V. cholerae - Filippo Pacini

Is the need to choose between options for cholera
control in Haiti still reasonable?
Improvements in provision of clean water and sanitation have not been
sufficient so far, in Haiti or elsewhere 1,2
Maintaining provision of clean water and sanitation can be difficult 3
The incidence of new cases may increase with the upcoming rainy
season 4
Endemic cholera may persist in Haiti at the end of the current epidemic,
with continued intermittent outbreaks generating more cases and deaths
than previously estimated 3,5
Averting even a modest number of cases will save lives 6
However, large scale cholera vaccination remains
difficult to implement due to limited vaccine
supply 1-6
1. Ryan ET. PLoS Negl Trop Dis 2011; 5(1): e1003;
2. Waldor MK et al. N Engl J Med 2010; 363:2279-2282;
3.Sack DA. Lancet 2011; 377:1214-1216
4.Andrews JP and Basu S. Lancet 2011; 377:1248-1255;
5. Chao DL et al. Proc Natl Acad Sci USA 2011;108:7081-7085;
6. Tuite AR et al. Ann Intern Med 2011;Mar 7 [Epub ahead of print]