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Current Cancer Research For other t
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Editor Marcelo G. Kazanietz, Ph.D.
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Contents Part I Regulation of PKC I
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Contents 21 PKC and Resistance to C
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xii Contributors Maria T. Diaz-Meco
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xiv Contributors Lauren Van Wassenh
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Chapter 1 Protein Kinase C in Cance
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1 Protein Kinase C in Cancer Signal
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1 Protein Kinase C in Cancer Signal
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Chapter 2 Regulation of Conventiona
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2 Regulation of Conventional and No
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2 Regulation of Conventional and No
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2 Regulation of Conventional and No
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2 Regulation of Conventional and No
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2 Regulation of Conventional and No
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2 Regulation of Conventional and No
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2 Regulation of Conventional and No
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26 P.M. Blumberg et al. 3.1 Introdu
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28 P.M. Blumberg et al. 1981; Diamo
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30 P.M. Blumberg et al. 3.4 DAG-Lac
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32 P.M. Blumberg et al. 3.6 Role of
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34 P.M. Blumberg et al. Interesting
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36 P.M. Blumberg et al. the proximi
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38 P.M. Blumberg et al. 3.14 C1 Dom
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40 P.M. Blumberg et al. the A and B
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42 P.M. Blumberg et al. The above r
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44 P.M. Blumberg et al. 3.19 Role o
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46 P.M. Blumberg et al. 3.20 Conclu
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48 P.M. Blumberg et al. Churchill,
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50 P.M. Blumberg et al. the isoster
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52 P.M. Blumberg et al. Pu, Y., Pea
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Chapter 4 Diacylglycerol Signaling:
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4 Diacylglycerol Signaling OH O P D
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4 Diacylglycerol Signaling intermed
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4 Diacylglycerol Signaling cPKC (α
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4 Diacylglycerol Signaling 4.3 DAG
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4 Diacylglycerol Signaling DGKα DG
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4 Diacylglycerol Signaling the spat
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4 Diacylglycerol Signaling adhesion
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4 Diacylglycerol Signaling prolifer
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4 Diacylglycerol Signaling Gomez-Me
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4 Diacylglycerol Signaling Maruyama
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4 Diacylglycerol Signaling Cepsilon
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Chapter 5 Regulation of PKC by Prot
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5 Regulation of PKC by Protein-Prot
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5 Regulation of PKC by Protein-Prot
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5 Regulation of PKC by Protein-Prot
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5 Regulation of PKC by Protein-Prot
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5 Regulation of PKC by Protein-Prot
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5 Regulation of PKC by Protein-Prot
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5 Regulation of PKC by Protein-Prot
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5 Regulation of PKC by Protein-Prot
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5 Regulation of PKC by Protein-Prot
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5 Regulation of PKC by Protein-Prot
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5 Regulation of PKC by Protein-Prot
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5 Regulation of PKC by Protein-Prot
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Chapter 6 Introduction: PKC Isozyme
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6 Introduction: PKC Isozymes in the
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6 Introduction: PKC Isozymes in the
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6 Introduction: PKC Isozymes in the
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6 Introduction: PKC Isozymes in the
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118 E. Rozengurt Keywords Protein k
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120 E. Rozengurt The initial descri
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122 E. Rozengurt mechanisms, involv
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124 E. Rozengurt PKC DAG DAG P Ser
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8 PKC and Control of the Cell Cycle
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8 PKC and Control of the Cell Cycle
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8 PKC and Control of the Cell Cycle
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8 PKC and Control of the Cell Cycle
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8 PKC and Control of the Cell Cycle
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8 PKC and Control of the Cell Cycle
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Chapter 9 PKC and the Control of Ap
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9 PKC and the Control of Apoptosis
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9 PKC and the Control of Apoptosis
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9 PKC and the Control of Apoptosis
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9 PKC and the Control of Apoptosis
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9 PKC and the Control of Apoptosis
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9 PKC and the Control of Apoptosis
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9 PKC and the Control of Apoptosis
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9 PKC and the Control of Apoptosis
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9 PKC and the Control of Apoptosis
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9 PKC and the Control of Apoptosis
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9 PKC and the Control of Apoptosis
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9 PKC and the Control of Apoptosis
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9 PKC and the Control of Apoptosis
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9 PKC and the Control of Apoptosis
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9 PKC and the Control of Apoptosis
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9 PKC and the Control of Apoptosis
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Chapter 10 Atypical PKCs, NF-kB, an
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10 Atypical PKCs, NF-kB, and Inflam
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10 Atypical PKCs, NF-kB, and Inflam
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10 Atypical PKCs, NF-kB, and Inflam
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10 Atypical PKCs, NF-kB, and Inflam
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10 Atypical PKCs, NF-kB, and Inflam
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10 Atypical PKCs, NF-kB, and Inflam
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10 Atypical PKCs, NF-kB, and Inflam
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10 Atypical PKCs, NF-kB, and Inflam
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10 Atypical PKCs, NF-kB, and Inflam
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10 Atypical PKCs, NF-kB, and Inflam
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Part III PKC Isozymes in Cancer
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248 M.G. Kazanietz to NIH 3T3 cells
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250 M.G. Kazanietz Kiley, S. C., Cl
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Chapter 12 Protein Kinase C, p53, a
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12 Protein Kinase C, p53, and DNA D
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12 Protein Kinase C, p53, and DNA D
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12 Protein Kinase C, p53, and DNA D
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12 Protein Kinase C, p53, and DNA D
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12 Protein Kinase C, p53, and DNA D
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12 Protein Kinase C, p53, and DNA D
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268 N.A. Riobo PTCH Patched SMO Smo
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270 N.A. Riobo OFF Hh ON N PATCHED
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272 N.A. Riobo 13.3 Hedgehog Signal
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274 N.A. Riobo the activation of Gl
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276 N.A. Riobo vertebrates in a b-c
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278 N.A. Riobo numerous colon polyp
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280 N.A. Riobo It is remarkable tha
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282 N.A. Riobo Some Wnt isoforms, k
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284 N.A. Riobo James, R.G., Conrad,
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286 N.A. Riobo Rohatgi, R., Milenko
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288 Q.J. Wang (Blumberg 1988). DAG
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290 Q.J. Wang Gbg PKCh PKD PI4K III
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292 Q.J. Wang 2003b). At the mitoch
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294 Q.J. Wang tumors and their prop
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296 Q.J. Wang regulating integrin r
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298 Q.J. Wang 14.6 Concluding Remar
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300 Q.J. Wang Harrison, B. C., Kim,
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302 Q.J. Wang Storz, P., Doppler, H
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Chapter 15 Transgenic Mouse Models
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15 Transgenic Mouse Models to Inves
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15 Transgenic Mouse Models to Inves
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15 Transgenic Mouse Models to Inves
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15 Transgenic Mouse Models to Inves
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15 Transgenic Mouse Models to Inves
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15 Transgenic Mouse Models to Inves
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15 Transgenic Mouse Models to Inves
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15 Transgenic Mouse Models to Inves
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324 M.F. Denning common subtype of
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326 M.F. Denning Fig. 16.1 PKC isoz
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328 M.F. Denning and CXCR2 ligands
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330 M.F. Denning Fig. 16.2 Model of
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332 M.F. Denning 16.3 Basal Cell Ca
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334 M.F. Denning Fig. 16.3 PKC in m
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336 M.F. Denning some benign nevi a
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338 M.F. Denning Cataisson, C., Pea
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340 M.F. Denning Gilhooly, E. M., M
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342 M.F. Denning Nishizuka, Y. (198
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344 M.F. Denning Sikkink, S. K., Re
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Chapter 17 PKC and Breast Cancer *
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17 PKC and Breast Cancer Relative E
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17 PKC and Breast Cancer The array
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17 PKC and Breast Cancer 17.7 Growt
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17 PKC and Breast Cancer showed tha
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17 PKC and Breast Cancer de Vente,
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17 PKC and Breast Cancer Palmantier
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Chapter 18 PKC and Prostate Cancer
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18 PKC and Prostate Cancer In Dunni
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18 PKC and Prostate Cancer may be c
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18 PKC and Prostate Cancer an inhib
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18 PKC and Prostate Cancer protein-
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18 PKC and Prostate Cancer expressi
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18 PKC and Prostate Cancer PKCbII a
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18 PKC and Prostate Cancer Gonzalez
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18 PKC and Prostate Cancer Sakamoto
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Chapter 19 Protein Kinase C and Lun
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19 Protein Kinase C and Lung Cancer
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19 Protein Kinase C and Lung Cancer
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19 Protein Kinase C and Lung Cancer
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19 Protein Kinase C and Lung Cancer
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19 Protein Kinase C and Lung Cancer
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19 Protein Kinase C and Lung Cancer
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19 Protein Kinase C and Lung Cancer
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19 Protein Kinase C and Lung Cancer
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19 Protein Kinase C and Lung Cancer
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19 Protein Kinase C and Lung Cancer
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Chapter 20 Introduction Patricia S.
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20 Introduction The first compound
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20 Introduction Tamaoki, T., & Naka
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410 A. Basu DNA. Because chemothera
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412 A. Basu to doxorubicin was asso
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414 A. Basu PKC in vitro (Chambers
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416 A. Basu decreasing the levels o
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418 A. Basu of cisplatin-sensitive
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420 A. Basu 21.3.4 Mechanism of PKC
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422 A. Basu In contrast, PKCi but n
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424 A. Basu Brodie, C., & Blumberg,
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426 A. Basu Higgins, C. F. (1993).
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428 A. Basu Pulaski, L., Szemraj, J
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Chapter 22 PKCd as a Target for Che
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22 PKCd as a Target for Chemotherap
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22 PKCd as a Target for Chemotherap
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22 PKCd as a Target for Chemotherap
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22 PKCd as a Target for Chemotherap
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22 PKCd as a Target for Chemotherap
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22 PKCd as a Target for Chemotherap
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22 PKCd as a Target for Chemotherap
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22 PKCd as a Target for Chemotherap
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22 PKCd as a Target for Chemotherap
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22 PKCd as a Target for Chemotherap
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22 PKCd as a Target for Chemotherap
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456 V. Justilien and A.P. Fields fa
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458 V. Justilien and A.P. Fields By
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460 V. Justilien and A.P. Fields In
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462 V. Justilien and A.P. Fields en
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464 V. Justilien and A.P. Fields A
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466 V. Justilien and A.P. Fields sm
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468 V. Justilien and A.P. Fields PK
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470 V. Justilien and A.P. Fields 23
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472 V. Justilien and A.P. Fields in
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474 V. Justilien and A.P. Fields pr
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476 V. Justilien and A.P. Fields un
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478 V. Justilien and A.P. Fields Ad
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480 V. Justilien and A.P. Fields Go
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482 V. Justilien and A.P. Fields Mu
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484 V. Justilien and A.P. Fields Wa
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486 Index Apoptotic effectors, 192
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488 Index Cell survival (cont.) pro
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490 Index Lung cancer (cont.) physi
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492 Index Proliferation and cell-cy
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494 Index Tumor suppression and pro