Joseph Breese - Sabin Vaccine Institute
Joseph Breese - Sabin Vaccine Institute
Joseph Breese - Sabin Vaccine Institute
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Influenza <strong>Vaccine</strong>s - overview<br />
• Trivalent (H1N1, H3N2, B)<br />
– Quadrivalent fomulations now or soon licensed that<br />
include 2 B virus antigens<br />
• Annual vaccination required for optimal protection<br />
– Antigenic changes in circulating strains<br />
– <strong>Vaccine</strong>-induced antibodies wane over time<br />
• Influenza vaccine programs:<br />
– Conducted as seasonal campaigns (before local disease<br />
peaks)<br />
– (Mostly) target persons at high-risk of severe outcomes<br />
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