Therapeutic Drug Monitoring in Oncology: The key to individualised ...
Therapeutic Drug Monitoring in Oncology: The key to individualised ...
Therapeutic Drug Monitoring in Oncology: The key to individualised ...
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Carboplat<strong>in</strong> dose for manageable<br />
haema<strong>to</strong>logical <strong>to</strong>xicity<br />
Dose(mg) = Target AUC x (GFR + 25)<br />
(Calvert Equation)<br />
Target AUC values;<br />
4 - 6 mg.ml/m<strong>in</strong> (pre-treated patients)<br />
6 - 8 mg.ml/m<strong>in</strong> (untreated patients)
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