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penaeus monodon - Cochin University of Science and Technology

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PREFACE<br />

The spectacular progress scaled by aquaculture <strong>of</strong> penaeid shrimps<br />

has recently been put at risk by the dark clouds <strong>of</strong> disease manifestations.<br />

The etiological agents <strong>of</strong> many shrimp diseases in culture operations remain<br />

unknown. Diseases in shrimps can be caused by viral, bacterial or parasitic<br />

infestation, <strong>and</strong> also by other factors related to culture environment <strong>and</strong><br />

feed. One such feed associated disease is established to be <strong>of</strong> mycotoxin<br />

origin caused by fungal contamination <strong>of</strong> improperly stored feeds.<br />

Aflatoxin, a toxic contaminant produced by toxigenic fungi <strong>of</strong> the<br />

genus Aspergillus, during the processing <strong>and</strong> storage <strong>of</strong> feeds <strong>and</strong> feed<br />

ingredients, can cause abnormalities such as poor growth, physiological<br />

imbalances <strong>and</strong> histological changes that result in yield reduction <strong>and</strong><br />

pr<strong>of</strong>itability <strong>of</strong> shrimp culture. In humid tropical <strong>and</strong> semi-tropical<br />

environments, the stored feeds in shrimp culture facilities are vulnerable to<br />

production <strong>of</strong> aflatoxins due to the prevalance <strong>of</strong> favourable conditions for<br />

fungal growth.<br />

Very limited work on the potentiating factors <strong>of</strong> aflatoxicosis has<br />

been carried out. In the aquatic system, the animals are exposed to a wide<br />

variety <strong>of</strong> pathogens, pollutants, pesticides <strong>and</strong> stress factors. A diseased<br />

condition in an animal is the end result <strong>of</strong> not only one but the culmination<br />

<strong>of</strong> many factors. Hence the synergistic effects <strong>of</strong> two or many etiological<br />

agents can bring out toxicity in an animal.<br />

A colossal challenge presently is the detoxification <strong>of</strong> aflatoxin<br />

contaminated foods <strong>and</strong> feeds as they can cause severe liver abnormalities in<br />

the consumers. Hence, aflatoxin <strong>and</strong> major toxic metabolites enjoy<br />

considerable importance due to their effect on human <strong>and</strong> animals health.<br />

The present work is an attempt to elucidate the nutritional <strong>and</strong><br />

pathological changes associated with aflatoxicosis in P. <strong>monodon</strong>, <strong>and</strong> to

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