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Locomotor Activity & Exploration Guide
Behavioral Test
Emergence Test
The Emergence Test is a free exploration
paradigm designed to reduce anxiety by
providing a safe enclosure within the open field
in order to assess approach or exploratory
behavior in rodents.
Briefly, the open field contained a white plastic
cylinder with an open end centrally located. The
subjects are placed into the cylinder and tested
for 10 to 15 minutes. The parameters commonly
evaluated in this task are the latency of
emergence from the cylinder, the total time spent
inside the cylinder, the time spent exploring the
cylinder and general locomotor activity.
Reasons for Choosing This Test
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Free exploration paradigm in reduced
anxiogenic environment
Easy to run
Sensitive for both mice and rats
Related Human Disease/Applications
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Drug Screening
Phenotyping
Parkinson’s Disease
Behavioral Test
Novel Object Test
The Novel Object Test is a free exploration
paradigm that provides animals the
opportunity to explore a novel object in a
familiar environmental context. Briefly, an
object is placed into the center of each open
field and the behavior of the animal (time spent
exploring the novel object and overall
locomotor activity) is registered during a
determined period of time.
Reasons for Choosing This Test
➤ Free exploration paradigm in a familiar environment
➤ Test maximizing approach/exploratory behavior
respect to avoidance/anxiety-related behavior
➤ Easy to run, even for inexperienced users
➤ Sensitive for both mice and rats
Related Human Disease/Applications
➤
➤
➤
Drug Screening
Phenotyping
Parkinson’s Disease
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