26.12.2012 Views

Diacylglycerol Signaling

Diacylglycerol Signaling

Diacylglycerol Signaling

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

13 PKCs as Mediators of the Hedgehog and Wnt <strong>Signaling</strong> Pathways<br />

Medina, A., Reintsch, W., Steinbeisser, H. (2000). Xenopus frizzled 7 can act in canonical and<br />

non-canonical Wnt signaling pathways: implications on early patterning and morphogenesis.<br />

Mech Dev, 92,227–237.<br />

Methot, N., Basler, K. (2000). Suppresor of fused opposes hedgehog signal transduction by impeding<br />

nuclear accumulation of the activator form of Cubitus interruptus. Development,<br />

127,4001–4010.<br />

Mikels, A.J., Nusse, R. (2006). Wnts as ligands: processing, secretion and reception. Oncogene,<br />

25,7461–7468.<br />

Moon, R.T., Campbell, R.M., Christian, J.L., McGrew, L.L., Shih, J., Fraser, S. (1993). Xwnt-5A:<br />

a maternal Wnt that affects morphogenetic movements after overexpression in embryos of<br />

Xenopus leavis. Development, 11,97–111.<br />

Morin, P.J., Sparks, A.B., Korinek, V., Barker, N., Clevers, H., Vogelstein, B., et al. (1997).<br />

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC.<br />

Science, 275,1787–1790.<br />

Neill, G.W., Ghali, L.R., Green, J.L., Philpott, M.P., Quinn, A.G. (2003). Loss of protein kinase<br />

C alpha expression may enhance the tumorigenic potential of Gli1 in basal cell carcinoma.<br />

Cancer Res, 63,4692–4697<br />

Newton, A.C. (1997). Regulation of protein kinase C. Curr Opin Cell Bio,l 9,161–167.<br />

Nilsson, M., Undèn, A.B., Krause, D.,Malmqwist, U., Raza, K., Zaphiropoulos, P.G., Toftgård, R.<br />

(2000). Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-<br />

1. Proc Natl Acad Sci USA, 97,3438–3443.<br />

Nishisho, I., Nakamura, Y., Miyoshi, Y., Miki, Y., Ando, H., Horii, A., et al. (1991). Mutations of<br />

chromosome 5q21 genes in FAP and colorectal cancer patients. Science, 253,665–669.<br />

Nusse, R., Varmus, H.E. (1982). Many tumors induced by the mouse mammary tumor virus contain<br />

a provirus integrated in the same region of the host genome. Cell, 31,99–109.<br />

Nusse, R., Varmus, H.E. (1992). Wnt genes. Cell, 69,1073–1087.<br />

Nüsslein-Volhard, C., Wieschaus, E. (1980). Mutations affecting segment number and polarity in<br />

Drosophila. Nature, 287,795–801.<br />

Ogden, S.K., Fei, D.L., Schilling, N.S., Ahmed, Y.F., Hwa, J., Robbins, D.J. (2008) G protein<br />

Galphai functions immediately downstream of Smoothened in Hedgehog signaling. Nature,<br />

456,967–970.<br />

Pan, Y., Bai, C.B., Joyner, A.L., Wang, B. (2006). Sonic hedgehog signaling regulates Gli2<br />

transcriptional activity by suppressing its processing and degradation. Mol Cell Biol,<br />

26,3365–3377.<br />

Pandur, P., Läsche, M., Eisenberg, L.M., Kühl, M. (2002). Wnt-11 activation of a non-canonical<br />

Wnt signalling pathway is required for cardiogenesis. Nature, 418,636–641.<br />

Penzo-Mendez, A., Umbhauer, M., Djiane, A., Boucaut, J.C., Riou, J.F. (2003). Activation of<br />

Gbetagamma signaling downstream of Wnt-11/Xfz7 regulates Cdc42 activity during Xenopus<br />

gastrulation. Dev Biol, 257:302–314.<br />

Rijsewijk, F., Schuermann, M., Wagenaar, E., Parren, P., Weigel, D., Nusse, R. (1987). The<br />

Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity<br />

gene wingless. Cell 50,649–57.<br />

Riobo, N.A., Lu, K., Emerson, C.P. Jr. (2006a). Hedgehog signal transduction: signal integration<br />

and crosstalk in development and cancer. Cell Cycle, 5,1612–1615.<br />

Riobo, N.A., Lu, K., Ai, X., Haines, G.M., Emerson, C.P. Jr. (2006b). Phosphoinositide 3-kinase<br />

and Akt are essential for Sonic Hedgehog signaling. Proc Natl Acad Sci USA, 103,<br />

4505–4510<br />

Riobo, N.A., Saucy, B., DiLizzio, C., Manning, D.R. (2006c). Activation of heterotrimeric G<br />

proteins by Smoothened. Proc Natl Acad Sci USA, 103,12607–12612.<br />

Riobo, N.A., Haines, G.M., Emerson, C.P. Jr. (2006d). Protein kinase C-delta and mitogen-activated<br />

protein/extracellular signal-regulated kinase-1 control GLI activation in Hedgehog signaling.<br />

Cancer Res, 66,839–845.<br />

Riobo, N.A., Manning, D.R. (2007). Pathways of signal transduction employed by vertebrate<br />

Hedgehogs. Biochem J, 403,369–379.<br />

285

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!