View conference programme - The British Society for Rheumatology

256 DOES ANTINUCLEAR ANTIBODY ELISA MISS SIGNIFICANT CONNECTIVE TISSUE DISEASE ?
AYN Lim, G Maguire, G Wood, DS Kumararatne, JSH Gaston. 1 Department of Rheumatology,
Addenbrooke’s Hospital, Cambridge, Cambs, United Kingdom; 2 Department of Clinical Immunology,
Addenbrooke’s Hospital, Cambridge, Cambs, United Kingdom; 3 Department of Clinical Immunology,
Addenbrooke’s Hospital, Cambridge, Cambs, United Kingdom; 4 Department of Clinical Immunology,
Addenbrooke’s Hospital, Cambridge, Cambs, United Kingdom; 5 Department of Rheumatology,
Addenbrooke’s Hospital, Cambridge, Cambs, United Kingdom
257 DOUBLE BLIND, CROSSOVER, RANDOMISED TRIAL COMPARING LOW MOLECULAR WEIGHT
HEPARIN VERSUS PLACEBO IN THE TREATMENT OF CHRONIC HEADACHE IN PATIENTS WITH
ANTIPHOSPHOLIPID ANTIBODIES.
G Sanna 1 , MJ Cuadrado 2 , M Sharief 3 , MA Khamashta 4 , GRV Hughes 5 . 1
Rheumatology, Homerton
University Hospital, London, England, United Kingdom; 2 Lupus Rearch Unit, St. Thomas’ Hospital,
London, England, United Kingdom; 3 Neurology, St. Thomas’ Hospital, London, England, United Kingdom;
4
Lupus Research Unit, St. Thomas’ Hospital, London, England, United Kingdom; 5 Lupus Research Unit,
St. Thomas’ Hospital, London, England, United Kingdom
258 THE RELATIONSHIP BETWEEN DISEASE ACTIVITY AND QUALITY OF LIFE IN SYSTEMIC
LUPUS ERYTHEMATOSUS.
S Khanna 1 , H Pal 2 , RM Pandey 3 , R Handa 4 . 1
All India Institute of Medical Sciences, New Delhi, India;
2
Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India; 3 Department of
Biostatistics, All India Institute of Medical Sciences, New Delhi, India; 4 Department of Medicine, All India
Institute of Medical Sciences, New Delhi, India
259 PREVALENCE OF ANTITHYROID ANTIBODIES IN ANTIPHOSPHOLIPID SYNDROME.
P Harrison 1 , GT Swana 2 , MR Swana 3 , ML Bertolaccini 1 , MA Khamashta 1 , DP D’Cruz 1 , GRV Hughes 1 . 1 Lupus
Research Unit, The Rayne Institute, London, United Kingdom; 2 Immunology Department, St.Thomas’
Hospital, London, United Kingdom; 3 Immunology Department, University College London Hospital,
London, United Kingdom
260 ATYPICAL CO-LOCALISATION OF CD45 AND LYN TO LIPID RAFT SIGNALLING DOMAINS
CORRELATES WITH B-LYMPHOCYTE HYPER RESPONSIVENESS IN PATIENTS WITH LUPUS.
F Flores-Borja 1 , PS Kabouridis 1 , E Jury 2 , D Isenberg 2 , RA Mageed 1 . 1
Bone and Joint Research Unit,
St Bartholomew’s and The Royal London, Queen Mary School of Medicine, London, United Kingdom;
2
Centre for Rheumatology, University College London, London, United Kingdom
261 A SINGLE MUTATION OF AN ARGININE RESIDUE ALTERS THE BINDING AFFINITY OF A HUMAN
MONOCLONAL ANTIBODY TO DIFFERENT ANTIGENS.
N Lambrianides 1,2 , A Rahman 1,2 , L Mason 2 , D Latchman 1 , D Isenberg 2 . 1
Medical Molecular Biology Unit,
Institute of Child Health, University College London, London, United Kingdom; 2 Centre for
Rheumatology, University College London, London, United Kingdom
262 ANTIBODIES AGAINST OXIDISED THE COMPLEX LOW DENSITY LIPOPROTEIN-BETA - 2 -
G LYCOPROTEIN-I MAY HAVE A PRO- ATHEROGENIC ROLE IN PRIMARY ANTIPHOSPHOLIPID SYNDROME.
PRJ Ames 1 , J Delgado-Alves 2 , D Lopez 3 , L Lopez 3 , E Matsuura 4 , A Margarita 5 , L Iannaccone 5 ,
V Brancaccio 5 . 1
Academic Department of Rheumatology, Leeds General Infirmary, Leeds, United
Kingdom; 2 Department of Internal Medicine, Curry Cabral Hospital, Lisbon, Portugal; 3 Science and
Research, Corgenix Ltd, Denver, CO, United States; 4 Department of Biochemistry, Okayama School of
Medicine, Okayama, Japan; 5 Angiohaemostasis Unit, Ospedale A. Cardarelli, Naples, Italy
263 STABLE TRANSFECTION OF CHO CELLS TO EXPRESS WHOLE HUMAN IgG ANTIPHOSPHOLIPID
ANTIBODIES.
N Lambrianides 1,2 , I Giles 1,2 , D Latchman 1 , D Isenberg 2 , A Rahman 1,2 . 1
Medical Molecular Biology Unit,
Institute of Child Health, University College London, London, United Kingdom; 2 Centre for
Rheumatology, University College London, London, United Kingdom
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