dihibriduli Sejvareba
dihibriduli Sejvareba
dihibriduli Sejvareba
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genomuri daqtiloskopia swored nukleotid-<br />
Ta gansxvavebuli jgufebis _ variabeluri ubnebis<br />
gamovlenas gulisxmobs. amisaTvis pirvel<br />
rigSi unda moxdes dnm-s gamoyofa adamianis<br />
ujredebidan da Semdeg misi dayofa fragmentebad.<br />
rogorc iciT, baqteriebidan gamoyofil<br />
fermentebs _ restriqtazebs aqvT unari, dnm-s<br />
molekulebi mcire zomis fragmen tebad daWran. sur. 4. gel-eleqtroforezis Sedegad miRebuli<br />
dnm-s fragmentebis suraTi<br />
amis Semdeg specialuri bioqimiuri meTodiT _<br />
gel-eleqtroforeziT xdeba am fragmentebis gancalkeveba maTi<br />
zomebis mixedviT. suraTze (sur.4.) mocemulia 6 adamianis dnm-s<br />
fragmentebi, romlebic variabelur ubnebs Seicavs.<br />
genomuri daqtiloskopiis meTodi daamuSava ingliselma mecnierma<br />
alek jefrisma (sur.5). 1987 wels inglisis policiam pirvelad<br />
gamoiyena es meTodi damnaSavis gamosavlenad. amisaTvis 4500 adamians<br />
Cautarda genomuri analizi da dadginda mkvlelis vinaoba,<br />
romelmac ori gogonas sicocxle imsxverpla.<br />
amJamad es meTodi farTod gamoiyeneba sasamarTlo eqsper-<br />
sur. 5. alek jefrisi tizaSi ara marto damnaSaveTa gamosavlenad, aramed adamianTa Soris<br />
naTesauri kavSirebis (mag., mamobis) dasadgenad.<br />
• moifiqreT, rogor adgenen mamobas genomuri daqtiloskopiis gamoyenebiT.<br />
genomuri daqtiloskopiis Teoriuli da gamoyenebiTi problemebis<br />
gadaWraSi did wvlili miuZRvis qarTvel mecniers apolon jin-<br />
WaraZes (sur.6.). man daamuSava individTa identificirebis meTodebi<br />
mcenareebis, cxovelebisa da mikroorganizmebisaTvis da misi eqsperimentebis<br />
Sedegad genomuri daqtiloskopiis meTodma universaluri<br />
saxe miiRo. apolon jinWaraZe moulodnelad gardaicvala<br />
25 wlis asakSi. mas sikvdilis Semdeg mieniWa ruseTis federaciis<br />
saxelmwifo premia. unda aRiniSnos, rom aseTi premia qarTvel mecnierTagan<br />
mxolod ivane beritaSvils xvda wilad.<br />
gel-eleqtroforeziT dnm-s fragmentebis da- sur. 6.<br />
apolon jinWaraZe<br />
calkeveba dnm-s sakmaod mniSvnelovan raodenobas<br />
moiTxovs. magram zogjer saWiroa pirovnebis identificireba misi sul<br />
ramdenime ujredis an gaxrwnili gvamis ukve daSlili qsovilebis mixedviT.<br />
cxadia, aseT SemTxvevaSi ujredebidan gamoyofili dnm analizis<br />
Casatareblad sakmarisi ar iqneba. am problemis gadasaWrelad dRes<br />
warmatebiT iyeneben polimerazuli jaWvuri reaqciis (PCR – Polymeraze<br />
Chain Reaction) meTods (pjr-s). meTodi daamuSava amerikelma mecnierma<br />
keri mulisma (sur.7.), risTvisac mas nobelis premia mieniWa.<br />
sur. 7. keri mulisi<br />
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