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Oscillations, Waves, and Interactions - GWDG

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Dynamics of pulsed laser tissue ablation 237<br />

Figure 12. Early phase of water ablation by a Q-switched Er:YAG laser pulse of 70 ns<br />

duration, photographed using a novel white light Schlieren technique [76]. The irradiated<br />

spot size was 700 µm, the radiant exposure 2.8 J/cm 2 (25× ablation threshold). All times<br />

refer to the beginning of the laser pulse. The dynamics is characterized by vapour plume<br />

formation, the emission of external <strong>and</strong> internal shock waves, droplet ejection, <strong>and</strong> the onset<br />

of recoil-induced material expulsion.<br />

To date, most investigations of the plume dynamics <strong>and</strong> acoustic phenomena associated<br />

with pulsed laser ablation of biological tissues have been performed experimentally<br />

by time-resolved photography, probe beam deflectometry, <strong>and</strong> spectroscopic<br />

techniques as reviewed in Refs. [6] <strong>and</strong> [76]. Here, we focus on the description of the<br />

plume dynamics itself rather than on the techniques of investigation. We first discuss<br />

the dynamics for water ablation <strong>and</strong> then progress to the more complicated case<br />

of tissue ablation where the primary ablation process <strong>and</strong> recoil-induced material<br />

expulsion are modified by the tissue matrix.<br />

5.1 Primary material ejection in nanosecond ablation<br />

For Q-switched laser pulses of 50–100 ns duration, the rate of energy deposition is<br />

extremely large. Close to threshold, the ablation process for liquids such as water<br />

is typically characterized by non-equilibrium mass transfer [52] at the target surface<br />

followed by a phase explosion of the superficial liquid layer [37]. However, when pulse<br />

energies well above the ablation threshold are used, large volumetric energy densities<br />

are produced in the target material that result in an ablation process characterized by<br />

more vigorous types of phase transitions. To illustrate this, Fig. 12 shows the sequence

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