dihibriduli Sejvareba

1.12 pleiotropia
wina gakveTilebze ganxiluli magaliTebidan Cans, rom zogierTi niSan-Tvisebis
gamovlena ramdenime genis urTierTqmedebis Sedegia. arsebobs sapirispiro movlenac,
rodesac zogierTi geni ori an ramdenime niSan-Tvisebis ganviTarebaze axdens gavlenas.
am movlenas pleiotropia (berZn. `pleion~ _ mravlobiTi, `tropos~ _ mimarTuleba), anu
genis mravlobiTi moqmedeba, ewodeba, xolo genebs, romelTac mravali gansxvavebuli
efeqti aqvT _ pleiotropiuli genebi.
mravlobiTi, anu pleiotropiuli, moqmedebis pirvel magaliTs TviT
mendelis naSromSi vxvdebiT. man aRwera, rom im wiTelyvavila mcenareebs,
romelTac foTlis iRliebSic wiTeli laqebi hqondaT, yovel-
Tvis aReniSnebodaT Teslis kanis ruxi Seferiloba da ivarauda, rom am
niSnebis damemkvidreba erTi memkvidruli faqtoriT ganisazRvreba.
genebis pleiotropiuli moqmedeba gamovlenilia adamianebsur.1.
faraoni
Sic. cnobilia dominanturi geni, romelic sayrden-mamoZravebeli
sistemis damaxasiaTebel cvlilebebTan erTad (dagrZelebuli Zvlebi,
zedmetad moZravi saxsrebi) Tvalis brolis anomaliebs da gulis
manksac gansazRvravs. am daavadebis niSnebi pirvelad frangma eqimma
exnatoni
a. marfanma aRwera 1896 wels. amitom mas
marfanis sindromi uwodes.
varaudoben, rom marfanis sindromiT iyvnen
daavadebuli faraoni exnatoni (sur. 1), genialuri
mevioline nikolo paganini, hans qristian
anderseni, abraam linkolni da sxva cnobili
adamianebi. amis gamo marfanis sindroms
sur.3.
zogjer geniosebis sindromsac uwodeben.
daakvirdiT suraTze biWis (sur. 2) xe-
sur.2.
lis mtevnebs da rentgenogramas (sur. 3). aseTi zedmetad
grZeli TiTebi marfanis sindromis erT-erTi simptomia da
mas `obobas TiTebs~ an araqnodaqtilias (berZn. `araqne~
_ oboba, `daqtilos~ _ TiTi)
uwodeben.
albaT, gagiWirdebaT, xelis
mtevnebs iseTi forma misceT,
rogoric am suraTebzea (sur.
4) gamosaxuli. amgvari zedmetad
moqnili saxsrebic marfanis sindromisTvis aris damaxasiaTebeli.
sur.4.
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