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Joseph Breese - Sabin Vaccine Institute

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Influenza <strong>Vaccine</strong> efficacy if IIV in adults:<br />

meta-analyses<br />

Study<br />

Demicheli, et al<br />

(2000)<br />

Demicheli, et al<br />

(2009)<br />

Osterholm, et al<br />

(2012)<br />

No. studies<br />

reviewed<br />

Population Outcome VE<br />

10 Adults Lab-confirmed<br />

influenza<br />

38 Adults Lab-confirmed<br />

influenza<br />

8 18-65 y Lab-confirmed<br />

influenza<br />

68 (49-79)<br />

80 (56 – 91) [good match]<br />

50 (27-65) [poor match]<br />

59 (51-67)

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