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Joseph Breese - Sabin Vaccine Institute

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Influenza vaccines: types<br />

“Standard” Inactivated vaccines<br />

• Many manufacturers<br />

• Intramuscular injection<br />

• 0.5cc per dose<br />

• often decreased to 0.25cc for children 6-35 months<br />

• Contains 15 µg hemagglutinin of each virus strain per 0.5cc dose<br />

• 6 months of age or older – products vary<br />

• Protection primarily mediated by humoral immunity against the<br />

hemagglutinin protein<br />

• Protection correlated with serum antibody levels postvaccination

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