V(D)J recombination and its defects
V(D)J recombination and its defects
V(D)J recombination and its defects
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Signal <strong>and</strong> coding joint formation in Artemis – patients<br />
signal<br />
joints<br />
coding<br />
joints<br />
signal joint assay coding joint assay<br />
pGG49 pGG51<br />
NV09F<br />
sj<br />
NV08F<br />
cj<br />
-Art +Art<br />
FM30 DG147<br />
FN1 control Artemis-1<br />
(deletion exon 10-12)<br />
NV09F<br />
NV08F<br />
cotransfection of RAG1, RAG2 <strong>and</strong> constructs<br />
with (+) or without (-) Artemis<br />
sj<br />
cj<br />
-Art +Art<br />
sj<br />
Artemis-2<br />
(exon 5 G47T)<br />
FM30 DG147<br />
cj<br />
-Art +Art
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