Lot's Wife Edition 1 2016
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The skinny on<br />
gluten-free diets<br />
SCIENCE<br />
By Anastasia Goutzoulas<br />
Where cutting out fat was once considered<br />
the silver bullet for perfect health, a<br />
gluten-free diet is now seen as a cure-all.<br />
But what is gluten, really? And is it all<br />
that bad for you?<br />
WHAT IS GLUTEN?<br />
Chemically speaking, gluten is a network of<br />
two protein types, glutenin and gliadin. In dry fl ours,<br />
these exist separately. Adding water makes these<br />
proteins form chemical links (disulphide bonds) with<br />
one another, and kneading or mixing forms even<br />
more bonds. These bonds make the resulting gluten<br />
network strong and elastic.<br />
Gluten can be found in foods containing wheat,<br />
barley and rye. This is a really broad category, and<br />
includes pasta, noodles, condiments, many prepackaged<br />
snacks, and beer.<br />
TO EAT OR NOT TO EAT?<br />
Coeliac disease?<br />
Coeliac disease is an autoimmune disease<br />
that presents as a response to the gliadin protein in<br />
gluten in the small intestine of a sensitive person.<br />
That is, the body of a coeliac sufferer mounts an<br />
immune response to the presence of gliadin in<br />
the small intestine, in the same way that it would<br />
initiate an immune response to fi ght off an infection.<br />
It produces antibodies that attack the gliadin<br />
molecule, an otherwise harmless protein.<br />
As a result, coeliacs suffer infl ammation<br />
and damage to the lining of the small intestine.<br />
Coeliac disease can be diagnosed by a doctor after<br />
a blood test to check for antibodies known as tissue<br />
transglutaminase antibodies (tTG-IgA), as well as a<br />
series of other tests for patients who may be at risk<br />
of returning a false positive on the tTG-IgA test (such<br />
as Type 1 diabetics and people with rheumatoid<br />
arthritis, both also autoimmune diseases). This is<br />
followed up by a biopsy to see if the lining of your<br />
small intestine is damaged.<br />
For coeliacs, gluten really is that bad, at any<br />
level. No cheat meals allowed here – even trace<br />
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