately 3,000 patients were<br />

affected by radio<strong>the</strong>rapy errors<br />

between 1976 <strong>and</strong> 2007. Analysis,<br />

even <strong>of</strong> cl<strong>in</strong>ically <strong>in</strong>significant<br />

events, can uncover QA<br />

deficiencies whilst also provid<strong>in</strong>g a<br />

method to study <strong>the</strong> impact <strong>of</strong><br />

patient safety enhancements.<br />

Date <strong>of</strong> event<br />

Time <strong>of</strong> event (May 2007 onwards)<br />

Number <strong>of</strong> treatment sessions for course<br />

Treatment site<br />

Treatment mach<strong>in</strong>e<br />

Simulation<br />

Treatment plann<strong>in</strong>g<br />

Data entry/transfer<br />

Treatment delivery<br />

Patient measurement<br />

Simulation documentation<br />

Incorrect manual application <strong>of</strong> transmission factor<br />

Calculation error – <strong>in</strong>verse square<br />

Calculation error – o<strong>the</strong>r parameters<br />

MD prescription/planner prescription mis<strong>in</strong>terpretation<br />

Transcription error<br />

O<strong>the</strong>r plann<strong>in</strong>g error<br />

Incorrect manual entry <strong>of</strong> treatment parameters<br />

Data entry Incorrect schedul<strong>in</strong>g <strong>of</strong> treatment fields or treatment<br />

sessions<br />

Incorrect/omitted block, bolus, compensator<br />

Incorrect/omitted wedge<br />

Incorrect/omitted static MLC shape<br />

Incorrect/omitted dynamic MLC shape (IMRT)<br />

Treatment<br />

Incorrect treatment record (chart<strong>in</strong>g)<br />

Incorrect use <strong>of</strong> field parameters or R&V override<br />

Incorrect treatment distance<br />

Incorrect field position (o<strong>the</strong>r than distance)<br />

2.5 mm 3%/3 mm<br />

Event impact<br />

Dosimetric magnitude per treatment session<br />

Dosimetric magnitude over treatment course<br />

Number <strong>of</strong> treatment sessions for which event occurred<br />

Table 1: Patient event demographic <strong>and</strong> event type classification.<br />

Thanks to Margie A. Hunt for supply<strong>in</strong>g <strong>the</strong> image. Figure © Elsevier,<br />

'The impact <strong>of</strong> new technologies on radiation oncology events <strong>and</strong><br />

trends <strong>in</strong> <strong>the</strong> past decade: an <strong>in</strong>stitutional experience’, Margie A. Hunt,<br />

Gerri Pastrana, Howard I. Amols, Aileen Killen, Kaled Alektiar, Int J<br />

Radiat Oncol 2012; article <strong>in</strong> press.<br />

Some previous studies have<br />

shown that new technologies such<br />

as record-<strong>and</strong>-verify (R&V) systems<br />

can both decrease certa<strong>in</strong> event<br />

types <strong>and</strong> <strong>in</strong>crease <strong>the</strong> potential for<br />

o<strong>the</strong>rs, e.g. field parameter/R&V<br />

override <strong>and</strong> chart<strong>in</strong>g events.<br />

The purpose <strong>of</strong> this study, from<br />

<strong>the</strong> Memorial Sloan-Ketter<strong>in</strong>g<br />

Cancer Center <strong>in</strong> New York, was to<br />

review <strong>the</strong> type <strong>and</strong> frequency <strong>of</strong><br />

patient events from external beam<br />

radio<strong>the</strong>rapy over a 10-year period.<br />

This was a period which<br />

encompassed significant<br />

technology change. The study would<br />

allow <strong>the</strong> group to identify trends,<br />

achievements <strong>and</strong> areas for<br />

improvement.<br />

Four radiation oncology process<br />

steps were classified <strong>and</strong> fur<strong>the</strong>r<br />

sub-classified accord<strong>in</strong>g to event<br />

type (table 1): simulation, treatment<br />

plann<strong>in</strong>g, data entry/transfer <strong>and</strong><br />

treatment delivery. Events were<br />

segregated accord<strong>in</strong>g to <strong>the</strong> most<br />

frequently observed types.<br />

There was generally a downward<br />

trend over time <strong>in</strong> <strong>the</strong> event rate<br />

ma<strong>in</strong>ly due to technological<br />

changes, e.g. replacement <strong>of</strong> R&V<br />

system <strong>and</strong> widespread<br />

implementation <strong>of</strong> IMRT. A total <strong>of</strong><br />

284 events were recorded between<br />

2001 <strong>and</strong> 2010. Dur<strong>in</strong>g this time,<br />

approximately 30,600 new<br />

treatment courses <strong>and</strong> 597,000<br />

treatments were delivered, yield<strong>in</strong>g<br />

an event rate <strong>of</strong> 0.93 per cent per<br />

course <strong>and</strong> 0.05 per cent per<br />

treatment session. Frequency <strong>of</strong><br />

event types particularly <strong>in</strong> plann<strong>in</strong>g<br />

<strong>and</strong> treatment delivery changed<br />

significantly over <strong>the</strong> course <strong>of</strong> <strong>the</strong><br />

study. Treatments <strong>in</strong>volv<strong>in</strong>g manual<br />

<strong>in</strong>tervention carried an event risk<br />

four times greater than those<br />

rely<strong>in</strong>g heavily on computer-aided<br />

design <strong>and</strong> delivery.<br />

Areas for improvement <strong>in</strong>clude<br />

manual calculation <strong>and</strong> data entry,<br />

late-day treatments <strong>and</strong> staff<br />

overreliance on computer systems.<br />

The chang<strong>in</strong>g roles <strong>of</strong> R&V systems<br />

<strong>in</strong>herent <strong>in</strong> an electronic medical<br />

record environment, <strong>the</strong><br />

<strong>in</strong>troduction <strong>of</strong> even more complex<br />

technology <strong>and</strong> <strong>the</strong> emergence <strong>of</strong><br />

hyp<strong>of</strong>ractionated treatment<br />

paradigms may all lead to new types<br />

<strong>of</strong> errors.<br />

Fur<strong>the</strong>r improvements <strong>in</strong> patient<br />

safety are imperative, given <strong>the</strong><br />

severe consequences that can arise<br />

from radio<strong>the</strong>rapy errors.<br />

MORE INFORMATION<br />

This work was recently published <strong>in</strong> Int<br />

J Radiat Oncol 2012; article <strong>in</strong> press,<br />

http://dx.doi.org/10.1016/j.ijrobp.<br />

2012.01.042


Detector density impacts<br />

small-field dosimetry<br />

A group <strong>of</strong> researchers at <strong>the</strong><br />

Clatterbridge Cancer Centre are<br />

<strong>in</strong>vestigat<strong>in</strong>g how physical<br />

characteristics <strong>of</strong> detectors<br />

affect small-field dosimetric<br />

measurements. The group<br />

recently published <strong>the</strong>ir report<br />

on <strong>the</strong> impact <strong>of</strong> density <strong>and</strong><br />

atomic composition on <strong>the</strong><br />

response <strong>of</strong> various detectors <strong>in</strong><br />

small fields.<br />

Monte Carlo modell<strong>in</strong>g was<br />

used to exam<strong>in</strong>e variations <strong>of</strong> a<br />

correction factor, F detector ,<br />

with field size. F detector is<br />

def<strong>in</strong>ed as <strong>the</strong> ratio <strong>of</strong> dose to a<br />

water voxel <strong>and</strong> dose to <strong>the</strong><br />

same voxel with <strong>the</strong> density <strong>of</strong><br />

<strong>the</strong> detector.<br />

In total, three detector types<br />

were studied: PTW diamond<br />

detector (density 3.5 g/cm 3 );<br />

PTW 31016 P<strong>in</strong>po<strong>in</strong>t chamber<br />

(0.0012 g/cm 3 ) <strong>and</strong> Sc<strong>and</strong>itronix<br />

unshielded electron diode (2.3<br />

g/cm 3 ). Monte Carlo simulations<br />

modelled a 15 MV beam <strong>in</strong>cident<br />

upon a water phantom with<br />

source-to-surface distance<br />

(SSD) <strong>of</strong> 100 cm. Detector voxels<br />

were located at 5 cm depth with<br />

volumes roughly equal to each<br />

detector’s active volume.<br />

The specific impact <strong>of</strong><br />

detector density on response<br />

was isolated through two sets <strong>of</strong><br />

calculated values for F detector .<br />

The group first calculated<br />

F detector us<strong>in</strong>g <strong>the</strong> density <strong>and</strong><br />

mass radiological properties <strong>of</strong><br />

<strong>the</strong> modelled detectors, <strong>and</strong><br />

<strong>the</strong>n repeated <strong>the</strong> calculations<br />

us<strong>in</strong>g <strong>the</strong> densities <strong>of</strong> diamond,<br />

silicon <strong>and</strong> air, but with mass<br />

radiological properties fixed at<br />

those <strong>of</strong> unit density.<br />

Simulations us<strong>in</strong>g field sizes<br />

rang<strong>in</strong>g from 0.25 to 10 cm<br />

showed that F detector varied<br />

significantly as a function <strong>of</strong> field<br />

size for all three detector types.<br />

The high-density diamond <strong>and</strong><br />

silicon detectors over-read at<br />

small field sizes, relative to<br />

wide-field read<strong>in</strong>gs, whereas<br />

<strong>the</strong> low-density air-filled<br />

detector under-read at small<br />

field sizes. Similar patterns<br />

were observed for <strong>the</strong> densitymodified<br />

water voxels, although<br />

values for F detector converged<br />

to unity for large fields. This<br />

behaviour suggests that <strong>the</strong><br />

variation <strong>of</strong> F detector at small<br />

field sizes arises from<br />

differences <strong>in</strong> detector density,<br />

ra<strong>the</strong>r than atomic composition.<br />

The researchers <strong>the</strong>n<br />

studied <strong>in</strong>tegral doses <strong>of</strong> slit<br />

fields us<strong>in</strong>g <strong>the</strong> silicon diode<br />

<strong>and</strong> P<strong>in</strong>po<strong>in</strong>t detectors. It was<br />

observed that doses measured<br />

along a pr<strong>of</strong>ile varied far less<br />

than central axis doses,<br />

suggest<strong>in</strong>g that, while doses at<br />

<strong>the</strong> centres <strong>of</strong> <strong>in</strong>dividual small<br />

fields would conta<strong>in</strong> errors if left<br />

uncorrected, <strong>in</strong>tegral doses<br />

calculated for VMAT or IMRT<br />

plans (which conta<strong>in</strong> many<br />

overlapp<strong>in</strong>g small fields) would<br />

be approximately correct. This<br />

implies that correct<strong>in</strong>g<br />

measured small-field dose<br />

distributions simply by scal<strong>in</strong>g<br />

<strong>the</strong>m us<strong>in</strong>g central axis<br />

F detector values may lead to<br />

erroneous estimates <strong>of</strong> <strong>the</strong><br />

<strong>in</strong>tegral doses delivered by<br />

techniques us<strong>in</strong>g multiple small<br />

fields. As such, <strong>the</strong> authors<br />

describe <strong>the</strong> ideal small-field<br />

dosimeter as hav<strong>in</strong>g a small<br />

active volume <strong>and</strong> water-like<br />

density.<br />

Work is ongo<strong>in</strong>g to develop a<br />

cavity <strong>the</strong>ory that describes this<br />

density dependence.<br />

A closer look at proton range uncerta<strong>in</strong>ties<br />

The major challenge for<br />

accurate range calculations for<br />

<strong>the</strong>rapeutic proton beams is <strong>the</strong><br />

uncerta<strong>in</strong>ty <strong>in</strong> patient stopp<strong>in</strong>g<br />

power ratios (SPRs). Marg<strong>in</strong>s<br />

along <strong>the</strong> beam axis, both distal<br />

<strong>and</strong> proximal to <strong>the</strong> cl<strong>in</strong>ical<br />

target volume, are used dur<strong>in</strong>g<br />

<strong>the</strong> treatment plann<strong>in</strong>g stage to<br />

account for this uncerta<strong>in</strong>ty <strong>and</strong><br />

ensure target coverage. A value<br />

<strong>of</strong> 3.5 per cent has been<br />

commonly used <strong>in</strong> <strong>the</strong> design <strong>of</strong><br />

<strong>the</strong>se marg<strong>in</strong>s for many years,<br />

but recently a group <strong>of</strong><br />

researchers at <strong>the</strong> University <strong>of</strong><br />

Texas MD Anderson Cancer<br />

Center took a closer look at this<br />

uncerta<strong>in</strong>ty.<br />

Us<strong>in</strong>g a comb<strong>in</strong>ation <strong>of</strong><br />

previously published data <strong>and</strong><br />

new, measured data, <strong>the</strong><br />

researchers assessed five<br />

contributions to SPR<br />

uncerta<strong>in</strong>ty <strong>in</strong> three<br />

representative tissue types:<br />

low-density lung, <strong>in</strong>termediatedensity<br />

s<strong>of</strong>t tissue <strong>and</strong> highdensity<br />

bone. Four <strong>of</strong> <strong>the</strong><br />

contribut<strong>in</strong>g factors correspond<br />

to steps <strong>in</strong> <strong>the</strong> stoichiometric<br />

calibration method, <strong>the</strong> most<br />

commonly used method for<br />

deriv<strong>in</strong>g SPRs for different<br />

tissue types. The fifth orig<strong>in</strong>ates<br />

from <strong>the</strong> dose calculation<br />

algorithm used <strong>in</strong> a treatment<br />

plann<strong>in</strong>g system. Stopp<strong>in</strong>g<br />

NEWS BY USMAN I. LULA AND RICHARD AMOS | SCOPE<br />

F detector as a function <strong>of</strong> field size.<br />

power ratios vary with proton<br />

energy <strong>and</strong> consequently vary<br />

along <strong>the</strong> proton beam path,<br />

whereas common algorithms<br />

ignore this effect.<br />

The researchers used <strong>the</strong><br />

uncerta<strong>in</strong>ties for each tissue<br />

type to estimate <strong>the</strong> composite<br />

range uncerta<strong>in</strong>ty for each<br />

beam <strong>in</strong> <strong>the</strong> treatment plans <strong>of</strong><br />

15 patients who were<br />

undergo<strong>in</strong>g proton <strong>the</strong>rapy for<br />

lung, prostate <strong>and</strong> head <strong>and</strong><br />

neck cancers.<br />

Uncerta<strong>in</strong>ty <strong>in</strong> <strong>in</strong>dividual<br />

tissue types, expressed to one<br />

st<strong>and</strong>ard deviation, ranged from<br />

1.6 per cent for s<strong>of</strong>t tissue to 5.0<br />

per cent for lung. Expressed<br />

MORE INFORMATION<br />

This story was first reported on Medical<br />

<strong>Physics</strong> Web on 11th July:<br />

http://medicalphysicsweb.org/cws/art<br />

icle/research/50234<br />

us<strong>in</strong>g <strong>the</strong> 95th percentile,<br />

beams used to treat lung<br />

tumours exhibited <strong>the</strong> greatest<br />

composite uncerta<strong>in</strong>ty <strong>of</strong> 3.4<br />

per cent. Beams treat<strong>in</strong>g<br />

prostate <strong>and</strong> head <strong>and</strong> neck<br />

cancer both resulted <strong>in</strong> an<br />

uncerta<strong>in</strong>ty <strong>of</strong> 3.0 per cent.<br />

This study highlighted that<br />

<strong>the</strong> currently used value <strong>of</strong> 3.5<br />

per cent is appropriate as a<br />

general recommendation to<br />

account for SPR uncerta<strong>in</strong>ties,<br />

<strong>and</strong> <strong>the</strong> group have no<br />

immediate plans to change<br />

<strong>the</strong>ir cl<strong>in</strong>ical practice.<br />

MORE INFORMATION<br />

This paper was published <strong>in</strong> Phys Med<br />

Biol 2012; 57: 4095–115.<br />

SCOPE | SEPTEMBER 2012 | 07


FEATURE | SCOPE<br />

SCIENCE AND<br />

PARLIAMENT:<br />

A CALL FOR ENGAGEMENT<br />

© r.nagy / Shutterstock<br />

Andrew Miller MP discusses <strong>the</strong> l<strong>in</strong>ks between<br />

science <strong>and</strong> politics, outl<strong>in</strong><strong>in</strong>g a challenge that<br />

all members can be <strong>in</strong>volved with <strong>in</strong> order to<br />

benefit not only <strong>the</strong> pr<strong>of</strong>ession but also<br />

healthcare <strong>and</strong> <strong>the</strong> whole science community<br />

Irecently spent a weekend at<br />

Ditchley Park <strong>in</strong> Oxfordshire,<br />

a house that has not only been<br />

graced with great names like<br />

W<strong>in</strong>ston Churchill among its<br />

visitors, but has been <strong>the</strong><br />

home <strong>of</strong> high-level bra<strong>in</strong> storm<strong>in</strong>g<br />

sessions amongst experts on many<br />

subjects over <strong>the</strong> last 60 years.<br />

Initially Sir David Wills, who<br />

conceived <strong>the</strong> idea <strong>and</strong> at that time<br />

owned <strong>the</strong> house, saw it as a venue<br />

for improv<strong>in</strong>g relations across <strong>the</strong><br />

Atlantic, especially between our<br />

respective governments here <strong>and</strong> <strong>in</strong><br />

<strong>the</strong> US.<br />

Today <strong>the</strong> transatlantic dimension<br />

is just as strong but many o<strong>the</strong>r<br />

nations participate <strong>in</strong> try<strong>in</strong>g to f<strong>in</strong>d<br />

solutions to problems that face us<br />

all. That is why I leapt at <strong>the</strong><br />

opportunity when I was <strong>in</strong>vited to<br />

attend a sem<strong>in</strong>ar entitled ‘Putt<strong>in</strong>g<br />

Science, Government, Bus<strong>in</strong>ess <strong>and</strong><br />

Innovation Toge<strong>the</strong>r’. All <strong>of</strong> my<br />

adult life I have been fasc<strong>in</strong>ated with<br />

<strong>the</strong> challenge <strong>of</strong> how to use science<br />

<strong>in</strong> a way that benefits people, <strong>and</strong><br />

also <strong>the</strong> vexed question <strong>of</strong> engag<strong>in</strong>g<br />

our society <strong>in</strong> <strong>the</strong> scientific<br />

challenges <strong>of</strong> today <strong>and</strong> help<strong>in</strong>g<br />

people without a science<br />

background to underst<strong>and</strong> <strong>the</strong><br />

relevance <strong>of</strong> research that is<br />

undertaken. Those challenges exist<br />

throughout our society but are<br />

especially acute <strong>in</strong> Parliament. MPs<br />

are expected to take important<br />

decisions not just about <strong>the</strong> science<br />

budget but about <strong>the</strong> application <strong>of</strong><br />

science throughout <strong>the</strong> country we<br />

seek to represent, dabbl<strong>in</strong>g <strong>in</strong> areas<br />

rang<strong>in</strong>g from education through to<br />

why we should <strong>in</strong>vest <strong>in</strong> CERN or<br />

<strong>the</strong> next generation <strong>of</strong> astronomy.<br />

You do not need to know much<br />

about <strong>the</strong> political process to realise<br />

that this presents a challenge;<br />

politics is all about priorities. But as<br />

only about 10 per cent <strong>of</strong> <strong>the</strong> House<br />

<strong>of</strong> Commons (a figure that has<br />

stayed relatively stable for some<br />

time) have ever worked <strong>in</strong> an STEM<br />

discipl<strong>in</strong>e, engag<strong>in</strong>g with MPs is<br />

essential.<br />

At <strong>the</strong> end <strong>of</strong> <strong>the</strong> Ditchley Park<br />

weekend we were each asked to sum<br />

up <strong>in</strong> one sentence what we got out<br />

<strong>of</strong> <strong>the</strong> event. In my case I learnt a<br />

tremendous amount but it<br />

conv<strong>in</strong>ced me more than ever <strong>of</strong> <strong>the</strong><br />

importance <strong>of</strong> cont<strong>in</strong>u<strong>in</strong>g <strong>the</strong><br />

longst<strong>and</strong><strong>in</strong>g work I am <strong>in</strong>volved <strong>in</strong><br />

with<strong>in</strong> Parliament to help build a<br />

bridge between science <strong>and</strong> politics.<br />

SCIENCE IN PARLIAMENT<br />

There are some stunn<strong>in</strong>gly good<br />

arrangements <strong>in</strong> place, such as <strong>the</strong><br />

Royal Society’s pair<strong>in</strong>g scheme,<br />

which <strong>of</strong>fers Fellows an opportunity<br />

to pair with an MP or civil servant<br />

▼<br />

SCOPE | SEPTEMBER 2012 | 09


▼<br />

SCOPE | FEATURE<br />

<strong>and</strong> both spend time toge<strong>the</strong>r <strong>in</strong> <strong>the</strong>ir<br />

respective environments. My limited<br />

knowledge <strong>of</strong> nanotechnology came<br />

from such an experience. There are<br />

also schemes like Newton’s Apple,<br />

devised <strong>and</strong> run passionately by<br />

Michael Elves, a man with a<br />

dist<strong>in</strong>guished <strong>in</strong>dustrial <strong>and</strong><br />

academic record who br<strong>in</strong>gs young<br />

scientists <strong>in</strong>to <strong>the</strong> House.<br />

Similarly <strong>the</strong>re are events like <strong>the</strong><br />

Parliamentary L<strong>in</strong>ks Day, now<br />

organised by <strong>the</strong> Society <strong>of</strong> Biology<br />

on behalf <strong>of</strong> <strong>the</strong> science <strong>and</strong><br />

eng<strong>in</strong>eer<strong>in</strong>g community, <strong>and</strong><br />

supported by <strong>the</strong> <strong>Institute</strong> <strong>of</strong> <strong>Physics</strong>,<br />

<strong>the</strong> Royal Society, <strong>the</strong> Royal Society<br />

<strong>of</strong> Ed<strong>in</strong>burgh, <strong>the</strong> Royal Academy <strong>of</strong><br />

<strong>Eng<strong>in</strong>eer<strong>in</strong>g</strong>, <strong>the</strong> Biochemical Society,<br />

<strong>the</strong> Society for Experimental Biology,<br />

<strong>the</strong> Society for Applied Microbiology,<br />

<strong>the</strong> British Pharmacological Society,<br />

<strong>the</strong> Astronomical Society, <strong>the</strong><br />

Geological Society, <strong>the</strong> Council for<br />

<strong>the</strong> Ma<strong>the</strong>matical Sciences, <strong>the</strong> New<br />

<strong>Eng<strong>in</strong>eer<strong>in</strong>g</strong> Foundation, <strong>the</strong> Royal<br />

Society <strong>of</strong> Chemistry, <strong>the</strong> Campaign<br />

for Science <strong>and</strong> <strong>Eng<strong>in</strong>eer<strong>in</strong>g</strong> <strong>and</strong> <strong>the</strong><br />

Parliamentary <strong>and</strong> Scientific<br />

Committee. This year more than 120<br />

people came to <strong>the</strong> House to focus on<br />

a series <strong>of</strong> discussions around science<br />

<strong>and</strong> sport; <strong>the</strong> subject was obviously<br />

not chosen by accident!<br />

The Speaker <strong>of</strong> <strong>the</strong> House <strong>of</strong><br />

Commons, Rt Hon John Bercow MP,<br />

opened <strong>the</strong> meet<strong>in</strong>g. He is quoted on<br />

<strong>the</strong> Society <strong>of</strong> Biology’s website as<br />

say<strong>in</strong>g: ‘I know, from my unique<br />

vantage po<strong>in</strong>t <strong>in</strong> <strong>the</strong> House, that<br />

Members on all sides cont<strong>in</strong>ue to<br />

raise issues that have a scientific<br />

aspect to <strong>the</strong>m.<br />

‘It is all <strong>the</strong> more important that<br />

every Member <strong>of</strong> Parliament should<br />

be able to benefit from non-partisan<br />

assistance <strong>of</strong> <strong>the</strong> k<strong>in</strong>d <strong>of</strong>fered by<br />

pr<strong>of</strong>essional scientific bodies like <strong>the</strong><br />

Society <strong>of</strong> Biology, <strong>the</strong> <strong>Institute</strong> <strong>of</strong><br />

<strong>Physics</strong>, <strong>the</strong> Royal Society <strong>of</strong><br />

Chemistry <strong>and</strong> many o<strong>the</strong>rs with<br />

<strong>the</strong>ir proven commitment to public<br />

<strong>in</strong>terest.’<br />

The first All Party Parliamentary<br />

Group was <strong>the</strong> Parliamentary <strong>and</strong><br />

Scientific Committee (P&SC). All<br />

Party Groups are made up <strong>of</strong> MPs<br />

<strong>and</strong> peers work<strong>in</strong>g toge<strong>the</strong>r across<br />

parties on areas <strong>of</strong> common <strong>in</strong>terest.<br />

The P&SC engages regularly with <strong>the</strong><br />

science community <strong>and</strong> publishes its<br />

quarterly magaz<strong>in</strong>e entitled Science<br />

<strong>in</strong> Parliament.<br />

One <strong>of</strong> <strong>the</strong> more recent<br />

<strong>in</strong>novations is ‘SET for Brita<strong>in</strong>’,<br />

10 | SEPTEMBER 2012 | SCOPE<br />

orig<strong>in</strong>ated by <strong>the</strong> late Dr Eric<br />

Wharton <strong>and</strong> cont<strong>in</strong>ued by <strong>the</strong><br />

former MP for Bristol Dr Doug<br />

Naysmith. The event is organised<br />

<strong>and</strong> run by staff <strong>of</strong> <strong>the</strong> P&SC with a<br />

tremendous amount <strong>of</strong> help from<br />

learned societies <strong>and</strong> private<br />

companies. This successfully br<strong>in</strong>gs<br />

a great poster competition to <strong>the</strong><br />

House, ga<strong>the</strong>r<strong>in</strong>g early career<br />

researchers toge<strong>the</strong>r from a number<br />

<strong>of</strong> discipl<strong>in</strong>es <strong>and</strong> most importantly<br />

gett<strong>in</strong>g <strong>the</strong>m engaged with MPs.<br />

Both Houses have a Science <strong>and</strong><br />

Technology Select Committee<br />

work<strong>in</strong>g on a range <strong>of</strong> topics. The<br />

Commons Committee that I chair is<br />

currently work<strong>in</strong>g on a number <strong>of</strong><br />

projects <strong>in</strong>clud<strong>in</strong>g, for example, a<br />

report on medical implants. We are<br />

supported by a team <strong>of</strong> extremely<br />

well qualified science specialists <strong>and</strong><br />

clerks. (The name clerk <strong>in</strong> Parliament<br />

applies to a highly qualified advisor<br />

not simply a scribe.)<br />

Parliament is also served by<br />

brilliant librarians <strong>and</strong> <strong>the</strong><br />

Parliamentary Office <strong>of</strong> Science <strong>and</strong><br />

Technology (POST). The latter is<br />

Parliament’s <strong>in</strong>-house source <strong>of</strong><br />

<strong>in</strong>dependent, balanced <strong>and</strong><br />

accessible analysis <strong>of</strong> public policy<br />

issues related to science <strong>and</strong><br />

technology. The organisation has<br />

some permanent staff as well as a<br />

network <strong>of</strong> seconded extremely<br />

bright young scientists.<br />

WHAT ELSE IS NEEDED?<br />

That all sounds like a long list but it<br />

does not alter <strong>the</strong> fact that MPs are<br />

under permanent pressure to be<br />

do<strong>in</strong>g o<strong>the</strong>r th<strong>in</strong>gs <strong>and</strong> <strong>the</strong> degree <strong>of</strong><br />

engagement with science <strong>and</strong> science<br />

policy is somewhat limited. So this is<br />

where you come <strong>in</strong>!<br />

IPEM members are work<strong>in</strong>g <strong>in</strong> a<br />

discipl<strong>in</strong>e that every politician,<br />

irrespective <strong>of</strong> <strong>the</strong>ir orig<strong>in</strong>al tra<strong>in</strong><strong>in</strong>g,<br />

will see as relevant to <strong>the</strong> society<br />

with<strong>in</strong> which we live. Whilst <strong>the</strong><br />

scientists <strong>and</strong> technicians with<strong>in</strong> <strong>the</strong><br />

<strong>Institute</strong> rarely get a mention <strong>in</strong> <strong>the</strong><br />

popular press compared with, say,<br />

doctors <strong>and</strong> nurses, anyone who<br />

has ever visited a hospital<br />

ei<strong>the</strong>r pr<strong>of</strong>essionally or as a<br />

patient will readily see <strong>the</strong><br />

importance <strong>of</strong> <strong>the</strong><br />

underly<strong>in</strong>g science that<br />

supports our health system.<br />

So each <strong>and</strong> every one <strong>of</strong> you<br />

are <strong>in</strong> a strong position to<br />

help address <strong>the</strong> challenge I<br />

have described. Whe<strong>the</strong>r you<br />

ABOVE LEFT<br />

Ditchley Park<br />

<strong>in</strong> Oxfordshire.<br />

▼<br />

ABOVE RIGHT<br />

Parliamentary<br />

L<strong>in</strong>ks Day:<br />

Julian Huppert<br />

MP, Rt Hon John<br />

Bercow MP,<br />

Andrew Miller<br />

MP <strong>and</strong> Dame<br />

Nancy Rothwell.<br />

▼<br />

work <strong>in</strong> a hospital or are <strong>in</strong>volved <strong>in</strong><br />

design<strong>in</strong>g or manufactur<strong>in</strong>g tools for<br />

<strong>the</strong> health service I simply <strong>in</strong>vite you<br />

to engage with your own local MP<br />

<strong>and</strong> make sure that he or she<br />

underst<strong>and</strong>s <strong>the</strong> importance <strong>of</strong> <strong>the</strong><br />

underly<strong>in</strong>g science that supports <strong>the</strong><br />

great <strong>in</strong>novations that are go<strong>in</strong>g on <strong>in</strong><br />

healthcare on a daily basis. Don’t just<br />

talk to MPs about healthcare but<br />

about how modern science today<br />

crosses discipl<strong>in</strong>es. Without people<br />

like Alan Tur<strong>in</strong>g would we have<br />

mapped <strong>the</strong> genome so quickly? In<br />

<strong>the</strong> great advances we have seen <strong>in</strong><br />

scann<strong>in</strong>g <strong>and</strong> x-ray tools <strong>the</strong><br />

crossover between <strong>the</strong> needs <strong>of</strong> highend<br />

eng<strong>in</strong>eer<strong>in</strong>g companies work<strong>in</strong>g<br />

<strong>in</strong> a whole range <strong>of</strong> <strong>in</strong>dustrial<br />

discipl<strong>in</strong>es <strong>and</strong> <strong>the</strong> application <strong>of</strong> <strong>the</strong><br />

technologies for <strong>the</strong> benefit <strong>of</strong> human<br />

health are issues that each <strong>of</strong> you can<br />

wax considerably more lyrically than<br />

I, for example on how 3D pr<strong>in</strong>t<strong>in</strong>g is<br />

go<strong>in</strong>g to have a significant role <strong>in</strong><br />

orthopaedics. But <strong>the</strong> key<br />

message to get over is that<br />

medic<strong>in</strong>e does not exist <strong>in</strong><br />

isolation from <strong>the</strong> rest <strong>of</strong> <strong>the</strong><br />

science base <strong>and</strong> <strong>in</strong>deed<br />

could not.<br />

This is not just a challenge I<br />

am lay<strong>in</strong>g down to IPEM<br />

members. I th<strong>in</strong>k that it should be


© Ralph Loch 2010<br />

<strong>the</strong> responsibility <strong>of</strong> every scientist to<br />

engage with <strong>the</strong> political community<br />

so that MPs get directly from <strong>the</strong><br />

people <strong>the</strong>y are represent<strong>in</strong>g <strong>the</strong><br />

importance <strong>of</strong> work that has been<br />

undertaken under <strong>the</strong>ir very noses <strong>in</strong><br />

<strong>the</strong>ir own constituencies. The more<br />

we can make this happen <strong>the</strong> more<br />

optimistic I would be that this<br />

government <strong>and</strong> future governments<br />

will take <strong>the</strong> science budget seriously.<br />

The o<strong>the</strong>r end <strong>of</strong> <strong>the</strong> telescope is <strong>of</strong><br />

course what <strong>the</strong> <strong>Institute</strong> can do to<br />

match <strong>the</strong> work that has been<br />

undertaken by o<strong>the</strong>r learned societies<br />

directly with<strong>in</strong> Parliament.<br />

Stephen Keevil <strong>and</strong> o<strong>the</strong>rs are<br />

frequently knock<strong>in</strong>g on my door <strong>and</strong><br />

those <strong>of</strong> my colleagues to press <strong>the</strong><br />

case for <strong>the</strong> <strong>Institute</strong>. Many <strong>of</strong> <strong>the</strong><br />

larger or perhaps more well-<strong>of</strong>f<br />

societies have pr<strong>of</strong>essionalised that<br />

process; some hire <strong>in</strong> external<br />

government affairs specialists, some<br />

employ <strong>the</strong>ir own. Some societies<br />

collaborate toge<strong>the</strong>r <strong>and</strong> share <strong>the</strong><br />

costs <strong>of</strong> a person to front <strong>the</strong>ir<br />

activities <strong>in</strong> Parliament. And <strong>the</strong>re is<br />

a high degree <strong>of</strong> co-operation<br />

between various organisations, for<br />

example <strong>the</strong> L<strong>in</strong>ks Day that I<br />

mentioned earlier <strong>in</strong>volves people<br />

from earth sciences, biology, physics,<br />

eng<strong>in</strong>eer<strong>in</strong>g <strong>and</strong> chemistry, etc.<br />

“<br />

They<br />

have sp<strong>in</strong><strong>of</strong>f<br />

benefits to<br />

<strong>the</strong> whole<br />

<strong>of</strong> <strong>the</strong><br />

health<br />

mach<strong>in</strong>e<br />

”<br />

So my second challenge to <strong>the</strong><br />

<strong>Institute</strong> is to <strong>in</strong>vite you to ask <strong>the</strong><br />

question: how do you get a better<br />

voice <strong>in</strong> Parliament?<br />

Both <strong>of</strong> <strong>the</strong> challenges I am sett<strong>in</strong>g<br />

out for you are clearly not just good<br />

for your own pr<strong>of</strong>ession but <strong>the</strong>y<br />

have sp<strong>in</strong>-<strong>of</strong>f benefits to <strong>the</strong> whole <strong>of</strong><br />

<strong>the</strong> health mach<strong>in</strong>e, as well as much<br />

more broadly across <strong>the</strong> science<br />

community.<br />

F<strong>in</strong>ally, some <strong>of</strong> you will come<br />

across difficult cases (I mean <strong>the</strong> MPs<br />

not <strong>the</strong> patients) but each <strong>of</strong> you will<br />

have anecdotes that will help get <strong>the</strong><br />

message across. For example, when I<br />

was be<strong>in</strong>g treated by a consultant<br />

who has now retired I went to one<br />

appo<strong>in</strong>tment <strong>and</strong> found him <strong>in</strong> a<br />

very excited mood.<br />

He said, ‘Andrew, you’re<br />

<strong>in</strong>terested <strong>in</strong> technology; come <strong>and</strong><br />

have a look at my new system’.<br />

Picture archiv<strong>in</strong>g had just been<br />

switched on <strong>in</strong> his hospital <strong>and</strong> for<br />

<strong>the</strong> first time he was able to send me<br />

for an x-ray, hav<strong>in</strong>g just read my<br />

notes, <strong>and</strong> to have it <strong>in</strong> front <strong>of</strong> him<br />

as I came up through <strong>the</strong> queue <strong>of</strong><br />

patients. He played with his<br />

computer <strong>and</strong> showed me how he<br />

could enlarge <strong>the</strong>se shots <strong>of</strong> various<br />

bits <strong>of</strong> me <strong>and</strong> alter <strong>the</strong> contrasts to<br />

hone <strong>in</strong> <strong>in</strong> more detail. The net result<br />

FEATURE | SCOPE<br />

was a more satisfactory outcome<br />

because he could better <strong>in</strong>terpret <strong>the</strong><br />

data <strong>and</strong> equally importantly, as a<br />

result <strong>of</strong> <strong>the</strong> fact that he no longer has<br />

to re-read <strong>the</strong> patient’s file due to <strong>the</strong><br />

long gap between be<strong>in</strong>g sent <strong>of</strong>f for<br />

an x-ray <strong>and</strong> <strong>the</strong> <strong>in</strong>formation gett<strong>in</strong>g<br />

back to him, he saw real productivity<br />

improvements <strong>and</strong> was able, he<br />

guessed, to see at least one more<br />

patient <strong>in</strong> each cl<strong>in</strong>ic session. There<br />

was a consultant who understood <strong>the</strong><br />

relevance <strong>of</strong> technology <strong>and</strong> here is a<br />

patient who was grateful for its<br />

application.<br />

There are hundreds more such<br />

anecdotes that are directly related to<br />

health improvement <strong>in</strong> every s<strong>in</strong>gle<br />

constituency. MPs need to know<br />

about <strong>the</strong>m <strong>and</strong> <strong>the</strong> best people to<br />

talk to MPs about technologies like<br />

this are people like you. n<br />

FURTHER READING<br />

Science <strong>in</strong> Parliament<br />

www.vm<strong>in</strong>e.net/science<strong>in</strong>parliament<br />

SET for Brita<strong>in</strong><br />

www.setforbrita<strong>in</strong>.org.uk<br />

House <strong>of</strong> Commons Select<br />

Committee <strong>of</strong> Science <strong>and</strong> Technology<br />

www.parliament.uk/science<br />

Parliamentary <strong>of</strong>fice <strong>of</strong><br />

Science <strong>and</strong> Technology (POST)<br />

www.parliament.uk/post<br />

SCOPE | SEPTEMBER 2012 | 11


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All images © Henry Lawrence <strong>and</strong> Lynn Mart<strong>in</strong>ez, 2012<br />

o<strong>the</strong>r’, said Alice, ‘I’ll<br />

never get this tra<strong>in</strong><strong>in</strong>g<br />

portfolio f<strong>in</strong>ished until<br />

I can f<strong>in</strong>d that ion<br />

recomb<strong>in</strong>ation paper<br />

by Havercr<strong>of</strong>t’. 1 B‘<br />

She had looked everywhere,<br />

Medl<strong>in</strong>e, Scopus, <strong>and</strong> worst <strong>of</strong> all she<br />

remembered see<strong>in</strong>g a dog-eared copy<br />

ly<strong>in</strong>g somewhere around <strong>the</strong><br />

department.<br />

Her eyes drifted to <strong>the</strong> archive<br />

cupboard. Nobody ever used it;<br />

maybe once a year th<strong>in</strong>gs no-one had<br />

<strong>the</strong> courage to throw away got<br />

dumped <strong>the</strong>re. It was worth a try.<br />

She opened <strong>the</strong> door. Slowly, <strong>the</strong>n<br />

with an unstoppable momentum,<br />

generations <strong>of</strong> reports, graphs <strong>and</strong><br />

FIGURE 1.<br />

Was that <strong>the</strong><br />

sound <strong>of</strong> music <strong>in</strong><br />

<strong>the</strong> distance?<br />

▼<br />

charts stirred, <strong>and</strong> <strong>in</strong> one long, slow<br />

movement avalanched over her.<br />

She was completely covered, <strong>and</strong><br />

all went dark. Frantically she waved<br />

her arms around, push<strong>in</strong>g papers<br />

hi<strong>the</strong>r <strong>and</strong> thi<strong>the</strong>r. At last she saw<br />

light, <strong>and</strong> looked up.<br />

She turned around. There was no<br />

sign <strong>of</strong> <strong>the</strong> cupboard! Or her <strong>of</strong>fice.<br />

The whole medical physics<br />

department <strong>of</strong> Lymeswold Hospital<br />

had been transformed <strong>in</strong>to a vast,<br />

brood<strong>in</strong>g forest.<br />

She stra<strong>in</strong>ed her ears. Was that<br />

music <strong>in</strong> <strong>the</strong> distance? It sounded like<br />

some sort <strong>of</strong> barn dance b<strong>and</strong>,<br />

banjos, 42 m<strong>and</strong>ol<strong>in</strong>s, 19,27 a flute, 37<br />

highl<strong>and</strong> pipes, 71 a ukulele 72 <strong>and</strong> a<br />

fiddle. 2,58<br />

FEATURE | SCOPE<br />

Alice through <strong>the</strong><br />

archive cupboard<br />

Henry Lawrence (Ipswich Hospital) reveals what your colleagues really get up to <strong>in</strong><br />

<strong>the</strong>ir spare time! Illustrated by Lynn Mart<strong>in</strong>ez (Royal Free Hospital, London)<br />

‘Golly’, thought Alice, ‘that<br />

sounds fun!’. I like to do a little<br />

Appalachian clog danc<strong>in</strong>g65 myself.<br />

I’ll go <strong>and</strong> ask <strong>the</strong>m where I am. As<br />

she came to <strong>the</strong> brow <strong>of</strong> a hill she<br />

looked down at a full-blown barn<br />

dance27 <strong>in</strong> operation. Her experienced<br />

ear told her straightaway… ‘That’s<br />

North West Morris, 6 I can’t dance<br />

that! Maybe if <strong>the</strong>y did some Welsh<br />

folk dance7 I might st<strong>and</strong> a chance’.<br />

No sooner did that thought cross<br />

her m<strong>in</strong>d when <strong>the</strong> b<strong>and</strong> stopped,<br />

<strong>and</strong> a woman <strong>in</strong> full seventeenthcentury<br />

costume brought her lute15 out from with<strong>in</strong> <strong>the</strong> flow<strong>in</strong>g folds <strong>of</strong><br />

her woven17 gown <strong>and</strong> <strong>the</strong> lilt<strong>in</strong>g<br />

notes <strong>of</strong> Greensleeves filled <strong>the</strong> air,<br />

jo<strong>in</strong>ed by tenor <strong>and</strong> bass recorders. 66<br />

▼<br />

SCOPE | SEPTEMBER 2012 | 13


▼<br />

And when <strong>the</strong> choirs 5,11,16,20,23,33,64 jo<strong>in</strong>ed<br />

<strong>in</strong>, Alice was <strong>in</strong> seventh heaven. ‘But<br />

she shouldn’t have been do<strong>in</strong>g<br />

Regency dance ‘, 6 thought Alice.<br />

‘That’s all wrong.’<br />

‘What is this place?’, she<br />

wondered. ‘And who are all <strong>the</strong>se<br />

people? Such a change from all those<br />

bor<strong>in</strong>g people at work.’<br />

The whirr <strong>of</strong> a Super-8 movie<br />

camera brought her round. 30 ‘It’s an<br />

arty film’, <strong>the</strong> operator said, ‘<strong>and</strong><br />

we’re record<strong>in</strong>g <strong>the</strong> soundtrack’. She<br />

beckoned, <strong>and</strong> toge<strong>the</strong>r <strong>the</strong>y peeped<br />

through a w<strong>in</strong>dow.<br />

Inside was a complete record<strong>in</strong>g<br />

studio, 71 <strong>and</strong> a jazz b<strong>and</strong> 12 was hitt<strong>in</strong>g<br />

a groove with a long solo. A bunch <strong>of</strong><br />

14 | SEPTEMBER 2012 | SCOPE<br />

hangers-on sat beh<strong>in</strong>d <strong>the</strong> record<strong>in</strong>g<br />

desk. Some were do<strong>in</strong>g crosswords, 11<br />

o<strong>the</strong>rs origami, 53 balloon modell<strong>in</strong>g 52<br />

or play<strong>in</strong>g board games; 3 that solo<br />

must have been go<strong>in</strong>g on a long time!<br />

The film-maker panned her<br />

camera round; a well honed<br />

muscleman 31 was bounc<strong>in</strong>g up <strong>and</strong><br />

down on a trampol<strong>in</strong>e. 5 Some actors 54<br />

were practic<strong>in</strong>g ice skat<strong>in</strong>g 35 on <strong>the</strong><br />

pond, throw<strong>in</strong>g Frisbees. 55 A girl was<br />

star<strong>in</strong>g <strong>in</strong>tently at a tra<strong>in</strong> set. 19,35<br />

‘Why is she play<strong>in</strong>g with that?’,<br />

asked Alice. ‘She’s secretly<br />

committed to sav<strong>in</strong>g <strong>the</strong><br />

environment‘, 10 replied <strong>the</strong> filmmaker.<br />

‘She believes <strong>in</strong> “Small is<br />

Beautiful”.’<br />

“<br />

‘Such<br />

a change<br />

from all<br />

those<br />

bor<strong>in</strong>g<br />

people at<br />

work’<br />

”<br />

There is someth<strong>in</strong>g about <strong>the</strong><br />

smell <strong>of</strong> homemade bread. 18,55 It was<br />

waft<strong>in</strong>g from beh<strong>in</strong>d <strong>the</strong> bushes.<br />

Alice was <strong>the</strong>re <strong>in</strong> a flash, <strong>in</strong> front <strong>of</strong><br />

a table laid out with cakes,<br />

wonderfully decorated, 41 show<strong>in</strong>g <strong>the</strong><br />

sugar craft artist’s 42 skills to<br />

perfection. And <strong>in</strong> <strong>the</strong> middle, an<br />

enormous jar <strong>of</strong> award-w<strong>in</strong>n<strong>in</strong>g<br />

marmalade! 52<br />

It was a market. Next to <strong>the</strong> cake<br />

stall were all sorts <strong>of</strong> people sell<strong>in</strong>g<br />

<strong>the</strong>ir wares. Someone was sell<strong>in</strong>g<br />

felt, 17 lovely crochet toys 37 <strong>and</strong> lea<strong>the</strong>r<br />

craft. 42 A gallery stall was show<strong>in</strong>g a<br />

mixed exhibition <strong>of</strong> photographs, 18,28<br />

pa<strong>in</strong>t<strong>in</strong>gs 40 <strong>and</strong> sketches. 17 Ano<strong>the</strong>r<br />

was piled high with pottery 39,42 that


would not have been out <strong>of</strong> place <strong>in</strong><br />

any Cornish seaside shop. And <strong>the</strong>re<br />

was even a detector calibration jig, all<br />

built out <strong>of</strong> Lego. 21<br />

But best <strong>of</strong> all was <strong>the</strong> beaded<br />

jewellery. 2 ‘Who makes that?’, she<br />

asked. ‘No-one knows’, replied <strong>the</strong><br />

cuckoo clockmaker. 56 ‘But I hear she<br />

is gett<strong>in</strong>g married on top <strong>of</strong> <strong>the</strong><br />

mounta<strong>in</strong>.‘ 2 ‘Oh goody’, giggled<br />

Alice. ‘I’d love to come.’<br />

So <strong>of</strong>f <strong>the</strong>y went, some<br />

hik<strong>in</strong>g, 19,47,61,66 some on mounta<strong>in</strong><br />

bikes, 28,51,62,69 some on horseback. 45,68 A<br />

sheep farmer seemed to be danc<strong>in</strong>g<br />

<strong>the</strong> Salsa. 67 When <strong>the</strong>y came to a<br />

clear<strong>in</strong>g some <strong>of</strong> <strong>the</strong> guys started<br />

kick<strong>in</strong>g a ball about. 8,60,63<br />

FIGURE 2.<br />

[ LEFT]<br />

And <strong>the</strong>re stood<br />

<strong>the</strong> vicar,<br />

vestments<br />

blow<strong>in</strong>g <strong>in</strong> <strong>the</strong><br />

w<strong>in</strong>d.<br />

▼<br />

FIGURE 3.<br />

[ RIGHT]<br />

A sweat<strong>in</strong>g<br />

woman was<br />

balanc<strong>in</strong>g on her<br />

head.<br />

▼<br />

‘I want to play’, shouted Alice, but<br />

ladies don’t play football. So<br />

everyone played Korfball 32 <strong>and</strong><br />

rounders 8,13 <strong>in</strong>stead.<br />

Suddenly, some characters who<br />

looked like <strong>the</strong>y came out <strong>of</strong> a roleplay<strong>in</strong>g<br />

game 3 stood on <strong>the</strong> path <strong>in</strong><br />

full armour, but one <strong>of</strong> <strong>the</strong> horsemen<br />

tucked his lance under his arm <strong>and</strong><br />

charged. 45 The Aikido warriors 16,43<br />

drew <strong>the</strong>ir swords, but it was <strong>the</strong><br />

kung fu fighters 2 who caused <strong>the</strong> role<br />

players to retreat, <strong>and</strong> recommence<br />

<strong>the</strong>ir Ars Magica game <strong>in</strong> <strong>the</strong> dark<br />

recesses <strong>of</strong> <strong>the</strong> palace.<br />

They came to a wide, slow flow<strong>in</strong>g<br />

river. Some kayaks <strong>and</strong> boats 9,14,19<br />

were head<strong>in</strong>g upstream; <strong>the</strong>y<br />

FEATURE | SCOPE<br />

shouted <strong>and</strong> a sail<strong>in</strong>g boat57 <strong>of</strong>fered<br />

to take <strong>the</strong>m across. But just as she<br />

stepped onboard, Alice slipped <strong>and</strong><br />

fell <strong>in</strong>to <strong>the</strong> dark, murky water. A<br />

scuba diver28 came straight to her<br />

aid, but it was <strong>the</strong> bog snorkell<strong>in</strong>g<br />

champion34 who found her. Toge<strong>the</strong>r<br />

<strong>the</strong>y brought her splutter<strong>in</strong>g to <strong>the</strong><br />

surface.<br />

‘Lucky I can do breath-hold free<br />

div<strong>in</strong>g‘, 34 thought Alice as she broke<br />

<strong>the</strong> surface.<br />

On <strong>the</strong> o<strong>the</strong>r side <strong>of</strong> <strong>the</strong> river,<br />

stretch<strong>in</strong>g high <strong>in</strong>to <strong>the</strong> sky, stood<br />

<strong>the</strong> mounta<strong>in</strong>s.<br />

‘Good that I’ve done a bit <strong>of</strong><br />

climb<strong>in</strong>g’, thought Alice. And so had<br />

<strong>the</strong> o<strong>the</strong>rs, 2 <strong>and</strong> <strong>the</strong>re were some<br />

scoutmasters too, 14,24,41 so everyone<br />

was under safe leadership. 24,40,59,70 The<br />

paths looked like a maze, 11 but<br />

someone had a map; a secret map <strong>of</strong><br />

all <strong>the</strong> footpaths2 that had been<br />

made cl<strong>and</strong>est<strong>in</strong>ely <strong>and</strong> h<strong>and</strong>ed<br />

down through generations.<br />

Thick clouds were form<strong>in</strong>g on <strong>the</strong><br />

top <strong>of</strong> <strong>the</strong> mounta<strong>in</strong>. ‘They’re not<br />

clouds’, said Alice. She had done<br />

research on extreme wea<strong>the</strong>r, 49 <strong>and</strong><br />

knew it was a volcano. But <strong>the</strong><br />

sound <strong>of</strong> church bells2,11,29 spurred<br />

<strong>the</strong>m on, <strong>and</strong> <strong>the</strong> orchestra, 2,22,26,36,37<br />

played <strong>the</strong> wedd<strong>in</strong>g march as <strong>the</strong>y<br />

neared <strong>the</strong> top. She had never seen<br />

so many church <strong>of</strong>ficials. 2,22,26,36 But<br />

which one was <strong>the</strong> vicar?<br />

Almost on cue <strong>the</strong> church doors<br />

opened to <strong>the</strong> <strong>in</strong>sistent riff <strong>of</strong><br />

Hawkw<strong>in</strong>d’s ‘Silver Mach<strong>in</strong>e’, <strong>the</strong><br />

b<strong>and</strong>27,53 led by a large moustachioed<br />

bass player. 8 And <strong>the</strong>re stood <strong>the</strong><br />

vicar, vestments blow<strong>in</strong>g <strong>in</strong> <strong>the</strong><br />

w<strong>in</strong>d, his Stratocaster pound<strong>in</strong>g out<br />

<strong>the</strong> chords. 50<br />

‘The groom should be along any<br />

moment’, someone hoped. There he<br />

is at <strong>the</strong> edge <strong>of</strong> <strong>the</strong> volcano crater.<br />

‘It looks as if he’s iron<strong>in</strong>g his<br />

shirt‘, 25 said Alice. ‘He must be very<br />

proud <strong>of</strong> his appearance.’<br />

‘It’s gett<strong>in</strong>g hot’, she thought as<br />

she went up to a build<strong>in</strong>g next to <strong>the</strong><br />

church. ‘It’s like a sauna!’ Steam was<br />

com<strong>in</strong>g out, <strong>and</strong> she peeped <strong>in</strong>side.<br />

A sweat<strong>in</strong>g woman was balanc<strong>in</strong>g<br />

on her head. 4,61 ‘Golly’, thought<br />

Alice. ‘That’s <strong>the</strong> yoga Sirsha Asana<br />

position. 4 I could never master that.‘<br />

‘Never m<strong>in</strong>d’, said <strong>the</strong> <strong>in</strong>verted<br />

practitioner. ‘You can always go<br />

home <strong>and</strong> practice Thulaikatchi*<br />

Asana.’<br />

A buzz turned her attention<br />

skywards. Were <strong>the</strong>y model aircraft<br />

close to, 38,46 or real ones48,63 far away?<br />

▼<br />

SCOPE | SEPTEMBER 2012 | 15


▼<br />

Some <strong>of</strong> <strong>the</strong> models were almost life<br />

size, 38 so it was hard to tell. But one<br />

was trail<strong>in</strong>g a long banner; <strong>the</strong><br />

writ<strong>in</strong>g too small to read.<br />

Just <strong>the</strong>n <strong>the</strong> volcano started<br />

rumbl<strong>in</strong>g, <strong>and</strong> great plumes <strong>of</strong><br />

smoke billowed skywards. Panic set<br />

<strong>in</strong>; everyone started runn<strong>in</strong>g down<br />

<strong>the</strong> mounta<strong>in</strong>. Great folds <strong>of</strong> lava,<br />

red hot, <strong>and</strong> sulphurous fumes<br />

chas<strong>in</strong>g <strong>the</strong>m.<br />

Alice could feel <strong>the</strong> lava lapp<strong>in</strong>g<br />

at her feet, her lungs were burst<strong>in</strong>g,<br />

<strong>the</strong> smoke envelop<strong>in</strong>g her. Just <strong>in</strong><br />

time, without a second to spare, <strong>the</strong><br />

plane with <strong>the</strong> banner swooped<br />

down low on Alice. A drown<strong>in</strong>g man<br />

REFERENCES<br />

1 Havercr<strong>of</strong>t, Klevenhagen.<br />

Phys Med Biol 1993; 38:<br />

25–38.<br />

2 Anon<br />

3 Adrian Lonsdale<br />

4 Agelos Saplaouros<br />

5 Alexis Moore<br />

6 Alison Scott<br />

7 Andrew Tyler<br />

8 Andy Beavis<br />

9 Andy Buckle<br />

10 Angela Cotton<br />

11 Angela New<strong>in</strong>g<br />

12 Arek Mazurek<br />

13 Bruce Walmsley<br />

16 | SEPTEMBER 2012 | SCOPE<br />

will grasp at a straw, <strong>and</strong> a tra<strong>in</strong>ee<br />

cl<strong>in</strong>ical scientist will do <strong>the</strong> same to<br />

a banner trail<strong>in</strong>g from a model<br />

aircraft when be<strong>in</strong>g chased down a<br />

mounta<strong>in</strong> by a stream <strong>of</strong> boil<strong>in</strong>g<br />

lava.<br />

‘Lucky I learned how to climb<br />

silks 34,36 when I was at juggl<strong>in</strong>g 27,52,72<br />

school’, thought Alice, as she<br />

performed her favourite double<br />

hocks climb. It was when she was<br />

safely near <strong>the</strong> top that she paused<br />

<strong>and</strong> looked down at <strong>the</strong> writ<strong>in</strong>g on<br />

<strong>the</strong> banner. It was Havercr<strong>of</strong>t’s<br />

paper on ion recomb<strong>in</strong>ation, <strong>the</strong><br />

very one she had been look<strong>in</strong>g for!<br />

Engrossed by <strong>the</strong> elegance <strong>of</strong><br />

14 Carol<strong>in</strong>e Rudl<strong>and</strong> (May)<br />

15 Carolyn Richardson<br />

16 Ca<strong>the</strong>r<strong>in</strong>e Eveleigh<br />

17 Clare Hadley<br />

18 Conor Heeney<br />

19 David Carpenter<br />

20 David Taylor<br />

21 Ed Hockaday<br />

22 Elizabeth Crawford<br />

23 Eve Sh<strong>in</strong><br />

24 Giles David Morrison<br />

25 Graham Freestone<br />

26 Hea<strong>the</strong>r Williams<br />

27 Henry Lawrence<br />

28 Ian Negus<br />

29 Jack Aylward<br />

30 Jacquel<strong>in</strong>e Roberts<br />

31 James Goracy<br />

32 James Weston<br />

33 Janet Droege (née<br />

Havercr<strong>of</strong>t)<br />

34 Jason Cashmore<br />

35 Joseph O'Brien<br />

36 Karen Chalmers<br />

37 Karen Fuller<br />

38 Keith Mitchell<br />

39 Lucy W<strong>in</strong>ch<br />

40 Lynn Mart<strong>in</strong>ez<br />

41 Lynsey Hamlett<br />

42 Maria Holstensson<br />

FIGURE 4.<br />

‘Lucky I learned<br />

how to climb silks<br />

when I was at<br />

juggl<strong>in</strong>g school.’<br />

▼<br />

*‘Thulaikatchi’ is<br />

Tamil for<br />

‘television’.<br />

Talekatchi Asana is<br />

sitt<strong>in</strong>g <strong>in</strong> front <strong>of</strong><br />

<strong>the</strong> telly.<br />

43 Mar<strong>in</strong>a Romanchikova<br />

44 Mark Powell<br />

45 Mark Rawson<br />

46 Ma<strong>the</strong>w James<br />

47 Matilda Nyekiova<br />

48 Mike Avison<br />

49 Neil S. Rob<strong>in</strong>son<br />

50 Paul Ganney<br />

51 Peter Cl<strong>in</strong>ch<br />

52 Peter Julyan<br />

53 Philip Orr<br />

54 Rachel Cooke<br />

55 Robert Fl<strong>in</strong>tham<br />

56 Robert Speller<br />

57 Rob<strong>in</strong> Laney<br />

Havercr<strong>of</strong>t’s analysis, she read on.<br />

Soon she had quite forgotten her<br />

plight, be<strong>in</strong>g towed beh<strong>in</strong>d a giant<br />

model aircraft escap<strong>in</strong>g from an<br />

explod<strong>in</strong>g volcano. And when she<br />

had f<strong>in</strong>ished <strong>the</strong> conclusion she<br />

looked up. Like a magic trick 44 she<br />

had recomb<strong>in</strong>ed with reality! She<br />

was back <strong>in</strong> her <strong>of</strong>fice at Lymeswold<br />

Hospital, surrounded by a pile <strong>of</strong><br />

debris from <strong>the</strong> archive cupboard.<br />

‘Golly, what an adventure!’,<br />

thought Alice. ‘If I wrote it up, noone<br />

would believe me. 2,27,47 I can’t<br />

wait until I f<strong>in</strong>ish my portfolio <strong>and</strong><br />

meet up with some normal people<br />

aga<strong>in</strong>.’ n<br />

58 Rosal<strong>in</strong>d Perr<strong>in</strong><br />

59 Rosemary Morton<br />

60 Ryan Lewis<br />

61 Samantha Eustace<br />

62 Sarah Naylor<br />

63 Sean Owen<br />

64 Sharan Packer<br />

65 Stephanie Wentworth<br />

66 Stephen Mason<br />

67 Steve Weston<br />

68 Teresa Clark<br />

69 Tom Jordan<br />

70 Usman Lula<br />

71 Wayne Gardner<br />

72 Yatigammana Dylan


Radiat<strong>in</strong>g enthusiasm: IPEM at<br />

<strong>the</strong> 2012 Big Bang Science Fair<br />

Lisa Parker-Gomm (External Relations Manager, IPEM)<br />

How do you expla<strong>in</strong><br />

radioactivity to a 6-yearold?<br />

This was just one <strong>of</strong><br />

<strong>the</strong> challenges IPEM’s<br />

team <strong>of</strong> outreach<br />

volunteers set<br />

<strong>the</strong>mselves at this year’s Big Bang Fair<br />

– a national event for young people<br />

which celebrates science, technology,<br />

eng<strong>in</strong>eer<strong>in</strong>g <strong>and</strong> maths.<br />

In March over 56,000 visitors<br />

flocked to <strong>the</strong> NEC <strong>in</strong> Birm<strong>in</strong>gham <strong>and</strong><br />

hundreds <strong>of</strong> <strong>the</strong>m visited IPEM’s st<strong>and</strong><br />

where <strong>the</strong>y had h<strong>and</strong>s-on experience <strong>of</strong><br />

how physics is used <strong>in</strong> healthcare. Matt<br />

Dunn, Head <strong>of</strong> Radiology <strong>Physics</strong> at<br />

Nott<strong>in</strong>gham University Hospitals NHS<br />

Trust, led <strong>the</strong> IPEM team: ‘Our st<strong>and</strong><br />

seemed relatively low-budget – no<br />

expensive plasma screens <strong>and</strong> suchlike.<br />

But our real strength was <strong>in</strong> allow<strong>in</strong>g<br />

<strong>the</strong> visitors to get <strong>the</strong>ir h<strong>and</strong>s on real<br />

equipment that is actually used <strong>in</strong><br />

hospitals. Hundreds <strong>of</strong> people came to<br />

our st<strong>and</strong>, <strong>and</strong> we were busy most <strong>of</strong><br />

<strong>the</strong> time’.<br />

DISCOVERING RADIOACTIVITY<br />

IPEM’s most attention-grabb<strong>in</strong>g<br />

<strong>of</strong>fer<strong>in</strong>g was a simulated hospital<br />

radioactivity <strong>in</strong>cident. Every 30<br />

m<strong>in</strong>utes <strong>the</strong> alarms went <strong>of</strong>f <strong>and</strong> it was<br />

time to don <strong>the</strong> big yellow CBRN<br />

protection suit, apron, gloves,<br />

overshoes, hat <strong>and</strong> o<strong>the</strong>r pretend<br />

‘protection’ gear <strong>and</strong> start search<strong>in</strong>g for<br />

radiation! No-one was <strong>in</strong> danger, <strong>of</strong><br />

course, but it gave visitors <strong>the</strong><br />

opportunity to scan unfortunate<br />

victims with a Geiger counter to f<strong>in</strong>d<br />

‘radiation’ (it was just alcohol vapour),<br />

<strong>and</strong> also to discover how everyday<br />

items such as bananas <strong>and</strong> potassium<br />

salt (Lo-Salt) are radioactive too. As<br />

well as be<strong>in</strong>g fun, <strong>the</strong> demonstrators<br />

had <strong>the</strong> opportunity to expla<strong>in</strong> <strong>the</strong><br />

many ways radiation is used <strong>in</strong><br />

medic<strong>in</strong>e for <strong>the</strong> benefit <strong>of</strong> patients.<br />

One parent asked a volunteer to<br />

expla<strong>in</strong> radioactivity to his 6-year-old<br />

daughter. Amaz<strong>in</strong>gly, <strong>the</strong> child claimed<br />

to know what atoms were, <strong>and</strong> <strong>the</strong>y<br />

were both happy with <strong>the</strong> impromptu,<br />

if perhaps non-PC, explanation that<br />

some atoms didn’t like <strong>the</strong> way <strong>the</strong>y<br />

looked, so <strong>the</strong>y threw <strong>of</strong>f bits <strong>of</strong><br />

<strong>the</strong>mselves until <strong>the</strong>y felt better!<br />

Ano<strong>the</strong>r activity on <strong>of</strong>fer was us<strong>in</strong>g<br />

an ultrasound scanner to identify<br />

sweets <strong>and</strong> fruit concealed <strong>in</strong> m<strong>in</strong>iphantoms.<br />

‘The children enjoyed <strong>the</strong><br />

game, <strong>and</strong> on a few occasions we<br />

scanned ourselves to show <strong>the</strong> very<br />

enthusiastic ones our kidneys, hearts<br />

<strong>and</strong> blood vessel <strong>in</strong> our wrists’,<br />

commented Matt Dunn. This proved<br />

to be a very engag<strong>in</strong>g demonstration<br />

when families would be guess<strong>in</strong>g <strong>the</strong><br />

fruit toge<strong>the</strong>r, <strong>and</strong> parents tell<strong>in</strong>g <strong>the</strong>ir<br />

children about <strong>the</strong>ir experience with<br />

ultrasound dur<strong>in</strong>g pregnancy.<br />

IPEM’s third <strong>of</strong>fer<strong>in</strong>g was blood<br />

pressure <strong>and</strong> pulse monitor<strong>in</strong>g. ‘My<br />

read<strong>in</strong>gs were sky high at <strong>the</strong> start<br />

due to <strong>the</strong> stress <strong>of</strong> organis<strong>in</strong>g <strong>the</strong><br />

event!’, said Matt Dunn. ‘We were a<br />

bit worried too <strong>in</strong> case some <strong>of</strong> <strong>the</strong><br />

visitors’ read<strong>in</strong>gs fell outside <strong>the</strong><br />

normal range, but fortunately that<br />

didn’t happen.’ Children approached<br />

<strong>the</strong> experience with anxiety, much<br />

giggl<strong>in</strong>g <strong>and</strong> a spirit <strong>of</strong> competition to<br />

see who had <strong>the</strong> best read<strong>in</strong>g.<br />

Volunteers agreed that although it<br />

could be tir<strong>in</strong>g to st<strong>and</strong> all day talk<strong>in</strong>g<br />

to people, when <strong>the</strong>y found someone<br />

who was genu<strong>in</strong>ely <strong>in</strong>terested <strong>in</strong> what<br />

<strong>the</strong>y were say<strong>in</strong>g it was a real joy. Matt<br />

said: ‘Many <strong>of</strong> <strong>the</strong> kids were really<br />

enthusiastic about science <strong>and</strong> it was<br />

really good to see that. We weren’t<br />

really try<strong>in</strong>g to recruit <strong>the</strong>m to be<br />

medical physicists, but just try<strong>in</strong>g to<br />

<strong>in</strong>spire <strong>the</strong>m to carry on <strong>the</strong>ir science<br />

education so that hopefully <strong>in</strong> years to<br />

come <strong>the</strong>re will be a better supply <strong>of</strong><br />

scientists contribut<strong>in</strong>g to <strong>the</strong> UK<br />

economy <strong>and</strong> society <strong>in</strong> general.’ Part<br />

II tra<strong>in</strong>ee Kirsty Hodgson commented:<br />

‘It was great to talk to so many<br />

<strong>in</strong>terest<strong>in</strong>g people, not only <strong>the</strong><br />

children <strong>and</strong> teachers, but members <strong>of</strong><br />

<strong>the</strong> Science Council, <strong>the</strong> STEM<br />

ambassador scheme <strong>and</strong> many o<strong>the</strong>rs.<br />

It will be a good experience to put <strong>in</strong>to<br />

my portfolio <strong>and</strong> it was nice to<br />

promote physics <strong>in</strong> healthcare as<br />

many people had not come across it<br />

before.’<br />

BENEFITS OF VOLUNTEERING<br />

The Big Bang Fair is delivered by over<br />

170 organisations from <strong>the</strong> public,<br />

private <strong>and</strong> voluntary sectors. Led by<br />

▼ Scann<strong>in</strong>g<br />

victims to<br />

detect<br />

‘radiation’.<br />

FEATURE | SCOPE<br />

<strong>Eng<strong>in</strong>eer<strong>in</strong>g</strong>UK <strong>in</strong> partnership with<br />

<strong>the</strong> British Science Association, <strong>the</strong><br />

<strong>Institute</strong> <strong>of</strong> <strong>Physics</strong>, <strong>the</strong> Science<br />

Council, <strong>the</strong> Royal Academy <strong>of</strong><br />

<strong>Eng<strong>in</strong>eer<strong>in</strong>g</strong> <strong>and</strong> Young Eng<strong>in</strong>eers, <strong>the</strong><br />

event is supported by <strong>the</strong> Department<br />

for Bus<strong>in</strong>ess, Innovation <strong>and</strong> Skills as<br />

well as numerous sponsors from<br />

<strong>in</strong>dustry. IPEM has taken part <strong>in</strong> each<br />

<strong>of</strong> <strong>the</strong> 4 years <strong>the</strong> event has been<br />

staged. For more <strong>in</strong>formation see:<br />

www.<strong>the</strong>bigbangfair.co.uk.<br />

Next year’s national event will be<br />

<strong>in</strong> London on 24th–26th March <strong>and</strong><br />

IPEM will once aga<strong>in</strong> be tak<strong>in</strong>g part. If<br />

you’re passionate about your<br />

pr<strong>of</strong>ession <strong>and</strong> want to share this with<br />

young people, why not give it a go?<br />

IPEM has a range <strong>of</strong> pre-prepared<br />

activities, support<strong>in</strong>g materials for<br />

teachers, <strong>and</strong> will deal with all <strong>the</strong><br />

logistics – all we need is a little <strong>of</strong><br />

your time <strong>and</strong> enthusiasm. To f<strong>in</strong>d out<br />

more, contact outreach@ipem.ac.uk.<br />

As Evelyn Sh<strong>in</strong>, ano<strong>the</strong>r volunteer<br />

from Nott<strong>in</strong>gham University<br />

Hospitals, enthused: ‘If <strong>of</strong>fered aga<strong>in</strong>,<br />

I’d volunteer <strong>in</strong> a heartbeat. It was a<br />

really great experience.’ n<br />

ACKNOWLEDGEMENTS<br />

Thanks to <strong>the</strong> follow<strong>in</strong>g for <strong>the</strong>ir contribution<br />

to this report: Mat<strong>the</strong>w Dunn, Head <strong>of</strong><br />

Radiology <strong>Physics</strong>, Nott<strong>in</strong>gham University<br />

Hospitals NHS Trust; Evelyn Sh<strong>in</strong>, Nott<strong>in</strong>gham<br />

University Hospitals NHS Trust; Kirsty<br />

Hodgson, University Hospitals Birm<strong>in</strong>gham<br />

NHS Foundation Trust; Eva McClean,<br />

Development <strong>and</strong> Communications Manager,<br />

IPEM, <strong>and</strong> to all <strong>the</strong> o<strong>the</strong>r volunteers who<br />

helped on <strong>the</strong> st<strong>and</strong> or loaned equipment for<br />

<strong>the</strong> demonstrations.<br />

SCOPE | SEPTEMBER 2012 | 17


SCOPE | FEATURE<br />

The launch <strong>of</strong> IPEM outreach<br />

strategy to connect with students<br />

Mat<strong>the</strong>w Dunn (Nott<strong>in</strong>gham University Hospitals NHS Trust)<br />

The new IPEM outreach<br />

strategy was recently<br />

launched at <strong>the</strong><br />

communicat<strong>in</strong>g<br />

science session at<br />

MPEC 2012 <strong>in</strong> Oxford.<br />

The outreach strategy aims to help<br />

members communicate science <strong>and</strong><br />

eng<strong>in</strong>eer<strong>in</strong>g to students to encourage<br />

<strong>the</strong>m to study <strong>the</strong>se subjects fur<strong>the</strong>r.<br />

It is vital that students underst<strong>and</strong><br />

<strong>the</strong> excitement <strong>and</strong> importance <strong>of</strong><br />

science, technology <strong>and</strong> eng<strong>in</strong>eer<strong>in</strong>g<br />

<strong>in</strong> medic<strong>in</strong>e. The NHS alone is by far<br />

<strong>the</strong> largest employer <strong>of</strong> scientists <strong>in</strong><br />

<strong>the</strong> UK yet students are <strong>of</strong>ten<br />

unaware <strong>of</strong> <strong>the</strong> career opportunities<br />

<strong>in</strong> healthcare science <strong>and</strong><br />

eng<strong>in</strong>eer<strong>in</strong>g. The types <strong>of</strong> events that<br />

members currently support is widerang<strong>in</strong>g.<br />

Examples <strong>in</strong>clude:<br />

n school careers fairs,<br />

n classroom experiments <strong>and</strong><br />

demonstrations,<br />

n hospital open days,<br />

n departmental visits or tours,<br />

n teacher-focussed events.<br />

IPEM <strong>and</strong> <strong>the</strong> membership have<br />

supported 35 such events throughout<br />

2011 <strong>and</strong> 2012.<br />

Every event has a different<br />

audience so it is important that <strong>the</strong><br />

right type <strong>of</strong> activity is matched to<br />

<strong>the</strong> event <strong>in</strong> order to maximise<br />

impact. The purpose is to encourage<br />

<strong>the</strong> study <strong>of</strong> general science GCSE<br />

<strong>and</strong> A-level subjects <strong>and</strong> to <strong>in</strong>troduce<br />

<strong>the</strong> concept <strong>of</strong> scientists <strong>and</strong><br />

eng<strong>in</strong>eers work<strong>in</strong>g <strong>in</strong> medic<strong>in</strong>e.<br />

Students are generally surprised to<br />

learn that physics <strong>and</strong> eng<strong>in</strong>eer<strong>in</strong>g<br />

degrees can lead to jobs <strong>in</strong> <strong>the</strong><br />

medical <strong>in</strong>dustry <strong>and</strong> healthcare.<br />

IPEM’S OUTREACH ACTIVITIES<br />

IPEM’s outreach activities have<br />

traditionally been delivered <strong>and</strong><br />

supported by <strong>in</strong>dividual members on<br />

a local level, <strong>of</strong>ten <strong>in</strong> <strong>the</strong>ir own time.<br />

As a result efforts were <strong>of</strong>ten<br />

duplicated <strong>and</strong> experiences not<br />

shared. The impact was sometimes<br />

limited as <strong>the</strong> activities were not<br />

always targeted at <strong>the</strong> appropriate<br />

18 | SEPTEMBER 2012 | SCOPE<br />

Work<strong>in</strong>g with<br />

school children to<br />

stimulate <strong>the</strong>ir<br />

<strong>in</strong>terest can be<br />

hugely reward<strong>in</strong>g.<br />

▼<br />

“<br />

The<br />

types <strong>of</strong><br />

events that<br />

members<br />

currently<br />

support is<br />

widerang<strong>in</strong>g<br />

”<br />

group <strong>and</strong> were costly <strong>in</strong> terms <strong>of</strong><br />

time to develop <strong>and</strong> adm<strong>in</strong>ister. In<br />

<strong>the</strong> last few years more <strong>of</strong>fice support<br />

has been requested by members <strong>and</strong><br />

<strong>the</strong> result<strong>in</strong>g <strong>in</strong>crease <strong>in</strong> outreach<br />

activities requires a more strategic<br />

approach to IPEM’s outreach efforts.<br />

IPEM Council has allocated fund<strong>in</strong>g<br />

to deliver this strategy over 2 years.<br />

IPEM will also cont<strong>in</strong>ue to directly<br />

support a limited number <strong>of</strong> events<br />

such as <strong>the</strong> national Big Bang Fair<br />

(www.<strong>the</strong>bigbangfair.co.uk, see<br />

page 17).<br />

The vast majority <strong>of</strong> outreach<br />

activity is best delivered by volunteer<br />

IPEM members; however, <strong>the</strong> effort<br />

<strong>in</strong>volved <strong>in</strong> deliver<strong>in</strong>g outreach<br />

activities can be substantially<br />

reduced by hav<strong>in</strong>g a range <strong>of</strong> ‘readymade’<br />

activities <strong>and</strong> resources which<br />

can be downloaded from <strong>the</strong> website<br />

or sent out to members from <strong>the</strong><br />

<strong>of</strong>fice. When developed <strong>the</strong>se<br />

materials will allow members to<br />

concentrate on <strong>the</strong> delivery <strong>of</strong><br />

outreach.<br />

IPEM members at all stages <strong>of</strong><br />

<strong>the</strong>ir careers are encouraged to<br />

support <strong>the</strong> <strong>in</strong>itiative <strong>and</strong> get<br />

<strong>in</strong>volved <strong>in</strong> outreach activities from<br />

talk<strong>in</strong>g to students to develop<strong>in</strong>g<br />

activities or experiments. Although<br />

work<strong>in</strong>g with school children may<br />

<strong>in</strong>itially be daunt<strong>in</strong>g, most members<br />

f<strong>in</strong>d <strong>the</strong> experience hugely reward<strong>in</strong>g<br />

<strong>and</strong> also a great way <strong>of</strong> improv<strong>in</strong>g<br />

communication skills. n<br />

GET INVOLVED<br />

To f<strong>in</strong>d out more or volunteer please<br />

contact <strong>the</strong> outreach team:<br />

outreach@ipem.ac.uk


2011 AAPM–IPEM MEDICAL PHYSICS<br />

TRAVEL GRANT REPORT<br />

JUN DENG Yale New Haven Hospital, New Haven, CT, USA<br />

I<br />

n April 2012 I visited <strong>the</strong> UK<br />

after receiv<strong>in</strong>g an<br />

AAPM–IPEM Medical<br />

<strong>Physics</strong> Travel Grant. Here I<br />

outl<strong>in</strong>e my experiences at<br />

each <strong>of</strong> <strong>the</strong> centres that I went<br />

to <strong>and</strong> <strong>the</strong> people that I met.<br />

16TH APRIL: CASTLE<br />

HILL HOSPITAL<br />

After a long tra<strong>in</strong> ride from London to<br />

Hull, I f<strong>in</strong>ally arrived at <strong>the</strong> Castle<br />

Hill Hospital where Dr Andy Beavis,<br />

Head <strong>of</strong> <strong>the</strong> Radiation <strong>Physics</strong><br />

Department, was <strong>the</strong> host for my first<br />

stop dur<strong>in</strong>g this trip to <strong>the</strong> UK. My<br />

visit started with a tour <strong>of</strong> <strong>the</strong><br />

department led by Dr Beavis. The<br />

whole oncology centre is very new<br />

with eco- <strong>and</strong> patient-friendly designs<br />

everywhere, which to me makes it<br />

seem ra<strong>the</strong>r more like a hotel than a<br />

cancer centre for radio<strong>the</strong>rapy. Then I<br />

gave a lecture talk<strong>in</strong>g about <strong>the</strong><br />

kVCBCT imag<strong>in</strong>g doses <strong>and</strong> <strong>the</strong><br />

associated cancer risks, after which<br />

we had a round-table meet<strong>in</strong>g for<br />

physics staff so that everyone could<br />

get <strong>in</strong>volved <strong>in</strong> a more <strong>in</strong>teractive<br />

discussion. The primary concerns<br />

were about <strong>the</strong> imag<strong>in</strong>g doses <strong>and</strong><br />

why CT manufacturers did a better<br />

job than <strong>the</strong> l<strong>in</strong>ac manufacturers for<br />

CBCT <strong>in</strong> terms <strong>of</strong> imag<strong>in</strong>g dose<br />

reduction, protocol optimisation <strong>and</strong><br />

patient safety. I also learnt that a<br />

virtual CT reconstructor has been<br />

developed by this group so that<br />

virtual CT scans can be simulated to<br />

study <strong>the</strong> correlation between <strong>the</strong><br />

imag<strong>in</strong>g doses <strong>and</strong> <strong>the</strong> image quality<br />

without actually perform<strong>in</strong>g a scan<br />

on a patient. I was very <strong>in</strong>terested <strong>in</strong><br />

this project <strong>and</strong> <strong>in</strong>dicated that our<br />

group was develop<strong>in</strong>g a similar tool<br />

dedicated to CBCT virtual simulation<br />

<strong>and</strong> reconstruction. F<strong>in</strong>ally, I was<br />

lucky enough to experience a state-<strong>of</strong><strong>the</strong>-art<br />

technology named VERT<br />

developed <strong>and</strong> co-founded by Dr<br />

Beavis. VERT (virtual environment<br />

for radio<strong>the</strong>rapy <strong>and</strong> tra<strong>in</strong><strong>in</strong>g) is a<br />

l<strong>in</strong>ac simulator set <strong>in</strong> a 3D virtual<br />

environment, which can help users<br />

tra<strong>in</strong> with full access to <strong>the</strong> l<strong>in</strong>ac<br />

functionality without <strong>in</strong>terfer<strong>in</strong>g with<br />

<strong>the</strong> cl<strong>in</strong>ical workflow. We actually<br />

took a picture as shown <strong>in</strong> figure 1<br />

with VERT displayed <strong>in</strong> <strong>the</strong><br />

background.<br />

FIGURE 1.<br />

Dr Andy Beavis<br />

<strong>and</strong> Jun at<br />

Castle Hill<br />

Hospital.<br />

▼<br />

TRAVEL AWARD | SCOPE<br />

17TH APRIL: CLATTERBRIDGE<br />

CENTRE FOR ONCOLOGY<br />

The follow<strong>in</strong>g day I visited <strong>the</strong><br />

Clatterbridge Centre for Oncology<br />

where Dr Alan Nahum was my<br />

host. We actually started our<br />

conversion with our fond memories<br />

<strong>of</strong> <strong>the</strong> past. I was fasc<strong>in</strong>ated by all<br />

sorts <strong>of</strong> legendary stories told by<br />

Alan about our common friends.<br />

Alan’s postdoc Dr Julien Uzan gave<br />

me a brief <strong>in</strong>troduction to <strong>the</strong>ir latest<br />

research tool called Biosuite, aim<strong>in</strong>g<br />

to facilitate biologically based<br />

treatment plann<strong>in</strong>g <strong>and</strong><br />

optimisation. The s<strong>of</strong>tware analysed<br />

<strong>the</strong> DVH data exported from<br />

conventional treatment plann<strong>in</strong>g<br />

systems <strong>and</strong> computed TCP <strong>and</strong><br />

NTCP based on published Marsden<br />

<strong>and</strong> LKB models. In addition, <strong>the</strong><br />

s<strong>of</strong>tware was able to optimise <strong>the</strong><br />

plan with a fixed NTCP value, <strong>the</strong><br />

so-called isotoxic plann<strong>in</strong>g scheme,<br />

<strong>and</strong> generate a series <strong>of</strong> plans with<br />

different TCP values correspond<strong>in</strong>g<br />

to different fractionations. Later on,<br />

I gave a lecture on kVCBCT <strong>and</strong> was<br />

engaged <strong>in</strong> a very <strong>in</strong>teractive<br />

discussion with dozens <strong>of</strong> physicists<br />

<strong>and</strong> research staff. I enjoyed some<br />

tough questions raised by Alan <strong>and</strong><br />

Dr Ge<strong>of</strong>f Lawrence. F<strong>in</strong>ally, I was<br />

k<strong>in</strong>dly given a tour <strong>of</strong> <strong>the</strong> only<br />

proton radio<strong>the</strong>rapy facility <strong>in</strong> <strong>the</strong><br />

UK, Douglas Cyclotron (figure 2), by<br />

Dr Andrzej Kacperek. It produced a<br />

s<strong>in</strong>gle energy <strong>of</strong> 62 MeV proton<br />

beams dedicated to radio<strong>the</strong>rapy <strong>of</strong><br />

eye tumours due to its limited<br />

treatment depth <strong>in</strong> tissue <strong>of</strong> 3 cm.<br />

The highly acclaimed<br />

pr<strong>of</strong>essionalism <strong>and</strong> rigorous efforts<br />

to quality control <strong>the</strong> cl<strong>in</strong>ical<br />

practices at every step made it a<br />

highly successful facility, which<br />

treated one-third <strong>of</strong> eye patients <strong>in</strong><br />

<strong>the</strong> UK <strong>and</strong> dozens <strong>of</strong> patients<br />

across <strong>the</strong> world. It was a busy day<br />

for me. In fact, I was so <strong>in</strong>volved<br />

with <strong>the</strong> <strong>in</strong>tensive discussions that I<br />

forgot my room number when I got<br />

back to my hotel. Luckily I did not<br />

forget which hotel I was stay<strong>in</strong>g <strong>in</strong>!<br />

▼<br />

SCOPE | SEPTEMBER 2012 | 19


▼<br />

SCOPE | TRAVEL AWARD<br />

20 | SEPTEMBER 2012 | SCOPE<br />

FIGURE 2.<br />

Dr Andrzej<br />

Kacperek, Dr<br />

Alan Nahum <strong>and</strong><br />

Jun at<br />

Clatterbridge<br />

Centre for<br />

Oncology.<br />

▼<br />

FIGURE 3.<br />

Dr Jonathan<br />

Sykes, Dr Vivian<br />

Consgrove <strong>and</strong><br />

Jun at St James's<br />

<strong>Institute</strong> for<br />

Oncology.<br />

▼<br />

FIGURE 4.<br />

Jun, Dr Jim<br />

Warr<strong>in</strong>gton, Dr<br />

Margaret<br />

Bidmead, Dr<br />

Ellen Donovan<br />

<strong>and</strong> Dr Phil Evans<br />

at Royal Marsden<br />

Hospital.<br />

▼<br />

FIGURE 5.<br />

Dr Elizabeth<br />

Macaulay <strong>and</strong><br />

Jun at Churchill<br />

Hospital.<br />

▼<br />

18TH APRIL: ST JAMES’S<br />

INSTITUTE FOR ONCOLOGY<br />

My third visit took place at St James’s<br />

<strong>Institute</strong> for Oncology <strong>in</strong> Leeds where<br />

Dr Vivian Consgrove, Head <strong>of</strong><br />

Radio<strong>the</strong>rapy <strong>Physics</strong>, was my host<br />

(figure 3). The centre has ten <strong>Elekta</strong><br />

l<strong>in</strong>acs for cl<strong>in</strong>ical treatments <strong>and</strong> two<br />

for research. With about 6,500 patients<br />

treated annually, it is quite a challenge<br />

to manage <strong>the</strong> whole cl<strong>in</strong>ical workflow<br />

seamlessly without errors. I noticed<br />

three major factors contribut<strong>in</strong>g to <strong>the</strong>ir<br />

high efficiency: (1) a well thought-out<br />

design <strong>of</strong> <strong>the</strong> cl<strong>in</strong>ic such that patients<br />

received pr<strong>of</strong>essional care from a<br />

dedicated group <strong>of</strong> cl<strong>in</strong>icians while<br />

ma<strong>in</strong>ta<strong>in</strong><strong>in</strong>g a high degree <strong>of</strong> privacy;<br />

(2) a clear structure <strong>of</strong> management <strong>and</strong><br />

easy-to-follow guidel<strong>in</strong>es <strong>and</strong> policies,<br />

<strong>and</strong> (3) all <strong>the</strong> photon beams are<br />

matched throughout <strong>the</strong> department.<br />

Later on, I gave a lecture on imag<strong>in</strong>g<br />

doses from kVCBCT <strong>and</strong> <strong>the</strong>ir<br />

associated cancer risks. Although my<br />

study <strong>in</strong>dicated large imag<strong>in</strong>g doses<br />

from CBCT procedures, I emphasised<br />

more than once that people should not<br />

be scared by <strong>the</strong> potential cancer risks<br />

associated with <strong>the</strong> medical imag<strong>in</strong>g<br />

procedures as long as those procedures<br />

are adm<strong>in</strong>istrated <strong>in</strong> a prudent way <strong>and</strong><br />

are cl<strong>in</strong>ically justified. The risk <strong>of</strong> not<br />

hav<strong>in</strong>g those procedures done would<br />

be much greater for most <strong>of</strong> <strong>the</strong> cancer<br />

patients. Dr Jonathan Sykes, one <strong>of</strong> <strong>the</strong><br />

physicists do<strong>in</strong>g research work on IGRT<br />

<strong>and</strong> kVCBCT, exchanged his ideas with<br />

me on how to correlate CBCT with CT<br />

as plann<strong>in</strong>g CT has always been<br />

considered as reference to <strong>the</strong> CBCT<br />

images <strong>in</strong> determ<strong>in</strong><strong>in</strong>g <strong>the</strong> shifts. I<br />

po<strong>in</strong>ted out that ano<strong>the</strong>r possible<br />

approach would be to use onl<strong>in</strong>e CBCT<br />

image datasets as <strong>the</strong> reference <strong>in</strong>stead<br />

<strong>of</strong> plann<strong>in</strong>g CT as long as <strong>the</strong><br />

Hounsfield number <strong>in</strong> CBCT images is<br />

accurately determ<strong>in</strong>ed.<br />

19TH APRIL: ROYAL<br />

MARSDEN HOSPITAL<br />

I visited Royal Marsden Hospital<br />

(RMH) <strong>in</strong> Sutton <strong>the</strong> next day. My host<br />

was Dr Phil Evans, Head <strong>of</strong> <strong>the</strong><br />

Radiation <strong>Physics</strong> Department, who<br />

gave me a detailed <strong>in</strong>troduction to <strong>the</strong><br />

organisation <strong>of</strong> RMH (figure 4). He<br />

showed me a copy <strong>of</strong> <strong>the</strong> RMH’s 2010<br />

annual report <strong>and</strong> discussed some <strong>of</strong><br />

<strong>the</strong> fasc<strong>in</strong>at<strong>in</strong>g projects that were<br />

conducted dur<strong>in</strong>g 2010. I delivered my<br />

oral presentation to a large audience<br />

<strong>in</strong>clud<strong>in</strong>g <strong>the</strong> staff members from <strong>the</strong><br />

Chelsea site. My lecture generated quite<br />

a few questions regard<strong>in</strong>g <strong>the</strong> CBCT


applications <strong>in</strong> <strong>the</strong> cl<strong>in</strong>ic. I also<br />

emphasised <strong>in</strong> my talk that prudent<br />

medical imag<strong>in</strong>g procedures always<br />

outweighed <strong>the</strong> potential cancer risks,<br />

because miss<strong>in</strong>g <strong>the</strong> tumour target<br />

would lead to greater cancer risks <strong>in</strong><br />

<strong>the</strong> future if necessary medical imag<strong>in</strong>g<br />

procedures were not performed. Later<br />

on I had <strong>the</strong> opportunity to have a oneon-one<br />

discussion with some <strong>of</strong> <strong>the</strong><br />

research fellows, postdocs <strong>and</strong> PhD<br />

students at RMH. The topics were very<br />

<strong>in</strong>terest<strong>in</strong>g <strong>and</strong> significant, cover<strong>in</strong>g<br />

imag<strong>in</strong>g dose, toxicity <strong>and</strong> marg<strong>in</strong><br />

reduction correlations <strong>in</strong> breast cancer<br />

radio<strong>the</strong>rapy with CBCT, patient<br />

fatigue study <strong>in</strong> IMRT treatments <strong>of</strong><br />

head <strong>and</strong> neck cancer, a CT x-ray<br />

energy spectrum simulator, breast<br />

tissue segmentation for better <strong>and</strong><br />

more accurate contour<strong>in</strong>g <strong>and</strong> dose<br />

pa<strong>in</strong>t<strong>in</strong>g, dynamic leaf track<strong>in</strong>g for<br />

<strong>Elekta</strong> MLC, as well as a new CMOS<br />

technology developed to replace<br />

current EPID for better <strong>and</strong> quicker<br />

responses to high-dose radiation. I had<br />

a pleasant <strong>and</strong> <strong>in</strong>-depth discussion<br />

with each one <strong>of</strong> <strong>the</strong>m <strong>and</strong> caught a<br />

glimpse <strong>of</strong> what was go<strong>in</strong>g on <strong>in</strong> each<br />

project. In fact, it was an unforgettable<br />

experience for me as I was exposed to<br />

so many different projects with<strong>in</strong> such<br />

a short period <strong>of</strong> time.<br />

20TH APRIL: CHURCHILL<br />

HOSPITAL<br />

My last stop was <strong>the</strong> Churchill<br />

Hospital <strong>in</strong> Oxford, a beautiful college<br />

town <strong>and</strong> host to <strong>the</strong> University <strong>of</strong><br />

Oxford. Dr Elizabeth Macaulay, Head<br />

<strong>of</strong> Radiation <strong>Physics</strong>, was my host <strong>in</strong><br />

this visit <strong>and</strong> gave me a quick tour <strong>of</strong><br />

<strong>the</strong> facility (figure 5). My talk on<br />

kVCBCT was well received <strong>and</strong><br />

generated a lot <strong>of</strong> discussions on<br />

CBCT applications <strong>and</strong> imag<strong>in</strong>g<br />

doses. Three research scientists from<br />

diagnostic imag<strong>in</strong>g rema<strong>in</strong>ed after my<br />

talk <strong>and</strong> we had fur<strong>the</strong>r discussions<br />

on <strong>the</strong> status <strong>and</strong> future directions <strong>of</strong><br />

CBCT as compared to <strong>the</strong> CT<br />

technology. I acknowledged that our<br />

current CBCT technology was still not<br />

mature yet, <strong>and</strong> more research work<br />

would be needed from both academia<br />

<strong>and</strong> <strong>in</strong>dustry to fur<strong>the</strong>r improve it to<br />

be more efficient <strong>and</strong> safer for <strong>the</strong><br />

patients. As our colleagues <strong>in</strong> CT are<br />

I had a<br />

pleasant<br />

<strong>and</strong> <strong>in</strong>depth<br />

discussion<br />

with each<br />

one <strong>of</strong><br />

<strong>the</strong>m<br />

“<br />

”<br />

TRAVEL AWARD | SCOPE<br />

do<strong>in</strong>g everyth<strong>in</strong>g <strong>the</strong>y can to optimise<br />

<strong>the</strong> scan protocol <strong>and</strong> reduce <strong>the</strong> dose<br />

to patients, we should also be engaged<br />

<strong>in</strong> efforts to optimise our cl<strong>in</strong>ical<br />

rout<strong>in</strong>es so that low-dose CBCT can be<br />

adm<strong>in</strong>istered to patients <strong>in</strong> an optimal<br />

<strong>and</strong> <strong>in</strong>dividual way.<br />

This concluded my 10-day visit to<br />

five great <strong>in</strong>stitutions <strong>in</strong> <strong>the</strong> UK.<br />

Dur<strong>in</strong>g this trip, I not only met many<br />

wonderful colleagues <strong>in</strong> <strong>the</strong> UK <strong>and</strong><br />

learnt a lot about <strong>the</strong>ir research<br />

projects <strong>and</strong> cl<strong>in</strong>ical practices, but also<br />

shared my experiences with <strong>the</strong>m on<br />

some mutually <strong>in</strong>terest<strong>in</strong>g topics,<br />

which was <strong>in</strong>deed an <strong>in</strong>valuable<br />

experience to me <strong>and</strong> my future career<br />

development. I would like to take this<br />

opportunity to express my s<strong>in</strong>cere<br />

gratitude to Drs Andy Beavis, Alan<br />

Nahum, Vivian Consgrove, Phil Evans<br />

<strong>and</strong> Elizabeth Macaulay for <strong>the</strong>ir<br />

valuable time <strong>and</strong> genu<strong>in</strong>e hospitality.<br />

F<strong>in</strong>ally, I’d like to thank both AAPM<br />

<strong>and</strong> IPEM for this wonderful travel<br />

grant that allowed me to visit <strong>the</strong> UK<br />

<strong>and</strong> exchange ideas <strong>and</strong> share my<br />

research work with my fellow<br />

physicists <strong>in</strong> <strong>the</strong> UK.<br />

SCOPE | SEPTEMBER 2012 | 21


Austrian Medical Center Upgrades Cancer Treatment System to Accelerate<br />

Patient Care with <strong>Elekta</strong>’s Ultra-fast Agility Austrian<br />

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systems or<br />

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systems. For<br />

more<br />

<strong>in</strong>formation,<br />

visit<br />

www.elekta.com/agility<br />

www .elekta.com/agility<br />

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4513 371 1012 08:12


FIGURE 1.<br />

A slide from<br />

David Willis’ talk.<br />

▼<br />

MEETING REPORTS | SCOPE<br />

BESPOKE SOFTWARE IN MEDICAL PHYSICS<br />

AND CLINICAL ENGINEERING CONFERENCE<br />

ANDREW ROBINSON The Harley Street Cl<strong>in</strong>ic, London<br />

UCLH INSTITUTE FOR CHILD HEALTH 28th May 2012<br />

IT WAS A WONDERFULLY SUNNY DAY IN MAY<br />

when nearly 90 delegates descended on London for this<br />

conference organised by IPEM’s Informatics <strong>and</strong><br />

Comput<strong>in</strong>g Special Interest Group (ICSIG). The Special<br />

Interest Group was keen to highlight <strong>the</strong> key work that<br />

is performed by medical physicists <strong>and</strong> cl<strong>in</strong>ical<br />

eng<strong>in</strong>eers <strong>in</strong> design<strong>in</strong>g, develop<strong>in</strong>g <strong>and</strong> ma<strong>in</strong>ta<strong>in</strong><strong>in</strong>g<br />

bespoke s<strong>of</strong>tware that is used <strong>in</strong> <strong>the</strong>ir departments.<br />

Presentations on a variety <strong>of</strong> applications across all<br />

medical physics <strong>and</strong> cl<strong>in</strong>ical eng<strong>in</strong>eer<strong>in</strong>g specialities<br />

were delivered, as well as a large collection <strong>of</strong> scientific<br />

posters that delegates could peruse at <strong>the</strong>ir leisure<br />

dur<strong>in</strong>g <strong>the</strong> breaks.<br />

PRESENTATIONS<br />

David Willis (Norfolk <strong>and</strong> Norwich University<br />

Hospital, Norwich) opened <strong>the</strong> conference with an<br />

<strong>in</strong>formative presentation entitled ‘Bespoke s<strong>of</strong>tware:<br />

concept to cl<strong>in</strong>ical’, where he went through his<br />

experience <strong>of</strong> s<strong>of</strong>tware development from a<br />

commercial, research <strong>and</strong> cl<strong>in</strong>ical perspective (figure 1).<br />

His presentation summed up <strong>the</strong> role <strong>of</strong> <strong>the</strong> bespoke<br />

s<strong>of</strong>tware/<strong>in</strong>-house developer well. He also hit <strong>the</strong> nail<br />

on <strong>the</strong> head with <strong>the</strong> <strong>of</strong>ten found problem <strong>in</strong><br />

departments that rely on one or two people to make<br />

bespoke s<strong>of</strong>tware: ‘Couldn’t write<br />

us a program to do that?’, a statement that may<br />

resonate with some readers! It was also <strong>in</strong>terest<strong>in</strong>g to<br />

hear about some <strong>of</strong> <strong>the</strong> radio<strong>the</strong>rapy-related s<strong>of</strong>tware<br />

that he has developed, <strong>in</strong>clud<strong>in</strong>g s<strong>of</strong>tware to perform<br />

transit EPID dosimetry, an area where <strong>the</strong>re are few<br />

commercial alternatives.<br />

A highly enjoyable talk was given by <strong>the</strong><br />

conference’s <strong>in</strong>vited speaker Ian Wells (University <strong>of</strong><br />

Surrey, Guildford). In his talk ‘In-house s<strong>of</strong>tware<br />

development: a retrospective view’, he gave an<br />

overview <strong>of</strong> how comput<strong>in</strong>g had changed dur<strong>in</strong>g his<br />

career, as well as highlight<strong>in</strong>g <strong>the</strong> importance <strong>of</strong><br />

ensur<strong>in</strong>g that s<strong>of</strong>tware meets appropriate st<strong>and</strong>ards<br />

from both a patient safety <strong>and</strong> pr<strong>of</strong>essional po<strong>in</strong>t <strong>of</strong><br />

view. He had four questions for <strong>in</strong>-house s<strong>of</strong>tware<br />

developers to take away with <strong>the</strong>m: is your s<strong>of</strong>tware<br />

durable? Are your systems safe? Is your methodology<br />

appropriate? Are your qualifications suitable, <strong>and</strong> does<br />

SCOPE | SEPTEMBER 2012 | 23<br />


▼<br />

SCOPE | MEETING REPORTS<br />

24 | SEPTEMBER 2012 | SCOPE<br />

FIGURE 2.<br />

A slide from Ian<br />

Well’s talks.<br />

▼<br />

FIGURE 3.<br />

Overview slide for<br />

Ed McDonagh <strong>and</strong><br />

Laurence K<strong>in</strong>g’s<br />

presentation.<br />


FIGURE 4.<br />

Delegates<br />

enjoy<strong>in</strong>g a c<strong>of</strong>fee<br />

break.<br />

▼<br />

this really matter? Pr<strong>of</strong>essor Wells also talked about <strong>the</strong><br />

use <strong>of</strong> s<strong>of</strong>tware as a medical device <strong>and</strong> <strong>the</strong> importance<br />

<strong>of</strong> know<strong>in</strong>g what any s<strong>of</strong>tware that you develop will be<br />

used for once you have released it, cit<strong>in</strong>g an example<br />

where he was asked to be an expert witness <strong>in</strong> a<br />

crim<strong>in</strong>al trial follow<strong>in</strong>g <strong>the</strong> analysis <strong>of</strong> data us<strong>in</strong>g<br />

s<strong>of</strong>tware that he had developed (figure 2).<br />

By far <strong>the</strong> most animated presentation <strong>of</strong> <strong>the</strong> day<br />

was by Ed McDonagh <strong>and</strong> Laurence K<strong>in</strong>g (Royal<br />

Marsden Hospital, London), whose presentation<br />

dazzled <strong>the</strong> audience with <strong>the</strong>ir work on automat<strong>in</strong>g<br />

dose audits <strong>in</strong> diagnostic radiology through a variety<br />

<strong>of</strong> techniques, <strong>in</strong>clud<strong>in</strong>g optical character recognition<br />

s<strong>of</strong>tware (figure 3). As dose audits can be particularly<br />

time consum<strong>in</strong>g <strong>and</strong> span multiple equipment<br />

manufacturers, <strong>the</strong>ir work to automate this process<br />

across multiple manufacturers has a significant impact<br />

on reduc<strong>in</strong>g <strong>the</strong>ir workload, <strong>and</strong> is someth<strong>in</strong>g that<br />

o<strong>the</strong>r centres may wish to look <strong>in</strong>to.<br />

There were a couple <strong>of</strong> talks from scientists Marc<br />

White (National Hospital for Neurology <strong>and</strong><br />

Neurosurgery, London) <strong>and</strong> Peter Wright (University<br />

Hospital <strong>of</strong> North Staffordshire, Stoke on Trent) about<br />

applications <strong>of</strong> bespoke s<strong>of</strong>tware <strong>in</strong> MRI. One th<strong>in</strong>g<br />

that I learned was how vast <strong>the</strong> DICOM st<strong>and</strong>ard<br />

actually is, <strong>and</strong> that it even has a ‘tag’ for how many<br />

legs a patient has. An <strong>in</strong>terest<strong>in</strong>g po<strong>in</strong>t that was<br />

discussed dur<strong>in</strong>g <strong>the</strong> MRI talks was that QA <strong>of</strong><br />

MEETING REPORTS | SCOPE<br />

diffusion techniques <strong>in</strong> MRI will be <strong>of</strong> vast importance<br />

soon as neurosurgeons heavily rely on <strong>the</strong> <strong>in</strong>formation<br />

yielded by this type <strong>of</strong> scan.<br />

At lunchtime delegates took <strong>the</strong> opportunity to look<br />

at <strong>the</strong> large collection <strong>of</strong> posters that were on show, as<br />

well as speak with <strong>the</strong> authors about <strong>the</strong> work on<br />

display. One author even bought an <strong>in</strong>teractive<br />

demonstration to accompany <strong>the</strong>ir poster on<br />

applications <strong>of</strong> MatSOAP (Rasam Teymouri). The<br />

poster session was a good opportunity to network,<br />

<strong>and</strong> also for delegates to discuss ideas with each o<strong>the</strong>r<br />

about implement<strong>in</strong>g different s<strong>of</strong>tware solutions back<br />

<strong>in</strong> <strong>the</strong>ir respective hospitals.<br />

DISCUSSION<br />

At <strong>the</strong> end <strong>of</strong> <strong>the</strong> meet<strong>in</strong>g <strong>the</strong>re was time for a<br />

discussion about various topics that had come up <strong>in</strong><br />

<strong>the</strong> day. One area that was highlighted was <strong>the</strong> need to<br />

have an appropriate amount <strong>of</strong> comput<strong>in</strong>g covered <strong>in</strong><br />

<strong>the</strong> new Modernis<strong>in</strong>g Scientific Careers curriculum for<br />

medical physics <strong>and</strong> cl<strong>in</strong>ical eng<strong>in</strong>eers. Ano<strong>the</strong>r was<br />

<strong>the</strong> desire for more <strong>of</strong> a ‘community’ for pr<strong>of</strong>essionals<br />

work<strong>in</strong>g <strong>in</strong> medical physics <strong>and</strong> cl<strong>in</strong>ical eng<strong>in</strong>eer<strong>in</strong>g,<br />

where comput<strong>in</strong>g advice could be sought <strong>and</strong><br />

resources shared. All <strong>in</strong> all <strong>the</strong> conference seemed to be<br />

well received, with <strong>the</strong> potential for similar meet<strong>in</strong>gs<br />

<strong>in</strong> <strong>the</strong> future a dist<strong>in</strong>ct possibility given <strong>the</strong> <strong>in</strong>terest<br />

shown <strong>in</strong> this meet<strong>in</strong>g (figure 4). n<br />

SCOPE | SEPTEMBER 2012 | 25


SCOPE | MEETING REPORTS<br />

IPEM TRAVEL BURSARY: 2012 ESTRO 31/<br />

WORLD CONGRESS OF BRACHYTHERAPY<br />

AHAMED BADUSHA MOHAMED YOOSUF Nor<strong>the</strong>rn Irel<strong>and</strong> Cancer Centre, Belfast<br />

BARCELONA 9th–13th May 2012<br />

THE EUROPEAN SOCIETY OF RADIOTHERAPY AND<br />

Oncology (ESTRO) is an <strong>in</strong>terdiscipl<strong>in</strong>ary society with<br />

an aim to advance all aspects <strong>of</strong> radiation oncology.<br />

Events are organised to facilitate <strong>the</strong> meet<strong>in</strong>g <strong>of</strong><br />

pr<strong>of</strong>essionals to share <strong>the</strong>ir ideas <strong>and</strong> work. This year<br />

ESTRO 31 <strong>and</strong> <strong>the</strong> World Congress <strong>of</strong> Brachy<strong>the</strong>rapy<br />

(WCB) were organised as a jo<strong>in</strong>t conference. Be<strong>in</strong>g an<br />

Indian medical physicist work<strong>in</strong>g <strong>in</strong> <strong>the</strong> UK, <strong>the</strong>re is so<br />

much that I wanted to learn <strong>and</strong> experience for myself<br />

about radio<strong>the</strong>rapy practice <strong>in</strong> Europe. As a recipient <strong>of</strong><br />

an IPEM bursary award, I had <strong>the</strong> opportunity to attend<br />

<strong>the</strong> ESTRO 31/WCB conference from 9th–13th May<br />

2012, held <strong>in</strong> <strong>the</strong> International Convention Centre <strong>in</strong><br />

Barcelona. The city <strong>of</strong>fers a feast <strong>of</strong> sculptures, pa<strong>in</strong>t<strong>in</strong>gs,<br />

mosaics, impressive architecture <strong>and</strong> fashion. Especially<br />

remarkable is <strong>the</strong> work <strong>of</strong> architect Antoni Gaudí<br />

(figures 1 <strong>and</strong> 2), which can be seen throughout <strong>the</strong> city.<br />

GLOBAL CONFERENCE<br />

This year’s conference was a huge success with almost<br />

4,000 delegates from 50 different countries <strong>in</strong><br />

attendance. Eighty exhibitors <strong>in</strong> <strong>the</strong> 10,000 m² exhibition<br />

area provided <strong>the</strong> opportunity to discover <strong>the</strong> latest<br />

products <strong>and</strong> services with<strong>in</strong> radiation oncology. There<br />

were 300 <strong>in</strong>vited speakers, 188 oral presentations, 241<br />

oral posters <strong>and</strong> 662 e-posters. At any one time <strong>the</strong>re<br />

were eight parallel streams spread across different<br />

auditoriums <strong>of</strong> <strong>the</strong> International Convention Centre<br />

(figure 3), allow<strong>in</strong>g delegates <strong>the</strong> ability to attend<br />

relevant sessions throughout <strong>the</strong> conference.<br />

I predom<strong>in</strong>antly attended World Congress <strong>of</strong><br />

Brachy<strong>the</strong>rapy sessions. This is a 4-yearly conference<br />

<strong>and</strong> is attended by physicians, physicists, biologists,<br />

technicians <strong>and</strong> company reps from all over <strong>the</strong> world<br />

with a keen <strong>in</strong>terest <strong>in</strong> brachy<strong>the</strong>rapy. This is <strong>the</strong> fifth<br />

edition <strong>of</strong> this jo<strong>in</strong>t meet<strong>in</strong>g <strong>and</strong> <strong>the</strong> programme took<br />

place over 4 days, <strong>in</strong>clud<strong>in</strong>g a pre-meet<strong>in</strong>g course<br />

cover<strong>in</strong>g many aspects <strong>of</strong> brachy<strong>the</strong>rapy.<br />

The scientific programme was organised by Groupe<br />

Européen de Curiethérapie <strong>and</strong> The European Society for<br />

Therapeutic Radiology <strong>and</strong> Oncology (GEC-ESTRO), <strong>in</strong><br />

co-operation with <strong>the</strong> American Brachy<strong>the</strong>rapy Society<br />

(ABS), Asociacion Lat<strong>in</strong>o-americana de Terapia Radiante<br />

Oncologica (ALATRO), Indian Brachy<strong>the</strong>rapy Society<br />

(IBS) <strong>and</strong> Australian Brachy<strong>the</strong>rapy Group (ABG). My<br />

goal on attend<strong>in</strong>g this conference was to exp<strong>and</strong> my<br />

current knowledge <strong>of</strong> brachy<strong>the</strong>rapy physics <strong>and</strong> ga<strong>the</strong>r<br />

useful <strong>in</strong>formation which could be adopted <strong>in</strong> our<br />

centre’s practice to improve our service.<br />

The first day <strong>of</strong> WCB (9th May) started with a premeet<strong>in</strong>g<br />

workshop on ‘Recent advances <strong>in</strong><br />

brachy<strong>the</strong>rapy physics’ that brought toge<strong>the</strong>r em<strong>in</strong>ent<br />

speakers from a variety <strong>of</strong> backgrounds, both medical<br />

<strong>and</strong> scientific, from Europe <strong>and</strong> <strong>the</strong> USA. The workshop<br />

demonstrated <strong>the</strong> most recent advances <strong>in</strong> high dose<br />

26 | SEPTEMBER 2012 | SCOPE<br />

rate (HDR) <strong>and</strong> low dose rate (LDR) brachy<strong>the</strong>rapy.<br />

Topics <strong>in</strong>cluded source calibration, quality assurance,<br />

3D conformal imag<strong>in</strong>g, advanced treatment plann<strong>in</strong>g<br />

us<strong>in</strong>g model-based algorithms, <strong>in</strong> vivo dosimetry,<br />

uncerta<strong>in</strong>ties <strong>in</strong> brachy<strong>the</strong>rapy <strong>and</strong> pr<strong>of</strong>essional society<br />

recommendations.<br />

The use <strong>of</strong> model-based algorithms <strong>in</strong> brachy<strong>the</strong>rapy<br />

treatment plann<strong>in</strong>g was reported by Luc Beaulieu<br />

(Laval University Cancer Research Centre, Québec,<br />

Canada) <strong>and</strong> a review <strong>of</strong> current developments <strong>in</strong><br />

plann<strong>in</strong>g systems was discussed. In current practice, all<br />

dose calculations <strong>in</strong> brachy<strong>the</strong>rapy treatment plann<strong>in</strong>g<br />

are based on AAPM Task Group (TG) Report 43 which<br />

utilises a factor-based algorithm. In a recent study<br />

published by Mark Rivard et al. (United States), <strong>the</strong><br />

limitations <strong>of</strong> TG 43 were described <strong>and</strong> it was found<br />

that <strong>in</strong> lower photon energies, as used <strong>in</strong> brachy<strong>the</strong>rapy,<br />

<strong>the</strong> absorbed dose <strong>in</strong> water to tissue differs due to<br />

higher photoelectric effect cross-sections <strong>of</strong> tissue<br />

compared to water. Similarly, <strong>the</strong> mass attenuation<br />

coefficient <strong>of</strong> tissues differs at low photon energies.<br />

Dose calculation algorithms are be<strong>in</strong>g developed based<br />

on Monte Carlo methods, collapsed cone <strong>and</strong> solv<strong>in</strong>g<br />

<strong>the</strong> l<strong>in</strong>ear Boltzmann transport equation. Also reported<br />

was <strong>the</strong> recommendation that rout<strong>in</strong>e <strong>in</strong> vivo dosimetry<br />

should be <strong>in</strong>troduced <strong>in</strong> brachy<strong>the</strong>rapy procedures, as at<br />

present <strong>the</strong>se are performed without any record <strong>and</strong><br />

verify systems.<br />

INTRODUCTORY SESSIONS<br />

The <strong>of</strong>ficial open<strong>in</strong>g ceremony took place at 6pm <strong>in</strong> <strong>the</strong><br />

ma<strong>in</strong> auditorium with a special lecture by <strong>the</strong> keynote<br />

speaker Manel Esteller (IDIBELL – Bellvitge Biomedical<br />

Research <strong>Institute</strong>, Barcelona, Spa<strong>in</strong>), about medical<br />

applications <strong>of</strong> epigenetics, a study <strong>of</strong> heritable changes<br />

<strong>in</strong> gene expression caused by mechanisms o<strong>the</strong>r than<br />

changes <strong>in</strong> <strong>the</strong> underly<strong>in</strong>g DNA sequence, <strong>in</strong> health <strong>and</strong><br />

disease. After <strong>the</strong> lecture we were enterta<strong>in</strong>ed by <strong>the</strong><br />

<strong>in</strong>novative music show <strong>of</strong> Pagagn<strong>in</strong>i (figure 4), who<br />

brought to life some <strong>of</strong> <strong>the</strong> most treasured musical<br />

pieces <strong>in</strong> <strong>the</strong> key <strong>of</strong> comedy. The day was rounded <strong>of</strong>f<br />

by a special open<strong>in</strong>g reception <strong>in</strong> <strong>the</strong> exhibition area<br />

where <strong>the</strong> technical exhibition was formally opened.<br />

With such a massive exhibition <strong>and</strong> hundreds <strong>of</strong><br />

scientific posters, <strong>the</strong> conference had an extremely<br />

vivacious atmosphere.<br />

Thursday began with <strong>the</strong> symposium on ‘Modern<br />

brachy<strong>the</strong>rapy: role <strong>of</strong> new image modalities’ with six<br />

presentations discuss<strong>in</strong>g <strong>the</strong> latest imag<strong>in</strong>g <strong>in</strong>novations,<br />

from orthogonal radiograph to functional imag<strong>in</strong>g, <strong>and</strong><br />

<strong>the</strong>ir impact <strong>in</strong> brachy<strong>the</strong>rapy. Although every<br />

presentation was <strong>in</strong>formative, <strong>the</strong> topic I found most<br />

appeal<strong>in</strong>g was <strong>the</strong> role <strong>of</strong> ultrasound <strong>in</strong> modern<br />

brachy<strong>the</strong>rapy. In brachy<strong>the</strong>rapy, ultrasound has a role<br />

<strong>in</strong> prostate, gynaecological <strong>and</strong> <strong>in</strong>terstitial applications.


FIGURE 1<br />

[TOP LEFT]<br />

Casa Batlló,<br />

Barcelona.<br />

▼<br />

FIGURE 2<br />

[TOP RIGHT]<br />

La Sagrada<br />

Familia,<br />

Barcelona.<br />

▼<br />

FIGURE 3<br />

Barcelona’s<br />

International<br />

Convention<br />

Centre (CCIB).<br />

▼<br />

MEETING REPORTS | SCOPE<br />

SCOPE | SEPTEMBER 2012 | 27<br />


▼<br />

SCOPE | MEETING REPORTS<br />

28 | SEPTEMBER 2012 | SCOPE<br />

FIGURE 4.<br />

Pagagn<strong>in</strong>i music<br />

show.<br />

▼<br />

FIGURE 5.<br />

[LEFT]<br />

Discussion <strong>in</strong> <strong>the</strong><br />

poster area<br />

dur<strong>in</strong>g a c<strong>of</strong>fee<br />

break.<br />

▼<br />

FIGURE 6.<br />

[RIGHT]<br />

Poster<br />

presentation.<br />


Developments <strong>in</strong> ultrasound were fundamental to <strong>the</strong><br />

rise <strong>in</strong> activity <strong>in</strong> prostate brachy<strong>the</strong>rapy <strong>in</strong> recent years<br />

based on <strong>the</strong> transrectal ultrasound-guided transper<strong>in</strong>eal<br />

implant technique.<br />

Ultrasound techniques have matured with fur<strong>the</strong>r<br />

scientific developments <strong>and</strong> are <strong>in</strong>tegrated with modern<br />

dosimetry algorithms; image fusion techniques enable<br />

ultrasound to be comb<strong>in</strong>ed with computed tomography<br />

(CT) <strong>and</strong> magnetic resonance imag<strong>in</strong>g (MRI) <strong>in</strong> prostate<br />

brachy<strong>the</strong>rapy which can result <strong>in</strong> accurate real-time<br />

imag<strong>in</strong>g <strong>and</strong> may translate <strong>in</strong>to better patient dosimetry.<br />

The use <strong>of</strong> ultrasound images <strong>in</strong> gynaecological<br />

brachy<strong>the</strong>rapy was presented by Sylvia Van Dyk (Peter<br />

MacCallum Cancer Centre, East Melbourne, Victoria,<br />

Australia). With <strong>the</strong> advent <strong>of</strong> high-quality threedimensional<br />

imag<strong>in</strong>g, ultrasound can provide an<br />

excellent representation <strong>of</strong> <strong>the</strong> cervix <strong>and</strong> uterus<br />

enabl<strong>in</strong>g <strong>the</strong> def<strong>in</strong>ition <strong>of</strong> cl<strong>in</strong>ical target volume (CTV) as<br />

per <strong>the</strong> GEC-ESTRO requirements. It was demonstrated<br />

that <strong>the</strong> size <strong>and</strong> shape <strong>of</strong> <strong>the</strong> cervix measured <strong>in</strong><br />

ultrasound <strong>and</strong> MRI images correlate well. For those<br />

centres with limited or no MRI facility, ultrasound<br />

provides a more readily available tool to def<strong>in</strong>e CTV for<br />

conformal plann<strong>in</strong>g.<br />

POSTER PRESENTATION<br />

Throughout <strong>the</strong> duration <strong>of</strong> conference, <strong>the</strong> poster area<br />

<strong>and</strong> manufacturer’s stalls kept us occupied dur<strong>in</strong>g c<strong>of</strong>fee<br />

breaks (figure 5).<br />

MEETING REPORTS | SCOPE<br />

I felt honoured that my abstract was accepted for<br />

poster presentation <strong>and</strong> to be displayed amongst <strong>the</strong> sea<br />

<strong>of</strong> posters (figure 6). On Thursday even<strong>in</strong>g <strong>the</strong>re was a<br />

poster reception at 6.30pm so I te<strong>the</strong>red myself to my<br />

poster dur<strong>in</strong>g this time. The poster is entitled ‘Sector<br />

analysis <strong>of</strong> I-125 prostate implants provides an effective<br />

method compar<strong>in</strong>g pre- <strong>and</strong> post-implant dosimetry’. In<br />

this study, a sector analysis treatment plann<strong>in</strong>g tool was<br />

used as a scientific method <strong>of</strong> exam<strong>in</strong><strong>in</strong>g <strong>the</strong> distribution<br />

<strong>of</strong> dose with<strong>in</strong> 12 separate sub-volumes or ‘sectors’ <strong>of</strong><br />

<strong>the</strong> prostate <strong>and</strong> compared pre- <strong>and</strong> post-implant<br />

dosimetry.<br />

The next two days also consisted <strong>of</strong> an <strong>in</strong>tense<br />

programme <strong>of</strong> educational courses, lunchtime<br />

symposiums, debates <strong>and</strong> scientific sessions. The<br />

conference covered many areas <strong>of</strong> ‘state-<strong>of</strong>-<strong>the</strong>-art’<br />

brachy<strong>the</strong>rapy <strong>and</strong> was very <strong>in</strong>formative. The meet<strong>in</strong>g<br />

was an exceptional educational opportunity <strong>and</strong> a great<br />

forum for discussion. I ga<strong>in</strong>ed an essential <strong>in</strong>sight <strong>in</strong>to<br />

<strong>the</strong> current status <strong>and</strong> future development <strong>of</strong><br />

brachy<strong>the</strong>rapy physics <strong>and</strong> found this ESTRO 31/WCB a<br />

valuable experience.<br />

I am grateful to IPEM for giv<strong>in</strong>g me <strong>the</strong> chance to<br />

attend this very useful conference. I would also like to<br />

thank colleagues <strong>in</strong> Radio<strong>the</strong>rapy <strong>Physics</strong>, Nor<strong>the</strong>rn<br />

Irel<strong>and</strong> Cancer Centre, for <strong>the</strong>ir support <strong>and</strong><br />

encouragement, especially Gerald<strong>in</strong>e Workman <strong>and</strong> Dr<br />

Darren M. Mitchell who supported me <strong>in</strong> <strong>the</strong> research<br />

work reported <strong>in</strong> <strong>the</strong> poster presentation. n<br />

SCOPE | SEPTEMBER 2012 | 29


SCOPE | MEETING REPORTS<br />

REPORT ON NPL CLINICAL TEMPERATURE<br />

MEASUREMENT MEETING<br />

ROSIE RICHARDS North London Consortium<br />

JASON BRITTON Leeds Teach<strong>in</strong>g Hospitals NHS Trust<br />

NATIONAL PHYSICAL LABORATORY 30th January 2012<br />

THE NATIONAL PHYSICS LABORATORY (NPL), AT<br />

<strong>the</strong>ir premises <strong>in</strong> Tedd<strong>in</strong>gton, hosted a one-day<br />

scientific meet<strong>in</strong>g on cl<strong>in</strong>ical temperature measurement<br />

with some excellent speakers <strong>and</strong> <strong>in</strong>terest<strong>in</strong>g<br />

discussions on <strong>the</strong> research <strong>and</strong> development<br />

presented. The meet<strong>in</strong>g was jo<strong>in</strong>tly organised by <strong>the</strong><br />

National Physical Laboratory <strong>and</strong> <strong>the</strong> IPEM<br />

Physiological Measurement Special Interest Group.<br />

The morn<strong>in</strong>g keynote speaker was Helen McEvoy<br />

(NPL, Tedd<strong>in</strong>gton), who talked about cl<strong>in</strong>ical<br />

<strong>the</strong>rmometry us<strong>in</strong>g tympanic <strong>the</strong>rmometers. Helen has<br />

been <strong>in</strong>vestigat<strong>in</strong>g different approaches to <strong>the</strong> tra<strong>in</strong><strong>in</strong>g<br />

<strong>of</strong> cl<strong>in</strong>ical staff <strong>in</strong> <strong>the</strong> appropriate use <strong>of</strong> <strong>the</strong> devices,<br />

such that <strong>the</strong> uncerta<strong>in</strong>ty associated with <strong>the</strong> technique<br />

may be reduced. She covered <strong>the</strong> factors to consider<br />

when measur<strong>in</strong>g temperature <strong>and</strong> <strong>the</strong> risks to consider<br />

when us<strong>in</strong>g such a device. The risks <strong>in</strong>clude: (1)<br />

misdiagnosis due to an <strong>in</strong>accurate read<strong>in</strong>g which could<br />

be due to poor calibration, h<strong>and</strong>l<strong>in</strong>g or storage, or (2)<br />

<strong>in</strong>jury due to <strong>the</strong> probe be<strong>in</strong>g pushed too far <strong>in</strong>to <strong>the</strong><br />

ear or cross-contam<strong>in</strong>ation. A focussed 1-hour tra<strong>in</strong><strong>in</strong>g<br />

programme has now been developed work<strong>in</strong>g with<br />

Oxford Radcliffe Hospitals NHS Trust which can now<br />

be purchased <strong>and</strong> is delivered by NPL.<br />

TIME FOR A CHANGE<br />

The second speaker was Martha Sund-Lev<strong>and</strong>er<br />

(Hoegl<strong>and</strong> Hospital, Eksjo, Sweden), whose<br />

presentation entitled ‘Time for a change when<br />

assess<strong>in</strong>g <strong>and</strong> evaluat<strong>in</strong>g body temperature <strong>in</strong> cl<strong>in</strong>ical<br />

practice’ looked at <strong>the</strong> variability <strong>of</strong> cl<strong>in</strong>ical<br />

temperature measurement <strong>and</strong> <strong>the</strong> factors that may<br />

affect <strong>the</strong> read<strong>in</strong>gs <strong>in</strong> different healthcare sett<strong>in</strong>gs. She<br />

discussed a literature review carried out by her <strong>and</strong><br />

colleagues review<strong>in</strong>g <strong>the</strong> variability <strong>of</strong> temperature<br />

measurements made at different body sites <strong>and</strong> how<br />

this could impact on <strong>the</strong> cl<strong>in</strong>ical management <strong>of</strong><br />

patients. Her work also looked at <strong>the</strong> effects <strong>of</strong> age<strong>in</strong>g<br />

on normal body temperature ranges. It has been<br />

identified that elderly patients with dementia may be<br />

at risk <strong>of</strong> hypo<strong>the</strong>rmia as slightly lower than normal<br />

temperature read<strong>in</strong>gs <strong>in</strong> this patient cohort may not be<br />

seen as cl<strong>in</strong>ically significant. The discussions follow<strong>in</strong>g<br />

prompted Francis R<strong>in</strong>g (University <strong>of</strong> Glamorgan,<br />

Pontypridd) to comment that paracetamol (which<br />

Martha had discussed <strong>in</strong> relation to its effect on<br />

temperature) was not an anti-<strong>in</strong>flammatory drug,<br />

hav<strong>in</strong>g only analgesic effects, <strong>and</strong> was not now<br />

rout<strong>in</strong>ely used <strong>in</strong> cl<strong>in</strong>ical practice.<br />

Follow<strong>in</strong>g this, <strong>the</strong> programme moved onto an<br />

<strong>in</strong>terest<strong>in</strong>g presentation by Sheera Su<strong>the</strong>rl<strong>and</strong><br />

(Churchill Hospital, Oxford) who has researched <strong>the</strong><br />

potential <strong>of</strong> monitor<strong>in</strong>g <strong>the</strong> core temperature <strong>of</strong><br />

patients (with established renal failure) dur<strong>in</strong>g<br />

30 | SEPTEMBER 2012 | SCOPE<br />

haemodialysis with a <strong>the</strong>rmal imag<strong>in</strong>g camera <strong>and</strong><br />

establish<strong>in</strong>g if this can have a positive impact on <strong>the</strong>ir<br />

overall cl<strong>in</strong>ical management. The research<br />

<strong>in</strong>vestigated <strong>the</strong> affects <strong>of</strong> lower<strong>in</strong>g <strong>the</strong> dialysate<br />

temperature to less than 37°C (which is traditionally<br />

used <strong>in</strong> haemodialysis treatments). There is some<br />

evidence that this may be actively warm<strong>in</strong>g <strong>the</strong><br />

patient with a statistically significant difference <strong>in</strong> pre<strong>and</strong><br />

post-dialysis temperatures shown at a level <strong>of</strong> p =<br />

0.001. However, it has been found that some patients<br />

do not tolerate cooler dialysate. Thermal imag<strong>in</strong>g was<br />

also used to <strong>in</strong>vestigate <strong>the</strong> possibility that changes <strong>in</strong><br />

measured core body temperature could be correlated<br />

with a ‘crash’ or hypovolemic event that commonly<br />

occurs. Kev<strong>in</strong> Howell (Royal Free Hospital, London)<br />

commented that hypovolemia may be <strong>the</strong> ma<strong>in</strong> issue<br />

to consider.<br />

DENTAL THERMOGRAPHIC IMAGING<br />

The next speaker, Paula Lancaster (Leeds Dental<br />

<strong>Institute</strong>), showed her work on vital dental<br />

<strong>the</strong>rmographic imag<strong>in</strong>g. The aim <strong>of</strong> <strong>the</strong> work was to<br />

<strong>in</strong>vestigate <strong>the</strong> temperature <strong>of</strong> <strong>the</strong> tooth <strong>in</strong> <strong>the</strong> hope <strong>of</strong><br />

us<strong>in</strong>g this as an objective method to measure <strong>the</strong><br />

vitality <strong>of</strong> <strong>the</strong> tooth.<br />

Currently sensitivity tests are performed to<br />

subjectively assess <strong>the</strong> neural supply to <strong>the</strong> tooth but<br />

this does not tell <strong>the</strong> dentist anyth<strong>in</strong>g about <strong>the</strong> blood<br />

supply. Alternatively an x-ray may be taken <strong>of</strong> <strong>the</strong><br />

patient’s mouth; however, this carries concerns <strong>of</strong> <strong>the</strong><br />

use <strong>of</strong> ionis<strong>in</strong>g radiation (albeit <strong>in</strong> very low doses). A<br />

dental x-ray will only provide anatomical ra<strong>the</strong>r than<br />

physiological <strong>in</strong>formation. The researchers tested <strong>the</strong><br />

<strong>the</strong>ory that <strong>the</strong> central core <strong>of</strong> <strong>the</strong> tooth is warmer<br />

than <strong>the</strong> rest <strong>of</strong> <strong>the</strong> crown by us<strong>in</strong>g a skeletal model.<br />

They found that a <strong>the</strong>rmal gradient could be detected,<br />

when <strong>the</strong> tooth is subjected to external cool<strong>in</strong>g. This<br />

may be promis<strong>in</strong>g for us<strong>in</strong>g a similar model <strong>in</strong> vivo<br />

once ethical approval is obta<strong>in</strong>ed. Paula suggested<br />

that possible applications <strong>of</strong> <strong>the</strong>rmography may<br />

<strong>in</strong>clude:<br />

n assessment <strong>of</strong> vitality <strong>of</strong> <strong>the</strong> tooth <strong>in</strong> people with<br />

toothache <strong>and</strong> <strong>the</strong> provision <strong>of</strong> <strong>in</strong>formation on<br />

which to base treatment decisions,<br />

n assessment <strong>of</strong> <strong>the</strong> extent <strong>of</strong> trauma to <strong>the</strong> teeth,<br />

n assessment <strong>of</strong> <strong>the</strong> development <strong>of</strong> <strong>the</strong> root <strong>in</strong> tooth<br />

transplant (this is currently done us<strong>in</strong>g<br />

radiographs).<br />

Any methods developed need to be simple <strong>and</strong><br />

need to give consistent results. The discussions that<br />

followed this talk brought up issues such as how to<br />

f<strong>in</strong>d <strong>the</strong> emissivity <strong>of</strong> enamel. S<strong>in</strong>ce <strong>the</strong> tests are<br />

look<strong>in</strong>g for relative differences <strong>in</strong> temperature, it was<br />

suggested that this may not be too important.


The day’s presentations <strong>the</strong>n moved on to research<br />

<strong>in</strong>to <strong>the</strong>rmal symmetry on <strong>the</strong> upper <strong>and</strong> lower<br />

extremities on normal healthy volunteers carried out at<br />

Glamorgan University by Ricardo Vardasca<br />

(University <strong>of</strong> M<strong>in</strong>ho, Braga, Portugal). For this work<br />

high-resolution <strong>the</strong>rmal imag<strong>in</strong>g cameras were used to<br />

capture a large number <strong>of</strong> images <strong>of</strong> <strong>the</strong> upper <strong>and</strong><br />

lower extremities. Unlike previous work <strong>in</strong> <strong>the</strong> area,<br />

<strong>the</strong> images were captured <strong>in</strong> a controlled environment<br />

<strong>and</strong> <strong>the</strong> analysis was not based on s<strong>in</strong>gle po<strong>in</strong>ts. The<br />

images were <strong>the</strong>n collated <strong>and</strong> st<strong>and</strong>ardised us<strong>in</strong>g<br />

geometric models. The models were used to scale <strong>the</strong><br />

images to <strong>the</strong> same shape <strong>and</strong> size for each subject. The<br />

f<strong>in</strong>al outcome showed a small difference <strong>of</strong> 0.5°C ±<br />

0.3°C between left <strong>and</strong> right regions. A difference <strong>of</strong><br />

0.1°C was also found between ventral <strong>and</strong> dorsal<br />

regions. Francis R<strong>in</strong>g commented after <strong>the</strong> presentation<br />

that <strong>the</strong>re is a measurement uncerta<strong>in</strong>ty associated<br />

with <strong>the</strong> cameras which must be accounted for when<br />

review<strong>in</strong>g <strong>the</strong> results. It was also unclear how <strong>the</strong><br />

results could be used <strong>in</strong> <strong>the</strong> management <strong>of</strong> patients<br />

<strong>and</strong> where this may be used <strong>in</strong> <strong>the</strong> care pathway.<br />

The next speaker, Ismael Fern<strong>and</strong>ez Cuevas<br />

(Universidad Politecnica de Madrid), presented results<br />

<strong>of</strong> a pilot study look<strong>in</strong>g at <strong>the</strong> effects <strong>of</strong> <strong>the</strong> circadian<br />

cycle on sk<strong>in</strong> surface temperature. The measurements<br />

were conducted <strong>in</strong> a controlled <strong>the</strong>rmal environment<br />

<strong>and</strong> were taken periodically over a 13-hour day with<br />

The H<strong>and</strong>hound voice-operated<br />

‘h<strong>and</strong>s-free’ h<strong>and</strong> monitor<br />

Designed for use <strong>in</strong> radioisotope h<strong>and</strong>l<strong>in</strong>g<br />

situations where h<strong>and</strong>s could be contam<strong>in</strong>ated.<br />

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names, to aid with HSE compliance.<br />

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clean<strong>in</strong>g <strong>and</strong> decontam<strong>in</strong>ation.<br />

Tel: 01273 497600<br />

MEETING REPORTS | SCOPE<br />

<strong>the</strong> subject st<strong>and</strong><strong>in</strong>g <strong>in</strong> <strong>the</strong> same position. Although<br />

<strong>the</strong>re was no obvious pattern result<strong>in</strong>g from <strong>the</strong><br />

measurements at different times, <strong>the</strong> temperature<br />

fluctuations were fairly constant for all areas <strong>of</strong> <strong>the</strong><br />

body that were analysed. After correct<strong>in</strong>g <strong>the</strong><br />

temperature us<strong>in</strong>g <strong>the</strong> calibration area, <strong>the</strong> data<br />

showed similarities with exist<strong>in</strong>g results <strong>in</strong> this field<br />

by Pr<strong>of</strong>essor R<strong>in</strong>g et al. S<strong>in</strong>ce observations showed that<br />

when <strong>the</strong> body was expect<strong>in</strong>g food <strong>in</strong>take <strong>the</strong><br />

temperature <strong>in</strong>creased, a member <strong>of</strong> <strong>the</strong> audience<br />

suggested that <strong>the</strong> glucose level could be monitored if<br />

<strong>the</strong> experiment was repeated. Discussion also took<br />

place about <strong>the</strong> ‘constant core-variable shell’ <strong>the</strong>ory<br />

that is <strong>of</strong>ten applied to <strong>the</strong>rmal regulation <strong>of</strong> <strong>the</strong><br />

human body.<br />

THYROID-ASSOCIATED EYE DISEASE<br />

John Allen (Freeman Hospital, Newcastle upon Tyne)<br />

was <strong>the</strong> next speaker, present<strong>in</strong>g work on ‘Detect<strong>in</strong>g<br />

<strong>in</strong>flammatory disease <strong>in</strong> patients with active (Graves)<br />

thyroid eye disease’. The treatment regimen used for<br />

thyroid-associated orbitopathy depends on <strong>the</strong><br />

outcomes <strong>of</strong> subjective cl<strong>in</strong>ical assessment. John’s pilot<br />

<strong>in</strong>vestigation was aim<strong>in</strong>g to develop a work<strong>in</strong>g<br />

protocol for <strong>the</strong>rmal imag<strong>in</strong>g <strong>of</strong> <strong>the</strong> eye <strong>and</strong> use it to<br />

explore a range <strong>of</strong> characteristics <strong>in</strong> patients with this<br />

pathology. Complications <strong>in</strong>volved bl<strong>in</strong>k<strong>in</strong>g, sweat<strong>in</strong>g<br />

<strong>and</strong> tear<strong>in</strong>g which may be asymmetric. Before <strong>the</strong><br />

Web: www.sou<strong>the</strong>rnscientific.co.uk<br />

SCOPE | SEPTEMBER 2012 | 31<br />


▼<br />

SCOPE | MEETING REPORTS<br />

images were obta<strong>in</strong>ed <strong>the</strong> environment was cooled to<br />

allow <strong>in</strong>flammatory areas (deeper vessels) to become<br />

dom<strong>in</strong>ant. The <strong>in</strong>itial results were quite encourag<strong>in</strong>g<br />

<strong>and</strong> <strong>the</strong> <strong>the</strong>rmal imag<strong>in</strong>g results demonstrated elevated<br />

temperature <strong>in</strong> <strong>the</strong> eyes <strong>in</strong> patients where <strong>the</strong> disease<br />

was active compared to <strong>in</strong>active. John presented some<br />

statistical analysis to show that a probability graph or<br />

contour plot may be <strong>the</strong> way forward to classify <strong>the</strong>se<br />

patients <strong>in</strong> <strong>the</strong> future. However, this was only based on<br />

a cohort <strong>of</strong> 15 patients <strong>and</strong> <strong>the</strong>refore its statistical<br />

validity is equivocal.<br />

ISO STANDARDS<br />

The second keynote speaker <strong>of</strong> <strong>the</strong> day was Francis<br />

R<strong>in</strong>g, whose presentation was entitled ‘ISO st<strong>and</strong>ards<br />

for fever screen<strong>in</strong>g <strong>and</strong> <strong>the</strong>ir implications’. This<br />

presentation raised questions about <strong>the</strong> feasibility <strong>of</strong><br />

fever screen<strong>in</strong>g on a large scale.<br />

The reason for cont<strong>in</strong>ued <strong>in</strong>vestigations <strong>in</strong>to fever<br />

screen<strong>in</strong>g is that <strong>the</strong>re is always a risk <strong>of</strong> a new<br />

<strong>in</strong>fluenza virus emerg<strong>in</strong>g <strong>and</strong> spread<strong>in</strong>g. This would<br />

cause disruption to society <strong>and</strong> fatalities, especially <strong>in</strong><br />

vulnerable groups such as <strong>the</strong> elderly <strong>and</strong> children.<br />

Francis described <strong>the</strong> various stages <strong>of</strong> an <strong>in</strong>fluenza<br />

p<strong>and</strong>emic before mov<strong>in</strong>g on to speak about fever<br />

screen<strong>in</strong>g requirements. F<strong>in</strong>ally, he presented some<br />

results <strong>of</strong> <strong>the</strong> research <strong>in</strong>vestigat<strong>in</strong>g <strong>the</strong> mean <strong>in</strong>ner<br />

canthus temperature <strong>in</strong> febrile <strong>and</strong> afebrile children<br />

present<strong>in</strong>g at an A&E department <strong>in</strong> Warsaw. It was<br />

unclear from <strong>the</strong> presentation as to why <strong>the</strong> research<br />

could not have been undertaken <strong>in</strong> <strong>the</strong> UK <strong>and</strong> if all <strong>the</strong><br />

possible variables had been sufficiently well controlled<br />

or properly <strong>in</strong>vestigated.<br />

The penultimate speaker, Kev<strong>in</strong> Howell, reviewed<br />

his work on <strong>the</strong> use <strong>of</strong> a low-cost (£2,500), low <strong>the</strong>rmal<br />

<strong>and</strong> spatial resolution (160 × 120 pixels) <strong>the</strong>rmal imager<br />

<strong>in</strong> <strong>the</strong> cl<strong>in</strong>ical assessment <strong>of</strong> patients with Raynaud’s<br />

phenomenon. The aim <strong>of</strong> <strong>the</strong> work was to determ<strong>in</strong>e<br />

whe<strong>the</strong>r <strong>the</strong> low-cost portable <strong>the</strong>rmal camera would<br />

give comparable results to a more expensive device<br />

(£10,000–£11,000) with higher resolution <strong>and</strong> better<br />

<strong>the</strong>rmal resolution which has been used to assess this<br />

cohort <strong>of</strong> patients at <strong>the</strong> Royal Free Hospital. Despite<br />

small differences <strong>in</strong> <strong>the</strong> measured f<strong>in</strong>ger temperatures,<br />

<strong>the</strong> results demonstrated that <strong>the</strong> cheaper <strong>the</strong>rmal<br />

imager can be used <strong>in</strong> assess<strong>in</strong>g patients with<br />

Raynaud’s phenomenon <strong>and</strong> when compared to <strong>the</strong><br />

more expensive device cl<strong>in</strong>ically it would have no<br />

32 | SEPTEMBER 2012 | SCOPE<br />

impact on cl<strong>in</strong>ical management. It was <strong>the</strong>refore<br />

concluded that low spatial resolution is not a limitation<br />

for Raynaud’s phenomenon work (see figure 1).<br />

THERMAL IMAGING APPLICATIONS IN<br />

CRYOTHERAPY<br />

The f<strong>in</strong>al speaker <strong>of</strong> <strong>the</strong> day, Arm<strong>and</strong> Cholewka<br />

(University <strong>of</strong> Silesia, Katowice, Pol<strong>and</strong>), presented on<br />

<strong>the</strong>rmal imag<strong>in</strong>g applications <strong>in</strong> whole-body<br />

cryo<strong>the</strong>rapy. This was an <strong>in</strong>terest<strong>in</strong>g application <strong>of</strong><br />

<strong>the</strong>rmography us<strong>in</strong>g <strong>the</strong> cold environment to constrict<br />

surface vessels <strong>and</strong> detect <strong>and</strong> treat deeper areas <strong>of</strong><br />

<strong>in</strong>flammation. A typical cryosauna has a temperature <strong>of</strong><br />

−120°C <strong>and</strong> <strong>the</strong> patient is required to spend 2–3<br />

m<strong>in</strong>utes at a time <strong>in</strong> it. The aims <strong>of</strong> Arm<strong>and</strong>’s work<br />

were to evaluate <strong>the</strong> effects <strong>of</strong> cryo<strong>the</strong>rapy <strong>and</strong> to<br />

determ<strong>in</strong>e <strong>the</strong> sk<strong>in</strong> response due to <strong>the</strong> low<br />

temperature used <strong>in</strong> whole-body cryo<strong>the</strong>rapy. After <strong>the</strong><br />

patients had been <strong>in</strong> <strong>the</strong> chamber <strong>the</strong>rmal images were<br />

captured <strong>of</strong> different sk<strong>in</strong> segments. These showed a<br />

mean whole-body decrease <strong>in</strong> temperature <strong>of</strong> 5.8°C<br />

with a maximum <strong>of</strong> 8.7°C. After use patients reported a<br />

significant recovery after one to ten cryogenic sessions.<br />

There was also a slight improvement <strong>in</strong> <strong>the</strong> fitness <strong>of</strong><br />

<strong>the</strong> patients. In conclusion, Arm<strong>and</strong> claimed that <strong>the</strong>re<br />

was <strong>in</strong>creased diagnostic value <strong>of</strong> <strong>the</strong>rmal imag<strong>in</strong>g<br />

after body cool<strong>in</strong>g <strong>and</strong> that <strong>the</strong>rmal imag<strong>in</strong>g can be<br />

helpful <strong>in</strong> <strong>the</strong> monitor<strong>in</strong>g <strong>of</strong> <strong>the</strong>rapeutic effects <strong>of</strong><br />

whole-body cryo<strong>the</strong>rapy. However, very little evidence<br />

was presented to support this view <strong>and</strong> it was unclear<br />

from <strong>the</strong> presentation how <strong>the</strong>rmal imag<strong>in</strong>g<br />

contributed to patient care or overall management, <strong>and</strong><br />

where this would be used <strong>in</strong> <strong>the</strong> care <strong>and</strong> diagnostic<br />

pathway.<br />

It was clear from <strong>the</strong> presentations that outside <strong>the</strong><br />

use <strong>of</strong> <strong>the</strong>rmal imag<strong>in</strong>g for patients with Raynaud’s<br />

phenomenon a lot <strong>of</strong> possible cl<strong>in</strong>ical uses are <strong>in</strong> <strong>the</strong><br />

very early stages <strong>of</strong> development <strong>and</strong> have not really<br />

become established <strong>in</strong> ma<strong>in</strong>stream cl<strong>in</strong>ical practice.<br />

SUMMARY<br />

The meet<strong>in</strong>g was attended by about 25 delegates <strong>and</strong><br />

will hopefully become a regular event <strong>in</strong> <strong>the</strong> NPL<br />

calendar s<strong>in</strong>ce it proved to be a great success. n<br />

MORE INFORMATION<br />

All <strong>of</strong> <strong>the</strong> slides <strong>and</strong> talks can be accessed via YouTube at:<br />

http://www.youtube.com/playlist?list=PL08A8E92B0363DA68&fe<br />

ature=plcp<br />

FIGURE 1<br />

Images from <strong>the</strong><br />

more expensive<br />

<strong>the</strong>rmal imag<strong>in</strong>g<br />

camera (left)<br />

when compared<br />

to <strong>the</strong> less<br />

expensive device<br />

(right). As can be<br />

seen, very little<br />

cl<strong>in</strong>ical<br />

difference can be<br />

observed.<br />


MEETINGS 2012/2013<br />

EUROPEAN MEETINGS<br />

Meet<strong>in</strong>g Venue <strong>and</strong> dates More <strong>in</strong>formation<br />

World Molecular Imag<strong>in</strong>g Congress<br />

6th European Conference on Medical<br />

<strong>Physics</strong><br />

IPEM Medical <strong>Physics</strong> <strong>and</strong> <strong>Eng<strong>in</strong>eer<strong>in</strong>g</strong><br />

Conference<br />

Ma<strong>the</strong>matics <strong>of</strong> Medical Devices <strong>and</strong><br />

Surgical Procedures<br />

7th IET International Conference on<br />

Appropriate Healthcare Technologies for<br />

Develop<strong>in</strong>g Countries (AHT2012 )<br />

Annual Meet<strong>in</strong>g <strong>of</strong> <strong>the</strong> German Society <strong>of</strong><br />

Medical <strong>Physics</strong> (DGMP)<br />

International Conference on Medical Image<br />

Comput<strong>in</strong>g <strong>and</strong> Computer Assisted<br />

Intervention<br />

3rd Newport 1-Day Update Course on<br />

Photo<strong>the</strong>rapy Dosimetry<br />

International Cancer Imag<strong>in</strong>g Society 12th<br />

Annual Teach<strong>in</strong>g Course<br />

International Symposium on Biomedical<br />

<strong>Eng<strong>in</strong>eer<strong>in</strong>g</strong> <strong>and</strong> Medical <strong>Physics</strong><br />

European Medical <strong>Physics</strong> <strong>and</strong> <strong>Eng<strong>in</strong>eer<strong>in</strong>g</strong><br />

Conference (EMPEC 2012)<br />

MR Safety Tra<strong>in</strong><strong>in</strong>g Course<br />

4th International Symposium on<br />

Radionuclide Targeted Radio<strong>the</strong>rapy <strong>and</strong><br />

Dosimetry (ISTARD)<br />

12th IEEE International Conference on<br />

BioInformatics <strong>and</strong> Bio<strong>Eng<strong>in</strong>eer<strong>in</strong>g</strong><br />

(BIBE 2012)<br />

2012 International Conference on<br />

NeuroRehabilitation<br />

IAEA International Conference on Radiation<br />

Protection <strong>in</strong> Medic<strong>in</strong>e – Sett<strong>in</strong>g <strong>the</strong> Scene<br />

for <strong>the</strong> Next Decade<br />

38th World Hospital Congress – Future<br />

Healthcare<br />

Dubl<strong>in</strong>, Irel<strong>and</strong><br />

5th–8th September<br />

Sibiu, Romania<br />

6th–9th September<br />

Oxford, UK<br />

10th–12th September<br />

London, UK<br />

17th–19th September<br />

London, UK<br />

18th–19th September<br />

Jena, Germany<br />

26th–29th September<br />

Nice, France<br />

1st–5th October<br />

Newport, Wales, UK<br />

2nd October<br />

Oxford, UK<br />

4th–6th October<br />

Riga, Latvia<br />

10th–12th October<br />

S<strong>of</strong>ia, Bulgaria<br />

18th–20th October<br />

Vienna, Austria<br />

18th–20th October<br />

Milan, Italy<br />

27th–31st October<br />

Larnaca, Cyprus<br />

11th–13th November<br />

Toledo, Spa<strong>in</strong><br />

14th–16th November<br />

Bonn, Germany<br />

3rd–7th December<br />

Oslo, Norway<br />

18th–20th June 2013<br />

INTERNATIONAL NEWS | SCOPE<br />

This is a non-exhaustive list <strong>of</strong> meet<strong>in</strong>gs <strong>of</strong> <strong>in</strong>terest. For IPEM workshops <strong>and</strong> meet<strong>in</strong>gs <strong>and</strong> a full list <strong>of</strong> meet<strong>in</strong>gs, please check <strong>the</strong> IPEM website:<br />

http://www.ipem.ac.uk/Conferences<strong>and</strong>events<br />

http://www.wmicmeet<strong>in</strong>g.org/<br />

http://www.ecmp2012.ro/<br />

http://www.ipem.ac.uk/Conferences<strong>and</strong>events/<br />

mpec/Pages/default.aspx<br />

http://www.ima.org.uk/conferences/conferences_cal<br />

endar/maths_<strong>of</strong>_medical_devices_&_surgical_proce<br />

dures.cfm<br />

http://www.<strong>the</strong>iet.org/aht2012<br />

http://www.conventus.de/dgmp2012/<br />

http://medical.rob.uni-luebeck.de/miccai2012rt/<br />

http://www.b<strong>in</strong>i.rtu.lv/isbemp<br />

http://www.bsbpe.org<br />

Contact ESMRMB Society<br />

http://bibe2012.cs.ucy.ac.cy/<br />

http://www.icnr2012.org<br />

http://www-pub.iaea.org/<br />

mtcd/meet<strong>in</strong>gs/Meet<strong>in</strong>gs2012.asp<br />

http://www.oslo2013.no<br />

SCOPE | SEPTEMBER 2012 | 33<br />


SCOPE | INTERNATIONAL NEWS<br />

MEETINGS 2012/2013<br />

NORTH AMERICAN MEETINGS<br />

Meet<strong>in</strong>g Venue <strong>and</strong> dates More <strong>in</strong>formation<br />

Applied Health <strong>Physics</strong> (5-week course) Oak<br />

Ridge Associated Universities H<strong>and</strong>s-on<br />

Tra<strong>in</strong><strong>in</strong>g <strong>in</strong> <strong>the</strong> Radiological Sciences<br />

Computed Tomography H<strong>and</strong>s-on Workshop<br />

for Physicists<br />

Pr<strong>in</strong>ciples <strong>and</strong> Practices <strong>of</strong> Radiation Safety:<br />

Occupational <strong>and</strong> Environmental Radiation<br />

Protection<br />

ASTRO Annual Meet<strong>in</strong>g<br />

IEEE Nuclear Science Symposium, Medical<br />

Imag<strong>in</strong>g Conference <strong>and</strong> Workshop on<br />

Room-temperature Semiconductor X-ray<br />

<strong>and</strong> Gamma-ray Detectors<br />

Respiratory Motion Management for<br />

Radiation Therapy<br />

Radiological Society <strong>of</strong> North America<br />

(RSNA) Annual Meet<strong>in</strong>g 2012<br />

Practical Aspects <strong>of</strong> Stereotactic Body<br />

Radiation Therapy (SBRT)<br />

HPS Mid-year Topical Meet<strong>in</strong>g on Medical<br />

Health <strong>Physics</strong> <strong>and</strong> Accelerator Dosimetry<br />

7th International Conference on Ethical<br />

Issues <strong>in</strong> Biomedical <strong>Eng<strong>in</strong>eer<strong>in</strong>g</strong><br />

REST OF THE WORLD MEETINGS<br />

Thai International Workshop on New<br />

Technologies <strong>in</strong> Radio<strong>the</strong>rapy<br />

12th International Conference on Radiation<br />

Shield<strong>in</strong>g (ICRS-12) <strong>and</strong> 17th Topical Meet<strong>in</strong>g<br />

<strong>of</strong> <strong>the</strong> Radiation Protection <strong>and</strong> Shield<strong>in</strong>g<br />

Division <strong>of</strong> <strong>the</strong> American Nuclear Society<br />

IC3DDose: 7th International Conference on<br />

3D Radiation Dosimetry (formerly known as<br />

DOSGEL)<br />

<strong>Eng<strong>in</strong>eer<strong>in</strong>g</strong> & Physical Sciences <strong>in</strong> Medic<strong>in</strong>e<br />

Conference (EPSM2012)<br />

IEEE-EMBS – International Conference on<br />

Biomedical <strong>Eng<strong>in</strong>eer<strong>in</strong>g</strong> <strong>and</strong> Sciences<br />

(IECBES 2012)<br />

17th International Conference on <strong>the</strong> Use <strong>of</strong><br />

Computers <strong>in</strong> Radiation Therapy (ICCR)<br />

34 | SEPTEMBER 2012 | SCOPE<br />

Oak Ridge, TN<br />

10th September–12th October<br />

Houston, TX<br />

14th–16th September<br />

Boston, MA<br />

23rd–27th September<br />

Boston, MA<br />

28th–31st October<br />

Anaheim, CA<br />

29th October–3rd November<br />

St Louis, MO<br />

16th–17th November<br />

Chicago, IL<br />

25th–30th November<br />

Stanford, CA<br />

30th November–1st December<br />

Scottsdale, AZ<br />

27th–30th January 2013<br />

New York, NY<br />

20th–21st April 2013<br />

Bangkok, Thail<strong>and</strong><br />

22nd–25th August<br />

Nara, Japan<br />

2nd–7th September<br />

Sydney, Australia<br />

4th–8th November<br />

Gold Coast, Queensl<strong>and</strong>, Australia<br />

2nd–6th December<br />

Langkawi, Malaysia<br />

17th–19th December<br />

Melbourne, Australia<br />

6th–9th May 2013<br />

http://www.orau.org/environmental-assessmentshealth-physics/capabilities/health-physicstra<strong>in</strong><strong>in</strong>g/course-descriptions-<strong>and</strong>-schedules.aspx<br />

http://www.md<strong>and</strong>erson.org/education-<strong>and</strong>research/departments-programs-<strong>and</strong>labs/departments-<strong>and</strong>-divisions/imag<strong>in</strong>gphysics/education/<strong>in</strong>dex.html<br />

https://ecpe.sph.harvard.edu/programs.cfm?CSID=<br />

OERP0913&pg=cluster&CLID=1<br />

https://www.astro.org/Meet<strong>in</strong>gs-<strong>and</strong>-Events/2012-<br />

Annual-Meet<strong>in</strong>g/Index.aspx<br />

http://www.nss-mic.org/2012/NSSMa<strong>in</strong>.asp<br />

http://radonc.wustl.edu/pdf/MMRTCourse.pdf<br />

http://www.rsna.org/Annual_Meet<strong>in</strong>g.aspx<br />

http://hps.org/meet<strong>in</strong>gs/meet<strong>in</strong>g33.html<br />

http://www.downstate.edu/orthopaedics/<br />

bioethicsconf2013/<br />

http://www.cccthai.org/en_/<br />

http://www.icrs12.org/<br />

http://www.ic3ddose.org<br />

http://www.epsmconference.org/<br />

http://iecbes2012.myembs.org/<br />

http://www.iccr2013.org<br />

Email: iccr2013@ar<strong>in</strong>ex.com.au


MEMBERS’ NEWS | SCOPE<br />

Röntgen Prize <strong>of</strong> <strong>the</strong> British Journal <strong>of</strong> Radiology<br />

One <strong>of</strong> our own, Peter Mountford,<br />

was recently awarded <strong>the</strong><br />

prestigious Röntgen Prize <strong>of</strong> <strong>the</strong><br />

British Journal <strong>of</strong> Radiology.<br />

Peter was formerly Director <strong>of</strong><br />

Medical <strong>Physics</strong> <strong>and</strong> Cl<strong>in</strong>ical<br />

Technology, University<br />

Hospital <strong>of</strong> North<br />

Staffordshire, Stoke-on-<br />

Trent, <strong>and</strong> also a Reader <strong>in</strong><br />

<strong>the</strong> School <strong>of</strong> Postgraduate<br />

Medic<strong>in</strong>e <strong>of</strong> Keele<br />

University.<br />

At a reception<br />

held at UKRC <strong>in</strong><br />

Manchester on<br />

Monday 25th<br />

June 2012,<br />

Peter was<br />

awarded <strong>the</strong><br />

2010 Röntgen<br />

Prize <strong>of</strong> <strong>the</strong><br />

British Journal<br />

<strong>of</strong> Radiology. Founded <strong>in</strong> 1924, <strong>in</strong><br />

memory <strong>of</strong> Pr<strong>of</strong>essor W.C.<br />

Röntgen, this prize is awarded<br />

annually to a member, or a team<br />

<strong>of</strong> workers <strong>in</strong>clud<strong>in</strong>g a member,<br />

whose contribution to <strong>the</strong> British<br />

Journal <strong>of</strong> Radiology has<br />

been <strong>of</strong> special merit.<br />

The subject <strong>of</strong> <strong>the</strong><br />

contribution must be<br />

related to radio<strong>the</strong>rapy,<br />

radiobiology or physics.<br />

The BIR stated <strong>in</strong><br />

<strong>the</strong>ir citation that:<br />

‘Throughout his NHS career Dr<br />

Mountford served <strong>the</strong> British<br />

<strong>Institute</strong> <strong>of</strong> Radiology with<br />

dist<strong>in</strong>ction. In 1994 he jo<strong>in</strong>ed <strong>the</strong><br />

Editorial Board <strong>of</strong><br />

<strong>the</strong> British<br />

Journal <strong>of</strong><br />

Radiology<br />

<strong>and</strong> later<br />

became<br />

Deputy<br />

Laser Position<strong>in</strong>g<br />

Innovative equipment for radio<strong>the</strong>rapy<br />

First laser position<strong>in</strong>g system designed<br />

with a double diode.<br />

Switch between red <strong>and</strong> green for each<br />

laser l<strong>in</strong>e at <strong>the</strong> touch <strong>of</strong> a button.<br />

No manual adjustment needed.<br />

Smart Phantom® calibrates to 0.1mm<br />

accuracy.<br />

Editor for physics <strong>and</strong><br />

technology. He additionally<br />

made scientific contributions to<br />

<strong>the</strong> BJR <strong>in</strong> numerous articles<br />

published between 1976 <strong>and</strong><br />

2009 <strong>and</strong>, for 6 years, was a<br />

member <strong>of</strong> <strong>the</strong> BIR Radiation<br />

Protection Committee.<br />

The BIR recognises with<br />

gratitude Peter Mountford's long<br />

<strong>and</strong> dist<strong>in</strong>guished association<br />

with its activities <strong>and</strong> is<br />

delighted to award him <strong>the</strong> 2010<br />

Röntgen Prize.’<br />

I th<strong>in</strong>k that our whole<br />

readership would wish to jo<strong>in</strong><br />

me <strong>in</strong> congratulat<strong>in</strong>g Peter on<br />

his achievement.<br />

Peter Mountford (right) <strong>and</strong><br />

Dr Stephen Davies, <strong>the</strong> President<br />

<strong>of</strong> <strong>the</strong> British <strong>Institute</strong> <strong>of</strong><br />

Radiology. Thank you to <strong>the</strong> BIR<br />

for provid<strong>in</strong>g <strong>the</strong> image.<br />

▼<br />

www.osl.uk.com<br />

enquiry@osl.uk.com<br />

+44 (0)1743 462694<br />

SCOPE | SEPTEMBER 2012 | 35<br />


SCOPE | MEMBERS’ NEWS<br />

Robert Neilson<br />

Peter Sharp acknowledges <strong>the</strong> exceptional hard work <strong>of</strong> IPEM’s retir<strong>in</strong>g General Secretary<br />

One can argue as to<br />

who is <strong>the</strong> more<br />

important person <strong>in</strong><br />

<strong>the</strong> <strong>Institute</strong>, <strong>the</strong><br />

President or <strong>the</strong><br />

General Secretary. A President<br />

is ra<strong>the</strong>r like a pigeon, he (or<br />

she) flies <strong>in</strong>, makes a mess <strong>and</strong><br />

<strong>the</strong>n flies <strong>of</strong>f aga<strong>in</strong> after 2 years.<br />

The General Secretary has <strong>the</strong><br />

brush <strong>and</strong> pan <strong>and</strong> is<br />

responsible for clean<strong>in</strong>g up<br />

afterwards.<br />

MAJOR ACHIEVEMENTS<br />

As one <strong>of</strong> <strong>the</strong> first pigeons that<br />

Robert had to clean up after, I<br />

have no doubts about <strong>the</strong><br />

importance <strong>of</strong> <strong>the</strong> role <strong>of</strong> <strong>the</strong><br />

General Secretary. Of course he<br />

is now well supported by an<br />

adm<strong>in</strong>istrative team <strong>in</strong><br />

Fairmount House, but he<br />

carries <strong>the</strong> ultimate<br />

responsibility. I asked Robert<br />

what his greatest challenge had<br />

been <strong>and</strong> certa<strong>in</strong>ly well up <strong>the</strong><br />

top ten list was <strong>the</strong> <strong>in</strong>troduction<br />

<strong>of</strong> <strong>the</strong> new computer system.<br />

Those <strong>of</strong> you who are keen<br />

36 | SEPTEMBER 2012 | SCOPE<br />

subscribers to Private Eye will<br />

frequently read about <strong>the</strong><br />

disasters that befall many<br />

government departments when<br />

<strong>the</strong>y try to <strong>in</strong>troduce new<br />

computer systems <strong>and</strong> IPEM,<br />

while not (yet) featur<strong>in</strong>g <strong>in</strong> that<br />

august organ, was not immune<br />

from that. I have <strong>of</strong>ten said that a<br />

new President has two options;<br />

ei<strong>the</strong>r <strong>in</strong>troduce a new computer<br />

system for <strong>the</strong> <strong>of</strong>fice or<br />

undertake a reorganisation <strong>of</strong><br />

how IPEM works. Ei<strong>the</strong>r way<br />

he/she will have an excuse for<br />

putt<strong>in</strong>g <strong>of</strong>f any difficult decisions<br />

until after <strong>the</strong>ir term <strong>of</strong> <strong>of</strong>fice. But<br />

Robert is <strong>the</strong> man with <strong>the</strong> brush<br />

<strong>and</strong> pan.<br />

“<br />

The General<br />

Secretary has <strong>the</strong><br />

brush <strong>and</strong> pan <strong>and</strong><br />

is responsible for<br />

clean<strong>in</strong>g up<br />

”<br />

Like many lead<strong>in</strong>g lights <strong>in</strong><br />

IPEM Robert has Scottish roots.<br />

Be<strong>in</strong>g a keen amateur<br />

genealogist Robert has traced<br />

one part <strong>of</strong> his family back to St<br />

N<strong>in</strong>ians, near Stirl<strong>in</strong>g. However,<br />

<strong>in</strong> <strong>the</strong> middle <strong>of</strong> <strong>the</strong> n<strong>in</strong>eteenth<br />

century <strong>the</strong>y moved down to<br />

Yorkshire, first to <strong>the</strong> York area<br />

<strong>and</strong> <strong>the</strong>n, his sub-branch, to<br />

Knott<strong>in</strong>gley, where Robert<br />

himself was born. Robert is now<br />

a fully fledged Yorkshireman,<br />

hav<strong>in</strong>g lived <strong>in</strong> <strong>the</strong> county all<br />

his life. Not only does he<br />

love its moors <strong>and</strong><br />

dales but as a<br />

committed Christian<br />

Robert has many<br />

connections through<br />

his work with <strong>the</strong><br />

Congregational<br />

Church <strong>in</strong> Pontefract.<br />

Those <strong>of</strong> us who<br />

have had <strong>the</strong> privilege <strong>of</strong> work<strong>in</strong>g<br />

with Robert over <strong>the</strong> years<br />

appreciate his openness, honesty<br />

<strong>and</strong> full commitment to <strong>the</strong> aims<br />

<strong>of</strong> <strong>the</strong> <strong>Institute</strong>. When I suggested<br />

to Robert that perhaps not be<strong>in</strong>g<br />

a scientist would have been a<br />

disadvantage <strong>in</strong> his early days, he<br />

po<strong>in</strong>ted out that he had always<br />

been keen on science <strong>and</strong> it was<br />

only a quirk <strong>of</strong> <strong>the</strong> educational<br />

system that meant he had ended<br />

up on <strong>the</strong> arts side. Also, <strong>in</strong> his<br />

previous jobs <strong>in</strong> <strong>the</strong> power<br />

<strong>in</strong>dustry, he had worked with<br />

scientists <strong>and</strong> eng<strong>in</strong>eers <strong>and</strong><br />

needed a strong technical<br />

background to carry out audits<br />

<strong>and</strong> manage <strong>the</strong> functions for<br />

which he was responsible at a<br />

power station <strong>and</strong> <strong>in</strong> <strong>the</strong> fuel<br />

supply cha<strong>in</strong>.<br />

That devotion to <strong>the</strong><br />

pr<strong>of</strong>ession showed itself aga<strong>in</strong><br />

when I asked Robert <strong>of</strong> what<br />

achievement he was most proud.<br />

He said that it was <strong>the</strong> work he<br />

did with <strong>the</strong> Science Council, on<br />

behalf <strong>of</strong> <strong>the</strong> <strong>Institute</strong>. Dur<strong>in</strong>g<br />

that time <strong>the</strong> Chartered Scientist<br />

designation was developed <strong>and</strong><br />

he played an important role on<br />

<strong>the</strong> Registration Authority, act<strong>in</strong>g<br />

as its chair dur<strong>in</strong>g <strong>the</strong> crucial<br />

formative period when CSci<br />

st<strong>and</strong>ards were set <strong>and</strong> <strong>in</strong>itial<br />

licences were awarded. In <strong>the</strong><br />

last year he has been <strong>in</strong>volved <strong>in</strong><br />

<strong>in</strong>troduc<strong>in</strong>g <strong>the</strong> RSci <strong>and</strong><br />

RSciTech qualification for<br />

science technologists at different<br />

career stages, with IPEM be<strong>in</strong>g<br />

one <strong>of</strong> <strong>the</strong> first organisations to<br />

be able to award <strong>the</strong> new<br />

designations. There is someth<strong>in</strong>g<br />

<strong>in</strong> <strong>the</strong> genes <strong>of</strong> medical physicists<br />

that makes <strong>the</strong>m cynical about<br />

<strong>the</strong> value <strong>of</strong> qualifications but, <strong>in</strong><br />

a competitive world, marks <strong>of</strong><br />

pr<strong>of</strong>essional st<strong>and</strong><strong>in</strong>g are<br />

<strong>in</strong>creas<strong>in</strong>gly important <strong>and</strong><br />

Robert must be congratulated on<br />

his work.<br />

So how has <strong>the</strong> role <strong>of</strong> <strong>the</strong><br />

General Secretary developed over<br />

<strong>the</strong> time Robert has been <strong>in</strong><br />

<strong>of</strong>fice? He rem<strong>in</strong>ded me <strong>of</strong> a<br />

question that I had asked him at<br />

his <strong>in</strong>terview, ‘Do you feel that<br />

this job is really a full-time one?’<br />

His answer had been that no, it<br />

wasn’t, at least not as we had<br />

described it <strong>in</strong> <strong>the</strong> job<br />

specification, but it should be full<br />

time as <strong>the</strong>re was much more<br />

that needed to be done <strong>and</strong> he<br />

promptly listed all <strong>the</strong> extra<br />

tasks. Despite that he was<br />

appo<strong>in</strong>ted.<br />

CHALLENGES FACED<br />

The ma<strong>in</strong> change has been <strong>the</strong><br />

move from <strong>the</strong> post be<strong>in</strong>g<br />

primarily adm<strong>in</strong>istrative to one <strong>of</strong><br />

be<strong>in</strong>g <strong>the</strong> Chief Executive, <strong>the</strong><br />

person who makes a significant<br />

contribution to <strong>the</strong> strategic<br />

vision <strong>of</strong> <strong>the</strong> <strong>Institute</strong>. Now that<br />

<strong>the</strong> <strong>Institute</strong> has a well-organised<br />

<strong>of</strong>fice to take on <strong>the</strong> many tasks<br />

that an organisation <strong>of</strong> our size<br />

needs do<strong>in</strong>g, <strong>the</strong> role has been<br />

much more h<strong>and</strong>s-<strong>of</strong>f with<br />

Robert <strong>in</strong>creas<strong>in</strong>gly be<strong>in</strong>g asked<br />

to represent <strong>the</strong> <strong>Institute</strong> on<br />

external bodies, such as <strong>the</strong><br />

Science Council. I know that<br />

dur<strong>in</strong>g my time as President I<br />

found it very helpful to have<br />

Robert sitt<strong>in</strong>g next to me at<br />

committee meet<strong>in</strong>gs to provide<br />

wise advice <strong>and</strong> rem<strong>in</strong>d me when<br />

I was stray<strong>in</strong>g from <strong>the</strong> party l<strong>in</strong>e.<br />

Of course <strong>in</strong> <strong>the</strong> past few years<br />

<strong>the</strong> l<strong>and</strong>scape <strong>in</strong> which <strong>the</strong><br />

<strong>Institute</strong> operates has changed<br />

significantly. The <strong>Institute</strong> is faced<br />

with an adm<strong>in</strong>istration <strong>in</strong><br />

Westm<strong>in</strong>ster which does not<br />

always appreciate <strong>the</strong> value <strong>of</strong><br />

pr<strong>of</strong>essional societies <strong>and</strong> seems<br />

to prefer to take on much <strong>of</strong> <strong>the</strong>ir<br />

roles <strong>the</strong>mselves. Robert’s view<br />

<strong>of</strong> <strong>the</strong> challenges fac<strong>in</strong>g his<br />

successor is that <strong>the</strong>y need to<br />

create an organisation that gives


a strong pr<strong>of</strong>essional<br />

leadership. The old model <strong>of</strong> <strong>the</strong><br />

majority <strong>of</strong> work be<strong>in</strong>g carried<br />

out by volunteers is now not so<br />

appropriate with everyone<br />

under much more scrut<strong>in</strong>y as to<br />

how <strong>the</strong>y use <strong>the</strong>ir time. More<br />

reliance will need to be on paid<br />

staff with appropriate<br />

pr<strong>of</strong>essional backgrounds. He<br />

also has a typically trenchant<br />

view on who is <strong>the</strong> audience <strong>of</strong><br />

IPEM. Of course <strong>the</strong> NHS is a<br />

major customer (I can hear<br />

Robert mutter four devolved<br />

NHS organisations) but we need<br />

to service a far broader<br />

congregation; academia, biology<br />

<strong>and</strong> related <strong>in</strong>dustries, perhaps<br />

even agriculture.<br />

Robert has served <strong>the</strong><br />

<strong>Institute</strong> well for <strong>the</strong> past 16<br />

years <strong>and</strong> even <strong>in</strong> his f<strong>in</strong>al<br />

months his enthusiasm for <strong>the</strong><br />

‘<br />

RETIREMENT<br />

Eight IPEM Presidents <strong>and</strong> <strong>the</strong> President-Elect had lunch with Robert Neilson <strong>in</strong> York to mark his retirement as General Secretary.<br />

Back row (left to right): Peter Sharp OBE (1997–99); Steve Smye (2001–03); Peter Wells CBE (1995–97); Peter Jackson (2005–07); Keith Ison<br />

(2007–09); Peter Williams (2003–05). Front row: Chris Gibson (2009–11); Peter Jarritt (2011–13); Robert Neilson (General Secretary,<br />

1996–2012); Steve Keevil (President-Elect, 2011–13). Rod Smallwood (1999–2001) was unable to attend at <strong>the</strong> last m<strong>in</strong>ute.<br />

work <strong>of</strong> <strong>the</strong> <strong>Institute</strong> is strong.<br />

We will miss his wise guidance,<br />

his hard work <strong>and</strong> his strategic<br />

vision. We will also miss his<br />

many anecdotes from his<br />

previous jobs! We wish him a<br />

long <strong>and</strong> productive retirement<br />

which he says he will spend<br />

br<strong>in</strong>g<strong>in</strong>g to fruition five books<br />

<strong>and</strong> f<strong>in</strong>ally trac<strong>in</strong>g his Scottish<br />

ancestry beyond a blank period<br />

<strong>in</strong> records, which he believes<br />

was caused by a ‘disruption’ <strong>in</strong><br />

<strong>the</strong> established, Scottish<br />

Presbyterian Church <strong>in</strong> St<br />

N<strong>in</strong>ians. He is amused, as a<br />

member <strong>of</strong> a church that had its<br />

orig<strong>in</strong>s <strong>in</strong> similar pr<strong>in</strong>cipled<br />

dissent from <strong>the</strong> 1662 Act <strong>of</strong><br />

Uniformity <strong>in</strong> Engl<strong>and</strong>, that his<br />

Scottish ancestors may<br />

<strong>the</strong>mselves have been <strong>in</strong>volved<br />

<strong>in</strong> <strong>the</strong> Scottish version <strong>of</strong> dissent<br />

<strong>in</strong> <strong>the</strong> 1700s.<br />

SCOPE | SEPTEMBER 2012 | 37


SCOPE | MEMBERS’ NEWS<br />

Pr<strong>of</strong>essor Peter Sharp OBE, FRSE, FIPEM, CSci, FInstP<br />

Robert Neilson pays tribute to <strong>the</strong> <strong>in</strong>credible work achieved <strong>in</strong> a long career<br />

Pr<strong>of</strong>essor Peter<br />

Sharp retired from<br />

his tw<strong>in</strong><br />

appo<strong>in</strong>tments as<br />

Pr<strong>of</strong>essor <strong>of</strong><br />

Medical <strong>Physics</strong> at <strong>the</strong><br />

University <strong>of</strong> Aberdeen <strong>and</strong><br />

Cl<strong>in</strong>ical Director <strong>of</strong> Medical<br />

<strong>Physics</strong> for NHS Grampian at<br />

<strong>the</strong> end <strong>of</strong> August 2012. He is<br />

one <strong>of</strong> a decreas<strong>in</strong>g number <strong>of</strong><br />

people with truly dual<br />

appo<strong>in</strong>tments, whose salary is<br />

paid by both <strong>the</strong> university <strong>and</strong><br />

<strong>the</strong> hospital. He observes that<br />

this means both employers<br />

expect him to do a full-time job<br />

for <strong>the</strong>m! He actually has found<br />

<strong>the</strong> arrangement very useful, as<br />

work<strong>in</strong>g with medical staff <strong>in</strong><br />

his NHS role has given him<br />

opportunities for spott<strong>in</strong>g<br />

research projects that he could<br />

carry out <strong>in</strong> his university role.<br />

EARLY CAREER<br />

Born <strong>in</strong> L<strong>in</strong>colnshire, <strong>and</strong> after<br />

a grammar school education <strong>in</strong><br />

Spald<strong>in</strong>g, Peter read <strong>Physics</strong> at<br />

Durham University <strong>and</strong> was<br />

awarded <strong>the</strong> degree <strong>of</strong> BSc<br />

(Hons) <strong>in</strong> 1968. Dur<strong>in</strong>g his f<strong>in</strong>al<br />

year he applied to Aberdeen for<br />

a place on <strong>the</strong> MSc <strong>in</strong> Medical<br />

<strong>Physics</strong> course developed by<br />

John Mallard OBE, who was <strong>the</strong><br />

first Pr<strong>of</strong>essor <strong>of</strong> Medical<br />

<strong>Physics</strong> at Aberdeen, <strong>and</strong> whom<br />

Peter would later succeed as<br />

<strong>the</strong> second Pr<strong>of</strong>essor. Peter<br />

decided his <strong>in</strong>terests really<br />

were <strong>in</strong> go<strong>in</strong>g on to do a PhD,<br />

<strong>and</strong> gave this as <strong>the</strong> reason for<br />

withdraw<strong>in</strong>g his application.<br />

John Mallard countered by<br />

<strong>of</strong>fer<strong>in</strong>g Peter a place as a PhD<br />

student to undertake research<br />

<strong>in</strong>to <strong>the</strong> quality <strong>of</strong> nuclear<br />

medic<strong>in</strong>e images, <strong>and</strong> <strong>the</strong> rest,<br />

as <strong>the</strong>y say, is history.<br />

When Peter had completed<br />

his PhD, he obta<strong>in</strong>ed a<br />

permanent appo<strong>in</strong>tment <strong>and</strong><br />

38 | SEPTEMBER 2012 | SCOPE<br />

stayed for <strong>the</strong> whole <strong>of</strong> his<br />

work<strong>in</strong>g life, eventually<br />

succeed<strong>in</strong>g John Mallard as<br />

Pr<strong>of</strong>essor <strong>of</strong> Medical <strong>Physics</strong><br />

when he retired.<br />

When asked why he had spent<br />

his entire career <strong>in</strong> Aberdeen, he<br />

said simply that <strong>the</strong>re was a lot <strong>of</strong><br />

<strong>in</strong>terest<strong>in</strong>g scientific work go<strong>in</strong>g<br />

on <strong>the</strong>re <strong>and</strong> he wanted to be part<br />

<strong>of</strong> it. In <strong>the</strong> early 1970s two SPECT<br />

“<br />

This means<br />

both employers<br />

expect him to do a<br />

full-time job for<br />

<strong>the</strong>m!<br />

”<br />

scanners were built, <strong>the</strong> first <strong>in</strong><br />

<strong>the</strong> UK <strong>and</strong> predat<strong>in</strong>g <strong>the</strong> x-ray CT<br />

scanner. Later, a gamma camera<br />

was mounted on <strong>the</strong> st<strong>and</strong> from<br />

an old cobalt mach<strong>in</strong>e to produce<br />

an early SPECT camera. In <strong>the</strong><br />

early 1980s Aberdeen developed<br />

<strong>the</strong> first cl<strong>in</strong>ical whole-body MR<br />

imager <strong>and</strong> established a PET<br />

centre <strong>in</strong> Aberdeen, <strong>the</strong> first <strong>in</strong> <strong>the</strong><br />

UK apart from <strong>the</strong> MRC PET<br />

Centre at Hammersmith<br />

Hospital. This <strong>in</strong>volved<br />

dismantl<strong>in</strong>g a cyclotron that had<br />

been used <strong>in</strong> a radio<strong>the</strong>rapy<br />

project <strong>in</strong> Ed<strong>in</strong>burgh, shipp<strong>in</strong>g it<br />

up to Aberdeen (courtesy <strong>of</strong> <strong>the</strong><br />

Army) <strong>and</strong> <strong>the</strong>n reassembl<strong>in</strong>g it.<br />

The Aberdeen PET centre also<br />

used a second-h<strong>and</strong> PET scanner<br />

that had previously been at <strong>the</strong><br />

Hammersmith PET centre.<br />

Initially <strong>the</strong>re was nowhere to put<br />

<strong>the</strong> equipment, so money had to<br />

be raised to buy an old farm<br />

build<strong>in</strong>g which was <strong>the</strong>n<br />

converted <strong>in</strong>to a PET centre with a<br />

radiochemistry facility. Peter<br />

remembers it as fun to see so<br />

much be<strong>in</strong>g achieved on a<br />

shoestr<strong>in</strong>g budget, although it<br />

didn’t seem like it at <strong>the</strong> time.<br />

PROFESSIONAL WORK<br />

Peter has spent most <strong>of</strong> his<br />

career work<strong>in</strong>g <strong>in</strong> nuclear<br />

medic<strong>in</strong>e, but when he succeeded<br />

John Mallard as Chair <strong>and</strong> as<br />

Head <strong>of</strong> Department <strong>in</strong> 1992, he<br />

rel<strong>in</strong>quished his role as Head <strong>of</strong><br />

Nuclear Medic<strong>in</strong>e, whilst<br />

reta<strong>in</strong><strong>in</strong>g a pr<strong>of</strong>essional <strong>in</strong>terest<br />

<strong>in</strong> <strong>the</strong> area. His cont<strong>in</strong>u<strong>in</strong>g<br />

<strong>in</strong>terest resulted <strong>in</strong> him<br />

persuad<strong>in</strong>g <strong>the</strong> hospital to pay for<br />

a new build<strong>in</strong>g for <strong>the</strong> PET centre<br />

to br<strong>in</strong>g it on to <strong>the</strong> hospital site,<br />

rais<strong>in</strong>g money for a new cyclotron<br />

<strong>and</strong> radiochemistry facility <strong>and</strong><br />

purchas<strong>in</strong>g a new PET imager. A<br />

few years later <strong>the</strong> Scottish<br />

Government wanted to know if<br />

PET was likely to be <strong>of</strong> value <strong>in</strong> <strong>the</strong><br />

management <strong>of</strong> cancer, <strong>and</strong><br />

Peter was asked to chair an<br />

advisory group to formulate<br />

advice. A model was constructed<br />

show<strong>in</strong>g how PET would be used<br />

<strong>in</strong> <strong>the</strong> cl<strong>in</strong>ical sett<strong>in</strong>g, <strong>and</strong><br />

populated with measures <strong>of</strong> <strong>the</strong><br />

sensitivity <strong>and</strong> specificity <strong>of</strong> PET<br />

for various cancers, to work out<br />

<strong>the</strong> likely costs <strong>of</strong> a PET service<br />

<strong>and</strong> <strong>the</strong>n demonstrate that it<br />

would be cost effective. The<br />

Scottish Government was<br />

persuaded that <strong>the</strong>y should <strong>in</strong>vest<br />

<strong>in</strong> PET scanners, which by this<br />

time were PET/CT scanners, <strong>and</strong><br />

equip <strong>the</strong> four cancer centres <strong>in</strong><br />

Scotl<strong>and</strong>. Peter was awarded <strong>the</strong><br />

Norman Veal Medal <strong>of</strong> <strong>the</strong> British<br />

Nuclear Medic<strong>in</strong>e Society <strong>in</strong> 1999<br />

<strong>in</strong> recognition <strong>of</strong> his contribution<br />

to nuclear medic<strong>in</strong>e.<br />

Away from nuclear medic<strong>in</strong>e,<br />

Peter’s research <strong>in</strong>terests had<br />

developed <strong>in</strong>to <strong>the</strong> science<br />

underp<strong>in</strong>n<strong>in</strong>g ophthalmology.<br />

There was a strong research<br />

group at Aberdeen University<br />

<strong>in</strong>terested <strong>in</strong> <strong>the</strong> biology <strong>of</strong><br />

diabetic eye disease, which is <strong>the</strong><br />

most common cause <strong>of</strong> bl<strong>in</strong>dness<br />

<strong>in</strong> <strong>the</strong> work<strong>in</strong>g age population.<br />

This group approached Peter’s<br />

physics team to see if <strong>the</strong>y could<br />

develop a scann<strong>in</strong>g laser<br />

ophthalmoscope. This was a<br />

device that scanned a laser beam<br />

over <strong>the</strong> ret<strong>in</strong>a <strong>of</strong> <strong>the</strong> eye <strong>and</strong> built<br />

up a picture from <strong>the</strong> reflected<br />

light. The team went fur<strong>the</strong>r <strong>and</strong><br />

built a mach<strong>in</strong>e that used three<br />

lasers at different wavelengths, to<br />

give a full colour, ra<strong>the</strong>r than<br />

monochromatic, image. It also<br />

went on to modify <strong>the</strong> scanner so<br />

that it would image <strong>in</strong>dividual<br />

blood cells as <strong>the</strong>y flowed<br />

through <strong>the</strong> ret<strong>in</strong>al vasculature <strong>in</strong><br />

rats <strong>and</strong> genetically modified<br />

mice. This allowed measurement<br />

<strong>of</strong> <strong>the</strong>ir speed <strong>and</strong> number <strong>of</strong><br />

cells, thus provid<strong>in</strong>g tools to<br />

<strong>in</strong>vestigate vascular diseases<br />

where it was believed that <strong>the</strong><br />

blood cells would stick to <strong>the</strong><br />

walls <strong>of</strong> <strong>the</strong> vessels.<br />

Peter’s team was <strong>the</strong>n<br />

approached by a group <strong>of</strong><br />

ophthalmologists who were<br />

runn<strong>in</strong>g a diabetic ret<strong>in</strong>al<br />

screen<strong>in</strong>g service <strong>in</strong> Scotl<strong>and</strong>.<br />

Every person <strong>in</strong> Scotl<strong>and</strong> with<br />

diabetes has annual images <strong>of</strong><br />

<strong>the</strong>ir eyes taken to look for early<br />

signs <strong>of</strong> eye disease. They were<br />

tra<strong>in</strong><strong>in</strong>g ret<strong>in</strong>al screeners to<br />

exam<strong>in</strong>e <strong>the</strong> tens <strong>of</strong> thous<strong>and</strong>s <strong>of</strong><br />

images <strong>and</strong> clearly it was<br />

extremely time consum<strong>in</strong>g,<br />

expensive <strong>and</strong> not very reliable.<br />

The physics team’s task was to<br />

develop s<strong>of</strong>tware that would<br />

analyse <strong>the</strong> ret<strong>in</strong>al images for <strong>the</strong><br />

pathology that was <strong>in</strong>dicative <strong>of</strong><br />

early eye disease. If none was<br />

found <strong>the</strong>n <strong>the</strong> person would<br />

simply be told to return <strong>the</strong> next<br />

year for ano<strong>the</strong>r picture. If <strong>the</strong>re<br />

were some abnormal features<br />

<strong>the</strong>n <strong>the</strong> images would be passed<br />

on to a human screener for<br />

fur<strong>the</strong>r analysis. The required<br />

s<strong>of</strong>tware was developed <strong>and</strong><br />

trialled with thous<strong>and</strong>s <strong>of</strong><br />

patients. The trials showed that it<br />

was reliable, <strong>and</strong> cheaper than


employ<strong>in</strong>g human screeners for<br />

basic screen<strong>in</strong>g. A licence on<br />

<strong>the</strong> s<strong>of</strong>tware was taken up by a<br />

company <strong>and</strong> <strong>the</strong> system is now<br />

<strong>in</strong> rout<strong>in</strong>e use <strong>in</strong> <strong>the</strong> Scottish<br />

Screen<strong>in</strong>g Service.<br />

HONOURS RECEIVED<br />

Research support<strong>in</strong>g<br />

ophthalmology cont<strong>in</strong>ues.<br />

Ano<strong>the</strong>r cl<strong>in</strong>ical trial<br />

concern<strong>in</strong>g automat<strong>in</strong>g<br />

macular oedema detection has<br />

just been completed; ano<strong>the</strong>r<br />

project is look<strong>in</strong>g at whe<strong>the</strong>r<br />

diabetic eye disease is a<br />

predictor <strong>of</strong> cardiovascular<br />

disease, <strong>and</strong> ano<strong>the</strong>r is look<strong>in</strong>g<br />

at <strong>the</strong> <strong>in</strong>formation that can be<br />

derived from serial ret<strong>in</strong>al<br />

photographs.<br />

In 2000 Peter’s department<br />

was awarded <strong>the</strong> Queen's<br />

Anniversary Prize for Higher<br />

<strong>and</strong> Fur<strong>the</strong>r Education <strong>in</strong><br />

recognition <strong>of</strong> its ‘pre-em<strong>in</strong>ence<br />

<strong>in</strong> medical imag<strong>in</strong>g technology<br />

for over 30 years’. As Peter had<br />

been <strong>the</strong>re for <strong>the</strong> entire 30<br />

years (<strong>and</strong> now 12 years more),<br />

this was not only a recognition<br />

<strong>of</strong> <strong>the</strong> work that <strong>the</strong> department<br />

had been do<strong>in</strong>g, it also reflected<br />

his contribution to it.<br />

But Peter’s work <strong>and</strong><br />

achievements must also be set<br />

<strong>in</strong> <strong>the</strong> context <strong>of</strong> his wider<br />

pr<strong>of</strong>essional contribution <strong>in</strong><br />

Scotl<strong>and</strong>, <strong>in</strong> <strong>the</strong> UK <strong>and</strong>, more<br />

recently, <strong>in</strong> Europe.<br />

Even as a PhD student,<br />

Peter’s research <strong>in</strong>volved<br />

contact with <strong>the</strong> NHS<br />

department <strong>in</strong> Aberdeen <strong>and</strong><br />

John Mallard quickly persuaded<br />

him to jo<strong>in</strong> HPA/IPSM,<br />

predecessor organisations <strong>of</strong><br />

IPEM. He recalled that an early<br />

<strong>in</strong>volvement <strong>in</strong> pr<strong>of</strong>essional<br />

body ‘corridors <strong>of</strong> power’ was<br />

when he attended a meet<strong>in</strong>g <strong>of</strong><br />

<strong>the</strong> IPSM Pr<strong>of</strong>essional<br />

Committee at <strong>the</strong> <strong>Institute</strong> <strong>of</strong><br />

<strong>Physics</strong>’ former <strong>of</strong>fices <strong>in</strong><br />

Belgrave Square, where <strong>the</strong><br />

HPA/IPSM <strong>of</strong>fice was <strong>the</strong>n hosted.<br />

Keith Boddy, who was to attend<br />

<strong>the</strong> meet<strong>in</strong>g, was delayed<br />

because he had been asked to<br />

meet with IOP <strong>of</strong>ficers, to be given<br />

<strong>the</strong> news that HPA /IPSM were<br />

be<strong>in</strong>g asked to f<strong>in</strong>d alternative<br />

<strong>of</strong>fice accommodation. It was<br />

decided to move to York, where<br />

IPEM (as it now is) now occupies<br />

its third <strong>of</strong>fice premises.<br />

Peter was <strong>the</strong> second IPEM<br />

President (1997–99), hav<strong>in</strong>g<br />

previously served as <strong>the</strong> first<br />

IPEM Vice President (1995–97)<br />

<strong>and</strong> <strong>the</strong> last Honorary Secretary<br />

<strong>of</strong> IPSM (1992–95), prior to which<br />

he was IPSM’s Assistant<br />

Honorary Secretary (1990–92).<br />

His reward for such dedicated<br />

service, post Presidency, was to<br />

be nom<strong>in</strong>ated by IPEM to be Chair<br />

<strong>of</strong> <strong>the</strong> Association <strong>of</strong> Cl<strong>in</strong>ical<br />

Scientists, to chair RPA 2000<br />

(which certificates Radiation<br />

Protection Advisers on behalf <strong>of</strong><br />

<strong>the</strong> Health <strong>and</strong> Safety Executive),<br />

to chair IPEM’s Pr<strong>of</strong>essional<br />

Conduct Committee, to represent<br />

IPEM on <strong>the</strong> Executive <strong>of</strong> <strong>the</strong><br />

IOP–IPEM Medical <strong>Physics</strong><br />

Group, to be Company Secretary<br />

<strong>of</strong> Radiation <strong>and</strong> Oncology<br />

Congresses, to represent IPEM<br />

on <strong>the</strong> Scottish Forum for<br />

Healthcare Science (which he<br />

also chaired), to be Honorary<br />

Treasurer <strong>of</strong> <strong>the</strong> (UK) Federation<br />

for Healthcare Science, to be<br />

Honorary Treasurer <strong>of</strong> <strong>the</strong><br />

European Federation <strong>of</strong><br />

Organisations for <strong>Physics</strong> <strong>in</strong><br />

Medic<strong>in</strong>e (EFOMP) <strong>and</strong> to be a<br />

member <strong>of</strong> <strong>the</strong> Science Council’s<br />

Registration Authority. Peter was<br />

elected as a Fellow <strong>of</strong> <strong>the</strong><br />

Royal Society <strong>of</strong> Ed<strong>in</strong>burgh<br />

(FRSE) <strong>and</strong> has served on<br />

its Council <strong>and</strong> its<br />

Fellowship Appo<strong>in</strong>tments<br />

Committee.<br />

‘<br />

OTHER INTERESTS<br />

As retirement (from employment,<br />

at least!) has drawn closer, Peter<br />

has managed to h<strong>and</strong> over most<br />

<strong>of</strong> his roles that had not already<br />

come to <strong>the</strong> end <strong>of</strong> a def<strong>in</strong>ed term<br />

<strong>of</strong> <strong>of</strong>fice. He rema<strong>in</strong>s a member <strong>of</strong><br />

<strong>the</strong> Science Council’s<br />

Registration Authority <strong>and</strong> <strong>in</strong><br />

January 2011 stood down after 5<br />

years as Honorary Treasurer to<br />

become Vice President <strong>of</strong> EFOMP,<br />

<strong>in</strong> <strong>the</strong> knowledge that he would<br />

succeed to <strong>the</strong> Presidency <strong>of</strong><br />

EFOMP from January 2012 for a<br />

term <strong>of</strong> 3 years.<br />

He confesses that he has ‘lived<br />

to work ra<strong>the</strong>r than worked to<br />

live’, but does f<strong>in</strong>d time for some<br />

<strong>in</strong>terests that are not workrelated.<br />

He chairs <strong>the</strong><br />

Adm<strong>in</strong>istration Board for <strong>the</strong><br />

Diocese <strong>of</strong> Brech<strong>in</strong> <strong>in</strong> <strong>the</strong> Scottish<br />

Episcopal Church. Several years<br />

ago he was appo<strong>in</strong>ted as an<br />

Honorary Sherriff, which <strong>in</strong> <strong>the</strong><br />

Scottish legal system is <strong>the</strong><br />

equivalent <strong>of</strong> a judge. However,<br />

while he has <strong>the</strong> power to give<br />

custodial sentences, he is not<br />

allowed to preside at trials by jury.<br />

Peter enjoys classical<br />

music,<br />

especially<br />

opera,<br />

<strong>and</strong><br />

believes<br />

that <strong>the</strong><br />

K<strong>in</strong>dle is<br />

one <strong>of</strong> <strong>the</strong><br />

most<br />

useful<br />

devices to<br />

have been<br />

developed<br />

RETIREMENT<br />

<strong>in</strong> <strong>the</strong> past 10 years. So, although<br />

it looks as if read<strong>in</strong>g is on his<br />

retirement agenda, erect<strong>in</strong>g more<br />

bookshelves is not!<br />

Over a long <strong>and</strong> successful<br />

career, Peter’s contribution to<br />

medical physics has been<br />

<strong>in</strong>calculable, even for a physicist<br />

or ma<strong>the</strong>matician, <strong>and</strong> IPEM <strong>and</strong><br />

<strong>the</strong> pr<strong>of</strong>ession <strong>in</strong> general <strong>in</strong> <strong>the</strong><br />

UK will be <strong>the</strong> poorer to lose his<br />

active presence. His outst<strong>and</strong><strong>in</strong>g<br />

contribution has, however,<br />

recently been recognised by <strong>the</strong><br />

award to him <strong>of</strong> an OBE <strong>in</strong> <strong>the</strong><br />

Queen’s Birthday Honours List,<br />

for services to healthcare<br />

science. However, with his<br />

retirement from employment, <strong>the</strong><br />

UK’s loss is Europe’s ga<strong>in</strong>, for a<br />

few more years at least, as he<br />

br<strong>in</strong>gs his accumulated wisdom<br />

to bear on medical physics<br />

matters European. Peter has also<br />

agreed to be <strong>the</strong> President <strong>of</strong><br />

ICMP 2013 (<strong>the</strong> International<br />

Congress <strong>of</strong> Medical <strong>Physics</strong>), to<br />

be hosted by IPEM <strong>in</strong> Brighton <strong>in</strong><br />

September 2013, <strong>and</strong> which will<br />

<strong>in</strong>corporate, with IOMP’s 50th<br />

anniversary congress, IPEM’s<br />

annual Medical <strong>Physics</strong> <strong>and</strong><br />

<strong>Eng<strong>in</strong>eer<strong>in</strong>g</strong> Conference<br />

(MPEC) <strong>and</strong> EFOMP’s<br />

biennial European<br />

Medical <strong>Physics</strong><br />

Congress (EMPC).<br />

So, as Peter retires<br />

from his career <strong>in</strong><br />

medical physics <strong>in</strong><br />

Aberdeen, for IPEM it<br />

will not be a complete<br />

‘goodbye’, but ‘au revoir’,<br />

<strong>and</strong> we wish him well <strong>in</strong><br />

his far-from-<strong>in</strong>active<br />

retirement.<br />

SCOPE | SEPTEMBER 2012 | 39


SCOPE | BOOK REVIEWS<br />

Welcome to ano<strong>the</strong>r<br />

issue <strong>of</strong> Scope<br />

‘Book Reviews’!<br />

This time around<br />

we have had <strong>the</strong><br />

highest number <strong>of</strong><br />

reviews submitted<br />

by our team <strong>of</strong> Ubidesk book reviewers. A<br />

special thanks to our reviewers who have,<br />

for <strong>the</strong> first time this year, supplied more<br />

than <strong>the</strong> target number <strong>of</strong> book reviews!<br />

Textbook reviews cover both <strong>the</strong> medical<br />

physics <strong>and</strong> popular science genres. A list<br />

<strong>of</strong> <strong>the</strong> reviewed titles with reviewers can be<br />

found below <strong>in</strong> table 1.<br />

As with each Scope issue, <strong>the</strong>re are a<br />

number <strong>of</strong> new medical physics textbooks<br />

<strong>in</strong> <strong>the</strong> ‘Just Published’ section. You will<br />

f<strong>in</strong>d some <strong>in</strong>terest<strong>in</strong>g reports listed <strong>in</strong> <strong>the</strong><br />

‘New Reports’ section, such as ‘Health<br />

Effects from Radi<strong>of</strong>requency<br />

Electromagnetic Fields’. I have <strong>in</strong>cluded a<br />

reference to a relatively recent report<br />

published by <strong>the</strong> Department <strong>of</strong> Health <strong>in</strong><br />

2011, ‘Radio<strong>the</strong>rapy Dataset Annual<br />

Report’, for completeness. You may also<br />

want to have a look at <strong>the</strong> ‘Safer<br />

Radio<strong>the</strong>rapy’ newsletter <strong>of</strong> <strong>the</strong> HPA, <strong>the</strong><br />

last <strong>of</strong> which was published <strong>in</strong> 2011 (issue<br />

6). Reader(s) who are <strong>in</strong>terested <strong>in</strong><br />

review<strong>in</strong>g listed/unlisted books please do<br />

get <strong>in</strong> touch with me so I can arrange to<br />

send you <strong>the</strong> required material directly<br />

from <strong>the</strong> publisher. Note that some <strong>of</strong> <strong>the</strong><br />

new reports are freely available to<br />

download from <strong>the</strong> respective websites.<br />

A warm welcome to ano<strong>the</strong>r book<br />

reviewer – Ms Rebecca Quest, Pr<strong>in</strong>cipal<br />

Cl<strong>in</strong>ical Scientist specialis<strong>in</strong>g <strong>in</strong> MRI <strong>and</strong><br />

work<strong>in</strong>g at <strong>the</strong> Imperial College Healthcare<br />

NHS Trust <strong>in</strong> London. Dr Mark McJury,<br />

Consultant Cl<strong>in</strong>ical Scientist, rejo<strong>in</strong>ed us<br />

after mov<strong>in</strong>g hospitals – he now works at<br />

<strong>the</strong> Beatson Cancer Centre as <strong>the</strong> Head <strong>of</strong><br />

Research <strong>and</strong> Development <strong>in</strong><br />

Radio<strong>the</strong>rapy <strong>Physics</strong>.<br />

We do require more book reviewers to<br />

allow us to consistently hit our 2012 target<br />

TABLE 1<br />

40 | SEPTEMBER 2012 | SCOPE<br />

<strong>of</strong> eight book reviews per quarter, so please<br />

drop me an email if you are <strong>in</strong>terested <strong>in</strong><br />

becom<strong>in</strong>g a reviewer. The review<strong>in</strong>g<br />

process is relatively relaxed, <strong>and</strong> <strong>the</strong>re are<br />

no tight deadl<strong>in</strong>es. If you are new to<br />

review<strong>in</strong>g, <strong>the</strong>n <strong>the</strong>re is a process<br />

document on f<strong>in</strong>d<strong>in</strong>g your way around<br />

Ubidesk as well as a guidance document<br />

on review<strong>in</strong>g textbooks.<br />

Usman I. Lula, Cl<strong>in</strong>ical Scientist, Radio<strong>the</strong>rapy<br />

<strong>Physics</strong>, Poole Hospital NHS Trust<br />

usman.lula@poole.nhs.uk<br />

Cardiac Fibrillation–<br />

Defibrillation<br />

This is an impressive book <strong>of</strong>fer<strong>in</strong>g a review<br />

<strong>of</strong> current biomedical concepts <strong>in</strong> atrial <strong>and</strong><br />

ventricular fibrillation – <strong>in</strong>itiation,<br />

ma<strong>in</strong>tenance, pharmacological <strong>the</strong>rapies <strong>and</strong><br />

eng<strong>in</strong>eer<strong>in</strong>g solutions for treatment are all<br />

given <strong>the</strong>ir due. Chapters cover fibrillation<br />

mechanisms, <strong>in</strong>clud<strong>in</strong>g <strong>the</strong> multiple ectopic<br />

foci, re-entry <strong>and</strong> rotor <strong>the</strong>ories <strong>of</strong><br />

fibrillation, as well as general concepts <strong>of</strong><br />

defibrillation (m<strong>in</strong>imum defibrillatory mass,<br />

pharmacological <strong>and</strong> electrical defibrillation,<br />

monophasic <strong>and</strong> biphasic DC shocks, etc.).<br />

The design <strong>and</strong> generic build <strong>of</strong> external<br />

defibrillators is discussed, as are algorithms<br />

that adjust delivered energy based on<br />

measures <strong>of</strong> transthoracic impedance.<br />

Implantable cardiac defibrillators (ICD) are<br />

passed over <strong>in</strong> brief, ma<strong>in</strong>ly <strong>in</strong> reference to<br />

s<strong>of</strong>tware methods to discrim<strong>in</strong>ate ventricular<br />

Book title Reviewer<br />

Cardiac Fibrillation–Defibrillation James Stirrup<br />

The Emperor <strong>of</strong> All Maladies Jennifer Lowe<br />

<strong>Physics</strong> <strong>of</strong> Societal Issues Malcolm Sperr<strong>in</strong><br />

The Fundamentals <strong>of</strong> Imag<strong>in</strong>g Lisa Davenport<br />

The Essential <strong>Physics</strong> <strong>of</strong> Medical Imag<strong>in</strong>g Elizabeth Berry<br />

Susceptibility Weighted Imag<strong>in</strong>g <strong>in</strong> MRI Glyn Coutts<br />

Biohybrid Systems Julie Wooldridge<br />

Quantitative MRI <strong>in</strong> Cancer John McLean<br />

Proton Therapy <strong>Physics</strong> Angela New<strong>in</strong>g<br />

tachycardia/fibrillation from normal or<br />

benign cardiac rhythms. From a personal<br />

perspective, this section was fasc<strong>in</strong>at<strong>in</strong>g<br />

given <strong>the</strong> cl<strong>in</strong>ical issues that can arise which<br />

necessitate device reprogramm<strong>in</strong>g to<br />

prevent <strong>in</strong>appropriate discharge. The real<br />

focus <strong>in</strong> this section though is on <strong>the</strong><br />

application <strong>of</strong> such s<strong>of</strong>tware to automated<br />

external defibrillators, which I suppose<br />

makes <strong>the</strong> book useful to any reader who<br />

regularly frequents large public spaces.<br />

Approaches to fibrillation detection are<br />

discussed <strong>in</strong> escalat<strong>in</strong>g order <strong>of</strong> complexity,<br />

from probability density functions <strong>and</strong><br />

threshold cross<strong>in</strong>g <strong>in</strong>tervals through to<br />

time-frequency Fourier techniques <strong>and</strong><br />

phase space analysis.<br />

The biggest sell<strong>in</strong>g po<strong>in</strong>t <strong>of</strong> <strong>the</strong> book is,<br />

to my m<strong>in</strong>d, <strong>the</strong> balance between <strong>the</strong> cl<strong>in</strong>ical<br />

<strong>and</strong> eng<strong>in</strong>eer<strong>in</strong>g content. As a cl<strong>in</strong>ician, I<br />

found <strong>the</strong> electrophysiology sections to be<br />

<strong>the</strong> most useful, but <strong>the</strong>re is plenty <strong>of</strong><br />

material to keep <strong>the</strong> eng<strong>in</strong>eer happy. There<br />

were sections that were harder go<strong>in</strong>g for me<br />

– I confess that <strong>the</strong> section on <strong>the</strong>oretical<br />

models went over my head (non-l<strong>in</strong>ear<br />

microscopic models <strong>of</strong> cardiac dynamics), as<br />

did <strong>the</strong> chapter on electrodes <strong>and</strong> pastes –<br />

but this is only really a reflection <strong>of</strong> <strong>the</strong><br />

multidiscipl<strong>in</strong>ary appeal <strong>of</strong> <strong>the</strong> book.<br />

Although now more than 16 months old<br />

(more consider<strong>in</strong>g <strong>the</strong> st<strong>and</strong>ard delay<br />

between submission <strong>and</strong> publication), this is<br />

a very readable account <strong>of</strong> current<br />

underst<strong>and</strong><strong>in</strong>g based on a broad analysis <strong>of</strong><br />

<strong>the</strong> field. I read <strong>the</strong> book from cover to cover<br />

over three W<strong>in</strong>chester–London tra<strong>in</strong> rides,<br />

which should give some idea <strong>of</strong> its length<br />

<strong>and</strong> easy accessibility. Like many textbooks<br />

purport<strong>in</strong>g to cover <strong>the</strong> current state-<strong>of</strong>-<strong>the</strong>art,<br />

<strong>the</strong>re is <strong>the</strong> significant danger <strong>of</strong> be<strong>in</strong>g<br />

out <strong>of</strong> date almost upon publication.<br />

Indeed, it is likely that those most <strong>in</strong>terested<br />

<strong>in</strong> this field will refra<strong>in</strong> from an outright<br />

purchase <strong>in</strong> favour <strong>of</strong> one or more journal<br />

subscriptions. This would be a shame as <strong>the</strong><br />

majority <strong>of</strong> <strong>the</strong> material discusses<br />

established concepts. I give this book a


confident recommendation to biomedical<br />

eng<strong>in</strong>eers, <strong>and</strong> for that matter, anyone for<br />

whom cardiac electrophysiology forms a<br />

significant part <strong>of</strong> <strong>the</strong>ir work<strong>in</strong>g life.<br />

Dr James Stirrup is a Cl<strong>in</strong>ical Research<br />

Fellow at <strong>the</strong> Cardiac Imag<strong>in</strong>g National Heart<br />

<strong>and</strong> Lung <strong>Institute</strong>, Imperial College, London.<br />

He is also a Cardiology Specialist Registrar at<br />

<strong>the</strong> Wessex Deanery, UK<br />

CARDIAC FIBRILLATION–DEFIBRILLATION:<br />

CLINICAL AND ENGINEERING ASPECTS –<br />

SERIES ON BIOENGINEERING AND BIOMEDICAL<br />

ENGINEERING<br />

Author: Max E. Valent<strong>in</strong>uzzi<br />

Publisher: World Scientific<br />

Volume: 6<br />

ISBN: 978-9814293631<br />

Pages: 304<br />

The Emperor <strong>of</strong> All<br />

Maladies<br />

I loved this book which was a slight relief<br />

as it would have been <strong>in</strong>terest<strong>in</strong>g to write a<br />

review <strong>in</strong> opposition to <strong>the</strong> many people<br />

who decided that this book was worthy <strong>of</strong><br />

a Pulitzer Prize (General Nonfiction, 2011),<br />

<strong>the</strong> Guardian First Book Award 2011 <strong>and</strong><br />

shortlisted for both <strong>the</strong> Duff Cooper Prize<br />

2011 <strong>and</strong> <strong>the</strong> Wellcome Trust Book Prize.<br />

The author, Siddhartha Mukherjee, is a<br />

well-published cancer physician <strong>and</strong><br />

researcher who lives <strong>in</strong> New York. He<br />

started research<strong>in</strong>g <strong>the</strong> history <strong>of</strong> cancer<br />

when he began his advanced tra<strong>in</strong><strong>in</strong>g <strong>in</strong><br />

medical oncology <strong>in</strong> Boston, which after<br />

about 7 years resulted <strong>in</strong> this book. The text<br />

follows a roughly chronological path<br />

through <strong>the</strong> history <strong>of</strong> cancer from its first<br />

description around 2500 BC <strong>in</strong> Egypt, to<br />

recent discoveries <strong>in</strong> <strong>the</strong> underst<strong>and</strong><strong>in</strong>g <strong>of</strong><br />

<strong>the</strong> activation or <strong>in</strong>activation <strong>of</strong> genes or<br />

pathways that result <strong>in</strong> cancer. The<br />

‘biography’ is also <strong>in</strong>terspersed with <strong>the</strong><br />

very human stories <strong>of</strong> a few <strong>of</strong> Mukherjee’s<br />

own patients <strong>and</strong> <strong>the</strong> successes <strong>and</strong> failures<br />

<strong>of</strong> <strong>the</strong>ir cancer treatments.<br />

The book is very well written, <strong>and</strong> <strong>in</strong><br />

spite <strong>of</strong> be<strong>in</strong>g packed with lots <strong>of</strong><br />

<strong>in</strong>terest<strong>in</strong>g facts <strong>and</strong> historical references, I<br />

found it to be a gripp<strong>in</strong>g read. I<br />

particularly liked how each <strong>the</strong>me was<br />

developed by pull<strong>in</strong>g toge<strong>the</strong>r different<br />

str<strong>and</strong>s from different researchers,<br />

hospitals <strong>and</strong> countries across <strong>the</strong> world.<br />

The ‘chapters’ are <strong>in</strong>troduced with a wide<br />

variety <strong>of</strong> quotations – historical, literary,<br />

<strong>and</strong> from contemporary media, activists,<br />

researchers <strong>and</strong> cancer patients which gave<br />

added <strong>in</strong>terest <strong>and</strong> context to <strong>the</strong> material.<br />

The book is predom<strong>in</strong>antly pla<strong>in</strong> text<br />

but <strong>in</strong> <strong>the</strong> middle section <strong>the</strong>re are eight<br />

pages <strong>of</strong> black-<strong>and</strong>-white photos, cartoons<br />

<strong>and</strong> draw<strong>in</strong>gs <strong>of</strong>fer<strong>in</strong>g, <strong>in</strong> my op<strong>in</strong>ion, a<br />

limited <strong>and</strong> r<strong>and</strong>om selection <strong>of</strong> pictures <strong>of</strong><br />

vary<strong>in</strong>g significance to cancer treatment. I<br />

did feel somewhat disappo<strong>in</strong>ted when <strong>the</strong><br />

book abruptly ended a significant distance<br />

from <strong>the</strong> back cover. However, for <strong>the</strong><br />

reader who wants to delve deeper, <strong>the</strong> 70<br />

or so pages <strong>of</strong> notes, references <strong>and</strong><br />

bibliography at <strong>the</strong> end <strong>of</strong> <strong>the</strong> book will be<br />

<strong>in</strong>valuable. A comprehensive <strong>in</strong>dex is also<br />

<strong>in</strong>cluded to facilitate return<strong>in</strong>g to passages<br />

<strong>of</strong> <strong>in</strong>terest.<br />

“<br />

The text follows a<br />

roughly chronological path<br />

through <strong>the</strong> history <strong>of</strong><br />

cancer from its first<br />

description around 2500<br />

BC <strong>in</strong> Egypt<br />

”<br />

I doubt that I will directly make use <strong>of</strong><br />

any knowledge ga<strong>in</strong>ed from this book <strong>in</strong><br />

my future radio<strong>the</strong>rapy work, but I feel<br />

that I am more <strong>in</strong>formed about <strong>the</strong> field <strong>in</strong><br />

general <strong>and</strong> will have a better appreciation<br />

<strong>of</strong> how far medic<strong>in</strong>e has come (<strong>and</strong> still has<br />

to go) <strong>in</strong> <strong>the</strong> treatment <strong>of</strong> cancer.<br />

Specifically I found it very <strong>in</strong>terest<strong>in</strong>g to<br />

see how cl<strong>in</strong>ical trials <strong>and</strong> r<strong>and</strong>omisation<br />

developed <strong>and</strong> learn<strong>in</strong>g <strong>of</strong> some <strong>of</strong> <strong>the</strong><br />

nam<strong>in</strong>g conventions for cancer drugs.<br />

I highly recommend this book to anyone<br />

with an <strong>in</strong>terest <strong>in</strong> medical history <strong>and</strong>/or<br />

who is work<strong>in</strong>g <strong>in</strong>, or close to, <strong>the</strong> field <strong>of</strong><br />

oncology. I found it to be highly<br />

<strong>in</strong>formative, a real page-turner <strong>and</strong> a<br />

welcome Christmas present. As <strong>the</strong><br />

paperback edition is currently available on<br />

Amazon.co.uk for a barga<strong>in</strong> price <strong>of</strong> £6.79,<br />

I th<strong>in</strong>k it would be rude not to.<br />

Mrs Jennifer Lowe is a Cl<strong>in</strong>ical Scientist<br />

(Radio<strong>the</strong>rapy) currently on a career break,<br />

Falls Church, VA, USA<br />

THE EMPEROR OF ALL MALADIES:<br />

A BIOGRAPHY OF CANCER<br />

Author: Siddhartha Mukherjee<br />

Publisher: HarperColl<strong>in</strong>s<br />

ISBN-13: 978-1439107959 (US)<br />

Format: Hardback<br />

Pages: 592<br />

USMAN I. LULA | SCOPE<br />

<strong>Physics</strong> <strong>of</strong> Societal<br />

Issues<br />

This title is not necessarily one that jumps<br />

<strong>of</strong>f <strong>the</strong> shelf at you as a prime text for<br />

medical physics applications, but I would<br />

strongly urge you to at least have a browse<br />

through it. One implication from <strong>the</strong> title is<br />

that <strong>the</strong> content is accessible to a lay public;<br />

however, I would suggest that <strong>the</strong> content<br />

does require a good deal <strong>of</strong> advanced<br />

scientific competence. The reviewed edition<br />

was published <strong>in</strong> 2007 <strong>and</strong> although only 5<br />

years old <strong>the</strong> implications <strong>of</strong> <strong>the</strong> Fukushima<br />

nuclear disaster clearly play no part <strong>in</strong> <strong>the</strong><br />

scientific analysis. That be<strong>in</strong>g said, it is an<br />

easy extrapolation <strong>of</strong> <strong>the</strong> book’s analysis to<br />

those events <strong>in</strong> Japan. This book looks to<br />

provide a well considered scientific<br />

approach to many <strong>of</strong> <strong>the</strong> <strong>in</strong>fluences on<br />

everyday life <strong>and</strong> <strong>the</strong>re is considerable<br />

cross-over with our pr<strong>of</strong>ession.<br />

The book is broadly divided <strong>in</strong>to:<br />

national security, environment <strong>and</strong> energy,<br />

but <strong>the</strong>se broad categories do not fully<br />

convey <strong>the</strong>ir content. For <strong>in</strong>stance, Chapter 7<br />

discusses nuclear pollution, albeit not from a<br />

medical st<strong>and</strong>po<strong>in</strong>t; never<strong>the</strong>less, <strong>the</strong><br />

analysis is applicable for those <strong>of</strong> us who<br />

have a pr<strong>of</strong>essional <strong>in</strong>terest <strong>in</strong> radiation<br />

protection. Similarly, Chapter 9 discusses<br />

electromagnetic fields <strong>and</strong> epidemiology<br />

which cont<strong>in</strong>ue to be very much <strong>in</strong> <strong>the</strong><br />

news. O<strong>the</strong>r chapters such as Chapter 16 on<br />

energy economics are reasonably considered<br />

to be peripheral to our pr<strong>of</strong>ession,<br />

none<strong>the</strong>less <strong>the</strong> analytical approach <strong>and</strong><br />

important subject matters are <strong>of</strong> general<br />

<strong>in</strong>terest. In addition, <strong>the</strong>re are useful<br />

appendices <strong>and</strong> reference/bibliography lists<br />

at <strong>the</strong> end <strong>of</strong> each chapter which, whilst<br />

limited, certa<strong>in</strong>ly do provide routes for more<br />

<strong>in</strong>sight <strong>in</strong>to some <strong>of</strong> <strong>the</strong> complex social<br />

arguments discussed with<strong>in</strong> <strong>the</strong> text.<br />

As might be expected, <strong>the</strong> text is<br />

American <strong>and</strong> allowances need to be made<br />

for <strong>the</strong> units <strong>and</strong> also some <strong>of</strong> <strong>the</strong> content<br />

which is American-centric, but that aside,<br />

<strong>the</strong> text is very readable. One useful aspect<br />

<strong>of</strong> each chapter is <strong>the</strong> <strong>in</strong>clusion <strong>of</strong> ‘problems’<br />

<strong>and</strong> I have used many <strong>of</strong> <strong>the</strong>se to discuss<br />

aspects <strong>of</strong> general physics with my tra<strong>in</strong>ees<br />

SCOPE | SEPTEMBER 2012 | 41<br />


▼<br />

SCOPE | BOOK REVIEWS<br />

<strong>and</strong> to encourage a breadth <strong>of</strong> awareness <strong>of</strong><br />

physics <strong>in</strong> addition to <strong>the</strong> specialist<br />

applications more familiar to us.<br />

To my knowledge <strong>the</strong>re are very few<br />

o<strong>the</strong>r books ei<strong>the</strong>r <strong>of</strong> this type or with <strong>the</strong><br />

same general usefulness, although <strong>the</strong><br />

Internet does give access to some <strong>of</strong> <strong>the</strong><br />

material albeit <strong>in</strong> a less consolidated form.<br />

Unfortunately, many <strong>of</strong> <strong>the</strong> diagrams <strong>and</strong><br />

images could be clearer but that is more <strong>of</strong> a<br />

convenience than a limit<strong>in</strong>g factor. I would<br />

highly recommend this text, probably as an<br />

<strong>in</strong>clusion to a departmental library ra<strong>the</strong>r<br />

than to an <strong>in</strong>dividual but I can see it be<strong>in</strong>g<br />

well used.<br />

Pr<strong>of</strong>essor Malcolm Sperr<strong>in</strong> is <strong>the</strong> Director <strong>of</strong><br />

Medical <strong>Physics</strong> <strong>and</strong> Cl<strong>in</strong>ical <strong>Eng<strong>in</strong>eer<strong>in</strong>g</strong> at <strong>the</strong><br />

Royal Berkshire Hospital NHS Trust, Read<strong>in</strong>g, UK<br />

PHYSICS OF SOCIETAL ISSUES: CALCULATIONS<br />

ON NATIONAL SECURITY, ENVIRONMENT, AND<br />

ENERGY<br />

Author: David Hafemeister<br />

Publisher: Spr<strong>in</strong>ger<br />

ISBN: 978-0-387-95560-5<br />

Pages: 488<br />

The Fundamentals <strong>of</strong><br />

Imag<strong>in</strong>g<br />

I was a bit worried that this book was go<strong>in</strong>g<br />

to be massive <strong>and</strong> maybe a bit dull. It<br />

encompasses, as <strong>the</strong> title suggests, almost<br />

all imag<strong>in</strong>g techniques, which is quite a big<br />

subject (especially everyth<strong>in</strong>g <strong>the</strong> author<br />

considers to be imag<strong>in</strong>g – more on that<br />

later) <strong>and</strong> potentially a hard slog for<br />

someone who doesn’t read physics books<br />

for fun (I’d just like to po<strong>in</strong>t that out now).<br />

However, not only is it compact, but it is<br />

also very easy to read <strong>and</strong> I even found it<br />

quite endear<strong>in</strong>g <strong>in</strong> parts.<br />

The author sets <strong>the</strong> scene by expla<strong>in</strong><strong>in</strong>g<br />

why sight is by far <strong>the</strong> best human sense<br />

before tell<strong>in</strong>g us about <strong>the</strong> human visual<br />

system <strong>and</strong> <strong>the</strong> evolution <strong>of</strong> all different<br />

eyes (I now know all about flatworm <strong>and</strong><br />

nautilus eyes if you have any questions).<br />

Then we embark on <strong>the</strong> proper physics<br />

sections. There is <strong>the</strong> obligatory bit on<br />

medical imag<strong>in</strong>g but that is only a t<strong>in</strong>y bit<br />

<strong>of</strong> a book that covers waves <strong>and</strong> image<br />

formation, microscopes, photography, film,<br />

42 | SEPTEMBER 2012 | SCOPE<br />

television, <strong>in</strong>frared imag<strong>in</strong>g, radar, imag<strong>in</strong>g<br />

<strong>the</strong> universe, imag<strong>in</strong>g with sound <strong>and</strong><br />

imag<strong>in</strong>g atoms <strong>and</strong> particles. As I<br />

mentioned at <strong>the</strong> beg<strong>in</strong>n<strong>in</strong>g, <strong>the</strong>re are a few<br />

bits I wasn’t sure about as to <strong>the</strong>ir imag<strong>in</strong>g<br />

credentials, but <strong>the</strong>y were some <strong>of</strong> my<br />

favourite bits: classical map mak<strong>in</strong>g, trig<br />

po<strong>in</strong>ts <strong>and</strong> aerial archaeology. Not that <strong>the</strong><br />

book isn’t up to date – 3D television <strong>and</strong><br />

imag<strong>in</strong>g <strong>the</strong> Eyjafjallajökull ash cloud are <strong>in</strong><br />

here too.<br />

The author’s writ<strong>in</strong>g style is friendly <strong>and</strong><br />

charm<strong>in</strong>g, <strong>and</strong> <strong>the</strong> book <strong>in</strong>cludes lots <strong>of</strong><br />

historical bits. The physics throughout are<br />

expla<strong>in</strong>ed simply with equations where<br />

need be <strong>and</strong> plenty <strong>of</strong> pictures <strong>and</strong><br />

diagrams.<br />

I would not recommend this book if you<br />

are look<strong>in</strong>g specifically for an <strong>in</strong>troduction<br />

to medical imag<strong>in</strong>g as <strong>the</strong> section is really<br />

brief. Likewise, I found <strong>the</strong> seismic imag<strong>in</strong>g<br />

section a bit short. On <strong>the</strong> o<strong>the</strong>r h<strong>and</strong>, <strong>the</strong><br />

universe sections seemed to take up quite a<br />

lot <strong>of</strong> <strong>the</strong> book, but I have to confess<br />

skipp<strong>in</strong>g those, hav<strong>in</strong>g managed to avoid<br />

anyth<strong>in</strong>g space-related <strong>in</strong> my life to date.<br />

However, <strong>the</strong> book is clearly <strong>in</strong>tended as a<br />

basic <strong>in</strong>troduction to everyth<strong>in</strong>g <strong>and</strong> for<br />

that it serves its purpose really well.<br />

As for <strong>the</strong> target audience, well, <strong>the</strong><br />

<strong>in</strong>troduction states that it should be<br />

accessible to those with an <strong>in</strong>terest <strong>in</strong><br />

science <strong>and</strong> who have studied it at school –<br />

I can only agree with that. It’s good for<br />

expla<strong>in</strong><strong>in</strong>g all those th<strong>in</strong>gs you (or at least I)<br />

never thought about before such as how an<br />

<strong>in</strong>truder alarm works.<br />

The book is clearly<br />

<strong>in</strong>tended as a basic<br />

<strong>in</strong>troduction to everyth<strong>in</strong>g<br />

<strong>and</strong> for that it serves its<br />

purpose really well<br />

“<br />

”<br />

In conclusion, I th<strong>in</strong>k that any physics<br />

book that mentions beluga whales <strong>and</strong><br />

Bradford Media Museum can only be a<br />

good th<strong>in</strong>g. And did you know that <strong>in</strong> 1880<br />

<strong>the</strong>y could detect <strong>the</strong> heat radiated by a cow<br />

at a distance <strong>of</strong> 400 m?<br />

Mrs Lisa Davenport is a Cl<strong>in</strong>ical Scientist <strong>in</strong><br />

Radiation Protection at <strong>the</strong> Radiation <strong>Physics</strong><br />

Department, Bradford Teach<strong>in</strong>g Hospitals NHS<br />

Foundation Trust, Bradford, UK<br />

THE FUNDAMENTALS OF IMAGING – FROM<br />

PARTICLES TO GALAXIES<br />

Author: Michael M. Woolfson<br />

Publisher: Imperial College Press<br />

ISBN: 9781848166851<br />

Format: Paperback<br />

Pages: 360<br />

Price: £32.00<br />

The Essential <strong>Physics</strong><br />

<strong>of</strong> Medical Imag<strong>in</strong>g<br />

This is <strong>the</strong> third edition <strong>of</strong> a well-respected<br />

text on <strong>the</strong> physics <strong>of</strong> medical imag<strong>in</strong>g. It<br />

covers all <strong>the</strong> expected imag<strong>in</strong>g modalities<br />

toge<strong>the</strong>r with radiation biology <strong>and</strong><br />

radiation protection. Although <strong>the</strong> earlier<br />

editions were <strong>in</strong>tended for radiologists-<strong>in</strong>tra<strong>in</strong><strong>in</strong>g,<br />

<strong>the</strong> comprehensive coverage made<br />

<strong>the</strong> book a popular graduate-level text for<br />

medical physicists too. In this third edition,<br />

<strong>the</strong> physicist readership has been recognised<br />

with <strong>the</strong> <strong>in</strong>clusion <strong>of</strong> an appendix on Fourier<br />

transforms <strong>and</strong> <strong>in</strong>creased ma<strong>the</strong>matical<br />

rigour throughout.<br />

The content <strong>of</strong> <strong>the</strong> book has been<br />

thoroughly overhauled. In l<strong>in</strong>e with <strong>the</strong><br />

spread <strong>of</strong> digital technologies, <strong>the</strong> section on<br />

<strong>in</strong>formatics has been moved <strong>in</strong>to <strong>the</strong> basic<br />

concepts section <strong>and</strong> has been exp<strong>and</strong>ed<br />

upon. There have been correspond<strong>in</strong>g<br />

reductions <strong>in</strong> <strong>the</strong> material on analogue<br />

techniques. Modalities that have entered<br />

cl<strong>in</strong>ical use s<strong>in</strong>ce <strong>the</strong> last edition, such as<br />

digital breast tomosyn<strong>the</strong>sis <strong>and</strong> dual<br />

modality imag<strong>in</strong>g systems, have now been<br />

<strong>in</strong>cluded.<br />

The book is surpris<strong>in</strong>gly colourful <strong>in</strong>side,<br />

not only giv<strong>in</strong>g it a contemporary feel, but<br />

also help<strong>in</strong>g to communicate <strong>in</strong>formation.<br />

There are coloured text head<strong>in</strong>gs, tables,<br />

photographs <strong>and</strong> figures. Many <strong>of</strong> <strong>the</strong><br />

figures have been redrawn for this edition,<br />

<strong>and</strong> with colour <strong>the</strong>y get <strong>the</strong>ir messages<br />

across very well <strong>in</strong>deed. Figures <strong>and</strong><br />

photographs have been brought up to date,<br />

show<strong>in</strong>g <strong>the</strong> thoroughness <strong>of</strong> <strong>the</strong> revisions.<br />

For example, a photo <strong>of</strong> a film badge<br />

belong<strong>in</strong>g to one <strong>of</strong> <strong>the</strong> authors now shows a<br />

badge dated 2011; <strong>the</strong> badge <strong>in</strong> <strong>the</strong> second<br />

edition was dated 2000.<br />

Ano<strong>the</strong>r <strong>in</strong>novation is <strong>the</strong> <strong>in</strong>clusion <strong>of</strong><br />

access to onl<strong>in</strong>e content. You scratch a sticker<br />

<strong>in</strong>side <strong>the</strong> book to reveal a code, visit <strong>the</strong><br />

publisher’s website <strong>and</strong> use <strong>the</strong> code to<br />

register. Once registered, you can access<br />

onl<strong>in</strong>e content – this comprises <strong>the</strong> entire<br />

content <strong>of</strong> <strong>the</strong> book, displayed <strong>in</strong> your<br />

browser us<strong>in</strong>g Adobe Flash Player<br />

technology format. The content is searchable<br />

<strong>and</strong>, for a book <strong>of</strong> this length, this provides a<br />

welcome alternative to us<strong>in</strong>g <strong>the</strong> <strong>in</strong>dex.


Books <strong>in</strong> this subject area can become<br />

somewhat unbalanced <strong>in</strong> <strong>the</strong>ir later<br />

editions, with ra<strong>the</strong>r short chapters on<br />

modalities such as ultrasound <strong>and</strong> MRI<br />

dom<strong>in</strong>ated by <strong>the</strong> ionis<strong>in</strong>g radiation<br />

content. Whilst this is true to a degree here,<br />

<strong>the</strong> balance <strong>in</strong> this book is good.<br />

Fur<strong>the</strong>rmore, <strong>in</strong> spite <strong>of</strong> <strong>the</strong> range <strong>of</strong> topics<br />

<strong>and</strong> multiple authors, <strong>the</strong> style is clear <strong>and</strong><br />

consistent throughout <strong>the</strong> book. This is very<br />

much a reference text, <strong>and</strong> does not <strong>in</strong>clude<br />

questions or exercises to help radiologists<br />

with <strong>the</strong>ir exam preparation. One concern<br />

about us<strong>in</strong>g this book outside <strong>the</strong> US is <strong>the</strong><br />

lack <strong>of</strong> <strong>in</strong>formation on European <strong>and</strong> more<br />

specifically UK legislation <strong>and</strong> regulation<br />

concern<strong>in</strong>g ionis<strong>in</strong>g radiation.<br />

The book is comprehensive,<br />

authoritative, well illustrated <strong>and</strong> bang up<br />

to date. It makes a suitable masters level<br />

textbook, <strong>and</strong> is an ideal reference text for<br />

<strong>the</strong> tra<strong>in</strong><strong>in</strong>g or practic<strong>in</strong>g medical physicist.<br />

It provides good value for money, <strong>and</strong><br />

owners <strong>of</strong> <strong>the</strong> second edition will not regret<br />

buy<strong>in</strong>g a replacement.<br />

Dr Elizabeth Berry <strong>of</strong> Elizabeth Berry Ltd <strong>in</strong><br />

Leeds, UK<br />

THE ESSENTIAL PHYSICS OF MEDICAL IMAGING,<br />

3RD EDITION – INTERNATIONAL EDITION<br />

Authors: Jerrold T. Bushberg, J. Anthony Seibert,<br />

Edw<strong>in</strong> M. Leidholdt Jr <strong>and</strong> John M. Boone<br />

Publisher: Lipp<strong>in</strong>cott Williams & Wilk<strong>in</strong>s<br />

ISBN: 9781451118100<br />

Format: Hardback<br />

Pages: 1,048<br />

Susceptibility<br />

Weighted Imag<strong>in</strong>g <strong>in</strong><br />

MRI<br />

‘Susceptibility weighted imag<strong>in</strong>g (SWI)<br />

consists <strong>of</strong> us<strong>in</strong>g both magnitude <strong>and</strong> phase<br />

images from a high-resolution threedimensional<br />

fully velocity compensated<br />

gradient echo sequence.’ The reader will<br />

encounter this sentence or similar many<br />

times <strong>in</strong> this text, followed by a brief<br />

description <strong>of</strong> <strong>the</strong> use <strong>of</strong> phase masks <strong>and</strong><br />

m<strong>in</strong>imum <strong>in</strong>tensity projections (mIP).<br />

However, this is merely a symptom <strong>of</strong> <strong>the</strong><br />

ambition <strong>of</strong> this volume <strong>in</strong> which 66<br />

contributors seek to cover every aspect <strong>of</strong><br />

fully exploit<strong>in</strong>g <strong>the</strong> phase <strong>in</strong>formation<br />

content <strong>in</strong> <strong>the</strong> acquired MR signal <strong>in</strong> a<br />

manner that is accessible to an audience <strong>of</strong><br />

radiologists, physicists, cardiologists,<br />

oncologists, biochemists <strong>and</strong> students.<br />

The first eight (arguably n<strong>in</strong>e) chapters<br />

(<strong>of</strong> Part I: ‘Basic Concepts’) serve as an<br />

<strong>in</strong>troduction to <strong>the</strong> technique, rang<strong>in</strong>g from<br />

what many will f<strong>in</strong>d familiar such as signal<br />

formation <strong>in</strong> gradient echo imag<strong>in</strong>g through<br />

to advanced but necessary concepts – for<br />

<strong>in</strong>stance, high-pass filter<strong>in</strong>g <strong>and</strong> <strong>the</strong><br />

<strong>in</strong>fluence <strong>of</strong> voxel aspect ratio – to <strong>the</strong> more<br />

daunt<strong>in</strong>g, such as <strong>the</strong> formation <strong>of</strong> phase<br />

images from multiple receiver coils. This<br />

<strong>the</strong>n leads <strong>in</strong>to <strong>the</strong> application <strong>of</strong> <strong>the</strong>se<br />

concepts to MR venography, with <strong>the</strong> by<br />

now familiar high-resolution, high-contrast<br />

images, <strong>and</strong> bra<strong>in</strong> imag<strong>in</strong>g.<br />

Part II covers current cl<strong>in</strong>ical applications<br />

<strong>and</strong> may well be <strong>the</strong> start<strong>in</strong>g po<strong>in</strong>t for those<br />

just beg<strong>in</strong>n<strong>in</strong>g to use this technique.<br />

Included are vascular applications along<br />

with imag<strong>in</strong>g cerebral microbleeds <strong>and</strong><br />

haemorrhage, imag<strong>in</strong>g <strong>of</strong> bra<strong>in</strong> tumours,<br />

exploit<strong>in</strong>g iron content <strong>in</strong><br />

neurodegenerative disease <strong>and</strong> imag<strong>in</strong>g <strong>of</strong><br />

breast calcification. The book <strong>in</strong>cludes<br />

repr<strong>in</strong>ts <strong>of</strong> three sem<strong>in</strong>al papers published<br />

<strong>in</strong> 1997, 2004 <strong>and</strong> 2006, but it is a mark <strong>of</strong><br />

how much this technique is <strong>in</strong> its <strong>in</strong>fancy <strong>in</strong><br />

that much <strong>of</strong> <strong>the</strong> work presented here is<br />

based on relatively small studies from<br />

s<strong>in</strong>gle research centres.<br />

The f<strong>in</strong>al chapter <strong>in</strong> Part II <strong>in</strong>troduces<br />

SWI at ultrahigh field strengths (7T or even<br />

9.4T) with a balanced summary <strong>of</strong> both <strong>the</strong><br />

opportunities <strong>and</strong> challenges. The last <strong>and</strong><br />

largest section, Part III, is headed<br />

‘Advanced Concepts’ <strong>and</strong> ranges across<br />

applications which may well bear fruit for<br />

SWI, such as quantification <strong>of</strong> iron content,<br />

<strong>the</strong> effects <strong>of</strong> contrast agents, quantification<br />

<strong>of</strong> oxygen saturation <strong>and</strong> <strong>the</strong> <strong>in</strong>terplay with<br />

<strong>the</strong> BOLD effect, as well as advanced<br />

acquisition methods. Also discussed <strong>in</strong><br />

<strong>the</strong>se chapters is susceptibility mapp<strong>in</strong>g<br />

which effectively <strong>in</strong>verts <strong>the</strong> problem <strong>in</strong><br />

order to produce maps <strong>of</strong> <strong>the</strong> susceptibility<br />

sources that are produc<strong>in</strong>g <strong>the</strong> measured<br />

phase patterns, with <strong>the</strong> aim <strong>of</strong> produc<strong>in</strong>g<br />

quantitative <strong>in</strong>formation about, say, <strong>the</strong> iron<br />

or calcium content <strong>of</strong> tissues.<br />

There is <strong>in</strong>evitably some variation <strong>in</strong><br />

style across <strong>the</strong> many contributors but for a<br />

work <strong>of</strong> this size <strong>and</strong> scope <strong>the</strong> errors <strong>of</strong><br />

grammar, presentation <strong>and</strong> suchlike are<br />

relatively few. Throughout, <strong>the</strong> text is<br />

supported well by <strong>the</strong> images, <strong>in</strong>clud<strong>in</strong>g<br />

colour images where needed.<br />

It will be <strong>of</strong> <strong>in</strong>terest <strong>in</strong> a few years’ time<br />

to see how much progress has been made <strong>in</strong><br />

fully exploit<strong>in</strong>g susceptibility differences as<br />

a basis for (quantitative) MR imag<strong>in</strong>g. For<br />

USMAN I. LULA | SCOPE<br />

now this volume will be a useful reference<br />

for any MRI department.<br />

Dr Glyn Coutts is a Cl<strong>in</strong>ical Scientist at <strong>the</strong><br />

Christie Medical <strong>Physics</strong> <strong>and</strong> <strong>Eng<strong>in</strong>eer<strong>in</strong>g</strong>, The<br />

Christie NHS Foundation Trust, Manchester<br />

Department, UK<br />

SUSCEPTIBILITY WEIGHTED IMAGING IN MRI<br />

Editors: E. Mark Haacke <strong>and</strong> Jürgen R.<br />

Reichenbach<br />

Publisher: Wiley-Blackwell<br />

ISBN: 978-0-470-04343-1<br />

Format: Hardback<br />

Pages: 776<br />

Biohybrid Systems<br />

This text <strong>of</strong>fers a detailed overview <strong>of</strong> recent<br />

advances <strong>in</strong> biohybrid systems <strong>in</strong>terfac<strong>in</strong>g<br />

nerves, muscles <strong>and</strong> mach<strong>in</strong>es. It conta<strong>in</strong>s<br />

numerous ma<strong>the</strong>matical models <strong>of</strong><br />

neurophysiology, rang<strong>in</strong>g from models <strong>of</strong> <strong>the</strong><br />

cell biology such as membrane equivalent<br />

circuits to <strong>the</strong> ma<strong>the</strong>matical descriptions <strong>of</strong><br />

neural spike tra<strong>in</strong>s. The text also considers<br />

<strong>the</strong> hardware required to <strong>in</strong>terface with a<br />

neuron, <strong>in</strong> particular <strong>the</strong> dynamic clamp<br />

which is used to <strong>in</strong>fluence membrane<br />

potentials <strong>and</strong> <strong>the</strong> latest nanotransducers,<br />

be<strong>in</strong>g developed us<strong>in</strong>g carbon nanotubes.<br />

This book is primarily aimed at researchers<br />

<strong>in</strong> <strong>the</strong> field with recommendations on <strong>the</strong><br />

best s<strong>of</strong>tware for implement<strong>in</strong>g a dynamic<br />

clamp <strong>and</strong> suppliers <strong>of</strong> real-time control<br />

boards for neuronal models.<br />

Each chapter commences with a short<br />

<strong>in</strong>troduction, plac<strong>in</strong>g <strong>the</strong> subject matter <strong>in</strong>to<br />

context with <strong>the</strong> o<strong>the</strong>r chapters. Each also<br />

closes with a conclusion which generally<br />

does a good job <strong>of</strong> summ<strong>in</strong>g up <strong>the</strong> salient<br />

po<strong>in</strong>ts <strong>of</strong> <strong>the</strong> text, particularly useful for <strong>the</strong><br />

first-time reader. Much <strong>of</strong> <strong>the</strong> modell<strong>in</strong>g<br />

assumes a high level <strong>of</strong> background<br />

knowledge <strong>in</strong> ma<strong>the</strong>matics, electronics <strong>and</strong><br />

neuroscience. This should probably not be<br />

considered an <strong>in</strong>troductory text; however,<br />

even <strong>the</strong> casual reader will come away with<br />

an enhanced underst<strong>and</strong><strong>in</strong>g <strong>of</strong> <strong>the</strong> field.<br />

The chapters are well written <strong>and</strong> despite<br />

be<strong>in</strong>g a multi-authored work <strong>the</strong>re is little<br />

repetition <strong>and</strong> appropriate l<strong>in</strong>ks to o<strong>the</strong>r<br />

sections are provided. There are a good<br />

number <strong>of</strong> illustrations, most <strong>of</strong> which are ▼<br />

SCOPE | SEPTEMBER 2012 | 43


▼<br />

SCOPE | BOOK REVIEWS<br />

very useful, <strong>in</strong> particular <strong>in</strong> Chapter 6 with<br />

its scann<strong>in</strong>g electron micrographs <strong>of</strong><br />

microelectrode arrays <strong>and</strong> Chapter 7 with<br />

numerous Simul<strong>in</strong>k diagrams provid<strong>in</strong>g<br />

excellent support to an <strong>in</strong>troduction <strong>of</strong><br />

biohybrid systems analysis.<br />

The medical physicist<br />

will f<strong>in</strong>d little description<br />

<strong>of</strong> <strong>the</strong> practical<br />

applications <strong>of</strong> this<br />

technology until <strong>the</strong> last<br />

three chapters<br />

“<br />

”<br />

Aside from a very <strong>in</strong>terest<strong>in</strong>g short<br />

section <strong>in</strong> <strong>the</strong> first chapter on an actuated<br />

articulated false-foot orthosis (designed to<br />

aid crutch-free walk<strong>in</strong>g for <strong>in</strong>jured combat<br />

troops), <strong>the</strong> medical physicist will f<strong>in</strong>d<br />

little description <strong>of</strong> <strong>the</strong> practical<br />

applications <strong>of</strong> this technology until <strong>the</strong><br />

last three chapters. This makes some <strong>of</strong> <strong>the</strong><br />

<strong>in</strong>terven<strong>in</strong>g chapters ra<strong>the</strong>r ‘dry’ <strong>and</strong> it’s a<br />

shame that more short examples <strong>of</strong> <strong>the</strong><br />

applications weren’t <strong>in</strong>cluded. The last<br />

part <strong>of</strong> <strong>the</strong> book is dedicated to a few<br />

examples <strong>of</strong> medical applications,<br />

<strong>in</strong>clud<strong>in</strong>g neuromorphic hardware for<br />

audition <strong>and</strong> vision, neurocardiology <strong>and</strong><br />

sens<strong>in</strong>g <strong>of</strong> <strong>in</strong>sul<strong>in</strong> dem<strong>and</strong>. This is where<br />

<strong>the</strong> readers’ hard work <strong>in</strong> <strong>the</strong> earlier<br />

chapters will pay <strong>of</strong>f! Chapter 9,<br />

‘Neuromorphic Hardware for Control’, is<br />

particularly <strong>in</strong>terest<strong>in</strong>g, demonstrat<strong>in</strong>g a<br />

biohybrid system to restore lost locomotor<br />

control <strong>and</strong> a silicon ret<strong>in</strong>a <strong>in</strong> which spatial<br />

<strong>and</strong> temporal filter<strong>in</strong>g are computed at<br />

pixel level allow<strong>in</strong>g low-power real-time<br />

control <strong>of</strong> a system.<br />

As a research text, this book will f<strong>in</strong>d<br />

little immediate application <strong>in</strong> <strong>the</strong> majority<br />

<strong>of</strong> cl<strong>in</strong>ical eng<strong>in</strong>eer<strong>in</strong>g departments. Many<br />

<strong>of</strong> <strong>the</strong> systems demonstrated will be<br />

conf<strong>in</strong>ed to studies <strong>in</strong> research laboratories<br />

for some time to come. However, for<br />

anyone <strong>in</strong>trigued by <strong>the</strong> latest<br />

neuropros<strong>the</strong>ses showcased <strong>in</strong> <strong>the</strong> news or<br />

nature, this publication <strong>of</strong>fers a fasc<strong>in</strong>at<strong>in</strong>g<br />

<strong>in</strong>sight <strong>in</strong>to <strong>the</strong> field.<br />

Ms Julie Wooldridge is a Tra<strong>in</strong>ee Cl<strong>in</strong>ical<br />

Scientist <strong>in</strong> Electrodiagnostics <strong>and</strong> Cl<strong>in</strong>ical<br />

<strong>Eng<strong>in</strong>eer<strong>in</strong>g</strong> at <strong>the</strong> University Hospitals <strong>of</strong><br />

Leicester NHS Trust, UK<br />

BIOHYBRID SYSTEMS: NERVES, INTERFACES<br />

AND MACHINES<br />

Editor: Ranu Jung<br />

Publisher: Wiley-VCH<br />

ISBN: 9783527409495<br />

Format: Hardback<br />

Pages: 224<br />

44 | SEPTEMBER 2012 | SCOPE<br />

Quantitative MRI <strong>in</strong><br />

Cancer<br />

I was keen to review this book as I have an<br />

<strong>in</strong>terest <strong>in</strong> QMRI methods. Probably <strong>the</strong><br />

most comprehensive book to date on this<br />

topic is <strong>the</strong> QMRI <strong>in</strong> <strong>the</strong> bra<strong>in</strong> book by Paul<br />

T<strong>of</strong>ts. However, it has been several years<br />

s<strong>in</strong>ce it was published <strong>and</strong> I was <strong>in</strong>terested<br />

to see how o<strong>the</strong>rs presented <strong>the</strong>se <strong>the</strong>mes.<br />

The unique sell<strong>in</strong>g po<strong>in</strong>t <strong>of</strong> this new book<br />

is its focus on <strong>the</strong> application <strong>of</strong> QMRI<br />

methods <strong>in</strong> <strong>the</strong> treatment <strong>of</strong> cancer. This<br />

book provides a focussed, disease-led<br />

approach to present<strong>in</strong>g QMRI methods. This<br />

reflects <strong>the</strong> target audience, who <strong>in</strong> this case<br />

is likely to be researchers <strong>and</strong> cl<strong>in</strong>icians with<br />

an <strong>in</strong>terest <strong>in</strong> <strong>the</strong> application <strong>of</strong> novel<br />

imag<strong>in</strong>g methods to cancer.<br />

A fur<strong>the</strong>r feature <strong>of</strong> this textbook is that it<br />

does not focus solely on <strong>the</strong> bra<strong>in</strong> by<br />

cover<strong>in</strong>g QMRI techniques applied to a<br />

range <strong>of</strong> o<strong>the</strong>r areas <strong>of</strong> <strong>the</strong> body such as <strong>the</strong><br />

breast <strong>and</strong> prostate.<br />

The book itself is structured <strong>in</strong>to five<br />

sections, namely: ‘The Physical Basis <strong>of</strong><br />

MRI’; ‘Characteris<strong>in</strong>g Tissue Properties with<br />

Endogenous Contrast Mechanisms’;<br />

‘Characteris<strong>in</strong>g Tissue Properties with<br />

Exogenous Contrast Mechanisms’, <strong>and</strong><br />

end<strong>in</strong>g with ‘Image Process<strong>in</strong>g <strong>in</strong> Cancer<br />

<strong>and</strong> Emerg<strong>in</strong>g Trends’.<br />

The <strong>in</strong>troductory chapters on <strong>the</strong> biology<br />

<strong>and</strong> imag<strong>in</strong>g <strong>of</strong> cancer set <strong>the</strong> scene for <strong>the</strong><br />

rest <strong>of</strong> <strong>the</strong> book. The chapters on <strong>the</strong> physics<br />

<strong>of</strong> MRI <strong>and</strong> <strong>in</strong> particular <strong>the</strong> chapter on<br />

hardware <strong>and</strong> data acquisition are some <strong>of</strong><br />

<strong>the</strong> best I’ve seen where <strong>the</strong> text is well<br />

supported by clear figures <strong>and</strong> equations.<br />

Beyond <strong>the</strong> <strong>in</strong>troductory chapters <strong>of</strong> <strong>the</strong><br />

book <strong>the</strong> QMRI methods beg<strong>in</strong> to be<br />

<strong>in</strong>troduced. Many <strong>of</strong> <strong>the</strong> chapters follow <strong>the</strong><br />

structure <strong>of</strong> hav<strong>in</strong>g both quantitative <strong>and</strong><br />

<strong>the</strong>n qualitative descriptions. This makes <strong>the</strong><br />

book accessible to readers who may just<br />

want an overview <strong>of</strong> <strong>the</strong> topic as well as<br />

provid<strong>in</strong>g more detailed quantitative <strong>and</strong><br />

ma<strong>the</strong>matical descriptions for those who<br />

may wish to try <strong>and</strong> implement or develop<br />

<strong>the</strong> methods for <strong>the</strong>mselves.<br />

The structure <strong>and</strong> choice <strong>of</strong> sections <strong>of</strong> <strong>the</strong><br />

book are sensible <strong>and</strong> <strong>the</strong>re is an entire<br />

section (five chapters) devoted to image<br />

process<strong>in</strong>g methods <strong>in</strong> cancer. This reflects<br />

<strong>the</strong> importance <strong>of</strong> modern image process<strong>in</strong>g<br />

methods <strong>in</strong> facilitat<strong>in</strong>g quantitative<br />

methods. The <strong>in</strong>dividual chapters conta<strong>in</strong><br />

<strong>the</strong> essential descriptions <strong>and</strong> underly<strong>in</strong>g<br />

ma<strong>the</strong>matics for each <strong>of</strong> <strong>the</strong> topics.<br />

Throughout this book each chapter is well<br />

referenced <strong>and</strong> importantly <strong>the</strong> authors<br />

direct <strong>the</strong> reader to associated s<strong>of</strong>tware tools<br />

that have been used to perform image<br />

process<strong>in</strong>g tasks.<br />

The f<strong>in</strong>al section <strong>of</strong> <strong>the</strong> book <strong>in</strong>troduces<br />

emerg<strong>in</strong>g trends <strong>of</strong> QMRI <strong>in</strong> cancer. These<br />

are <strong>the</strong> use <strong>of</strong> MRI <strong>in</strong> radiation <strong>the</strong>rapy;<br />

molecular <strong>and</strong> cellular imag<strong>in</strong>g <strong>and</strong> <strong>the</strong> use<br />

<strong>of</strong> hyperpolarised MR <strong>in</strong> cancer. These topics<br />

are excit<strong>in</strong>g <strong>and</strong> it is right that <strong>the</strong>y have<br />

been <strong>in</strong>cluded <strong>in</strong> a text such as this to enable<br />

<strong>the</strong> reader to get <strong>the</strong> best perspective on <strong>the</strong><br />

current status <strong>of</strong> active research <strong>in</strong> this<br />

particular field.<br />

Overall, this is an excellent book for<br />

anyone <strong>in</strong>terested <strong>in</strong> <strong>the</strong> application <strong>of</strong><br />

QMRI methods ‘to cancer’. This textbook<br />

would also be useful for anyone <strong>in</strong>terested<br />

<strong>in</strong> QMRI methods, irrespective <strong>of</strong> <strong>the</strong>ir<br />

disease <strong>of</strong> <strong>in</strong>terest.<br />

Dr John McLean is a Cl<strong>in</strong>ical Scientist <strong>in</strong><br />

Neuroradiology at <strong>the</strong> <strong>Institute</strong> <strong>of</strong> Neurological<br />

Sciences, Glasgow, Scotl<strong>and</strong>, UK<br />

QUANTITATIVE MRI IN CANCER<br />

Editors: T. Yankeelov, D. Pickens <strong>and</strong> R. Price<br />

Publisher: CRC Press (Taylor & Francis)<br />

ISBN: 9781439820575<br />

Format: Hardback<br />

Pages: 338<br />

Proton Therapy<br />

<strong>Physics</strong><br />

Did you know that <strong>the</strong> possibility <strong>of</strong> us<strong>in</strong>g<br />

protons <strong>in</strong> radio<strong>the</strong>rapy was first postulated<br />

as long ago as 1946 by R. R.Wilson at<br />

Harvard University? He suggested that <strong>the</strong><br />

f<strong>in</strong>ite range <strong>and</strong> Bragg peak <strong>of</strong> proton beams<br />

could be used to treat deep targets <strong>in</strong> <strong>the</strong><br />

body with m<strong>in</strong>imal damage to normal<br />

tissue. The idea was taken up a few years<br />

later by Tobias <strong>and</strong> his colleagues at<br />

Berkeley Laboratories <strong>in</strong> California <strong>and</strong> <strong>the</strong>


first small group <strong>of</strong> patients was treated<br />

<strong>the</strong>re <strong>in</strong> 1954.<br />

This was a revelation to me <strong>and</strong>, I<br />

imag<strong>in</strong>e, to most readers <strong>of</strong> Scope today. In<br />

<strong>the</strong> UK at Clatterbridge, protons have been<br />

used to treat ocular tumours, with good<br />

results, s<strong>in</strong>ce 1989. Worldwide, many<br />

different sites have been treated s<strong>in</strong>ce <strong>the</strong><br />

1970s, with Russia <strong>and</strong> Japan lead<strong>in</strong>g <strong>in</strong><br />

contention with <strong>the</strong> United States. There<br />

has been an exponential rise <strong>in</strong> <strong>in</strong>terest<br />

over <strong>the</strong> last 30 years as demonstrated by<br />

<strong>the</strong> rise <strong>in</strong> papers <strong>in</strong> peer-reviewed<br />

journals. From one or two <strong>in</strong> 1980, <strong>the</strong>re<br />

were almost 150 <strong>in</strong> 2010. You will f<strong>in</strong>d all<br />

this <strong>in</strong> Chapter 1 <strong>of</strong> this amaz<strong>in</strong>g book.<br />

There are 22 contributors, mostly<br />

American physicists, but with <strong>in</strong>put from<br />

Germany, Switzerl<strong>and</strong>, NPL (UK) <strong>and</strong> <strong>the</strong><br />

Ne<strong>the</strong>rl<strong>and</strong>s. The editor, who provides<br />

several chapters himself, is <strong>of</strong> German<br />

orig<strong>in</strong> but has been <strong>the</strong> Director <strong>of</strong> <strong>Physics</strong><br />

Research <strong>in</strong> Boston, Massachusetts, for<br />

some years.<br />

The basic physics is thoroughly<br />

explored <strong>in</strong> <strong>the</strong> 60 pages <strong>of</strong> Chapter 2.<br />

Cyclotrons, synchrotrons <strong>and</strong> accelerator<br />

technologies are dealt with <strong>in</strong> Chapter 3,<br />

followed by several chapters on cl<strong>in</strong>ical<br />

uses, dosimetry <strong>and</strong> treatment plann<strong>in</strong>g.<br />

There is comprehensive coverage <strong>of</strong> all<br />

aspects <strong>of</strong> proton radio<strong>the</strong>rapy here, set out<br />

<strong>in</strong> a concise manner for readers who have a<br />

good knowledge <strong>of</strong> physics to start with.<br />

“<br />

Did you know that <strong>the</strong><br />

possibility <strong>of</strong> us<strong>in</strong>g protons<br />

<strong>in</strong> radio<strong>the</strong>rapy was first<br />

postulated as long ago as<br />

1946?<br />

”<br />

I th<strong>in</strong>k that this book will be an<br />

<strong>in</strong>dispensable aid for physicists beg<strong>in</strong>n<strong>in</strong>g<br />

to work <strong>in</strong> <strong>the</strong> area <strong>of</strong> proton <strong>the</strong>rapy <strong>and</strong> I<br />

have no hesitation <strong>in</strong> recommend<strong>in</strong>g it.<br />

The future <strong>of</strong> radio<strong>the</strong>rapy depends<br />

upon precise beam shap<strong>in</strong>g <strong>and</strong> be<strong>in</strong>g able<br />

to use <strong>the</strong> distal fall <strong>of</strong>f <strong>in</strong> dose due to f<strong>in</strong>ite<br />

beam range.<br />

Pr<strong>of</strong>essor Angela New<strong>in</strong>g is a Retired<br />

Director <strong>of</strong> Medical <strong>Physics</strong> for<br />

Gloucestershire, UK<br />

PROTON THERAPY PHYSICS (SERIES IN<br />

MEDICAL PHYSICS AND BIOMEDICAL<br />

ENGINEERING)<br />

Editor: Harald Paganetti<br />

Publisher: CRC Press (Taylor & Francis)<br />

ISBN: 9781439836446<br />

Format: Hardback<br />

Pages: 704<br />

Just Published!<br />

Electrical Safety H<strong>and</strong>book by John Cadick,<br />

Mary Capelli-Schellpfeffer, Al W<strong>in</strong>field <strong>and</strong><br />

Dennis K. Neitzel (McGraw-Hill) is an<br />

essential, fully updated on-<strong>the</strong>-job safety<br />

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electrical construction safety <strong>and</strong> medic<strong>in</strong>e<br />

as a practical guide for electrical workers<br />

<strong>and</strong> o<strong>the</strong>rs exposed to electrical hazards.<br />

Biomedical Signals <strong>and</strong> Sensors I by<br />

Eugenijus Kaniusas (Spr<strong>in</strong>ger) focuses on <strong>the</strong><br />

<strong>in</strong>terface between physiologic mechanisms<br />

<strong>and</strong> diagnostic human eng<strong>in</strong>eer<strong>in</strong>g. This is<br />

<strong>the</strong> first part <strong>of</strong> a two-volume set <strong>and</strong> this<br />

volume describes <strong>the</strong> basic cellular level up<br />

to <strong>the</strong>ir advanced mutual co-ord<strong>in</strong>ation<br />

level dur<strong>in</strong>g sleep.<br />

Walter & Miller’s Textbook <strong>of</strong><br />

Radio<strong>the</strong>rapy by Paul Symonds, Charles<br />

Deehan, Ca<strong>the</strong>r<strong>in</strong>e Meredith <strong>and</strong> John Mills<br />

(Elsevier Health Sciences) covers underly<strong>in</strong>g<br />

pr<strong>in</strong>ciples <strong>of</strong> physics <strong>and</strong> <strong>of</strong>fers a systematic<br />

review <strong>of</strong> tumour sites, concentrat<strong>in</strong>g on <strong>the</strong><br />

role <strong>of</strong> radio<strong>the</strong>rapy <strong>in</strong> <strong>the</strong> treatment <strong>of</strong><br />

malignant disease <strong>and</strong> sett<strong>in</strong>g its use <strong>in</strong><br />

context with chemo<strong>the</strong>rapy <strong>and</strong> surgery.<br />

Technologies <strong>of</strong> Medical Sciences by<br />

Renato Jorge, Joao Tavares, Marcos Barbosa <strong>and</strong><br />

Alan Slade (Spr<strong>in</strong>ger) explores some <strong>of</strong> <strong>the</strong><br />

latest <strong>in</strong>novations be<strong>in</strong>g employed <strong>in</strong><br />

medic<strong>in</strong>e. It covers areas such as<br />

computation modell<strong>in</strong>g <strong>and</strong> simulation,<br />

image process<strong>in</strong>g <strong>and</strong> analysis, medical<br />

imag<strong>in</strong>g, human motion <strong>and</strong> posture, tissue<br />

eng<strong>in</strong>eer<strong>in</strong>g, design <strong>and</strong> development <strong>of</strong><br />

medical devices <strong>and</strong> mechanic biology.<br />

How to L<strong>and</strong> a Top-pay<strong>in</strong>g Medical<br />

<strong>Physics</strong> Pr<strong>of</strong>essors Job by R<strong>and</strong>y Spencer<br />

(Emereo Ltd) is a complete guide to<br />

opportunities, resumés, cover letters,<br />

<strong>in</strong>terviews, salaries <strong>and</strong> promotions.<br />

Towards Practical Bra<strong>in</strong>–Computer<br />

Interfaces by Brendan Allison, Stephen<br />

Dunne, Robert Leeb, Jose Millan <strong>and</strong> Anton<br />

Nijholt (Spr<strong>in</strong>ger) features contributions by<br />

many <strong>of</strong> <strong>the</strong> top bra<strong>in</strong>–computer <strong>in</strong>terface<br />

researchers <strong>and</strong> developers. This book<br />

reviews <strong>the</strong> latest progress <strong>in</strong> <strong>the</strong><br />

components <strong>of</strong> BCIs with a discussion that<br />

<strong>in</strong>cludes a range <strong>of</strong> practical issues <strong>in</strong> an<br />

emerg<strong>in</strong>g BCI-enabled community.<br />

Po<strong>in</strong>t-<strong>of</strong>-Care Diagnostics on a Chip by<br />

David Issadore <strong>and</strong> Robert Westervelt<br />

(Spr<strong>in</strong>ger) reviews <strong>the</strong> latest biochip<br />

technology, exam<strong>in</strong><strong>in</strong>g progress <strong>in</strong> mov<strong>in</strong>g<br />

medical tests out <strong>of</strong> <strong>the</strong> laboratory <strong>and</strong> <strong>in</strong>to<br />

<strong>the</strong> home, with automated <strong>and</strong> <strong>in</strong>expensive<br />

USMAN I. LULA | SCOPE<br />

technology that provides cl<strong>in</strong>icians with<br />

real-time biochemical data.<br />

External Beam Radio<strong>the</strong>rapy, 2nd Edition<br />

by Peter Hosk<strong>in</strong>s (Oxford University Press)<br />

provides practical guidance <strong>of</strong> <strong>the</strong> use <strong>of</strong><br />

external beam <strong>the</strong>rapy. It takes <strong>the</strong> reader<br />

through <strong>the</strong> basic pr<strong>in</strong>ciples cover<strong>in</strong>g<br />

<strong>in</strong>dication, treatment <strong>and</strong> <strong>the</strong>n develop<strong>in</strong>g<br />

this by <strong>in</strong>dividual sites.<br />

New Reports<br />

n Functionality <strong>and</strong> Operation <strong>of</strong><br />

Fluoroscopic Automatic Brightness<br />

Control/Automatic Dose Rate Control<br />

Logic <strong>in</strong> Modern Cardiovascular <strong>and</strong><br />

Interventional Angiography Systems: A<br />

Report <strong>of</strong> Task Group 125, Imag<strong>in</strong>g<br />

<strong>Physics</strong> Committee. Medical <strong>Physics</strong> 2012;<br />

Volume 39, No. 5.<br />

n Dose Calculations for Photon-emitt<strong>in</strong>g<br />

Brachy<strong>the</strong>rapy Sources with Average<br />

Energy Higher than 50 keV: Report <strong>of</strong> <strong>the</strong><br />

AAPM <strong>and</strong> ESTRO. Medical <strong>Physics</strong> 2012;<br />

Volume 39, No. 5.<br />

n Avoidance <strong>of</strong> Unnecessary Dose to<br />

Patient while Transition<strong>in</strong>g from<br />

Analogue to Digital Radiology. Medical<br />

<strong>Physics</strong> 2012; IAEA TECDOC 1667.<br />

n Guidance on <strong>the</strong> Import <strong>and</strong> Export <strong>of</strong><br />

Radioactive Sources. IAEA; 2012.<br />

n Communications with <strong>the</strong> Public <strong>in</strong> a<br />

Nuclear or Radiological Emergency,<br />

Emergency Preparedness <strong>and</strong> Response,<br />

EPR-Public Communications. IAEA; 2012.<br />

n Risk <strong>of</strong> Solid Cancers follow<strong>in</strong>g Radiation<br />

Exposure: Estimates for <strong>the</strong> UK<br />

Population, RCE 19. HPA; 2012.<br />

n Health Effects from Radi<strong>of</strong>requency<br />

Electromagnetic Fields, RCE 20. HPA;<br />

2012.<br />

n Doses to Patients from Radiographic <strong>and</strong><br />

Fluoroscopic X-ray Imag<strong>in</strong>g Procedures<br />

<strong>in</strong> <strong>the</strong> UK – 2010 Review, HPA-CRCE-034.<br />

HPA; 2012.<br />

n The Measurement <strong>of</strong> X-Ray Beam Size<br />

from Dental Panoramic Radiography<br />

Equipment, HPA-CRCE-032. HPA; 2012.<br />

n Radio<strong>the</strong>rapy Dataset Annual Report<br />

2009/2010. Department <strong>of</strong> Health,<br />

Gateway Reference 16350; 2011.<br />

n Safety Is No Accident – A Framework for<br />

Quality Radiation Oncology <strong>and</strong> Care.<br />

ASTRO Blue Book; 2012.<br />

SCOPE | SEPTEMBER 2012 | 45


A HISTORY OF MEDICAL PHYSICS<br />

THE STORY OF JULES GAVARRET (1809–1890)<br />

FRANCIS DUCK returns to Paris for <strong>the</strong> seventh part <strong>of</strong> his history series<br />

ules Gavarret<br />

(1809–1890) was<br />

Pr<strong>of</strong>essor <strong>of</strong> Medical<br />

<strong>Physics</strong> <strong>in</strong> <strong>the</strong> Faculty <strong>of</strong><br />

Medic<strong>in</strong>e <strong>in</strong> Paris for 33<br />

years. By <strong>the</strong> time <strong>of</strong> his<br />

death he had earned an enviable<br />

national <strong>and</strong> <strong>in</strong>ternational<br />

reputation, <strong>and</strong> many tributes were<br />

paid for his contributions to physics, 1<br />

to medic<strong>in</strong>e2 <strong>and</strong> to education. 3 He<br />

was <strong>the</strong>n largely forgotten. Recently,<br />

his name has reappeared <strong>in</strong> <strong>the</strong><br />

histories <strong>of</strong> medic<strong>in</strong>e <strong>and</strong> science. 4,5<br />

J<br />

This is his story.<br />

46 | SEPTEMBER 2012 | SCOPE<br />

FIGURE 1.<br />

Jules Gavarret<br />

(1809–1890) (BIU<br />

Santé, Paris).<br />

▼<br />

Louis-Dom<strong>in</strong>ique-Jules Gavarret<br />

(figure 1) was <strong>the</strong> second son <strong>of</strong> a<br />

prov<strong>in</strong>cial doctor. He was born on<br />

28th January 1809, <strong>in</strong> <strong>the</strong> small town<br />

<strong>of</strong> Astaffort <strong>in</strong> sou<strong>the</strong>rn France. His<br />

<strong>in</strong>telligence <strong>and</strong> ability was<br />

recognised early <strong>and</strong>, on leav<strong>in</strong>g his<br />

local town college <strong>in</strong> Agen, he<br />

ga<strong>in</strong>ed a place at <strong>the</strong> prestigious<br />

École polytechnique <strong>in</strong> Paris, a<br />

gateway to high <strong>of</strong>fice <strong>in</strong> <strong>the</strong><br />

pr<strong>of</strong>essions, education <strong>and</strong><br />

government. Here he met some <strong>of</strong><br />

<strong>the</strong> greatest men <strong>in</strong> French science<br />

<strong>in</strong>clud<strong>in</strong>g Siméon Poisson<br />

(1781–1840) <strong>and</strong> Claude-Louis<br />

Navier (1785–1836). He <strong>in</strong>itially<br />

turned away from <strong>the</strong> family’s<br />

pr<strong>of</strong>ession, medic<strong>in</strong>e. For a young<br />

man who would be later described<br />

by a friend as a pense-libre, a<br />

freeth<strong>in</strong>ker, 3 his first career choice<br />

was surpris<strong>in</strong>g: he jo<strong>in</strong>ed <strong>the</strong> army.<br />

But his own character <strong>and</strong> army<br />

discipl<strong>in</strong>e were <strong>in</strong>compatible, <strong>and</strong><br />

after 2 years at <strong>the</strong> artillery <strong>of</strong>ficers’<br />

tra<strong>in</strong><strong>in</strong>g school at Metz, he had a<br />

row <strong>and</strong> resigned. Some <strong>of</strong> his<br />

military colleagues never forgave<br />

this <strong>in</strong>sult.


GAVARRET’S CAREER IN<br />

MEDICINE<br />

Back <strong>in</strong> Paris <strong>in</strong> early 1833, now 24years-old<br />

<strong>and</strong> with a strong <strong>in</strong>terest <strong>in</strong><br />

ma<strong>the</strong>matics <strong>and</strong> physics, but also <strong>the</strong><br />

need to ga<strong>in</strong> a pr<strong>of</strong>essional<br />

qualification, Gavarret turned to<br />

medic<strong>in</strong>e. He spent <strong>the</strong> next 10 years<br />

<strong>in</strong> <strong>the</strong> Faculty <strong>of</strong> Medic<strong>in</strong>e, at first <strong>in</strong><br />

medical tra<strong>in</strong><strong>in</strong>g, <strong>and</strong> subsequently <strong>in</strong><br />

physiological research.<br />

It is usually possible to see early<br />

evidence <strong>in</strong> publications <strong>of</strong> a creative<br />

talent that will later flower <strong>in</strong>to a full<br />

scientific career. Not so with<br />

Gavarret. His first publication, <strong>in</strong><br />

1840, was a full-length monograph on<br />

medical statistics. 4,6 At that time, <strong>the</strong><br />

term statistics meant, for <strong>the</strong> medical<br />

pr<strong>of</strong>ession, simply <strong>the</strong> careful<br />

ga<strong>the</strong>r<strong>in</strong>g <strong>and</strong> tabulation <strong>of</strong><br />

comparative data.<br />

Our present underst<strong>and</strong><strong>in</strong>g <strong>of</strong><br />

probabilities, correlations <strong>and</strong><br />

associations was entirely absent, <strong>and</strong><br />

Gavarret’s book was <strong>the</strong> first time<br />

that such analysis had been applied<br />

to medical data. Built around<br />

Poisson’s methods <strong>of</strong> statistical<br />

analysis, Gavarret used many<br />

examples to demonstrate <strong>the</strong><br />

importance <strong>of</strong> us<strong>in</strong>g large numbers <strong>of</strong><br />

observations, <strong>of</strong> ascerta<strong>in</strong><strong>in</strong>g limits <strong>of</strong><br />

error from laws <strong>of</strong> probability, <strong>and</strong><br />

<strong>the</strong> erroneous nature <strong>of</strong> results drawn<br />

without such analysis. It is perhaps<br />

unsurpris<strong>in</strong>g that this sem<strong>in</strong>al work,<br />

by a <strong>the</strong>n unknown author, failed to<br />

make <strong>the</strong> impact it deserved. Medical<br />

reputations were potentially<br />

threatened, be<strong>in</strong>g <strong>of</strong>ten based on<br />

particular treatment regimes. It<br />

would not be until <strong>the</strong> twentieth<br />

century that such statistical methods<br />

started to make any <strong>in</strong>roads <strong>in</strong>to<br />

medical th<strong>in</strong>k<strong>in</strong>g.<br />

Gavarret <strong>the</strong>n engaged <strong>in</strong> an<br />

<strong>in</strong>tensive <strong>and</strong> highly productive 4year<br />

period <strong>of</strong> orig<strong>in</strong>al physiological<br />

research, under <strong>the</strong> renowned<br />

physiologist Gabriel Andral<br />

(1797–1876). He published work on<br />

haematological pathology, 7<br />

emphysema <strong>and</strong> cardiopulmonary<br />

disease (his MD <strong>the</strong>sis), analysis <strong>of</strong><br />

exhaled CO 2 (figure 2) <strong>and</strong> body<br />

temperature dur<strong>in</strong>g <strong>in</strong>termittent<br />

fever. His emerg<strong>in</strong>g talent started to<br />

be appreciated outside France. The<br />

Lancet gave his work positive<br />

reviews, <strong>the</strong> studies on<br />

haematological pathology were<br />

published <strong>in</strong> America, 7 <strong>and</strong> his book<br />

on medical statistics was translated<br />

<strong>in</strong>to German.<br />

THE CONCOURS FOR THE<br />

CHAIR OF MEDICAL PHYSICS<br />

The chair <strong>of</strong> medical physics <strong>in</strong> <strong>the</strong><br />

Faculty <strong>of</strong> Medic<strong>in</strong>e <strong>in</strong> Paris fell<br />

vacant on 20th July 1843, when Pierre<br />

Pelletan resigned. Pelletan had<br />

become heavily <strong>in</strong>volved <strong>in</strong> bus<strong>in</strong>ess<br />

<strong>and</strong> <strong>in</strong>dustrial enterprises <strong>and</strong> had<br />

overstretched himself f<strong>in</strong>ancially.<br />

Pressed by creditors, he resigned<br />

from his post <strong>and</strong> left France. 8<br />

The method by which senior<br />

academic posts were filled <strong>in</strong> France<br />

at this time was known as <strong>the</strong><br />

concours (contest), a gruell<strong>in</strong>g process<br />

<strong>of</strong> competitive <strong>in</strong>terviews <strong>and</strong><br />

exam<strong>in</strong>ations. The 1843 concours for<br />

<strong>the</strong> chair <strong>of</strong> medical physics consisted<br />

<strong>of</strong> four exam<strong>in</strong>ations, one written,<br />

two oral <strong>and</strong> a practical, <strong>and</strong> <strong>the</strong><br />

defence <strong>of</strong> a <strong>the</strong>sis. The c<strong>and</strong>idates<br />

appeared before a formidable<br />

academic panel consist<strong>in</strong>g <strong>of</strong> n<strong>in</strong>e<br />

pr<strong>of</strong>essors from <strong>the</strong> Faculty <strong>of</strong><br />

Medic<strong>in</strong>e <strong>and</strong> four from <strong>the</strong> Faculty<br />

<strong>of</strong> Science. The panel was chaired by<br />

Claude Pouillet (1790–1868), a<br />

physicist whose name appears<br />

repeatedly <strong>in</strong> <strong>the</strong> story <strong>of</strong> medical<br />

physics. 8,9<br />

The field was very strong. Of <strong>the</strong><br />

six c<strong>and</strong>idates, three had taken part<br />

<strong>in</strong> <strong>the</strong> previous concours, 13 years<br />

earlier. 8 Jacques-Henri Maissiat<br />

(1805–1878) had been Pelletan’s<br />

assistant (agrégé) <strong>and</strong> had been giv<strong>in</strong>g<br />

<strong>the</strong> medical physics course s<strong>in</strong>ce<br />

1839. The prize was highly attractive.<br />

The post was tenured. The salary was<br />

6,000 francs, about 10 times <strong>the</strong><br />

average wage <strong>of</strong> a work<strong>in</strong>g man at<br />

that time, <strong>and</strong> well towards <strong>the</strong> upper<br />

end <strong>of</strong> government-supported<br />

salaries. Fur<strong>the</strong>rmore, <strong>the</strong>re was no<br />

comparable post elsewhere at this<br />

time: <strong>in</strong> <strong>the</strong> o<strong>the</strong>r two full medical<br />

schools <strong>in</strong> France, at Montpellier <strong>and</strong><br />

Strasbourg, <strong>the</strong> teach<strong>in</strong>g <strong>of</strong> medical<br />

physics was still comb<strong>in</strong>ed with that<br />

<strong>of</strong> hygiene.<br />

The written exam<strong>in</strong>ation was<br />

about <strong>the</strong> human voice. For <strong>the</strong> first<br />

oral exam<strong>in</strong>ation <strong>the</strong> c<strong>and</strong>idates were<br />

each given <strong>the</strong>ir own topic, with 24<br />

hours’ notice to prepare a lecture. The<br />

six topics were: atmospheric<br />

humidity <strong>and</strong> its physiological<br />

effects; electrical phenomena <strong>in</strong> fish<br />

(Gavarret’s subject); sight; animal<br />

heat; capillarity <strong>and</strong> endosmosis, <strong>and</strong><br />

radiant heat. There were only three<br />

topics for <strong>the</strong> second oral, which <strong>the</strong><br />

c<strong>and</strong>idates had to prepare with only<br />

3 hours’ notice: <strong>the</strong> microscope <strong>in</strong><br />

medical science; physiology <strong>of</strong> gas<br />

“ Gavarret’s<br />

book was<br />

<strong>the</strong> first<br />

time that<br />

such<br />

analysis<br />

had been<br />

applied to<br />

medical<br />

data<br />

”<br />

HISTORICAL FEATURE | SCOPE<br />

<strong>and</strong> liquid pressure, <strong>and</strong> atmospheric<br />

electricity. The 25-m<strong>in</strong>ute physics<br />

practical exam<strong>in</strong>ation followed: <strong>the</strong><br />

explanation <strong>and</strong> use <strong>of</strong> Rumford’s<br />

calorimeter <strong>and</strong> Cagniard de Latour’s<br />

siren (figure 3). F<strong>in</strong>ally, Gavarret<br />

defended his <strong>the</strong>sis on <strong>the</strong> laws <strong>of</strong><br />

dynamic electricity.<br />

A report <strong>in</strong> <strong>the</strong> press (<strong>the</strong> concours<br />

was public) said that all c<strong>and</strong>idates<br />

performed to a very high st<strong>and</strong>ard.<br />

Gavarret himself was deemed to have<br />

<strong>the</strong> best m<strong>in</strong>d. The votes <strong>of</strong> <strong>the</strong> panel<br />

were equally divided between<br />

Gavarret <strong>and</strong> Maissiat, six each,<br />

leav<strong>in</strong>g Pouillet to make <strong>the</strong> cast<strong>in</strong>g<br />

vote. Maissiat represented <strong>the</strong> safe<br />

option, known by <strong>the</strong> medical faculty,<br />

<strong>and</strong> capable <strong>of</strong> competent delivery <strong>of</strong><br />

<strong>the</strong> first-year physics lectures to a high<br />

st<strong>and</strong>ard. Gavarret had presented as<br />

an outst<strong>and</strong><strong>in</strong>g <strong>and</strong> clear-m<strong>in</strong>ded<br />

<strong>in</strong>tellect, with a high-quality, though<br />

brief, track record <strong>in</strong> research, but<br />

with no teach<strong>in</strong>g experience.<br />

But Pouillet knew that he was<br />

liv<strong>in</strong>g <strong>in</strong> a time <strong>of</strong> extraord<strong>in</strong>ary<br />

change, both <strong>in</strong> physics <strong>and</strong> <strong>in</strong><br />

medic<strong>in</strong>e, <strong>and</strong> this was a critical<br />

appo<strong>in</strong>tment if Paris had any chance<br />

<strong>of</strong> ma<strong>in</strong>ta<strong>in</strong><strong>in</strong>g its <strong>in</strong>ternational<br />

position as a centre <strong>of</strong> medical<br />

excellence. He chose Jules Gavarret.<br />

The endorsement <strong>of</strong> his appo<strong>in</strong>tment<br />

was announced as a m<strong>in</strong>isterial order<br />

on 16th January 1844.<br />

GAVARRET AS A TEACHER<br />

The record <strong>of</strong> Gavarret’s life for <strong>the</strong><br />

next 10 years is muted. He settled<br />

himself <strong>in</strong>to his new role, his ideas on<br />

how to apply physics to medic<strong>in</strong>e<br />

undergo<strong>in</strong>g a slow gestation. He<br />

engaged quickly with <strong>the</strong> life <strong>of</strong> <strong>the</strong><br />

faculty, <strong>and</strong> <strong>in</strong> <strong>the</strong> year <strong>of</strong> his<br />

appo<strong>in</strong>tment as pr<strong>of</strong>essor he also<br />

became assessor to <strong>the</strong> Dean. But<br />

those who might have expected<br />

fur<strong>the</strong>r research output were<br />

disappo<strong>in</strong>ted, <strong>and</strong> no new textbook on<br />

medical physics appeared to replace<br />

Pelletan’s Physique general et médicale.<br />

His defence might have been that, <strong>in</strong><br />

common with all academics, <strong>the</strong><br />

comb<strong>in</strong>ation <strong>of</strong> lecture preparation,<br />

exam<strong>in</strong>ations, tutorials <strong>and</strong><br />

adm<strong>in</strong>istration left no time for<br />

anyth<strong>in</strong>g else; <strong>and</strong> fur<strong>the</strong>rmore,<br />

medical tra<strong>in</strong><strong>in</strong>g at that time required<br />

no laboratory experience, so he had no<br />

space for experimental work. Perhaps<br />

Pouillet’s confidence had been<br />

misplaced, <strong>and</strong> he had selected<br />

ano<strong>the</strong>r time-serv<strong>in</strong>g middle-rate<br />

academic.<br />

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48 | SEPTEMBER 2012 | SCOPE


But Gavarret had not ceased<br />

th<strong>in</strong>k<strong>in</strong>g. In 1849 we see <strong>the</strong> next<br />

example <strong>in</strong> which he demonstrated<br />

that he was follow<strong>in</strong>g developments at<br />

<strong>the</strong> <strong>in</strong>terface between physics <strong>and</strong><br />

medic<strong>in</strong>e, <strong>in</strong> this case electricity.<br />

Conventional wisdom <strong>in</strong> France still<br />

broadly held to Volta’s electrochemical<br />

model to expla<strong>in</strong> all galvanic sources,<br />

reject<strong>in</strong>g Galvani’s view <strong>of</strong> animal<br />

electricity as an <strong>in</strong>nate property <strong>of</strong><br />

liv<strong>in</strong>g tissues. Gavarret published a<br />

careful review based on <strong>the</strong> best<br />

evidence he could f<strong>in</strong>d, conclud<strong>in</strong>g<br />

that much criticism <strong>of</strong> Galvani had<br />

been <strong>in</strong>appropriate, <strong>and</strong> that <strong>the</strong>re was<br />

much new evidence to suggest that<br />

electric phenomena were <strong>in</strong>herent to<br />

all liv<strong>in</strong>g matter.<br />

HEAT AND ELECTRICITY<br />

Gavarret planned to write a book<br />

about animal electricity. He said so <strong>in</strong><br />

<strong>the</strong> <strong>in</strong>troduction to his next book, on<br />

animal heat. 10 This book was a<br />

thorough review <strong>of</strong> a topic for which<br />

considerable advances <strong>in</strong> measurement<br />

techniques (figure 4) <strong>and</strong><br />

underst<strong>and</strong><strong>in</strong>g had recently occurred.<br />

This was to be <strong>the</strong> first <strong>in</strong> his Medical<br />

<strong>Physics</strong> series, <strong>in</strong> which he <strong>in</strong>tended to<br />

review carefully each aspect <strong>of</strong> physics<br />

<strong>in</strong> its relationship to medic<strong>in</strong>e. (In fact,<br />

none <strong>of</strong> his later books bore this series<br />

title.) Animal electricity would have<br />

been Volume 2 <strong>in</strong> this series. But<br />

controversy still surrounded this<br />

subject: Du Bois Reymond’s visit to<br />

Paris <strong>in</strong> 1850 did little to clear <strong>the</strong> air. 9<br />

So, <strong>in</strong>stead, Gavarret’s next book was a<br />

thorough review on <strong>the</strong> current state <strong>of</strong><br />

electricity as a whole, publish<strong>in</strong>g his<br />

Traité d’Électricitié <strong>in</strong> two volumes <strong>in</strong><br />

1858 <strong>and</strong> 1859. However, he omitted<br />

biomedical electricity, which he says<br />

needed to mature fur<strong>the</strong>r before a<br />

proper review could be written. This<br />

book established his reputation as an<br />

academic author who could expla<strong>in</strong><br />

difficult concepts <strong>in</strong> easily-understood<br />

prose, without compromis<strong>in</strong>g scientific<br />

accuracy. The book was also soon<br />

published <strong>in</strong> German.<br />

He was immediately <strong>in</strong>vited to<br />

serve as a member <strong>of</strong> a commission <strong>of</strong><br />

<strong>the</strong> M<strong>in</strong>istry <strong>of</strong> F<strong>in</strong>ance to give advice<br />

on <strong>the</strong> electric telegraph. This was at<br />

<strong>the</strong> start <strong>of</strong> <strong>the</strong> n<strong>in</strong>eteenth-century<br />

communications revolution, both <strong>in</strong><br />

extent <strong>and</strong> speed, with an impact<br />

comparable with that which arose from<br />

<strong>the</strong> <strong>in</strong>troduction <strong>of</strong> <strong>the</strong> World Wide<br />

Web. Up to 1844, when <strong>the</strong> first electric<br />

telegraph l<strong>in</strong>e was <strong>in</strong>stalled from Paris<br />

to Tours, <strong>the</strong>re were only five<br />

semaphore l<strong>in</strong>es <strong>in</strong> France, <strong>and</strong> a<br />

message took 20 m<strong>in</strong>utes to reach<br />

Toulon. With<strong>in</strong> 7 years, London <strong>and</strong><br />

Paris were <strong>in</strong> <strong>in</strong>stantaneous<br />

communication by a telegraph cable<br />

under <strong>the</strong> English Channel, <strong>and</strong> by<br />

1860 <strong>the</strong>re were 22,000 km <strong>of</strong> l<strong>in</strong>es<br />

criss-cross<strong>in</strong>g <strong>the</strong> whole <strong>of</strong> France. In<br />

1861 Gavarret published a detailed<br />

book on <strong>the</strong> telegraph (figure 5). 11 This<br />

book was aga<strong>in</strong> followed by a German<br />

translation.<br />

LIGHT AND SOUND<br />

Gavarret’s next books, on optics <strong>and</strong><br />

acoustics, endorsed his reputation as<br />

an outst<strong>and</strong><strong>in</strong>g educational<br />

communicator. They also serve to<br />

emphasise his underst<strong>and</strong><strong>in</strong>g <strong>of</strong> his<br />

unique role – to underst<strong>and</strong><br />

contemporary developments <strong>in</strong><br />

physics <strong>in</strong> depth, <strong>and</strong> to <strong>in</strong>terpret<br />

<strong>the</strong>m for his colleagues <strong>in</strong> medic<strong>in</strong>e.<br />

Much had already been written on <strong>the</strong><br />

optics <strong>of</strong> <strong>the</strong> eye, <strong>and</strong> he saw it as<br />

unnecessary to go over this well-tilled<br />

soil. So, <strong>in</strong>stead, he wrote an<br />

<strong>in</strong>terpretation <strong>of</strong> Gauss’s 1840<br />

Dioptrishe Untersuchungen. In his book,<br />

entitled Images par reflexion et par<br />

refraction (1866), he gave a clear<br />

exposition <strong>of</strong> Gauss’s paraxial<br />

approximation for focal systems,<br />

giv<strong>in</strong>g a tool us<strong>in</strong>g pr<strong>in</strong>cipal <strong>and</strong><br />

nodal po<strong>in</strong>ts that could be easily<br />

applied <strong>in</strong> physiological optics. The<br />

preface <strong>of</strong> <strong>the</strong> 1891 translated Russian<br />

edition <strong>of</strong> Gavarret’s book emphasises<br />

its considerable value <strong>in</strong> <strong>the</strong> teach<strong>in</strong>g<br />

<strong>of</strong> optics.<br />

In his last book 12 he reviewed <strong>the</strong><br />

mechanisms <strong>of</strong> speech <strong>and</strong> hear<strong>in</strong>g,<br />

draw<strong>in</strong>g on <strong>the</strong> work <strong>of</strong> Helmholtz<br />

<strong>and</strong> Fourier, <strong>in</strong>clud<strong>in</strong>g several<br />

appendices <strong>of</strong> a more ma<strong>the</strong>matical<br />

nature. The text itself draws strongly<br />

on experimental physics, <strong>in</strong>clud<strong>in</strong>g<br />

many examples <strong>of</strong> physical<br />

measurements applied to<br />

physiological acoustics (figure 6).<br />

BIOLOGICAL PHYSICS<br />

Gavarret was always concerned to<br />

avoid a too narrow <strong>in</strong>terpretation <strong>of</strong><br />

<strong>the</strong> physics syllabus for first-year<br />

medical students. He knew that <strong>the</strong>re<br />

was <strong>in</strong>sufficient time dur<strong>in</strong>g his three<br />

physics lectures per week to do justice<br />

to <strong>the</strong> broader applications <strong>of</strong> physics<br />

to medic<strong>in</strong>e. In response to this<br />

conflict, around 1866 he started to<br />

<strong>of</strong>fer an advanced course called<br />

Biological <strong>Physics</strong>, where he assumed<br />

his audience had some knowledge not<br />

only <strong>of</strong> physics, but also <strong>of</strong><br />

FIGURE 2.<br />

[TOP LEFT]<br />

Gavarret’s<br />

apparatus for <strong>the</strong><br />

measurement <strong>of</strong><br />

expired CO2 . 10<br />

▼<br />

FIGURE 3.<br />

[TOP RIGHT]<br />

Cagniard de<br />

Latour’s siren.<br />

▼<br />

FIGURE 4.<br />

[MIDDLE LEFT]<br />

Intra-muscular<br />

temperature<br />

us<strong>in</strong>g<br />

<strong>the</strong>rmocouples by<br />

A.-C. Becquerel<br />

(1788–1878):<br />

1835. 10<br />

▼<br />

FIGURE 5.<br />

[BOTTOM RIGHT]<br />

Electrical<br />

telegraph<br />

transmitter c.<br />

1850. 11<br />

▼<br />

FIGURE 6.<br />

[BOTTOM LEFT]<br />

Voice analysis<br />

us<strong>in</strong>g <strong>the</strong> danc<strong>in</strong>g<br />

flame. 12<br />

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HISTORICAL FEATURE | SCOPE<br />

physiology, pathology <strong>and</strong> anatomy.<br />

Such was <strong>the</strong> <strong>in</strong>terest <strong>in</strong> <strong>the</strong>se lectures<br />

that typically more than half his<br />

audience consisted <strong>of</strong> qualified<br />

doctors, anxious to update <strong>the</strong>mselves<br />

on <strong>the</strong> possible impact on <strong>the</strong>ir<br />

medical practice <strong>of</strong> new developments<br />

<strong>in</strong> physics.<br />

In 1869, he published a book<br />

derived from this course, Phénomènes<br />

physique de la vie. Once more we see<br />

him apply<strong>in</strong>g modern physics<br />

concepts to medical problems,<br />

allow<strong>in</strong>g him to peer <strong>in</strong>to <strong>the</strong> future<br />

whilst rema<strong>in</strong><strong>in</strong>g cautious about<br />

<strong>in</strong>appropriate extrapolation from<br />

present knowledge. In <strong>the</strong><br />

<strong>in</strong>troduction he applauds <strong>the</strong> value <strong>of</strong><br />

physical measurement, us<strong>in</strong>g <strong>the</strong><br />

example <strong>of</strong> Marey’s multichannel<br />

measurements on <strong>in</strong>tra-cardiac<br />

pressure: he was Marey’s exam<strong>in</strong>er for<br />

his <strong>the</strong>sis <strong>in</strong> 1859.<br />

Étienne-Jules Marey (1830–1904)<br />

later became famous for his use <strong>of</strong><br />

photographic methods for analysis <strong>of</strong><br />

animal locomotion. He even <strong>in</strong>cluded<br />

<strong>the</strong> comment that, s<strong>in</strong>ce <strong>the</strong> bra<strong>in</strong> is<br />

do<strong>in</strong>g work dur<strong>in</strong>g th<strong>in</strong>k<strong>in</strong>g,<br />

compar<strong>in</strong>g, want<strong>in</strong>g <strong>and</strong> so on, its<br />

energy use may be sufficient cause<br />

<strong>and</strong> not just a necessary condition for<br />

all mental activity, <strong>and</strong> by implication<br />

subject to <strong>the</strong> same energy<br />

considerations as any o<strong>the</strong>r organ. In<br />

this he draws on <strong>the</strong> new concepts <strong>in</strong><br />

physics that clearly excited him most,<br />

<strong>the</strong> reciprocity <strong>of</strong> forces <strong>and</strong> <strong>the</strong><br />

conservation <strong>of</strong> energy. Us<strong>in</strong>g <strong>the</strong><br />

term<strong>in</strong>ology <strong>of</strong> <strong>the</strong> time, he says that<br />

travaille is as universal as mass, <strong>and</strong><br />

that its conservation is as<br />

fundamentally true <strong>in</strong> liv<strong>in</strong>g as <strong>in</strong><br />

<strong>in</strong>organic materials. It is here, he says,<br />

that physiological phenomena, heat,<br />

bio-electricity, muscular power <strong>and</strong><br />

nutrition, will f<strong>in</strong>d <strong>the</strong>ir true<br />

explanation. In comparison with his<br />

British contemporaries, he felt no need<br />

to mention any apparent conflict with<br />

religious thought, although he had to<br />

fight aga<strong>in</strong>st a residual belief <strong>in</strong> a vital<br />

life force, still ma<strong>in</strong>ta<strong>in</strong>ed by <strong>the</strong><br />

dom<strong>in</strong>ant French physiologist Claude<br />

Bernard (1813–1878).<br />

It was left to his younger colleagues<br />

Desplats <strong>and</strong> Gariel to write <strong>the</strong> next<br />

full medical physics text 13 <strong>in</strong> 1870, to<br />

which Gavarret added an<br />

<strong>in</strong>troduction.<br />

POLITICS<br />

Jules Gavarret lived through a highly<br />

turbulent time <strong>in</strong> French history. He<br />

was just 4 years old when Napoleon<br />

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lost <strong>the</strong> battle <strong>of</strong> Waterloo. Dur<strong>in</strong>g his<br />

formative teenage years, <strong>the</strong> country<br />

was under <strong>the</strong> strict right-w<strong>in</strong>g<br />

regime <strong>of</strong> Charles X. The year after<br />

his arrival as a student <strong>in</strong> Paris, he<br />

watched <strong>the</strong> violent riots that<br />

deposed Charles <strong>and</strong> established <strong>the</strong><br />

July Monarchy <strong>of</strong> Louis Phillipe.<br />

Gavarret lived through <strong>the</strong> 1848<br />

revolution <strong>and</strong> <strong>the</strong> coup d’état <strong>of</strong> 1852,<br />

which created <strong>the</strong> second Empire<br />

under Napoleon III. He survived <strong>the</strong><br />

siege <strong>of</strong> Paris, <strong>the</strong> subsequent<br />

commune, <strong>and</strong> observed its bloody<br />

suppression <strong>and</strong> <strong>the</strong> formation <strong>of</strong> <strong>the</strong><br />

Republic. At each sw<strong>in</strong>g <strong>of</strong> <strong>the</strong><br />

political pendulum, academic<br />

positions, be<strong>in</strong>g public appo<strong>in</strong>tments,<br />

were potentially under threat.<br />

Pouillet, for example, lost his<br />

pr<strong>of</strong>essorship at <strong>the</strong> Conservatoire des<br />

arts et métiers <strong>in</strong> 1852 when he refused<br />

to swear allegiance to <strong>the</strong> Emperor.<br />

Gavarret’s name is nowhere l<strong>in</strong>ked to<br />

political activity <strong>and</strong> he was able to<br />

ga<strong>in</strong> <strong>the</strong> approval <strong>of</strong> each new<br />

adm<strong>in</strong>istration.<br />

Decorated with <strong>the</strong> Legion<br />

d’honneur <strong>in</strong> 1847, towards <strong>the</strong> end <strong>of</strong><br />

<strong>the</strong> July Monarchy, he was made an<br />

Officer <strong>of</strong> this order <strong>in</strong> 1862 dur<strong>in</strong>g<br />

<strong>the</strong> second Empire, <strong>and</strong> f<strong>in</strong>ally raised<br />

to Comm<strong>and</strong>er <strong>in</strong> 1882 by <strong>the</strong><br />

Republic. Liberal by <strong>in</strong>cl<strong>in</strong>ation, <strong>the</strong><br />

only reference l<strong>in</strong>k<strong>in</strong>g his name to a<br />

political event occurred at <strong>the</strong> start <strong>of</strong><br />

<strong>the</strong> 1867 academic year. Some<br />

students, object<strong>in</strong>g nom<strong>in</strong>ally to<br />

changes <strong>in</strong> <strong>the</strong> open<strong>in</strong>g ceremony,<br />

started s<strong>in</strong>g<strong>in</strong>g <strong>the</strong> Marseillaise as he<br />

entered <strong>the</strong> lecture hall. The row<br />

cont<strong>in</strong>ued <strong>and</strong>, after an hour,<br />

Gavarret reportedly looked at his<br />

REFERENCES<br />

50 | SEPTEMBER 2012 | SCOPE<br />

watch <strong>and</strong> left. It seems that this<br />

demonstration was directed towards<br />

<strong>the</strong> establishment ra<strong>the</strong>r than<br />

aga<strong>in</strong>st him.<br />

GAVARRET’S LATER LIFE<br />

Dur<strong>in</strong>g his early life Gavarret<br />

rema<strong>in</strong>ed s<strong>in</strong>gle. Eventually, on 14th<br />

September 1860, he married Eudoxie<br />

B<strong>in</strong>esse de Sa<strong>in</strong>t-Victor, a lady <strong>in</strong> her<br />

late 30s from an aristocratic family.<br />

They set up home <strong>in</strong> rue de Grenelle on<br />

<strong>the</strong> Left Bank, <strong>and</strong> became part <strong>of</strong><br />

Parisian society. Affable <strong>and</strong> replete<br />

with anecdotes, told with manners <strong>of</strong><br />

speech from his sou<strong>the</strong>rn childhood,<br />

Gavarret presided over many<br />

Saturday night soirees with ‘<strong>the</strong> ladies<br />

<strong>of</strong> medical assistants who were<br />

seek<strong>in</strong>g pr<strong>of</strong>essorships’. 5<br />

In 1873 he was appo<strong>in</strong>ted to review<br />

<strong>the</strong> preparatory medical schools, with<br />

a view to recommend<strong>in</strong>g those<br />

appropriate for upgrad<strong>in</strong>g, <strong>and</strong> 6<br />

years later became <strong>the</strong> <strong>in</strong>spectorgeneral<br />

for higher medical education.<br />

He cont<strong>in</strong>ued writ<strong>in</strong>g, contribut<strong>in</strong>g<br />

articles on popular science to <strong>the</strong><br />

Moniteur universel <strong>and</strong> compil<strong>in</strong>g all<br />

17 physics def<strong>in</strong>itions <strong>in</strong> <strong>the</strong><br />

Dictionnaire encyclopédique des sciences<br />

médicales. Still active <strong>in</strong> his 70s, he<br />

became President <strong>of</strong> <strong>the</strong> Academy <strong>of</strong><br />

Medic<strong>in</strong>e <strong>in</strong> 1882, <strong>and</strong> presided over<br />

<strong>the</strong> revision <strong>of</strong> <strong>the</strong> French<br />

pharmacopoeia <strong>in</strong> 1884. He retired <strong>in</strong><br />

1885 <strong>and</strong> was subsequently awarded<br />

an honorary pr<strong>of</strong>essorship. He was<br />

replaced by Charles-Marie Gariel<br />

(1841–1924). 1,13 His death came on 30th<br />

August 1890, whilst on holiday with a<br />

friend, <strong>and</strong> only 5 months after that <strong>of</strong><br />

his wife.<br />

1 Gariel C-M. Médec<strong>in</strong>e. In École polytechnique. Livre du<br />

centenaire 1794–1894, 1897; Vol. 3: 394–408.<br />

2 Corlieu A. Centenaire de la Faculté de médec<strong>in</strong>e de Paris<br />

(1794–1894). Ch IV: Chaire de Physique. 1896.<br />

3 Laborde M. Le pr<strong>of</strong>esseur Gavarret. Bull Soc<br />

d’Anthropologie de Paris, 4th ser, 1890; 1: 645–51.<br />

4 Huth E. Jules Gavarret’s Pr<strong>in</strong>cipes Généraux de Statistique<br />

Médicale. J R Soc Med 2008; 101: 205–12.<br />

5 Beyneix A. Le pr<strong>of</strong>esseur Jules Gavarret (1809–1890) et<br />

l’application des méthodes mathématiques et physiques à<br />

la médec<strong>in</strong>e. Bull Acad Natle Med 2001; 185: 1327–35.<br />

6 Gavarret J. Pr<strong>in</strong>cipes généraux de statistique médicale.<br />

Paris, 1840.<br />

7 Andral G. An Essay on <strong>the</strong> Blood <strong>in</strong> Disease. Translated by<br />

Meigs & Stillé. Philadelphia, 1844.<br />

His<br />

high<br />

academic<br />

status<br />

ensured a<br />

legacy for<br />

medical<br />

physics<br />

“<br />

”<br />

GAVARRET’S CONTRIBUTION<br />

TO MEDICAL PHYSICS<br />

The n<strong>in</strong>eteenth century saw<br />

extraord<strong>in</strong>ary advances <strong>in</strong> science,<br />

technology <strong>and</strong> medic<strong>in</strong>e. By his<br />

appo<strong>in</strong>tment as <strong>the</strong> only full pr<strong>of</strong>essor<br />

<strong>of</strong> medical physics <strong>in</strong> France at that<br />

time, Gavarret was placed <strong>in</strong> a unique<br />

position to develop <strong>and</strong> clarify this<br />

new discipl<strong>in</strong>e. It is difficult to fault<br />

him. He ga<strong>in</strong>ed considerable respect<br />

from his medical colleagues as an<br />

outst<strong>and</strong><strong>in</strong>g communicator <strong>and</strong> for<br />

his ability to expla<strong>in</strong> difficult concepts<br />

<strong>of</strong> physics without compromis<strong>in</strong>g<br />

scientific <strong>in</strong>tegrity. He understood<br />

that a medical physicist must<br />

constantly keep abreast <strong>of</strong><br />

developments <strong>in</strong> physics <strong>and</strong><br />

ma<strong>the</strong>matics, which for him <strong>in</strong>cluded<br />

Poisson’s statistics, <strong>the</strong> optics <strong>of</strong><br />

Gauss, <strong>and</strong> <strong>in</strong>sights <strong>in</strong>to acoustics <strong>and</strong><br />

energy conservation from Helmholtz,<br />

<strong>and</strong> be prepared to underst<strong>and</strong> <strong>the</strong>se<br />

<strong>in</strong> depth <strong>in</strong> order to apply <strong>the</strong>m <strong>and</strong><br />

expla<strong>in</strong> <strong>the</strong>m to his medical<br />

colleagues. His high academic status<br />

ensured a legacy for medical physics<br />

both <strong>in</strong> his own highly-respected<br />

department <strong>and</strong> elsewhere <strong>in</strong><br />

France. 14,15,16 With<strong>in</strong> a decade <strong>of</strong> his<br />

death, <strong>the</strong> discovery <strong>of</strong> x-rays <strong>and</strong><br />

radioactivity permanently cemented<br />

<strong>the</strong> relationship between medic<strong>in</strong>e<br />

<strong>and</strong> physics <strong>in</strong> a way that would<br />

probably not have surprised him.<br />

ABOUT THE AUTHOR<br />

Francis Duck is Honorary Consultant<br />

Medical Physicist <strong>in</strong> <strong>the</strong> Department <strong>of</strong><br />

Medical <strong>Physics</strong> <strong>and</strong> Bioeng<strong>in</strong>eer<strong>in</strong>g at<br />

<strong>the</strong> Royal United Hospital Bath NHS<br />

Trust <strong>and</strong> visit<strong>in</strong>g pr<strong>of</strong>essor at <strong>the</strong><br />

University <strong>of</strong> Bath.<br />

Email: f.duck@bath.ac.uk<br />

8 www.scopeonl<strong>in</strong>e.co.uk/pages/articles/history/history.shtml<br />

9 Duck F. A history <strong>of</strong> medical physics – Adolf Fick <strong>and</strong><br />

physiological physics. Scope June 2012: 50–54.<br />

10 Gavarret J. Physique Médicale – de la Chaleur Produite par<br />

les Êtres Vivants. Paris, 1855.<br />

11 Gavarret J. Télégraphie Électrique. Paris, 1861.<br />

12 Gavarret J. Acoustique Biologique – Phénomènes<br />

Physiques de la Phonation et de l’Audition. Paris, 1877.<br />

13 Desplats V, Gariel C-M. Nouveaux Éléments de Physique<br />

Médicale. Paris, 1870.<br />

14 Gréhant N. Manuel de Physique Médicale. Paris, 1869.<br />

15 Wundt W, Monoyer F. Traité Élémentaire de Physique<br />

Médicale. Paris, 1871.<br />

16 Lefèvre J. Manuel de Physique Médicale. Paris, 1889.


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