2008 Pittcon Final Program - Pittcon Web Archives

EXHIBITOR NAME ROOM # DESCRIPTION
1:00 p.m.
“Acclaim HPLC Columns—The Solution to Your Separation Challenges”
Abstract: This seminar will discuss how Acclaim ® HPLC columns have been used for food safety,
environmental contaminants, consumer products testing, biofuel QC, and other separation challenges.
Included will be an overview of the Acclaim HPLC column line, including the specialty Acclaim
Surfactant, Organic Acid, Explosives, and Mixed-Mode columns.
2:00 p.m.
“Enhancing IC with the Addition of Mass Spectrometric Detection”
Abstract: Using Dionex’s unique chemical suppression interface, IC can be coupled directly to a mass
spectrometric detector. With the MSQ Plus system, Dionex is bringing laboratories a powerful tool
for environmental, chemical, and petrochemical applications. The IC/MS combination delivers new ion
analysis capabilities, including quantification of co-eluting ionic analytes, sensitive and specific
speciation, as well as selective determination of trace ions in high backgrounds.
3:00 p.m.
“Applications of Sampling and Analysis Approaches using Dionex Process Analytical IC/HPLC”
Abstract: This seminar will describe the capabilities of Dionex IC/HPLC systems to provide fullyautomated,
on-line analysis of your processes. Dionex has a solution for on-line IC/HPLC analysis of your
process no matter what the scale—lab, pilot plant, or full-scale manufacturing—and the experience to
back it up.
4:00 p.m.
“Multidimensional Chromatographic Analysis of Therapeutic Proteins on a Biocompatible LC System”
Abstract: This seminar will discuss a new biocompatible HPLC system for analysis of
biopharmaceutical proteins. The column compartment with two 2-position switching valves, in
combination with a dual gradient pump, readily supports multidimensional separations schemes. The
flexibility and robustness of the system will be demonstrated by the following examples: twodimensional
peptide mapping of monoclonal antibodies, stability testing of intact proteins, and ionexchange
purification and subsequent RP-HPLC-MS characterization of protein variants.
Tuesday, March 4, 2008
10:00 a.m.
“Analysis of Carbohydrates and Amino Acids using IC with Pulsed Amperometric Detection”
Abstract: The technique of HPAE-PAD has been used for more than 20 years for the determination of
carbohydrates and amino acids in many different matrices, such as foods, beverages and biological
systems. This approach is the “gold standard” by which all other methods and techniques are
measured. We will review the basics of HPAE-PAD and introduce new methods and technologies that
make this proven technique more accurate and reproducible over time, and across an expanded list of
samples and matrices.
11:00 a.m.
“Speeding Up and Revalidating Pharmaceutical HPLC Methods”
Abstract: A straight-forward approach to speeding up an existing LC method involves using a shorter
column to reduce run time, and a smaller particle size to counteract the resulting drop in resolution.
Once the user has selected a new fast LC column, the details of the optimized method are
automatically predicted by a software package. Usually, the next step is complete method revalidation,
a requirement in many laboratories. We present the systematic software-assisted speed-up of an
impurity profiling method in pharmaceutical quality control. Our solution allows laboratories to speedup
existing methods and revalidates them in less than 1 week.
12:00 p.m.
“Expanding Capabilities for Sample Preparation: Sample Pre-Treatment, Solvent Extraction and Post-
Extraction Clean-Up in a Single Step”
Abstract: This presentation will focus on the capabilities of the new ASE 350, including extraction of
acidic or alkaline matrices and the enhanced flexibility to run various sample sizes in the same run.
1:00 p.m.
“A New Dual Piston Integrated IC System Designed for Ease of Use”
Abstract: The ICS-900 is the new Dionex basic ion chromatography system. The ICS-900 is an
integrated instrument designed for very good chromatographic performance due to its dual piston,
serial pump design. This design makes it possible to perform high quality IC on 2-mm diameter
columns, without head pressure on the pump. This presentation will focus on the chromatographic
performance of the system using 2-mm columns for the analysis of both anions and cations in water.
The advantages of 2-mm columns, including four-fold reductions in eluent and regenerant usage, will
be discussed. We will show the key design features of the new instrument, highlight the software tools
designed to simplify operation of the ICS-900, and briefly review the DVD-based tools for installation,
maintenance and troubleshooting.