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Oral Abstract Session 01 - Global HIV Vaccine Enterprise

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Tuesday, 11 September<br />

AIDS <strong>Vaccine</strong> 2<strong>01</strong>2<br />

Program<br />

12:00 – 12:15 rAd5 Prime/NYVAC-B Boost Regimen is Superior to NYVAC-B Prime/rAd5 OA9.07 LB<br />

Boost Regimen for Both Response Rates and Magnitude of CD4 and CD8<br />

T-cell Responses<br />

P Bart, Y Huang, N Frahm, S Karuna, M Allen, NK Kochar, S Chappuis,<br />

J Gaillard, B Graham, G Pantaleo<br />

12:15 – 12:30 Phase 2a Safety and Immunogenicity Testing of DNA and Recombinant OA09.08 LB<br />

Modified Vaccinia Ankara Virus <strong>Vaccine</strong>s Expressing Virus-like Particles<br />

P Goepfert, M Elizaga, D Montefiori, J Hural, S DeRosa, G Tomaras,<br />

K Seaton, A Sato, L Ouedraogo, Y Donastorg, M Cardinali, J Lama,<br />

L Baden, M Keefer, J McElrath, S Kalams, H Robinson<br />

12:30 – 13:30 Lunch BCEC Level 2, Rooms 252 AB / 254 AB / 257 AB<br />

12:30 – 13:30 Networking Lunch BCEC Level 2, Room 259 AB<br />

Join us in BCEC Level 2, Room 259 AB where lunch tables have been reserved for young and<br />

early-career investigators and community representatives to network with senior researchers.<br />

13:30 – 14:45 <strong>Oral</strong> <strong>Abstract</strong> <strong>Session</strong> 10: BCEC Level 3,<br />

<strong>HIV</strong> Transmission / Diversity<br />

Chairs: Bette Korber and Zabrina Brumme<br />

Room 258 ABC<br />

13:30 – 13:45 Impact of Transmitted CTL Escape Mutations on Replicative Capacity and OA10.<strong>01</strong><br />

<strong>HIV</strong> Pathogenesis in Early Infection<br />

J Prince, D Claiborne, D Heckerman, J Carlson, H Prentice, M Schaefer,<br />

L Yue, J Mulenga, J Tang, P Goepfert, P Farmer, R Kaslow, S Allen, E Hunter<br />

13:45 – 14:00 A Deeper View of Transmitted/Founder Viruses Using 454 Whole OA10.02<br />

Genome Deep Sequencing<br />

DC Tully, KA Power, H Bedard, CL Boutwell, P Charlebois, EM Ryan,<br />

NJ Lennon, M Altfeld, MR Henn, TM Allen<br />

14:00 – 14:15 Modeling Virus Exposure During Male to Female Transmission of <strong>HIV</strong>-1 OA10.03<br />

A Carias, M McRaven, M Anderson, RS Veazey, TJ Hope<br />

14:15 – 14:30 Beneficial HLA-mediated Viral Polymorphisms on the Transmitted Virus OA10.04<br />

Additively Influence Disease Progression in <strong>HIV</strong>-1, Subtype C Infection<br />

RS Ntale, DR Chopera, NK Ngandu, M Abrahams, A Debra, M Mlotswa,<br />

L Werner, Z Woodman, K Mlisana, S Abdool Karim, CM Gray, C Williamson,<br />

CAPRISA 002 AI Study Team<br />

14:30 – 14:45 T-cell Based Sieve Analysis Ties HLA A*02 to <strong>Vaccine</strong> Efficacy and IgA-C1 OA10.05 LB<br />

Immune Correlate in RV144 Thai Trial<br />

T Hertz, A Gartland, H Janes, S Li, Y Fong, GD Tomaras, D Morris, D Geraghty,<br />

GH Kijak, PT Edlefsen, M Rolland, BB Larsen, S Tovanabutra, E Sanders-Buell,<br />

AC DeCamp, CA Magaret, H Ahmed, S Nariya, K Wong, H Zhao, W Deng,<br />

BS Maust, M Bose, S Howell, M Lazzaro, A Bates, E Lei, A Bradfield,<br />

G Ibitamuno, V Assawadarachai, RJ O’Connel, MS deSouza, S Nitayaphan,<br />

S Rerks-Ngarm, ML Robb, MJ McElrath, BF Haynes, NL Michael, PB Gilbert,<br />

JI Mullins, JH Kim<br />

13<br />

PROGRAM / TUESDAY

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