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Lot's Wife Edition 1 2016

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The skinny on<br />

gluten-free diets<br />

SCIENCE<br />

By Anastasia Goutzoulas<br />

Where cutting out fat was once considered<br />

the silver bullet for perfect health, a<br />

gluten-free diet is now seen as a cure-all.<br />

But what is gluten, really? And is it all<br />

that bad for you?<br />

WHAT IS GLUTEN?<br />

Chemically speaking, gluten is a network of<br />

two protein types, glutenin and gliadin. In dry fl ours,<br />

these exist separately. Adding water makes these<br />

proteins form chemical links (disulphide bonds) with<br />

one another, and kneading or mixing forms even<br />

more bonds. These bonds make the resulting gluten<br />

network strong and elastic.<br />

Gluten can be found in foods containing wheat,<br />

barley and rye. This is a really broad category, and<br />

includes pasta, noodles, condiments, many prepackaged<br />

snacks, and beer.<br />

TO EAT OR NOT TO EAT?<br />

Coeliac disease?<br />

Coeliac disease is an autoimmune disease<br />

that presents as a response to the gliadin protein in<br />

gluten in the small intestine of a sensitive person.<br />

That is, the body of a coeliac sufferer mounts an<br />

immune response to the presence of gliadin in<br />

the small intestine, in the same way that it would<br />

initiate an immune response to fi ght off an infection.<br />

It produces antibodies that attack the gliadin<br />

molecule, an otherwise harmless protein.<br />

As a result, coeliacs suffer infl ammation<br />

and damage to the lining of the small intestine.<br />

Coeliac disease can be diagnosed by a doctor after<br />

a blood test to check for antibodies known as tissue<br />

transglutaminase antibodies (tTG-IgA), as well as a<br />

series of other tests for patients who may be at risk<br />

of returning a false positive on the tTG-IgA test (such<br />

as Type 1 diabetics and people with rheumatoid<br />

arthritis, both also autoimmune diseases). This is<br />

followed up by a biopsy to see if the lining of your<br />

small intestine is damaged.<br />

For coeliacs, gluten really is that bad, at any<br />

level. No cheat meals allowed here – even trace<br />

Lot’s <strong>Wife</strong> | 41

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