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Elisa Encarnacion "Caracterización del veneno del alacrán Hadruroides lunatus" Gerardo Pavel Espino "Desarrollo de anticuerpos contra integrinas de células dendríticas de caballo con miras a su aplicación biotecnológica" Georgina Estrada "Obtencion de toxinas recombinantes ricas en puentes disulfuro para estudios de estructura y funcion" Juana Jimenez "Expresión heteróloga de genes que codifican para toxinas de alacranes" Rita Restano "Estudios electrofisiológicos de las toxinas del veneno de alacranes" Publicaciones recientes Aguilar,M.B. Lopez-Vera,E. Ortiz,E. Becerril,B. Possani,L.D. Olivera,B.M. Heimer de la Cotera EP 2005. A Novel Conotoxin from Conus delessertii with Posttranslationally Modified Lysine Residues Biochemistry 44 11130-11136. Coronas,F.I. Balderas,C. Lopez,L.P. Possani,L.D. Gurrola,G.B. 2005. Amino acid sequence determination and chemical synthesis of CllErg1 (gamma-KTx1.5), a K+ channel blocker peptide isolated from the scorpion Centruroides limpidus limpidus Journal of the Brazilian Chemical Society 16 404-411. Olamendi-Portugal,T. Somodi,S. Fernandez,J.A. Zamudio,F.Z. Becerril,B. Varga,Z. Panyi,G. Gaspar,R. Possani,L.D. 2005. Novel alpha-KTx peptides from the venom of the scorpion Centruroides elegans selectively blockage Kv1.3 over IKCa1 K(+) channels of T cells Toxicon 46 418-429 [Epub July]. Padilla,A. Govezensky,T. Possani,L.D. Larralde,C. 2005. Mortality and antibody responses of mice to three successive episodes of experimental scorpion (Centruroides limpidus limpidus) envenomation and immunological rescue Toxicon 46 142-149 [Epub June 2005]. Rodriguez de la Vega RC Possani,L.D. 2005. On the evolution of invertebrate defensins Trends Genet. 21 330-332. Riano-Umbarila,L. Juarez-Gonzalez,V.R. Olamendi-Portugal,T. Ortiz-Leon,M. Possani,L.D. Becerril,B. 2005. A strategy for the generation of specific human antibodies by directed evolution and phage display FEBS J 272 2591-2601. Gazarian,K.G. Gazarian,T. Hernandez,R. Possani,L.D. 2005. Immunology of scorpion toxins and perspectives for generation of anti-venom vaccines Vaccine 23 3357-3368.
Juarez-Gonzalez,V.R. Riano-Umbarila,L. Quintero-Hernandez,V. Olamendi-Portugal,T. Ortiz-Leon,M. Ortiz,E. Possani,L.D. Becerril,B. 2005. Directed Evolution, Phage Display and Combination of Evolved Mutants: A Strategy to Recover the Neutralization Properties of the scFv Version of BCF2 a Neutralizing Monoclonal Antibody Specific to Scorpion Toxin Cn2 J Mol Biol 346 1287-1297. Diego-Garcia,E. Batista,C.V. Garcia-Gomez,B.I. Lucas,S. Candido,D.M. Gomez-Lagunas,F. Possani,L.D. 2005. The Brazilian scorpion Tityus costatus Karsch: genes, peptides and function Toxicon 45 273-283. Bagdaany,M. Batista,C.V. Valdez-Cruz,N.A. Somodi,S. Rodriguez de la Vega RC Licea,A.F. Varga,Z. Gaspar,R. Possani,L.D. Panyi,G. 2005. Anuroctoxin, a new scorpion toxin of the {alpha}-KTx 6 subfamily is highly selective for Kv1.3 over IKCa1 ion channels of human T lymphocytes Mol Pharmacol. 67 1034- 1044 [Epub 2004 Dec]. Valdez-Cruz,N.A. Batista,C.V. Zamudio,F.Z. Bosmans,F. Tytgat,J. Possani,L.D. 2004. Phaiodotoxin, a novel structural class of insect-toxin isolated from the venom of the Mexican scorpion Anuroctonus phaiodactylus Eur.J Biochem 271 4753-4761. D'Suze,G. Batista,C.V. Frau,A. Murgia,A.R. Zamudio,F.Z. Sevcik,C. Possani,L.D. Prestipino,G. 2004. Discrepin, a new peptide of the sub-family alpha-ktx15, isolated from the scorpion Tityus discrepans irreversibly blocks K(+)-channels (I(A) currents) of cerebellum granular cells Arch.Biochem Biophys. 430 256-263. Valdez-Cruz,N.A. Davila,S. Licea,A. Corona,M. Zamudio,F.Z. Garcia-Valdes,J. Boyer,L. Possani,L.D. 2004. Biochemical, genetic and physiological characterization of venom components from two species of scorpions: Centruroides exilicauda Wood and Centruroides sculpturatus Ewing Biochimie 86 387-396. Frenal,K. Xu,C.Q. Wolff,N. Wecker,K. Gurrola,G.B. Zhu,S.Y. Chi,C.W. Possani,L.D. Tytgat,J. Delepierre, M. 2004. Exploring structural features of the interaction between the scorpion toxinCnErg1 and ERG K(+) channels Proteins 56 367-375. Rodriguez-de-la-Vega,R. Possani,L.D. 2004. Current views on scorpion toxins specific for K(+)-channels Toxicon 43 865-875. Rodriguez-de-la-Vega,R. Garcia,B. D'Ambrosio,C. Diego-Garcia,E. Scaloni,A. Possani,L.D. 2004. Antimicrobial peptide induction in the haemolymph of the Mexican scorpion Centruroides limpidus limpidus in response to septic injury Cell Mol Life Sci 61 1507-1519. Rio-Portilla,F. Hernandez-Marin,E. Pimienta,G. Coronas,F.V. Zamudio,F.Z. Rodriguez-de-la-Vega,R. Wanke,E. Possani,L.D. 2004. NMR solution structure of Cn12, a novel peptide from the Mexican scorpion Centruroides noxius with a typical beta-toxin sequence but with alpha-like physiological activity Eur.J
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Informe de actividades 2004 Ayuda U
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Ayuda Instituto de Biotecnología U
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Instituto de Biotecnología UNAM In
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Molecular Dr. Omar H. Pantoja Ayala
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Adriana Luna Publicaciones reciente
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Gaytán R, Sánchez-Flores F, Moral
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Flores,G. Soberon,X. Osuna,J. 2004.
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Yáñez J, Argüello M, Osuna J, So
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X. Soberón P.Gaitán 2003 Fmoc-tri
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la coocurrencia y anticorrelación
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products resulting from DNA shuffli
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identificación de vías metabólic
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modulación de las vías de transfe
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manganese: evidence of a protein ce
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Dayanira Sheira Estudiante Jorge Al
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Vazquez-Duhalt,R. Ayala,M. Marquez-
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Líneas de Investigación: Ingenier
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Drosophila acetylcholinesterase sub
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Palomares,L.A. Pedroza,J.C. Ramirez
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Meneses-Acosta,A. Mendonca,R. Merch
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troncales representan una fuente im
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Minerva Carcano Administrativo Miri
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Monyer H, Sprengel R, Schoepfer R,
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Adriana Dinora Rios Jorge Villoria
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Felix,R. Sandoval,A. Sanchez,D. Gom
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mammalian spermatogenic cells FEBS
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entrada de Ca2+ activada por sperac
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por: PKA, pHi, [Ca2+]i e hiperpolar
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sperm acrosome reaction. Dev Biol,
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Pablo Martinez Instituto de Biotecn
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Darszon,A. Wood,C.D. Beltran,C. San
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Nishigaki,T. Wood,C.D. Tatsu,Y. Yum
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87-92. Felix,R. Sandoval,A. Sanchez
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channels Biochem Biophys.Res Commun
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Gerardo Escalera Estudiante Ana Lau
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Publicaciones recientes Gasque,G. L
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Reynaud E, Vázquez M, Zurita M . 1
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Publicaciones recientes Gutierrez,L
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Corona,M. Gurrola,G.B. Merino,E. Ca
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conjunto de mas de 4,000 familias d
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Bioinformática Biología Molecular
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Perez-Rueda,E. Collado-Vides,J. 200
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están relacionadas las proteínas
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transpeptidase fold. Prot Eng, 16 ,
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Viviana Escobar "EXPLORACION DEL ES
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Specificity: Two Structural Determi
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facilitates proteolytic cleavage of
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Specificity: Two Structural Determi
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Juan Conde Lili Esmeralda Gallo Nur
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complementarity determines interact
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Vázquez-Padrón RI, de la Riva G,
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Rausell,C. Munoz-Garay,C. Miranda-C
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mechanism of action of the B. thuri
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Miranda,R. Zamudio,F.Z. Bravo,A. 20
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Cn2 and the Neutralizing Monoclonal
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capacidad de deformar los pelos rad
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COMPUESTOS NITROGENADOS EN EL NODUL
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transportador HAK5 en el tonoplasto
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plasma membrane of Arabidopsis Plan
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Mandel A, Feldmann K, Herrera-Estre
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Ma. Elena Cortes "CARACTERIzACION D
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Fuentes de financiamiento: CONACyT
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Lopez,T. Camacho,M. Zayas,M. Najera
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Arias,C.F. Dector,M.A. Segovia,L. L
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secuencial por el virus durante su
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Dr. Ernesto Mendez Investigador Tut
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Liliana Maruri "El Papel de las cha
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Esquivel,F.R. Lopez,S. Guitierrez,X
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Hector Eugenio Sanchez . Administra
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of rotavirus gene expression Virus
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Zarate,S. Espinosa,R. Romero,P. Men
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secuencial por el virus durante su
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Q.F.B. Rafaela Espinosa Tutor de Ma
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Camilo Ayala "Estudio de la cinéti
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Arias,C.F. 2002. Heat shock cognate
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on the transcriptional activator Ph
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Biotechnol 29 209-213. Peralta-Gil,
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Biología Molecular y Bioquimica de
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Publicaciones recientes Fernandez-M
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organismos. El análisis de la regu
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Dr. Victor Humberto Bustamante Tuto
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Karol Carrillo "Caracterización mo
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Finlay, B. B., J. L. Puente , W. De
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malate synthase Can.J Microbiol 48
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Medina,G. Juarez,K. Soberon-Chavez,
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Marcelo Espin Estudiante Estefania
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Premio Universidad Nacional en el
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obtain marker-free chromosomal inse
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Escalante-Lozada,A. Gosset-Lagarda,
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mostraron menos del 95% de similitu
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Ingeniería y Tecnología de las Fe
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Publicaciones recientes Flores,N. d
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las células blanco. La eficiencia
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Manuel Villa Administrativo Institu
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Alonso Martinez Edna Matta Alejandr
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Jorge Lozada Instituto de Biotecnol
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vías de señalización intracelula
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Tuberculosis and in Tuberculosis Pa
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immunomodulatory drug leflunomide J
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Cote-Velez,A. Perez-Martinez,L. Dia
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del TRH, la PPII, así como en los
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Elizabeth Ramirez Estudiante Daniel
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Nashiely Yanez Publicaciones recien
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activity in the anterior pituitary
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Exposure or Suckling Indicate Funct
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Premio Image-Pro In Action 3er luga
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assessment of Trichoderma harzianum
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Boris Jimenez Jose Luis Lopez "Estu
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Publicaciones recientes Shishkova,S
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en el meristemo es un componente pr
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protein 101 gene, HSP101, encoding
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diversity: Microbial culture-indepe
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oth as a function of mycelial morph
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mostraron menos del 95% de similitu
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cyclomaltodextrin glucanotransferas
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la coocurrencia y anticorrelación
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products resulting from DNA shuffli
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asas de ocho barriles seleccionados
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petroporphyrins by chemical modifie
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3. Aislamiento y caracterización d
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protein 101 gene, HSP101, encoding
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transportador HAK5 en el tonoplasto
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encoding tubulin in Drosophila mela
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glucose and glutamine in the metabo
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uso de compuestos enjaulados, nueva
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del TRH, la PPII, así como en los
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Elizabeth Ramirez Estudiante Daniel
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caracterización de una colección
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conjunto de mas de 4,000 familias d
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organismos. El análisis de la regu
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estudiando los mecanismos molecular
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los compartimentos definidos por lo
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Tityus cambridgei y Tityus costatus
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scorpion toxins that specifically i
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Linda Espinosa Administrativo Insti
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procariotes y de células de eucari
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Sánchez R, Alagón A, Stock R . 20
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Maria Xochitl Gonzalez Administrati
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Lopez, S. Arias, C.F. 2004. Preface
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● Transducción de señales en Rh
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Rodriguez-de-la-Vega, R. Possani, L
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Año Instituto de Biotecnología UN
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National Research Counsil. Canadá
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1997 E. Galindo F. M. E. Ramírez G
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determinación de dióxido de cloro
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1997 E. Galindo F. M. E. Ramírez G
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Caracterización bioquímica y func
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Comparación inmunoquímica del ven
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Modificación química de la clorop
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Control transcripcional del operón
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Estudio de la biosíntesis de la TR
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Dr. Jorge Méndez, Dirección de Ve
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Rafael Vázquez-Duhalt (Miembro del
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Profr.María de los Angeles Chávez
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IBt., Cuernavaca, Morelos, México
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2004 - Instituto de Biotecnología - UNAM

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