11-13 May 2012 Helsingør - Denmark www.networkbio.org
11-13 May 2012 Helsingør - Denmark www.networkbio.org
11-13 May 2012 Helsingør - Denmark www.networkbio.org
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Friday <strong>11</strong>th may <strong>2012</strong><br />
09:00 - 15:00 Registration Open<br />
Session I: KINOME BIOLOGY<br />
Chair: Blagoy Blagoev - University of Southern <strong>Denmark</strong> Session<br />
Programme<br />
15:00 Welcome by Rune Linding<br />
15:10 - 16:00 OPENING LETURE: Eng Lim Goh (SGI, USA) - New Developments in Computing for the Life<br />
Sciences Researcher<br />
16:00 - 16:30 Andrea Califano (Columbia University, New York NY) - Dissecting and interrogating signaling<br />
networks in human malignancies<br />
16:30 - 16:45 Coffee Break and Sponsor Exhibition<br />
16:45 - 17:15 Rune Linding (DTU, Lyngby DK) - Modeling Cancer Kinome Networks<br />
17:15 - 17:30 Gianni Cesareni (Tor Vergata, Rome, Italy) - Mapping the human phosphatome on growth<br />
pathways<br />
17:30 - 17:50 Sponsored Talk (SBV Improver) - Julia Hoeng – Verification of System Biology Research in<br />
the age of Collaborative Competition<br />
17:50 - 18:00 Break<br />
18:00 - 18:15 Sol Efroni (Bar Ilan University, Israel) - Network-based metrics reveals a novel role for<br />
hsa-miR-9 and drug control over the p38 network in glioblastoma multiforme progression<br />
18:15 - 18:45 Garry Nolan (Stanford, San Francisco CA)<br />
19:00 - Poster Session, Drinks and Welcome Dinner at Hotel<br />
Saturday 12th may <strong>2012</strong><br />
Session II: DISEASE NETWORKS<br />
Chair: Ramneek Gutpa - Technical Univeristy of <strong>Denmark</strong> Session<br />
09:10 - 10:00 KEYNOTE LECTURE: Norbert Perrimon (Harvard Medical School, Boston USA) - Building<br />
and validating signaling networks in Drosophila<br />
10:00 - 10:30 Dana Pe’er (Columbia,USA) - On the road to personalized therapy, a systems approach<br />
10:30 - <strong>11</strong>:00 Marc Vidal (DFCI, Boston USA) - Interactome Networks and Human Disease<br />
<strong>11</strong>:00 - <strong>11</strong>:30 Coffe Break and Sponsor Exhibition<br />
<strong>11</strong>:30 - <strong>11</strong>:45 Stephan M. Feller (Oxford, UK) - How are complex signal computations in cells accomplished<br />
by multiprotein complexes assembled on ‘intrinsically disordered’ platform proteins?<br />
The N-terminal folding nucleation (NFN)hypothesis<br />
12:45 -12:00 Theo Knijnenburg (NCI,Amsterdam, NL) - Drug sensitivity of cancer cell lines explained as a<br />
logic combination of mutations<br />
12:00 - 12:30 Søren Brunak (DTU, Lyngby DK) - Interfacing disease phenotypes from electronic patient<br />
records to the underlying network biology<br />
12:30 - <strong>13</strong>:30 Lunch with Sponsored Talk (Thermo Fisher) - Christian Kelstrup (NNF-CPR, Copenhagen,<br />
DK) Optimized Fast and Sensitive Acquisition Methods for Shotgun Proteomics on a Quadru<br />
pole Orbitrap Mass Spectrometer<br />
Programme<br />
Session III: NETWORK DRUGS<br />
Chair: Christopher Workman - Technical University of <strong>Denmark</strong><br />
<strong>13</strong>:30 - 14:20 KEYNOTE LECTURE: Michael Yaffe (MIT, Cambridge USA)<br />
14:20 - 14:50 Matt Onsum (Merrimack Pharmaceuticals, USA) - Using systems biology to accelerate onco<br />
logy drug development<br />
14:50 - 15:15 Coffee Break and Sponsor Exhibition<br />
15:15 - 15:30 Ruth Hüttenhain (ETH Zurich, CH) - A mass spectrometric map for reproducible quantification<br />
of cancer associated proteins in body fluids<br />
15:30 - 16:00 Janine Erler (BRIC, Copenhagen DK) - Molecular networks associated with<br />
cancer progression<br />
16:00 - 16:30 Nevan Krogan (UCFS, San Francisco USA) - Functional Insights from Protein-<br />
Protein and Genetic Interaction Maps<br />
16:30 - 18:30 Poster Session and Sponsor Exhibition<br />
19:00 Transfer to Louisiana Museum for Gala Dinner<br />
20:00 Welcome Speech by SGI<br />
23:00 Buses back to Hotels<br />
Sunday <strong>13</strong>th may <strong>2012</strong><br />
Session IV: INTEGRATIVE NETWORK BIOLOGY<br />
Chair: tba<br />
09:00 -09:50 KEYNOTE LECTURE: Ruedi Aebersold (ETH, Switzerland) - Network Driven Protein Biomar<br />
ker Discovery and Validation<br />
09:50 - 10:20 Anne Claude Gavin (EMBL, Heidelberg DE) - Expanding the interaction space;<br />
protein-metabolite networks<br />
10:20 - 10:45 Coffee Break and Sponsor Exhibition<br />
10:45 - <strong>11</strong>:00 Ulrich Stelzl (MPI Molecular Genetics, Berlin, Germany) A Y2H-seq approach to define the<br />
protein ethyltransferase interactome<br />
<strong>11</strong>:00 - <strong>11</strong>:30 Marian Walhout (UMASS-MED, Worcester MA) - Gene regulatory networks<br />
<strong>11</strong>:30 - 12:00 Ben Lehner (CRG, Barcelona, Spain) - The biology of individuals<br />
12:00 - 12:30 Bernhard Pallson (DTU/UCSD, Lyngby, DK / San Diego, CA) - Systems Biology of<br />
Metabolism<br />
2 / INB <strong>2012</strong> • <strong>11</strong>-<strong>13</strong> <strong>May</strong> <strong>2012</strong> <strong>www</strong>.<strong>networkbio</strong>.<strong>org</strong> / 3