The North Dakota Nurses - January 2022
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Page 12 <strong>The</strong> <strong>North</strong> <strong>Dakota</strong> Nurse <strong>January</strong>, February, March <strong>2022</strong><br />
Factors Influencing Medication Errors<br />
Anna Holen, Abby Seifert, & Christine Vetsch<br />
BSN Students, University of Jamestown<br />
Editor: Penny Briese, PhD(c), RN<br />
University of Jamestown<br />
Clinical Question: What are some factors that<br />
influence nurses’ medication errors?<br />
Medication safety is a priority for nurses,<br />
considering medication administration<br />
accounts for 40% of the nurse’s occupational<br />
duties and nurses “are responsible for 26-<br />
38% of medication errors” (Dougal, 2020,<br />
p. 7). <strong>The</strong>re are factors that influence and<br />
increase/decrease the chances of making<br />
medication errors. Being aware of these<br />
factors can promote medication safety and<br />
decrease the number of errors that are too<br />
prominently occurring in the nursing field. Six<br />
different articles related to medication errors<br />
in the nursing profession were included in this<br />
miniature literature review.<br />
In 2018, Treiber and Jones performed a<br />
quantitative study in an effort to understand<br />
individual and system level factors that<br />
contribute to medication errors from the<br />
perspective of BSN nursing graduates. <strong>The</strong><br />
researchers investigated perceptions of<br />
adequacy of preparatory nursing education,<br />
contributory variables, emotional responses,<br />
and treatment by employers following the error<br />
(Treiber & Jones, 2018). <strong>The</strong> study consisted<br />
of 168 participants who completed an<br />
online survey. <strong>The</strong> survey was sent out to BSN<br />
graduates from Kennesaw State University in<br />
Georgia who graduated between the years<br />
of 2009-2013. Most of the participants were<br />
white (71%), female (89%), and nearly all were<br />
currently practicing nursing (Treiber & Jones,<br />
2018). More than half of the respondents<br />
indicated they had made a medication error<br />
since becoming a registered nurse; a majority<br />
stated that when they made an error their<br />
facility was supportive. Reasons that a nurse<br />
did not report a medication error included<br />
fear of repercussion, perception the error was<br />
not serious, and the process to report the error<br />
being too time consuming (Treiber & Jones,<br />
2018).<br />
Bekes, Sackash, Voss, and Gill (2021)<br />
focused their study on medication errors<br />
seen specifically in pediatric patients in the<br />
perioperative period. <strong>The</strong> researchers sought<br />
to answer two main questions: 1) what are<br />
the main types of medication errors in the<br />
pediatric population in the perioperative<br />
period, and 2) what mitigation strategies had<br />
the best outcome that can be incorporated<br />
into practice? This was a narrative literature<br />
review of 17 articles. <strong>The</strong> inclusion criteria for<br />
this review included a patient population<br />
from one to 18 years of age, articles printed in<br />
the English language, full-text publications,<br />
and focused on perioperative periods of care<br />
(Bekes et al., 2021). <strong>The</strong> researchers scored<br />
each article using the critical appraisal skills<br />
program qualitative checklist because it<br />
breaks down the methodological approach<br />
to determine the quality of each article.<br />
<strong>The</strong>y found that the most frequent errors<br />
mentioned in the multiple research studies<br />
were incorrect doses (77%) including dilution<br />
errors, calculation errors, and incorrect intervals.<br />
Other examples of common medication errors<br />
included incorrect medication, grabbing the<br />
incorrect syringe, inappropriate medication<br />
labeling, and giving a known allergen (Bekes<br />
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et al., 2021). <strong>The</strong> researchers concluded by<br />
discussing interventions that reduce medication<br />
errors which entailed standardized labeling,<br />
prefilled syringes, two-person checks, drug<br />
library/ electronic-based references, quality<br />
improvement safety analytics, pharmacy<br />
support, computer check systems, staff<br />
education, standardized workspace, zerotolerance<br />
philosophy, and checklists (Bekes et<br />
al., 2021).<br />
Ragau, Hitchcock, Craft, and Christensen<br />
(2018) wanted to look specifically at the<br />
individual human factors that can cause<br />
medication errors. <strong>The</strong>y used the HALT model<br />
(hungry, angry, late, lonely, and tired) to try<br />
and reduce the incidence of medication<br />
errors by 25% by allowing nurses to “be more<br />
aware of how their emotional behavior may<br />
have a deleterious effect” on medication<br />
administration (Ragau et al., 2018, p. 1333).<br />
<strong>The</strong> HALT model was implemented in a 32-bed<br />
acute medical unit. ‘HALT’ posters were placed<br />
throughout the unit to remind the team to<br />
“effectively ‘HALT’ and take time to reflect on<br />
what was occurring for them on an emotional<br />
level and then take the appropriate action”<br />
(Ragau et al., 2018, p. 1333). <strong>The</strong> model was<br />
also used during shift hand-off to highlight any<br />
emotions that needed to be addressed before<br />
the shift change. After the implementation of<br />
the HALT model, there was a decrease in total<br />
medication errors by 31.7% over a two-month<br />
period, a 25.3% decrease in errors relating<br />
to human error, and a 22.9% decrease in<br />
communication and documentation-related<br />
errors (Ragau et al., 2018, p. 1334). Although this<br />
study had a positive response, “caution should<br />
be used when addressing other contributing<br />
factors associated with medication errors as<br />
using HALT alone will not address these” (Ragau<br />
et al., 2018, p. 1334).<br />
Berdot et al. (2021) conducted a study<br />
on nurses wearing a special vest indicating<br />
a time of requested un-interruption. <strong>The</strong>y<br />
analyzed whether the introduction of the vest<br />
reduced medication errors during medication<br />
administration. This was a multicenter,<br />
randomized controlled trial performed in 29<br />
adult units in four hospitals. Over the course of<br />
the study, 178 nurses in 14 units wore a ‘do not<br />
interrupt’ vest during 383 observed medication<br />
rounds to examine the main outcome of<br />
administration error rate. <strong>The</strong> error rate was<br />
defined as “number of Opportunities for Error,<br />
OE, calculated as one or more errors divided by<br />
the Total Opportunities for Error, TOE, multiplied<br />
by 100” (Berdot et al., 2021, p. 1). Berdot et al.<br />
(2021) found that the administration error rates<br />
in the experimental group was 7.09% and 6.23%<br />
in the control group (p. 1). <strong>The</strong> interruption<br />
rates were also similar, with the experimental<br />
group being 15.04% and the control group<br />
being 20.75% (Berdot et al., 2021, p. 6). <strong>The</strong>se<br />
results indicate that the “vest had no impact on<br />
medication administration error or interruption<br />
rates” (Berdot et al., 2021, p. 6).<br />
Dougal (2020) conducted a quantitative nonexperimental<br />
study to determine the perception<br />
of medication administration and medication<br />
errors from registered nurses, related to<br />
the risks, benefits, frequency, and cautions<br />
associated with it. <strong>The</strong> researcher had three<br />
research questions; 1) do nurses perceive risk in<br />
medication administration in everyday practice,<br />
2) how is an RN’s self-reporting behavior related<br />
to medication administration errors and risks,<br />
and 3) do nurses perceive benefit and risk to<br />
medication safety during the administration<br />
process? (Dougal, 2020) This study surveyed<br />
1,445 RN’s using an online seven-point Likert<br />
scale questionnaire. Most RNs reported that<br />
they were “not at all likely” to report medication<br />
errors and believed they do not make errors in<br />
medication administration or are “unlikely” to<br />
do so within the next 12 months (Dougal, 2020,<br />
p. 9). <strong>The</strong>y believe their peers were “very likely”<br />
to make errors in medication administration<br />
within the next 12 months (Dougal, 2020, p. 9).<br />
Most RNs in this study reported not following<br />
proper medication administration processes<br />
due to self-reported distractions, interruptions,<br />
and multi-tasking.<br />
Ekkens and Gordon (2021) conducted a<br />
quantitative quasi-experimental study to<br />
determine if adding mindfulness thinking to<br />
current protocol will eliminate or minimize<br />
medication errors. This study consisted of 111<br />
nurses from rural hospitals located in northern<br />
California. <strong>The</strong> treatment group in this study<br />
received an intervention of mindfulness<br />
training while the control group did not receive<br />
training. “<strong>The</strong> instrument used for the study<br />
was based on the medication error index from<br />
the NCC MERP” (Ekkens et al., 2021, p. 119). This<br />
instrument is designed to categorize medication<br />
errors into nine levels of severity, each level<br />
corresponding to mild, moderate, significant,<br />
or severe severity. <strong>The</strong> researchers found that in<br />
the treatment group, errors were reduced from<br />
15 to four, whereas the control group showed a<br />
reduction in errors from seven to six. <strong>The</strong> result<br />
from this study concludes that “nurses are not<br />
consistently mindful enough when administering<br />
medications; this contributes to errors” (Ekkens<br />
and Gordon, 2021, p. 120). Mindful thinking and<br />
effective training may help to reduce errors and<br />
help nurses focus on the task at hand.<br />
Conclusion<br />
<strong>The</strong>re are many factors that can contribute<br />
to medication errors, but in return there are<br />
many interventions to help decrease the risk of<br />
errors and ensure patient safety. Medication<br />
errors have been studied extensively due<br />
to the danger that errors present to patient<br />
safety. <strong>The</strong> six articles summarized in this<br />
literature review support a numerous array<br />
of interventions that both feed into and can<br />
prevent medication errors. At an educational<br />
level, professors and mentors need to stress the<br />
importance of medication errors and prepare<br />
students for clinical experiences. New nursing<br />
graduates mentioned they should have had<br />
more hands-on experience with medication<br />
administration, especially IV, and time<br />
management skills to encourage effective care<br />
management (Treiber & Jones, 2018). It is highly<br />
recommended that even experienced nurses<br />
should always go through the medication<br />
rights such as correct dose, time, patient, route,<br />
refuse, and medication. <strong>Nurses</strong> should not be<br />
afraid to question doses that seem odd and<br />
they should not solely rely on technology to<br />
recognize mistakes. Facilities should support<br />
nurses in the field because, although reporting<br />
the error can be intimidating, reporting can<br />
help nurse administrators recognize systematic<br />
problems. Not all interventions are helpful and<br />
nurses often blame themselves for medication<br />
errors and feel guilty regardless of whether or<br />
not the error harmed the patient. Hospitals must<br />
find what works best for their individual nurses<br />
because the reasons for medication errors are<br />
quite individualized. Medication errors and<br />
safety continue to be a growing concern in the<br />
healthcare profession.<br />
References<br />
Bekes, J.L., Sackash, C.R., Voss, A.L., & Gill C.J. (2021).<br />
Pediatric medication errors and reduction<br />
strategies in the perioperative period. AANA<br />
Journal 89(4), 319-324.<br />
Berdot, S., Vilfaillot, A., Bezie, Y., Perrin, G., Berge,<br />
M., Corny…Sabatier, B. (2021). Effectiveness<br />
of a ‘do not interrupt’ vest intervention to<br />
reduce medication errors during medication<br />
administration: a multicenter cluster randomized<br />
controlled trial. BMC Nurs, 20(153), 1-11. doi:<br />
10.1186/s12912-021-00671-7<br />
Dougal, R.L. (2020). RN perceptions of medication<br />
administration and medication errors: Results<br />
from a quantitative nursing research study. RN<br />
Idaho, 43(1), 7-9.<br />
Ekkens, C. L. and Gordon, P. A. (2021). <strong>The</strong> mindful<br />
path to nursing accuracy: A quasi-experimental<br />
study on minimizing medication administration<br />
errors. Holistic Nursing Practice, 35(3), 115-122.<br />
doi: 10.1097/HNP.0000000000000440.<br />
Ragau, S., Hitchcock, R., Craft, J., & Christensen.<br />
(2018). Using the HALT model in an<br />
exploratory quality improvement initiative<br />
to reduce medication errors. British Journal<br />
of Nursing, 27(22). 1330-1336. doi: 10.12968/<br />
bjon.2018.27.22.1330<br />
Treiber, L.A. & Jones, J.H. (2018). After the medication<br />
error: Recent nursing graduates’ reflections on<br />
adequacy of education. Journal of Nursing<br />
Education, 57(5), 275-280. doi:10.3928/01484834-<br />
20180420-04