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Scarica la Relazione - Fondazione Disturbi del Sonno

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CAP rate was decreased in all<br />

NREM sleep stages (in<br />

particu<strong>la</strong>r CAP A1 subtypes) in<br />

narcoleptic patients who also<br />

showed significant higher<br />

values of all types of LMs.<br />

Sleep microstructure and LM<br />

activity changes observed in<br />

adulthood are already present<br />

and detectable in childhood and<br />

might have a role in the already<br />

known impaired prefrontal<br />

functioning of these subjects.<br />

The well-established orexin<br />

deficiency might be the unifying<br />

factor.

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