Anabolic resistance: a road map to malnutrition

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Inactivity Amplifies the Catabolic Response of Skeletal Muscle to Cortisol Ferrando et al., J Clin Endocrinol & Metab, 1999 Ambulatory 5-days nmol phenylalanine/ /min/100 ml leg vol. 12-h hydrocortisone infusion (120 microg/kg/h) 0 -25 -50 -75 Bed rest 14-days MUSCLE PROTEIN BALANCE P
percent 50 25 0 Meal-induced stimulation of protein synthesis * * AMB BR AMB BR Eucaloric diet Hypocaloric diet micromol leucine/kh/min kg 0.30 0.25 0.20 0.15 0.2 -0.2 -0.6 -1 -1.4 CHANGES IN LEAN MASS (DEXA) Eucaloric Ambulatory Hypocaloric Ambulatory Eucaloric Hypocaloric Bed Rest Bed Rest Protein catabolism in the fasting state AMB BR AMB BR Eucaloric diet Hypocaloric diet * *
Page 1 and 2: The Danish Society of Clinical Nutr
Page 3: EFFECTS OF AMINO ACID INFUSION ON S
Page 6 and 7: F M,A / F IN F V,A MODEL OF LEG MUS
Page 8 and 9: J. Clin. Invest. 95:811-819, 1995 M
Page 10 and 11: MUSCLE PROTEIN SYNTHESIS ml/min/100
Page 12 and 13: Am J Physiol. 1995 Mar;268(3 Pt 1):
Page 14 and 15: nmol PHE/min x 100 ml leg vol. Regu
Page 16: EXERCISE INACTIVITY ? INCREASED ANA
Page 19 and 20: Metabolic Effects of Very Low Calor
Page 21 and 22: MUSCLE MASS NORMAL NUTRITIONAL STAT
Page 23: AGING HORMONE DEFICIENCY OR EXCESS
Page 27 and 28: percent 40 30 20 10 0 PREVALENCE OF
Page 29 and 30: ∆ (kg) 2 Changes in fat mass (bio
Page 31 and 32: ∆ (kg) Changes in fat mass (bioim
Page 33 and 34: 2115 cancer patients 15% obesity 15
Page 36 and 37: Percent loss of lean body mass Long
Page 38: The majority of sick elderly patien
Page 41 and 42: Whole-body Whole-body Whole-body pr
Page 43: Medications and nutraceuticals to c
Page 46 and 47: 90-day strength training increased
Page 48: iolo@units.it Department of Interna

Anabolic resistance: a road map to malnutrition

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