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Download the full report (116 p.) - KCE

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86 Multislice CT in Coronary Heart Disease <strong>KCE</strong> Reports 82<br />

As far as <strong>the</strong> limited duration of <strong>the</strong> trial, and consequently <strong>the</strong> economic model, is<br />

concerned, we know from <strong>the</strong> clinical literature review that <strong>the</strong> prognosis of patients<br />

who present with atypical chest pain is generally good. Early intervention in patients<br />

with CAD but no documented ischemia diagnosed by MSCT angiography does not<br />

necessarily improve long-term outcomes in <strong>the</strong>se patients.<br />

The cost estimates in our base-case analysis only included direct health care costs.<br />

Indirect costs from productivity losses were not valued. In <strong>the</strong> RCT, more patients in<br />

<strong>the</strong> MSCT arm underwent revascularisation than in <strong>the</strong> standard of care arm.<br />

Revascularisation requires hospitalisation for, on average, 3 to 7 (PCI) or 13 to 18<br />

(CABG) days in Belgium.(https://tct.fgov.be/etct/anonymous?lang=nl; visited on April 10,<br />

2008) This would imply higher indirect costs associated with MSCT. As it was already<br />

clear from <strong>the</strong> direct cost calculation that MSCT is more expensive than standard of<br />

care, indirect costs would only add to <strong>the</strong> cost difference between MSCT and standard<br />

of care. This is a qualitative conclusion that can be drawn, without having to quantify <strong>the</strong><br />

precise impact on productivity.

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