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V(D)J recombination and its defects

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Low numbers of T <strong>and</strong> B cells found in<br />

peripheral blood<br />

Patient Mean<br />

RAG-SCID<br />

Mean<br />

Artemis-SCID<br />

Control<br />

(x10 9 /l)<br />

B cells 0.01 0.001 0.001 0.2-1.6<br />

T cells 0.23 0.2 0.5 0.7-4.2<br />

NK cells 0.5 1.1 1.1 0.09-0.9

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