Oral Abstract Session 01 - Global HIV Vaccine Enterprise

PROGRAM / MONDAY
6
Program
13:30 – 14:45 Oral Abstract Session 06: BCEC Level 2,
V1/V2 Antibody Responses Ballroom East
Chairs: Susan Zolla-Pazner and Georgia Tomaras
13:30 – 13:45 A Short Segment in the HIV-1 gp120 V1/V2 Region Is a Major Determinant OA06.01
of Neutralization Resistance to PG9-like Antibodies
NA Doria-Rose, I Georgiev, RP Staupe, S O’Dell, G Chuang, J Gorman,
JS McLellan, M Pancera, M Bonsignori, BF Haynes, DR Burton, WC Koff,
PD Kwong, JR Mascola
13:45 – 14:00 Characterization of V1V2-Specific Antibodies Present in Broadly Neutralizing OA06.02
Plasma Isolated from HIV-1 Infected Individuals
C Krachmarov, K Revesz, R Prattipati, C Reichman, Z Lai, W Honnen, B Li,
C Derdeyn, A Pinter
14:00 – 14:15 Design of an HIV Env Antigen That Binds with High Affinity to OA06.03
Antibodies Against Linear, Conformational and Broadly Neutralizing
Epitopes Within V1/V2
L Liao, M Bonsignori, K Hwang, AM Moody, R Park, S Crawford, H Chen,
TL Jeffries, M Cooper, X Lu, R De, N Karasavvas, S Rerks-Ngarm, S Nitayaphan,
J Kaewkungwal, S Tovanabutra, P Pitisuttithum, J Tartaglia, F Sinangil, J Kim,
NL Michael, GD Tomaras, Z Yang, K Dai, M Pancera, GJ Nabel, JR Mascola,
PD Kwong, A Pinter, S Zolla-Pazner9, MS Alam, BF Haynes
14:15 – 14:30 Evidence for Env-V2 Sieve Effect in Breakthrough SIVMAC251Infections OA06.04
in Rhesus Monkeys Vaccinated with Ad26/MVA and MVA/Ad26 Constructs
S Sina, S Tovanabutra, E Sanders-Buell, A Bates, M Bose, S Howell,
G Ibitamuno, M Lazzaro, A O’Sullivan, J Lee, T Cervenka, J Kuroiwa,
K Baldwin, DH Barouch, M Robb, R O’Connell, NL Michael, JH Kim, M Rolland
14:30 – 14:45 Structural Basis for Germline Gene Usage of a Potent Class of Antibodies OA06.05 LB
Targeting the CD4 Binding Site of HIV-1 gp120
AP West, Jr., R Diskin, MC Nussenzweig, PJ Bjorkman
14:45 – 16:00 Poster Session 1 with Tea and Coffee Break BCEC Level 3,
See inside back cover for the poster presentation schedule. Ballroom West
Poster Discussion 1a: BCEC Level 3,
B Cell Immunology and Antibody Function Ballroom West
Chair: Mattia Bonsignori
15:00 – 15:07 V1/V2-Directed Antibodies Elicited in RV144 Vaccinees Bind to a P03.64 LB
Structurally Polymorphic Site
JS McLellan, J Gorman, M Bonsignori, K Hwang, H Liao, S Rerks-Ngarm,
S Nitayaphan, NL Michael, JH Kim, BF Haynes, PD Kwong
15:07 – 15:14 Structural Definition for a New Modality of Broad and Potent P03.14
Antibody Neutralization at the CD4-binding Site on HIV-1 gp120
T Zhou, S Moquin, R Lynch, X Wu, J Zhu, Y Yang, B Zhang,
JR Mascola, PD Kwong
AIDS Vaccine 2012
Monday, 10 September