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PDF File - Asclepius Herbal Consultancy

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Appendix VI<br />

Afferent CV<br />

Feedback<br />

↓ Activity<br />

Tractus Solitarius (TS)<br />

Inhibitory effect<br />

Baro- and<br />

Chemoreceptors<br />

Afferent Cardiovascular<br />

Feedback Activity<br />

Thalamus,<br />

Hypothalamus & Cortex<br />

Stress/Anxiety Activity<br />

Neurological<br />

Activation<br />

Amygdalioid Nucleus<br />

CRF Activity<br />

Locus Coeruleus (LC)<br />

Potentiation of<br />

Norepinephrine<br />

Dorsal Motor Vagus<br />

Nucleus<br />

(Parasympathetic)<br />

Activity<br />

Vagal preganglionic<br />

neurones<br />

Inhibitory effect<br />

Vagus Motor<br />

Innervation<br />

↓ Efferent<br />

Activity<br />

Endogenous CRF<br />

production<br />

Fig. 4: Corticotropin Releasing Factor Interactions<br />

Neurological<br />

Activation<br />

Norepinephrine<br />

Activity<br />

To the Heart of the Matter<br />

Vasomotor Regions in<br />

the Brain<br />

(Sympathetic)<br />

Activity<br />

Iintermediolateral<br />

columns of the spinal<br />

cord<br />

Inhibitory effect<br />

Vasomotor<br />

Innervation<br />

↓ Efferent<br />

Activity<br />

References: Guyton (1986), Berne et al. (1998) & Paulson et al. (1996),<br />

Thase & Howland (1995), Musselmann et al. (1998)<br />

58

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