Pre-Eclampsia
Pre-Eclampsia
Pre-Eclampsia
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Magnesium<br />
• Vasodilator activity<br />
– Direct and indirect effects<br />
– Sympathetic block<br />
• Direct smooth muscle relaxation<br />
in uterus<br />
– Inhibition of catecholamine release<br />
Control of hypertension at laryngoscopy and intubation<br />
Cave hypotension with regional anesthesia<br />
Cave postpartum hemorrhage<br />
Sense of warmth at the tongue with rapid bolus<br />
Dr. Marc Coppens<br />
Management of imminent eclampsia or<br />
eclampsia<br />
• Airway, Breahting, Circulation<br />
• Left lateral position, maintain airway<br />
• Administer oxygen, check for aspiration or<br />
pulmonary oedema<br />
• MgSO 4 = therapy of choice<br />
• Vast majority of initial seizures are self-limiting<br />
• Diazepam, phenytoin not as first-line treatment<br />
Dr. Marc Coppens<br />
7
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