V. cholerae - Filippo Pacini
V. cholerae - Filippo Pacini
V. cholerae - Filippo Pacini
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ROLE OF O BLOOD GROUP<br />
• Hospitalized patients with cholera were most likely to<br />
be of O blood group than controls<br />
• Volunteers carrying the O blood group presented<br />
more severe diarrhea when challenged with V.<br />
<strong>cholerae</strong> O1<br />
• In a study conducted in Lima; people with O blood<br />
group had almost 5 times higher risk to acquire<br />
severe cholera than people with other blood groups:<br />
( RR 4.8, 95%CI 2.2-10.7)<br />
• The underlying mechanism is not clearly understood
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