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Topical treatments for fungal infections of the skin and nails of the foot.

Topical treatments for fungal infections of the skin and nails of the foot.

Topical treatments for fungal infections of the skin and nails of the foot.

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Carter 1972<br />

Methods RCT<br />

Study aim clearly defined: yes<br />

Blinded assessor <strong>of</strong> primary outcome: yes<br />

Double blind study: yes<br />

Participants comparable at baseline <strong>for</strong> age: not stated Sex: not stated Duration <strong>of</strong> complaint: not stated<br />

Inclusion <strong>and</strong> exclusion criteria specified: yes<br />

Interventions well described: yes<br />

Assessment <strong>of</strong> compliance: not stated<br />

Intention to treat analysis: not stated<br />

A Priori sample size calculation: not stated<br />

Fungi identified: yes<br />

Distribution <strong>of</strong> species between groups: not given<br />

Adverse events reported: yes<br />

Number <strong>of</strong> drop outs stated: no<br />

Participants Total evaluable sample size: 81<br />

Exclusion criteria: any <strong>the</strong>rapeutic or prophylactic medication taken within three weeks prior to study<br />

Treatment setting: prison<br />

Interventions a. Haloprogin 1% foam, solution or cream<br />

Duration: four weeks<br />

Frequency: applied twice daily<br />

b. Tolnaftate 1% solution<br />

Duration: four weeks<br />

Frequency: applied twice daily<br />

Outcomes Primary outcome: cure<br />

Secondary Outcomes: lesion scores<br />

Adverse events: none in ei<strong>the</strong>r group<br />

Notes<br />

Risk <strong>of</strong> bias<br />

Item Authors’ judgement Description<br />

Allocation concealment? Unclear B - Unclear<br />

<strong>Topical</strong> <strong>treatments</strong> <strong>for</strong> <strong>fungal</strong> <strong>infections</strong> <strong>of</strong> <strong>the</strong> <strong>skin</strong> <strong>and</strong> <strong>nails</strong> <strong>of</strong> <strong>the</strong> <strong>foot</strong>. (Review)<br />

Copyright © 2009 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.<br />

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