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Millistak+HC AppGd_textC.qxd - Millipore

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Why Are Millistak+ HC<br />

Filters Better?<br />

Biological solids exhibit poor filter<br />

cake properties—very thin deposits<br />

exhibit very high flow resistance.<br />

The capacity of a clarifying depth<br />

filter is, therefore, highly dependent<br />

on the accessible internal surface<br />

area available for particle deposition.<br />

For a given media type and grade,<br />

capacity increases linearly with<br />

thickness or bed depth. Moreover,<br />

as commonly occurs in biological<br />

suspensions, the particles span a<br />

broad range of sizes—to maximize<br />

capacity, the filter media must be<br />

structured to accommodate these<br />

particle sizes in proportion to their<br />

number. For this reason, a gradient<br />

pore structure or media density<br />

is optimal.<br />

Outperforms the Competition<br />

Based on these design criteria,<br />

Millistak+ HC filters have been<br />

developed to outperform all competitive<br />

depth filters. Each cellulosic<br />

pad within the multilayer composite<br />

possesses a graded pore structure<br />

from front to back. Coupling two<br />

such pads in series expands the<br />

effective pore size range by as<br />

much as several orders of magnitude.<br />

In addition, Millistak+ HC filters<br />

employ two full-thickness cellulosic<br />

pads for an overall bed depth of more<br />

than 0.260 in.—thicker than any<br />

other cellulosic depth filter on the<br />

market today.<br />

Unique Membrane Layer<br />

Improves Performance<br />

A major advance in the design of<br />

stacked-disk prefilters, as offered in<br />

Millistak+ HC filters, is the incorporation<br />

of a microporous membrane layer,<br />

downstream of the cellulosic pads.<br />

The membrane layer delivers two<br />

important advantages. First, it serves<br />

as a final barrier to trap small particles<br />

and colloids that would otherwise<br />

foul a trailing sterile filter. Secondly,<br />

the membrane contributes a modest<br />

hydraulic resistance to the filter,<br />

which significantly improves feed<br />

flow distribution and, consequently,<br />

media utilization. All vertical stackeddisk<br />

designs inherently force a greater<br />

percentage of feed flow to the lower<br />

sections of the filter column, which<br />

are under higher hydrostatic pressure.<br />

The addition of the microporous<br />

membrane to Millistak+ HC filters<br />

helps to minimize this vertical pressure<br />

gradient, to utilize all available filter<br />

area more evenly and efficiently.<br />

Millistak+ HC Filters Application Guide 5

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