Printable Test Catalog - OU Medicine

CPT: 82542
[CHOLIN] Serum Cholinesterase
SPECIMEN REQUIRED: Refrigerated serum
TUBE OR CONTAINER: Red or Gold
SPECIAL HANDLING: Separate serum from red cells immediately
after clotting (30 minutes)
SPECIMEN VOLUME: 0.5 mL
MINIMUM VOLUME: 0.2 mL
TEST AVAILABILITY: Daily
TURNAROUND TIME: 2-3 days
REFERENCE RANGE: 1900 - 3800 IU/L
METHODOLOGY: Spectrophotometry (Ellman) - kinetic
CLINICAL USE: Evaluate pre-operative patients for
succinylcholine anesthetic sensitivity, genetic
or secondary to insecticide exposure
CPT: 82480
[CHOLINH] CHOLIN INHIBITION BY DIBUCAINE
SPECIMEN REQUIRED: Refrigerated plasma AND whole blood
TUBE OR CONTAINER: Lavender (EDTA)
SPECIAL HANDLING: Collect 2 lavender tubes; centrifuge and
separate 1 tube only; submit with remaining
whole blood tube. Do not collect within 24
hours of administration of muscle relaxants
SPECIMEN VOLUME: 2 mL (plasma)
5 mL (whole blood)
MINIMUM VOLUME: 0.1 mL (plasma)
1 mL (whole blood)
TEST INCLUDES: Dibucaine number, plasma cholinesterase, and RBC
cholinesterase
TEST AVAILABILITY: Daily
TURNAROUND TIME: 2-3 days
REFERENCE RANGE: See individual tests
METHODOLOGY: Cholinesterase by spectrophotometry (Ellman) with
dibucaine inhibition
CLINICAL USE: Assess the presence of homozygous or heterozygous
"atypical" cholinesterase variant, in patients
who have low result of serum or plasma
cholinesterase assay, and may be at risk of apnea
when given succinylcholine muscle relaxant
CPT: 82480; 82482; 82638
[CHOLINR] RBC Cholinesterase
SPECIMEN REQUIRED: Refrigerated whole blood
TUBE OR CONTIAINER: Lavender (EDTA)
SPECIAL HANDLING: Refrigerate entire sample; do not separate.
Stable in whole blood for at least 48 hours
when refrigerated at 2 C to 8 C
SPECIMEN VOLUME: 5 mL