Pre-Eclampsia
Pre-Eclampsia
Pre-Eclampsia
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Sectio preterm<br />
Difference in local anaesthetic requirements:<br />
• à term ( 38-42 w ) vs preterm ( 28-35 w )<br />
• CSE met hyperbare marcaine: 2.25 ml (11.25<br />
mgr)<br />
• <strong>Pre</strong>term: onvoldoende bij 21/25 parturienten<br />
• Onset bij preterme groep trager<br />
• À term: voldoende hoog block bij alle ptn T4<br />
• Minder hypotensie<br />
Compression of vena cava<br />
Increased sensitivity to local anesthetic<br />
Dr. Marc Coppens<br />
Remifentanil<br />
• µ opioid receptor antagonist<br />
• High potency !!!<br />
• Low onset time<br />
• Rapidly hydrolyzed<br />
• Small volume of distibution<br />
• High clearance<br />
• Does not rely on pseudocholinesterase<br />
Dr. Marc Coppens<br />
15
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