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Anabolic resistance: a road map to malnutrition

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PREOPERATIVE INSULIN RESISTANCE AND THE IMPACT OF FEEDING ON POSTOPERATIVE<br />

Delta in phenylalanine protein balance<br />

(micromo/kg/min) expressed expressed as<br />

differences fed values minus fast<br />

7<br />

6<br />

5<br />

4<br />

3<br />

PROTEIN BALANCE. A STABLE ISOTOPE STUDY<br />

Francesco Donatelli, Davide Corbella, Marta Di Nicola, Franco Carli, Luca Lorini, Rober<strong>to</strong> Fumagalli, Gianni Biolo.<br />

Ospedali Riuniti di Bergamo, Italy; McGill University Health Centre, Montreal, Quebec, Canada; University of Trieste, Italy<br />

J Clin Endocrinol Metab 2011<br />

2<br />

1<br />

0<br />

ANABOLIC EFFICIENCY OF FEEDING<br />

Normal insulin<br />

sensititivity<br />

Preoperative insulin<br />

<strong>resistance</strong><br />

PRE-SURGERY POST-SURGERY<br />

Well-nourished patients with coronary artery disease<br />

Elective coronary by-pass surgery<br />

*, p=0.04, surgery effect of; p=0.002, group effect; p

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