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Gastroenterology Today Summer 2022

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NEWS<br />

ASSESSING STOMACH HEALTH TO IMPROVE<br />

GASTRIC CANCER DIAGNOSIS<br />

Chronic gastrointestinal problems can signal something<br />

serious, such as atrophic gastritis (AG) or gastric intestinal<br />

metaplasia – both neoplastic conditions – which are often<br />

initiated by Helicobacter pylori infection. There are currently<br />

several methods to diagnose H. pylori, including a stool<br />

antigen test or urea breath test, which do not show the level<br />

of mucosal damage from AG, or gastroscopy, an invasive<br />

procedure that often has long waiting lists. From a clinical<br />

point of view, it is vital to identify AG as early as possible, as it<br />

is a significant risk factor for gastric cancer, a condition that is<br />

often diagnosed at a late stage – carrying an abysmal five year<br />

survival rate of 20.7 % in the UK – and requires surveillance.<br />

The recent guidelines from the British Society of<br />

<strong>Gastroenterology</strong> (BSG) recommend that the key to early<br />

cancer detection is to non-invasively detect pre-cancerous<br />

conditions before endoscopy. However, the current diagnostic<br />

pathway for patients presenting with stomach complaints<br />

is ambiguous, and they often remain in primary care too<br />

long – delaying diagnosis – or are referred too soon, where<br />

gastroscopy identifies no pathology. BIOHIT HealthCare Ltd<br />

has developed a test to help screen these high risk patients<br />

in primary care, enabling GPs to confidently identify patients<br />

who can be managed symptomatically, or otherwise should be<br />

referred to a specialist for gastroscopy.<br />

provides results in just 15 minutes, enabling quick and reliable<br />

diagnosis of both symptomatic and asymptomatic patients<br />

with stomach problems. This can help identify patients with<br />

AG sooner, and with comparable accuracy to the current gold<br />

standard methods – gastroscopy and histology – to select<br />

patients that require further examination.<br />

The GastroPanel Quick Test is a cost-effective method that helps<br />

to improve the management of patients with gastrointestinal<br />

problems. Importantly, it bridges the gap in the diagnostic<br />

pathway, potentially identifying pre-neoplastic conditions in<br />

primary care, and increasing the diagnostic yield in secondary<br />

care by only referring patients in the higher risk category. This<br />

could lead to more gastric cancers being detected at an earlier,<br />

more curable stage, while at the same time reducing both the<br />

cost and volume burden on healthcare resources.<br />

The GastroPanel Quick Test is now available in the UK. For more<br />

information visit our website biohithealthcare.co.uk or see us in<br />

person at stand A56 at BSG Live 22 for a live demonstration of<br />

the GastroPanel Quick Test.<br />

For more information about GastroPanel<br />

contact: info@biohithealthcare.co.uk<br />

The GastroPanel ® Quick Test is a non-invasive blood test<br />

that investigates H. pylori infection and measures three<br />

stomach-specific biomarkers – pepsinogen I, pepsinogen II<br />

and gastrin-17 – to rapidly detect AG, offering more decisive<br />

clinical information compared to an H. pylori test alone. It<br />

can easily be performed during a clinical appointment, and<br />

GASTROENTEROLOGY TODAY - SUMMER <strong>2022</strong><br />

For the early diagnosis<br />

of gastric cancer risk<br />

Reduce endoscopy waiting lists and<br />

improve the diagnostic pathway for<br />

patients, through an earlier, faster<br />

and more cost-effective approach.<br />

20<br />

www.biohithealthcare.co.uk

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