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11-13 May 2012 Helsingør - Denmark www.networkbio.org

11-13 May 2012 Helsingør - Denmark www.networkbio.org

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Friday <strong>11</strong>th may <strong>2012</strong><br />

09:00 - 15:00 Registration Open<br />

Session I: KINOME BIOLOGY<br />

Chair: Blagoy Blagoev - University of Southern <strong>Denmark</strong> Session<br />

Programme<br />

15:00 Welcome by Rune Linding<br />

15:10 - 16:00 OPENING LETURE: Eng Lim Goh (SGI, USA) - New Developments in Computing for the Life<br />

Sciences Researcher<br />

16:00 - 16:30 Andrea Califano (Columbia University, New York NY) - Dissecting and interrogating signaling<br />

networks in human malignancies<br />

16:30 - 16:45 Coffee Break and Sponsor Exhibition<br />

16:45 - 17:15 Rune Linding (DTU, Lyngby DK) - Modeling Cancer Kinome Networks<br />

17:15 - 17:30 Gianni Cesareni (Tor Vergata, Rome, Italy) - Mapping the human phosphatome on growth<br />

pathways<br />

17:30 - 17:50 Sponsored Talk (SBV Improver) - Julia Hoeng – Verification of System Biology Research in<br />

the age of Collaborative Competition<br />

17:50 - 18:00 Break<br />

18:00 - 18:15 Sol Efroni (Bar Ilan University, Israel) - Network-based metrics reveals a novel role for<br />

hsa-miR-9 and drug control over the p38 network in glioblastoma multiforme progression<br />

18:15 - 18:45 Garry Nolan (Stanford, San Francisco CA)<br />

19:00 - Poster Session, Drinks and Welcome Dinner at Hotel<br />

Saturday 12th may <strong>2012</strong><br />

Session II: DISEASE NETWORKS<br />

Chair: Ramneek Gutpa - Technical Univeristy of <strong>Denmark</strong> Session<br />

09:10 - 10:00 KEYNOTE LECTURE: Norbert Perrimon (Harvard Medical School, Boston USA) - Building<br />

and validating signaling networks in Drosophila<br />

10:00 - 10:30 Dana Pe’er (Columbia,USA) - On the road to personalized therapy, a systems approach<br />

10:30 - <strong>11</strong>:00 Marc Vidal (DFCI, Boston USA) - Interactome Networks and Human Disease<br />

<strong>11</strong>:00 - <strong>11</strong>:30 Coffe Break and Sponsor Exhibition<br />

<strong>11</strong>:30 - <strong>11</strong>:45 Stephan M. Feller (Oxford, UK) - How are complex signal computations in cells accomplished<br />

by multiprotein complexes assembled on ‘intrinsically disordered’ platform proteins?<br />

The N-terminal folding nucleation (NFN)hypothesis<br />

12:45 -12:00 Theo Knijnenburg (NCI,Amsterdam, NL) - Drug sensitivity of cancer cell lines explained as a<br />

logic combination of mutations<br />

12:00 - 12:30 Søren Brunak (DTU, Lyngby DK) - Interfacing disease phenotypes from electronic patient<br />

records to the underlying network biology<br />

12:30 - <strong>13</strong>:30 Lunch with Sponsored Talk (Thermo Fisher) - Christian Kelstrup (NNF-CPR, Copenhagen,<br />

DK) Optimized Fast and Sensitive Acquisition Methods for Shotgun Proteomics on a Quadru<br />

pole Orbitrap Mass Spectrometer<br />

Programme<br />

Session III: NETWORK DRUGS<br />

Chair: Christopher Workman - Technical University of <strong>Denmark</strong><br />

<strong>13</strong>:30 - 14:20 KEYNOTE LECTURE: Michael Yaffe (MIT, Cambridge USA)<br />

14:20 - 14:50 Matt Onsum (Merrimack Pharmaceuticals, USA) - Using systems biology to accelerate onco<br />

logy drug development<br />

14:50 - 15:15 Coffee Break and Sponsor Exhibition<br />

15:15 - 15:30 Ruth Hüttenhain (ETH Zurich, CH) - A mass spectrometric map for reproducible quantification<br />

of cancer associated proteins in body fluids<br />

15:30 - 16:00 Janine Erler (BRIC, Copenhagen DK) - Molecular networks associated with<br />

cancer progression<br />

16:00 - 16:30 Nevan Krogan (UCFS, San Francisco USA) - Functional Insights from Protein-<br />

Protein and Genetic Interaction Maps<br />

16:30 - 18:30 Poster Session and Sponsor Exhibition<br />

19:00 Transfer to Louisiana Museum for Gala Dinner<br />

20:00 Welcome Speech by SGI<br />

23:00 Buses back to Hotels<br />

Sunday <strong>13</strong>th may <strong>2012</strong><br />

Session IV: INTEGRATIVE NETWORK BIOLOGY<br />

Chair: tba<br />

09:00 -09:50 KEYNOTE LECTURE: Ruedi Aebersold (ETH, Switzerland) - Network Driven Protein Biomar<br />

ker Discovery and Validation<br />

09:50 - 10:20 Anne Claude Gavin (EMBL, Heidelberg DE) - Expanding the interaction space;<br />

protein-metabolite networks<br />

10:20 - 10:45 Coffee Break and Sponsor Exhibition<br />

10:45 - <strong>11</strong>:00 Ulrich Stelzl (MPI Molecular Genetics, Berlin, Germany) A Y2H-seq approach to define the<br />

protein ethyltransferase interactome<br />

<strong>11</strong>:00 - <strong>11</strong>:30 Marian Walhout (UMASS-MED, Worcester MA) - Gene regulatory networks<br />

<strong>11</strong>:30 - 12:00 Ben Lehner (CRG, Barcelona, Spain) - The biology of individuals<br />

12:00 - 12:30 Bernhard Pallson (DTU/UCSD, Lyngby, DK / San Diego, CA) - Systems Biology of<br />

Metabolism<br />

2 / INB <strong>2012</strong> • <strong>11</strong>-<strong>13</strong> <strong>May</strong> <strong>2012</strong> <strong>www</strong>.<strong>networkbio</strong>.<strong>org</strong> / 3

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