The differential diagnosis of hypernatraemia in children, with ...

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The Diagnosis of Salt Poisoning Leading to Hypematraemia in Children – September 2009 7. Recommendations for further research Case reports This guideline has confirmed that case reports are crucial to an appreciation of the range of causes for children presenting with hypernatraemia. As previously stated it is particularly difficult to undertake research into child abuse, and the best available evidence will continue to come from case reports. When the diagnosis is of non-accidental injury, parental consent for publication is very unlikely to be obtained. A recently published letter 306 highlights the difficulties in getting case reports of factitious illness in children published in UK journals without parental consent. The guideline group recommends that a mechanism for publishing such case reports be established to avoid publication bias whilst maintaining patient confidentiality. It is equally important to ensure publication of case reports concerning children in whom the diagnosis of salt poisoning was seriously considered but excluded. In particular publication is crucial where otherwise healthy young children were shown to have voluntarily ingested sufficient salt to render them hypernatraemic. It is recommended that case reports should be prepared with sufficient detail to allow peer review as undertaken for this guideline. Normal values for fractional excretion of sodium Although some studies have already been undertaken from which normal values for the fractional excretion of sodium can be extrapolated in children of different ages, the numbers of subjects are still small, and further studies are recommended in normal children. Further studies of fractional excretion of sodium in children presenting with other causes of hypernatraemia including hypernatraemic dehydration are recommended. Studies of sodium excretion rates Further research into sodium excretion rates in normal infants and children and those with other causes of hypernatraemia including hypernatraemic dehydration are recommended. 87
The Diagnosis of Salt Poisoning Leading to Hypematraemia in Children – September 2009 UK studies of hypernatraemia It is recommended that studies of the prevalence of hypernatraemia in the UK are undertaken. 88
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The Differential Diagnosis of Hyper
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The Diagnosis of Salt Poisoning Lea
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The differential diagnosis of hypernatraemia in children, with ...

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