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Whipple's disease and Tropheryma whipplei

Whipple's disease and Tropheryma whipplei

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What specimens to send <strong>and</strong> how ?<br />

- Small-bowel biopsies (<strong>and</strong> other kinds biopsies) in<br />

10% formalin. Transport at room temperature. Samples<br />

fixed on formaline even several years before are also<br />

available for diagnosis.<br />

- Small-bowel biopsies (<strong>and</strong> other kinds biopsies),<br />

frozen at – 80°C. Transport in dry ice.<br />

-Saliva : 1 ml at least, frozen at –80°C. Transport in<br />

dry ice.<br />

-Stools frozen at –80°C. Transport in dry ice.<br />

-Urine frozen at –80°C. Transport in dry ice.<br />

-Blood sampled on one dry tube. Transport at room<br />

temperature.<br />

-Blood sampled on one EDTA tube. Transport at room<br />

temperature.<br />

-Blood sampled on one heparinized tube. Transport at<br />

room temperature.<br />

-In case of neurological signs or confirmed Whipple’s<br />

<strong>disease</strong> : 5 ml of LCR frozen at –80°C. Transport in dry ice.<br />

Address for sending the samples :<br />

Unité des Rickettsies, Faculté de Médecine<br />

27, Boulevard Jean Moulin<br />

13385 Marseille, France

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