V. cholerae - Filippo Pacini

SEVEN PANDEMICS OF CHOLERA
Pandemic Year Comments
1 1817-23 Fisrt epidemic in the modern era
2 1829-51 Herman in Russia conceived the idea of giving
intravenous fluids
O´Shaugnessy and Latta infused saline
solutions to 15 patients; 5 survived
3 1852-9 Filippo Pacini coined the name V. cholerae
John Snow; the role of water, 1855
4 1863-79 Cholera was considered a moral problem
5 1881-96 Koch identified the Kommabacillen, 1883
6 1899-1926 Rogers reduced mortality with IV fluids
7 1961 .... Cash reported the succesful use of ORS
Greenough reported the utility of tetracycline in
severe cholera