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Full Clinical Guidelines - Community First Health Plans.

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Risk Factors for Osteoporosis Fractures<br />

www.nof.org<br />

Non-modifiable:<br />

• Personal history of fracture as an adult<br />

• History of fracture in first-degree relative<br />

• Caucasian/Asian race<br />

• Advanced age<br />

• Female sex<br />

• Dementia<br />

• Poor health/frailty<br />

Potentially Modifiable:<br />

• Current cigarette smoking<br />

• Low body weight (1 year)<br />

• Low calcium intake (lifelong)<br />

• Alcoholism<br />

• Impaired eyesight despite correction<br />

• Recurrent falls<br />

• Inadequate physical activity<br />

• Poor health/frailty<br />

• Use of corticosteroid therapy for >3 months<br />

The four items in boldface type are key factors in determining risk of hip fracture independent of BMD.<br />

Who should be tested?<br />

Your healthcare provider may recommend a bone mineral density (BMD) test if you are:<br />

• A postmenopausal woman under age 65 with one or more risk factors for osteoporosis<br />

• A man age 50-70 with one or more risk factors for osteoporosis<br />

• A woman age 65 or older, even without any risk factors<br />

• A man age 70 or older, even without any risk factors<br />

• A woman or man after age 50 who has broken a bone<br />

• A woman going through menopause with certain risk factors<br />

• A postmenopausal woman who has stopped taking estrogen therapy (ET) or hormone therapy (HT)<br />

Some other reasons your healthcare provider may recommend a BMD test:<br />

• Long-term use of certain medications including steroids (for example, prednisone and cortisone), some anti-seizure<br />

medications, Depo-Provera® and aromatase inhibitors (for example, anastrozole, brand name Arimidex®)<br />

• A man receiving certain treatments for prostate cancer<br />

• A woman receiving certain treatments for breast cancer<br />

• Overactive thyroid gland (hyperthyroidism) or taking high doses of thyroid hormone medication<br />

• Overactive parathyroid gland (hyperparathyroidism)<br />

• X-ray of the spine showing a fracture or bone loss<br />

• Back pain with a possible fracture<br />

• Significant loss of height<br />

• Loss of sex hormones at an early age, including early menopause<br />

• Having a disease or condition that can cause bone loss (such as rheumatoid arthritis or anorexia nervosa)<br />

National Osteoporosis Foundation. Physician’s guide to prevention and treatment of osteoporosis. Washington (DC): National Osteoporosis Foundation; 2008,<br />

p.13<br />

Who should be treated?<br />

Postmenopausal women and men age 50 and older presenting with the following should be considered for treatment:<br />

• A hip or vertebral (clinical or morphometric) fracture<br />

• T-score ≤ -2.5 at the femoral neck or spine after appropriate evaluation to exclude secondary causes<br />

• Low bone mass (T-score between -1.0 and -2.5 at the femoral neck or spine) and a 10-year probability of a hip fracture ≥ 3%<br />

or a 10-year probability of a major osteoporosis-related fracture ≥ 20% based on the US-adapted WHO algorithm<br />

14.2 Recommendations from National Osteoporosis Foundation<br />

H EALTH PLANS<br />

www.cfhp.com<br />

109

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