Joseph Breese - Sabin Vaccine Institute

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Influenza vaccines: types Live attenuated vaccines • Medimmune; Russia; others in development • Delivered by nasal spray or dropper o (0.2cc divided into each nostril) • Nonpregnant, healthy individuals ages 2-49 years o Includes most HCWs o Excludes children 2-4 yrs with asthma or wheezing in last year • Potential advantages: o Ease of use o No needles o Induction of broader immunity (cell-mediated); increased heterosubtypic protection o Potentially longer-lasting immunity o Superior effectiveness in children • Limited availability
Seasonal Influenza <strong>Vaccine</strong>s VACCINE EFFECTIVENESS
Page 1 and 2: Overview of seasonal Influenza Vacc
Page 3 and 4: Seasonal Influenza Vaccines INFLUEN
Page 5 and 6: Clinical trials of inactivated vacc
Page 7 and 8: Influenza Vaccines - overview • T
Page 9 and 10: Influenza vaccines: types “Standa
Page 11: Influenza vaccines: types High-dose
Page 15 and 16: Influenza Vaccine efficacy if IIV i
Page 17 and 18: Vaccine effectiveness: special popu
Page 19 and 20: Indirect effects of influenza vacci
Page 21 and 22: Estimates number of medically-atten
Page 23 and 24: Influenza vaccines have been part o
Page 25 and 26: Seasonal Influenza Vaccines CHALLEN
Page 27 and 28: Gaps • Most partners need educati
Page 29: THANK YOU

Joseph Breese - Sabin Vaccine Institute

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