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Oral Abstract Session 01 - Global HIV Vaccine Enterprise

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PROGRAM / TUESDAY<br />

14<br />

Program<br />

13:30 – 14:45 <strong>Oral</strong> <strong>Abstract</strong> <strong>Session</strong> 11: BCEC Level 2,<br />

<strong>Vaccine</strong> Immunogens / Delivery Ballroom East<br />

Chairs: Harriet Robinson and Sallie Permar<br />

13:30 – 13:45 <strong>HIV</strong>-1 Envelope Trimer Elicits Higher Neutralizing Antibody Responses OA11.<strong>01</strong><br />

Than Monomeric gp120<br />

JM Kovacs, JP Nkolola, H Peng, A Cheung, J Perry, CA Miller, MS Seaman,<br />

D Barouch, B Chen<br />

13:45 – 14:00 Shaping Humoral Responses Against Mini-libraries of <strong>HIV</strong> Env Antigens via OA11.02<br />

Lipid Nanoparticle <strong>Vaccine</strong> Delivery<br />

MC Hanson, J Mata-Fink, W Abraham, KD Wittrup, DJ Irvine<br />

14:00 – 14:15 <strong>Vaccine</strong> Responses to Conserved Regions of the <strong>HIV</strong>-1 Proteome Are OA11.03<br />

Associated with an Increased Capacity to Inhibit Multiple Virus Isolates<br />

Ex Vivo<br />

A Ashraf, J Kopycinski, H Cheeseman, F Lala, J Czyzewska-Khan, A Spentzou,<br />

DK Gill, M Keefer, J Excler, P Fast, P Hayes, JH Cox, J Gilmour<br />

14:15 – 14:30 Antigen-specific T Lymphocyte Responses Elicited by a DNA – MVA <strong>HIV</strong> OA11.04<br />

CN54gp140 Immunization Regime Are Significantly Altered by the TLR4<br />

Adjuvant GLA<br />

PF McKay, AV Cope, J Swales, S Joseph, M Esteban, R Tatoud, D Carter,<br />

J Weber, RJ Shattock<br />

14:30 – 14:45 Quality of T-cell Responses Versus Reduction in Viral Load: Results from an OA11.05 LB<br />

Exploratory Phase II Clinical Study of Vacc-4x, a Therapeutic <strong>HIV</strong> <strong>Vaccine</strong><br />

K Ellefsen-Lavoie, J Rockstroh, R Pollard, G Pantaleo, D Podzamczer, D Asmuth,<br />

J van Lunzen, K Arastéh, D Schürmann, B Peters, B Clotet, D Hardy, A Lazzarin,<br />

J Gatell, MA Sommerfelt, I Baksaas, V Wendel-Hansen, B Sørensen<br />

13:30 – 14:45 <strong>Oral</strong> <strong>Abstract</strong> <strong>Session</strong> 12: BCEC Level 2,<br />

<strong>Vaccine</strong> Concepts – Vectors and Inserts Room 253 ABC<br />

Chairs: Punnee Pitisuttithum and Karin Lore<br />

13:30 – 13:45 DNA <strong>Vaccine</strong>s Expressing Conserved Elements Provide Potent and Broad OA12.<strong>01</strong><br />

Immune Responses<br />

GN Pavlakis, V Kulkarni, A Valentin, M Rosati, NY Sardesai, B Mothe,<br />

C Brander, S LeGall, DB Weiner, M Rolland, JI Mullins, BK Felber<br />

13:45 – 14:00 Reinventing the Nucleic Acid <strong>Vaccine</strong> with Self-amplifying RNA OA12.02<br />

AJ Geall, GR Otten, A Hekele, W Bogers, H Oostermeijer, P Mooij,<br />

K Gerrit, E Verschoor, K Banerjee, Y Cu, CW Beard, LA Brito, JB Ulmer,<br />

CW Mandl, SW Barnett<br />

14:00 – 14:15 Adenovirus Serotype 26 Utilizes CD46 as Primary Cellular Receptor and OA12.03<br />

Only Transiently Activates T Lymphocytes Following Vaccination of<br />

Rhesus Monkeys<br />

H Li, EG Rhee, K Masek-Hammerman, JE Teigler, P Abbink, DH Barouch<br />

AIDS <strong>Vaccine</strong> 2<strong>01</strong>2<br />

Tuesday, 11 September

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