Download the full report (116 p.) - KCE
Download the full report (116 p.) - KCE
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70 Multislice CT in Coronary Heart Disease <strong>KCE</strong> Reports 82<br />
META-ANALYSIS OF DUAL-SOURCE 64-MSCT VS.<br />
CONVENTIONAL CORONARY ANGIOGRAPHY<br />
(≥50% STENOSIS) IN NATIVE CAD<br />
Summary Sensitivity<br />
Study | Sen [95% Conf. Iterval.] TP/(TP+FN)<br />
TN/(TN+FP)<br />
--------------------------------------------------------------------------------------<br />
------<br />
Alkadhi | 0,966 0,883 - 0,996 57/59 79/91<br />
Leber | 0,952 0,762 - 0,999 20/21 60/69<br />
Ropers | 0,976 0,874 - 0,999 41/42 47/58<br />
Weustink | 0,987 0,930 - 1,000 76/77 20/23<br />
--------------------------------------------------------------------------------------<br />
------<br />
Pooled Sen | 0,975 0,942 - 0,992<br />
--------------------------------------------------------------------------------------<br />
------<br />
Heterogeneity chi-squared = 1,08 (d.f.= 3) p = 0,783<br />
Inconsistency (I-square) = 0,0 %<br />
No. studies = 4.<br />
Filter OFF<br />
Add 1/2 to all cells of <strong>the</strong> studies with zero<br />
Summary Specificity<br />
Study | Spe [95% Conf. Iterval.] TP/(TP+FN)<br />
TN/(TN+FP)<br />
--------------------------------------------------------------------------------------<br />
------<br />
Alkadhi | 0,868 0,781 - 0,930 57/59 79/91<br />
Leber | 0,870 0,767 - 0,939 20/21 60/69<br />
Ropers | 0,810 0,686 - 0,901 41/42 47/58<br />
Weustink | 0,870 0,664 - 0,972 76/77 20/23<br />
--------------------------------------------------------------------------------------<br />
------<br />
Pooled Spe | 0,855 0,804 - 0,897<br />
--------------------------------------------------------------------------------------<br />
------<br />
Heterogeneity chi-squared = 1,16 (d.f.= 3) p = 0,764<br />
Inconsistency (I-square) = 0,0 %<br />
No. studies = 4.<br />
Filter OFF<br />
Add 1/2 to all cells of <strong>the</strong> studies with zero<br />
Summary Positive Likelihood Ratio (Random effects model)<br />
Study | LR+ [95% Conf. Iterval.] % Weight<br />
--------------------------------------------------------------------------------------<br />
------<br />
Alkadhi | 7,326 4,315 - 12,439 33,66<br />
Leber | 7,302 3,941 - 13,528 24,80<br />
Ropers | 5,147 3,017 - 8,780 33,07<br />
Weustink | 7,567 2,633 - 21,744 8,47<br />
--------------------------------------------------------------------------------------<br />
------<br />
(REM) pooled LR+ | 6,531 4,804 - 8,880<br />
--------------------------------------------------------------------------------------<br />
------<br />
Heterogeneity chi-squared = 1,15 (d.f.= 3) p = 0,764<br />
Inconsistency (I-square) = 0,0 %<br />
Estimate of between-study variance (Tau-squared) = 0,0000<br />
No. studies = 4.<br />
Filter OFF<br />
Add 1/2 to all cells of <strong>the</strong> studies with zero
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