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RESidENcy PROGRAM Scholarly and Community Medicine Projects

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Psychological Assessment cont’d<br />

I need a letter which provides psychological clearance for @FNAME@ to<br />

start hormonal therapy for gender transition. This letter should<br />

include the following:<br />

� Confirmation of diagnosis of gender identity disorder<br />

� Assessment of pt's mental health (i.e. is it stable or improving)<br />

� Assessment of pt's ability to take hormones in a stable manner<br />

� Assessment/discussion of pt's expectations regarding hormone<br />

therapy<br />

� Assessment of any other pschological comorbidities<br />

If *** is not able to provide a letter of clearance, pt will be referred to<br />

Pathways Counselling center in Milwaukee.<br />

Male to Female<br />

Medications<br />

Hormone Therapy<br />

Estrogen: 17B 17B-estradiol estradiol<br />

Transdermal Oral<br />

use if if >40 >40 yrs, yrs, or or at at risk risk If If < < 40 40 yo yo <strong>and</strong> <strong>and</strong> lo lo risk risk<br />

for for DVT DVT<br />

for for DVT DVT<br />

BBr<strong>and</strong> dNName Climara Climara, Vivelle Vivelle, Estradot Estrace<br />

Preorchiectomy<br />

Postorchiectomy<br />

Start 0.1mg/24hrs, twice<br />

weekly; gradually increase<br />

to max 0.2mg/24 hrs twice<br />

weekly<br />

0.375-0.1mg/24 hours,<br />

Applied twice weekly<br />

Start 1-2mg daily,<br />

increase to maximum<br />

4mg daily<br />

1-2mg daily<br />

Monthly Cost $31-60/month generic $11-$18/month generic<br />

Overview<br />

Responsibilities of prescribing clinician (per WPATH):<br />

1. Perform an initial evaluation (H&P, labs)<br />

2. Explain what the hormones do <strong>and</strong> possible side effects/health risks<br />

3. Confirm the pt has the capacity to underst<strong>and</strong> risks/benefits <strong>and</strong><br />

make an informed decision<br />

4. Inform pt of WPATH SOC <strong>and</strong> eligibility/readiness requirements<br />

5. Provide ongoing medical monitoring, including regular physical<br />

exams <strong>and</strong> monitoring labs<br />

Male to Female<br />

Timeline<br />

� 1-6 mos: body fat redistribution, decreased muscle<br />

mass, softer skin, decreased libido, anorgasmia,<br />

decreased ejaculate, decreased erections, testicular<br />

atrophy<br />

� 1-2 mos: breast buds<br />

� Years: hair is finer <strong>and</strong> grows more slowly<br />

Male to Female<br />

Medications (cont’d)<br />

Spironolactone Finasteride<br />

Br<strong>and</strong> Name Aldactone Proscar<br />

Pre-<br />

orchiectomy hi t<br />

Postorchiectomy<br />

Monthly Cost<br />

Start 50-100 daily, 2.5-5.0 mg daily for<br />

increase by 100mg each<br />

month to maximum<br />

systemic anti-<strong>and</strong>rogen<br />

effects<br />

300mg/day (some say 500 2.5 mg every other day if<br />

mg max)<br />

Modify if risk factors<br />

solely for alopecia<br />

<strong>and</strong>rogenetica<br />

0-50 mg daily 2.5 mg daily<br />

200mg daily = $70/month<br />

25mg tabs are on the $4 list<br />

5mg daily-$70/month<br />

5mg tabs are on the $4 list<br />

5/13/2011<br />

6

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