View conference programme - The British Society for Rheumatology

OP54 OX40L, BUT NOT OX40, IS ASSOCIATED WITH SYSTEMIC LUPUS ERYTHEMATOSUS.
DS Cunninghame Graham, TJ Vyse. Rheumatology Section, Imperial College, Hammersmith Campus,
Eric Bywaters Centre, London, United Kingdom
OP55 HETEROGENEITY AMONGST PATIENTS WITH CHRONIC INFANTILE NEUROLOGICAL CUTA-
NEOUS AND ARTICULAR (CINCA) SYNDROME.
E Aganna, 1 JE Davidson, 2 G Cleary, 2 JA Sills, 2 A Bybee, 3 E Drewe, 4 GA Hitman, 1 P Woo, 5 PN Hawkins, 3 MF
McDermott. 1 1 Centre for Diabetes & Metabolic Medicine, Queen Mary School of Medicine and Dentistry,
London, United Kingdom; 2 Rheumatology, Royal Liverpool Children’s Hospital, Alder Hey, Liverpool,
United Kingdom; 3 Centre for Amyloidosis, Royal Free Hospital, London, United Kingdom; 4 Molecular and
Clinical Immunology, Queen’s Medical Centre, Nottingham, United Kingdom; 5 Rheumatology, Child
Health, University College, London, United Kingdom
OP56 HIGH RESOLUTION LINKAGE DISEQUILIBRIUM MAPPING IDENTIFIES ASSOCIATION TO SINGLE
NUCLEOTIDE POLYMORPHISM MARKERS MAPPING TO A REGION OF LINKAGE ON CHROMOSOME
17Q22 WITH RHEUMATOID ARTHRITIS.
A Barton 1 , D Ward 1 , S Eyre 1 , A Hinks 1 , A Silman 1 , E Culbert 2 , S John 3 , J Worthington 1 . 1
ARC-EU, University
of Manchester, Manchester, United Kingdom; 2 Astra-Zeneca Pharmceuticals Ltd, Alderley Park,
Macclesfield, Cheshire, United Kingdom; 3 CIGMR, University of Manchester, Manchester, United Kingdom
OP57 THE BXSB INTERVAL ON CHROMOSOME 13 (BXS6) IS NECESSARY AND SUFFICIENT FOR HIGH
TITRE GP70 AUTOANTIGEN SYNTHESIS AND CONCOMITANT AUTOANTIBODY PRODUCTION.
JM Rankin 1 , MEK Haywood 1 , A McDermott 1 , S Izui 2 , B Morley 1 . 1
Rheumatology Section,
The Eric Bywaters Centre, Imperial College, London, United Kingdom; 2 Department of Pathology,
C.M.U, Geneva, Switzerland
OP58 MICROARRAY ANALYSIS OF CHROMOSOME 1 CONGENIC BXSB MICE REVEALS
NOVEL LUPUS-SUSCEPTIBILITY GENE CANDIDATES.
MEK Haywood, J Rose, G Fu, MJ Walport, BJ Morley. Rheumatology Section, Eric Bywaters Centre,
Imperial College, London, United Kingdom
Young Investigator Award Winner
OP60 THE IL1 GENE CLUSTER IS A MAJOR LOCUS DETERMINING SUSCEPTIBILITY TO
ANKYLOSING SPONDYLITIS.
AE Timms 1 , AM Crane 1 , A-M Sims 1 , H Cordell 2 , L Bradbury 1 , O Beynon 1 , GR Duff 5 , LR Cardon 4 , A Calin 3 ,
P Wordsworth 1 , MA Brown 1 . 1
Institute of Musculoskeletal Sciences, The Botnar Research Centre, Oxford,
United Kingdom; 2 Cambridge Institute of Medical Research, Addenbrookes Hospital, Cambridge, United
Kingdom; 3 Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom; 4 Wellcome Trust
Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; 5 Division of Genomic
Medicine, University of Sheffield, Sheffield, United Kingdom
CONNECTIVE TISSUE DISEASE (OP61 – OP68) Sidlaw
OP61 UPREGULATION OF THE MONOCYTE CHEMOATTRACTANT PROTEIN -1 LIGAND-RECEPTOR
AXIS IN EARLY STAGE DIFFUSE CUTANEOUS SCLERODERMA.
MT Carulli, V Ong, M Ponticos, X Shiwen, L Shand, DJ Abraham, CM Black, CP Denton. Centre for
Rheumatology, Royal Free Hospital, London, United Kingdom
OP62 A LONGITUDINAL ANALYSIS OF SKIN SCLEROSIS AND ORGAN-BASED ENDPOINTS
IN A COHORT OF EARLY DIFFUSE CUTANEOUS SYSTEMIC SCLEROSIS.
LM Shand, M Hosseini, CM Black, CP Denton. Centre for Rheumatology, Royal Free and University
College Medical School, London, United Kingdom
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