PROGRAM / TUESDAY 12 Program 11:45 – 12:00 <strong>HIV</strong> Control Through a Single Nucleotide on the HLA-I Locus OA08.06 H Kløverpris, M Harndahl, J Carlson, A Leslie, M van der Stok, G Huang, F Chen, L Riddell, D Steyn, D Goedhals, C van Vuuren, J Frater, B Walker, T Ndung’u’, S Buus, P Goulder 12:00 – 12:15 Accelerated Heterologous Prime-boost Adenovirus Vector-based SIV OA08.07 <strong>Vaccine</strong> in Neonatal Rhesus Monkeys J Liu, H Li, M Iampietro, DH Barouch 12:15 – 12:30 Intra-dermal Immunisation with SIV Gag-based <strong>Vaccine</strong>s Alone Inhibits OA08.08 Acquisition of SIVmac251 N Almond, R Stebbings, M Page, B Li, N Berry, C Ham, D Ferguson, N Rose, E Mee, C Stahl-Hennig, G Dickson, T Athanasapoulos, A Benlahrech, S Herath, A Meiser, S Patterson 10:30 – 12:30 <strong>Oral</strong> <strong>Abstract</strong> <strong>Session</strong> 09: BCEC Level 2, Clinical Trials Room 253 ABC Chairs: Yiming Shao and Sandhya Vasan 10:30 – 10:45 Safety and Immunogenicity of a Randomized Phase I Prime-boost Trial OA09.<strong>01</strong> with ALVAC-<strong>HIV</strong> (vCP205) and gp160 MN/LAI-2 Adjuvanted in Alum or Polyphosphazene RJ O’Connell, VR Polonis, S Ratto-Kim, J Cox, LL Jagodzinski, J Malia, NL Michael, J Excler, ML Robb, JH Kim 10:45 – 11:00 In Vivo Targeting of <strong>HIV</strong> Gag to Dendritic Cells in Combination with Poly OA09.02 ICLC Is Safe and Immunogenic in Healthy Volunteers M Caskey, C Trumpfheller, S Pollak, L Sinnenberg, A Hurley, J Pring, I Shimeliovich, B Yipp, N Anandasabapathy, S Mehandru, P Sarma, R Koup, R Bailer, G Tomaras, A Sato, T Keler, R Steinman, S Schlesinger 11:00 – 11:15 First-in-Human Phase 1 Trial of the Safety and Immunogenicity of a OA09.03 Recombinant Adenovirus Serotype 5 HVR48 (rAd5HVR48) <strong>HIV</strong>-1 <strong>Vaccine</strong> SR Walsh, MS Seaman, JA Johnson, RP Tucker, KH Krause, M Weijtens, MG Pau, J Goudsmit, R Dolin, DH Barouch, LR Baden 11:15 – 11:30 Antibody-mediated Inhibition of <strong>HIV</strong>-1 Elicited by <strong>HIV</strong>-I DNA Priming and OA09.04 Boosting with Heterologous <strong>HIV</strong>-1 Recombinant MVA in Healthy Tanzanian Adults A Joachim, C Nilsson, S Aboud, M Bakari, EF Lyamuya, M Robb, M Marovich, C Ochsenbauer, B Wahren, F Mhalu, E Sandström, G Biberfeld, G Ferrari, VR Polonis 11:30 – 11:45 A First-in-Man, Double Blind, Placebo Controlled Study of the Candidate OA09.05 Therapeutic <strong>Vaccine</strong> Opal-<strong>HIV</strong>-Gag(c) in <strong>HIV</strong> Infected Patients Receiving HAART AG Jackson, HN Kløverpris, A Handley, P Hayes, J Gilmour, M Atkins, B Walker, J Ackland, M Sullivan, P Goulder 11:45 – 12:00 Multiple Antibody Specificities (gp41, V1V2, and V3) Elicited in the Phase II OA09.06 LB Multiclade (A, B, C) <strong>HIV</strong>-1 DNA Prime, rAd5 Boost <strong>Vaccine</strong> Trial WB Williams, K Jones, A Krambrink, D Grove, P Liu, NL Yates, MA Moody, G Ferrari, J Pollara, Z Moodie, CA Morgan, H Liao, DC Montefiori, C Ochsenbauer, J Kappes, S Hammer, J Mascola, R Koup, L Corey, G Nabel, P Gilbert, G Churchyard, M Keefer, BS Graham, BF Haynes, GD Tomaras AIDS <strong>Vaccine</strong> 2<strong>01</strong>2 Tuesday, 11 September
Tuesday, 11 September AIDS <strong>Vaccine</strong> 2<strong>01</strong>2 Program 12:00 – 12:15 rAd5 Prime/NYVAC-B Boost Regimen is Superior to NYVAC-B Prime/rAd5 OA9.07 LB Boost Regimen for Both Response Rates and Magnitude of CD4 and CD8 T-cell Responses P Bart, Y Huang, N Frahm, S Karuna, M Allen, NK Kochar, S Chappuis, J Gaillard, B Graham, G Pantaleo 12:15 – 12:30 Phase 2a Safety and Immunogenicity Testing of DNA and Recombinant OA09.08 LB Modified Vaccinia Ankara Virus <strong>Vaccine</strong>s Expressing Virus-like Particles P Goepfert, M Elizaga, D Montefiori, J Hural, S DeRosa, G Tomaras, K Seaton, A Sato, L Ouedraogo, Y Donastorg, M Cardinali, J Lama, L Baden, M Keefer, J McElrath, S Kalams, H Robinson 12:30 – 13:30 Lunch BCEC Level 2, Rooms 252 AB / 254 AB / 257 AB 12:30 – 13:30 Networking Lunch BCEC Level 2, Room 259 AB Join us in BCEC Level 2, Room 259 AB where lunch tables have been reserved for young and early-career investigators and community representatives to network with senior researchers. 13:30 – 14:45 <strong>Oral</strong> <strong>Abstract</strong> <strong>Session</strong> 10: BCEC Level 3, <strong>HIV</strong> Transmission / Diversity Chairs: Bette Korber and Zabrina Brumme Room 258 ABC 13:30 – 13:45 Impact of Transmitted CTL Escape Mutations on Replicative Capacity and OA10.<strong>01</strong> <strong>HIV</strong> Pathogenesis in Early Infection J Prince, D Claiborne, D Heckerman, J Carlson, H Prentice, M Schaefer, L Yue, J Mulenga, J Tang, P Goepfert, P Farmer, R Kaslow, S Allen, E Hunter 13:45 – 14:00 A Deeper View of Transmitted/Founder Viruses Using 454 Whole OA10.02 Genome Deep Sequencing DC Tully, KA Power, H Bedard, CL Boutwell, P Charlebois, EM Ryan, NJ Lennon, M Altfeld, MR Henn, TM Allen 14:00 – 14:15 Modeling Virus Exposure During Male to Female Transmission of <strong>HIV</strong>-1 OA10.03 A Carias, M McRaven, M Anderson, RS Veazey, TJ Hope 14:15 – 14:30 Beneficial HLA-mediated Viral Polymorphisms on the Transmitted Virus OA10.04 Additively Influence Disease Progression in <strong>HIV</strong>-1, Subtype C Infection RS Ntale, DR Chopera, NK Ngandu, M Abrahams, A Debra, M Mlotswa, L Werner, Z Woodman, K Mlisana, S Abdool Karim, CM Gray, C Williamson, CAPRISA 002 AI Study Team 14:30 – 14:45 T-cell Based Sieve Analysis Ties HLA A*02 to <strong>Vaccine</strong> Efficacy and IgA-C1 OA10.05 LB Immune Correlate in RV144 Thai Trial T Hertz, A Gartland, H Janes, S Li, Y Fong, GD Tomaras, D Morris, D Geraghty, GH Kijak, PT Edlefsen, M Rolland, BB Larsen, S Tovanabutra, E Sanders-Buell, AC DeCamp, CA Magaret, H Ahmed, S Nariya, K Wong, H Zhao, W Deng, BS Maust, M Bose, S Howell, M Lazzaro, A Bates, E Lei, A Bradfield, G Ibitamuno, V Assawadarachai, RJ O’Connel, MS deSouza, S Nitayaphan, S Rerks-Ngarm, ML Robb, MJ McElrath, BF Haynes, NL Michael, PB Gilbert, JI Mullins, JH Kim 13 PROGRAM / TUESDAY
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- Page 36 and 37: PLENARY SESSIONS 24 Plenary Session
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92 AIDS Vaccine 2012
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POSTERS 94 AIDS Vaccine 2012
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POSTERS 96 Posters Topic 1: Adjuvan
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POSTERS 98 Posters Topic 1: Adjuvan
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POSTERS Posters Topic 1: Adjuvants,
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POSTERS Posters Topic 2: Animal Mod
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POSTERS Posters Topic 3: B Cell Imm
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POSTERS Posters Topic 4: Clinical V
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POSTERS Posters Topic 5: HIV Transm
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POSTERS Posters Topic 6: Immunogene
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POSTERS Posters Topic 12: Vaccine C
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AUTHOR INDEX Author Index Brander,
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AUTHOR INDEX Author Index Guan, Y .
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AUTHOR INDEX Author Index Lucas, J.
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AUTHOR INDEX Author Index Quinn, T
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AUTHOR INDEX Author Index Wendel-Ha
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Notes 288
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Notes 290
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Poster Session 1 - Monday, 10 Septe