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70 Multislice CT in Coronary Heart Disease KCE Reports 82 META-ANALYSIS OF DUAL-SOURCE 64-MSCT VS. CONVENTIONAL CORONARY ANGIOGRAPHY (≥50% STENOSIS) IN NATIVE CAD Summary Sensitivity Study | Sen [95% Conf. Iterval.] TP/(TP+FN) TN/(TN+FP) -------------------------------------------------------------------------------------- ------ Alkadhi | 0,966 0,883 - 0,996 57/59 79/91 Leber | 0,952 0,762 - 0,999 20/21 60/69 Ropers | 0,976 0,874 - 0,999 41/42 47/58 Weustink | 0,987 0,930 - 1,000 76/77 20/23 -------------------------------------------------------------------------------------- ------ Pooled Sen | 0,975 0,942 - 0,992 -------------------------------------------------------------------------------------- ------ Heterogeneity chi-squared = 1,08 (d.f.= 3) p = 0,783 Inconsistency (I-square) = 0,0 % No. studies = 4. Filter OFF Add 1/2 to all cells of the studies with zero Summary Specificity Study | Spe [95% Conf. Iterval.] TP/(TP+FN) TN/(TN+FP) -------------------------------------------------------------------------------------- ------ Alkadhi | 0,868 0,781 - 0,930 57/59 79/91 Leber | 0,870 0,767 - 0,939 20/21 60/69 Ropers | 0,810 0,686 - 0,901 41/42 47/58 Weustink | 0,870 0,664 - 0,972 76/77 20/23 -------------------------------------------------------------------------------------- ------ Pooled Spe | 0,855 0,804 - 0,897 -------------------------------------------------------------------------------------- ------ Heterogeneity chi-squared = 1,16 (d.f.= 3) p = 0,764 Inconsistency (I-square) = 0,0 % No. studies = 4. Filter OFF Add 1/2 to all cells of the studies with zero Summary Positive Likelihood Ratio (Random effects model) Study | LR+ [95% Conf. Iterval.] % Weight -------------------------------------------------------------------------------------- ------ Alkadhi | 7,326 4,315 - 12,439 33,66 Leber | 7,302 3,941 - 13,528 24,80 Ropers | 5,147 3,017 - 8,780 33,07 Weustink | 7,567 2,633 - 21,744 8,47 -------------------------------------------------------------------------------------- ------ (REM) pooled LR+ | 6,531 4,804 - 8,880 -------------------------------------------------------------------------------------- ------ Heterogeneity chi-squared = 1,15 (d.f.= 3) p = 0,764 Inconsistency (I-square) = 0,0 % Estimate of between-study variance (Tau-squared) = 0,0000 No. studies = 4. Filter OFF Add 1/2 to all cells of the studies with zero
KCE Reports 82 Multislice CT in Coronary Heart Disease 71 Summary Negative Likelihood Ratio (Random effects model) Study | LR- [95% Conf. Iterval.] % Weight -------------------------------------------------------------------------------------- ------ Alkadhi | 0,039 0,010 - 0,153 40,16 Leber | 0,055 0,008 - 0,372 20,39 Ropers | 0,029 0,004 - 0,205 19,86 Weustink | 0,015 0,002 - 0,105 19,59 -------------------------------------------------------------------------------------- ------ (REM) pooled LR- | 0,033 0,014 - 0,078 -------------------------------------------------------------------------------------- ------ Heterogeneity chi-squared = 0,99 (d.f.= 3) p = 0,803 Inconsistency (I-square) = 0,0 % Estimate of between-study variance (Tau-squared) = 0,0000 No. studies = 4. Filter OFF Add 1/2 to all cells of the studies with zero Summary Diagnostic Odds Ratio (Random effects model) Study | DOR [95% Conf. Iterval.] % Weight -------------------------------------------------------------------------------------- ------ Alkadhi | 187,63 40,416 - 871,02 40,00 Leber | 133,33 15,892 - 1118,7 20,84 Ropers | 175,18 21,678 - 1415,7 21,59 Weustink | 506,67 49,984 - 5135,9 17,57 -------------------------------------------------------------------------------------- ------ (REM) pooled DOR | 205,00 77,640 - 541,30 -------------------------------------------------------------------------------------- ------ Heterogeneity chi-squared = 0,79 (d.f.= 3) p = 0,852 Inconsistency (I-square) = 0,0 % Estimate of between-study variance (Tau-squared) = 0,0000 No. studies = 4. Filter OFF Add 1/2 to all cells of the studies with zero
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