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Experience the Elekta Differ - Institute of Physics and Engineering in ...

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2011 AAPM–IPEM MEDICAL PHYSICS<br />

TRAVEL GRANT REPORT<br />

JUN DENG Yale New Haven Hospital, New Haven, CT, USA<br />

I<br />

n April 2012 I visited <strong>the</strong> UK<br />

after receiv<strong>in</strong>g an<br />

AAPM–IPEM Medical<br />

<strong>Physics</strong> Travel Grant. Here I<br />

outl<strong>in</strong>e my experiences at<br />

each <strong>of</strong> <strong>the</strong> centres that I went<br />

to <strong>and</strong> <strong>the</strong> people that I met.<br />

16TH APRIL: CASTLE<br />

HILL HOSPITAL<br />

After a long tra<strong>in</strong> ride from London to<br />

Hull, I f<strong>in</strong>ally arrived at <strong>the</strong> Castle<br />

Hill Hospital where Dr Andy Beavis,<br />

Head <strong>of</strong> <strong>the</strong> Radiation <strong>Physics</strong><br />

Department, was <strong>the</strong> host for my first<br />

stop dur<strong>in</strong>g this trip to <strong>the</strong> UK. My<br />

visit started with a tour <strong>of</strong> <strong>the</strong><br />

department led by Dr Beavis. The<br />

whole oncology centre is very new<br />

with eco- <strong>and</strong> patient-friendly designs<br />

everywhere, which to me makes it<br />

seem ra<strong>the</strong>r more like a hotel than a<br />

cancer centre for radio<strong>the</strong>rapy. Then I<br />

gave a lecture talk<strong>in</strong>g about <strong>the</strong><br />

kVCBCT imag<strong>in</strong>g doses <strong>and</strong> <strong>the</strong><br />

associated cancer risks, after which<br />

we had a round-table meet<strong>in</strong>g for<br />

physics staff so that everyone could<br />

get <strong>in</strong>volved <strong>in</strong> a more <strong>in</strong>teractive<br />

discussion. The primary concerns<br />

were about <strong>the</strong> imag<strong>in</strong>g doses <strong>and</strong><br />

why CT manufacturers did a better<br />

job than <strong>the</strong> l<strong>in</strong>ac manufacturers for<br />

CBCT <strong>in</strong> terms <strong>of</strong> imag<strong>in</strong>g dose<br />

reduction, protocol optimisation <strong>and</strong><br />

patient safety. I also learnt that a<br />

virtual CT reconstructor has been<br />

developed by this group so that<br />

virtual CT scans can be simulated to<br />

study <strong>the</strong> correlation between <strong>the</strong><br />

imag<strong>in</strong>g doses <strong>and</strong> <strong>the</strong> image quality<br />

without actually perform<strong>in</strong>g a scan<br />

on a patient. I was very <strong>in</strong>terested <strong>in</strong><br />

this project <strong>and</strong> <strong>in</strong>dicated that our<br />

group was develop<strong>in</strong>g a similar tool<br />

dedicated to CBCT virtual simulation<br />

<strong>and</strong> reconstruction. F<strong>in</strong>ally, I was<br />

lucky enough to experience a state-<strong>of</strong><strong>the</strong>-art<br />

technology named VERT<br />

developed <strong>and</strong> co-founded by Dr<br />

Beavis. VERT (virtual environment<br />

for radio<strong>the</strong>rapy <strong>and</strong> tra<strong>in</strong><strong>in</strong>g) is a<br />

l<strong>in</strong>ac simulator set <strong>in</strong> a 3D virtual<br />

environment, which can help users<br />

tra<strong>in</strong> with full access to <strong>the</strong> l<strong>in</strong>ac<br />

functionality without <strong>in</strong>terfer<strong>in</strong>g with<br />

<strong>the</strong> cl<strong>in</strong>ical workflow. We actually<br />

took a picture as shown <strong>in</strong> figure 1<br />

with VERT displayed <strong>in</strong> <strong>the</strong><br />

background.<br />

FIGURE 1.<br />

Dr Andy Beavis<br />

<strong>and</strong> Jun at<br />

Castle Hill<br />

Hospital.<br />

▼<br />

TRAVEL AWARD | SCOPE<br />

17TH APRIL: CLATTERBRIDGE<br />

CENTRE FOR ONCOLOGY<br />

The follow<strong>in</strong>g day I visited <strong>the</strong><br />

Clatterbridge Centre for Oncology<br />

where Dr Alan Nahum was my<br />

host. We actually started our<br />

conversion with our fond memories<br />

<strong>of</strong> <strong>the</strong> past. I was fasc<strong>in</strong>ated by all<br />

sorts <strong>of</strong> legendary stories told by<br />

Alan about our common friends.<br />

Alan’s postdoc Dr Julien Uzan gave<br />

me a brief <strong>in</strong>troduction to <strong>the</strong>ir latest<br />

research tool called Biosuite, aim<strong>in</strong>g<br />

to facilitate biologically based<br />

treatment plann<strong>in</strong>g <strong>and</strong><br />

optimisation. The s<strong>of</strong>tware analysed<br />

<strong>the</strong> DVH data exported from<br />

conventional treatment plann<strong>in</strong>g<br />

systems <strong>and</strong> computed TCP <strong>and</strong><br />

NTCP based on published Marsden<br />

<strong>and</strong> LKB models. In addition, <strong>the</strong><br />

s<strong>of</strong>tware was able to optimise <strong>the</strong><br />

plan with a fixed NTCP value, <strong>the</strong><br />

so-called isotoxic plann<strong>in</strong>g scheme,<br />

<strong>and</strong> generate a series <strong>of</strong> plans with<br />

different TCP values correspond<strong>in</strong>g<br />

to different fractionations. Later on,<br />

I gave a lecture on kVCBCT <strong>and</strong> was<br />

engaged <strong>in</strong> a very <strong>in</strong>teractive<br />

discussion with dozens <strong>of</strong> physicists<br />

<strong>and</strong> research staff. I enjoyed some<br />

tough questions raised by Alan <strong>and</strong><br />

Dr Ge<strong>of</strong>f Lawrence. F<strong>in</strong>ally, I was<br />

k<strong>in</strong>dly given a tour <strong>of</strong> <strong>the</strong> only<br />

proton radio<strong>the</strong>rapy facility <strong>in</strong> <strong>the</strong><br />

UK, Douglas Cyclotron (figure 2), by<br />

Dr Andrzej Kacperek. It produced a<br />

s<strong>in</strong>gle energy <strong>of</strong> 62 MeV proton<br />

beams dedicated to radio<strong>the</strong>rapy <strong>of</strong><br />

eye tumours due to its limited<br />

treatment depth <strong>in</strong> tissue <strong>of</strong> 3 cm.<br />

The highly acclaimed<br />

pr<strong>of</strong>essionalism <strong>and</strong> rigorous efforts<br />

to quality control <strong>the</strong> cl<strong>in</strong>ical<br />

practices at every step made it a<br />

highly successful facility, which<br />

treated one-third <strong>of</strong> eye patients <strong>in</strong><br />

<strong>the</strong> UK <strong>and</strong> dozens <strong>of</strong> patients<br />

across <strong>the</strong> world. It was a busy day<br />

for me. In fact, I was so <strong>in</strong>volved<br />

with <strong>the</strong> <strong>in</strong>tensive discussions that I<br />

forgot my room number when I got<br />

back to my hotel. Luckily I did not<br />

forget which hotel I was stay<strong>in</strong>g <strong>in</strong>!<br />

▼<br />

SCOPE | SEPTEMBER 2012 | 19

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