The Prediction of Chromosomal Effects and Their ... - Lhasa Limited
The Prediction of Chromosomal Effects and Their ... - Lhasa Limited
The Prediction of Chromosomal Effects and Their ... - Lhasa Limited
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Results <strong>of</strong> toxicophore development<br />
• To date, 50 <strong>of</strong> the 103 toxicophores have been<br />
investigated<br />
• Currently the Derek for Windows knowledge<br />
base contains 63 alerts for chromosome damage<br />
• From this work, several common mechanisms<br />
for the induction <strong>of</strong> chromosomal effects that do<br />
not involve direct damage to DNA have become<br />
apparent
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