View conference programme - The British Society for Rheumatology
View conference programme - The British Society for Rheumatology
View conference programme - The British Society for Rheumatology
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71 METHOTREXATE MONITORING: A COUNTRYWIDE ANALYSIS OF MONITORING POLICIES AMONG<br />
RHEUMATOLOGISTS AND DERMATOLOGISTS IN THE REPUBLIC OF IRELAND.<br />
JG Ryan 1 , J Barry 2 , J Bourke 2 , M Phelan 1 . 1<br />
Departments of <strong>Rheumatology</strong>, South Infirmary- Victoria<br />
Hospital, Cork, Ireland; 2 Dermatology, South Infirmary- Victoria Hospital, Cork, Ireland<br />
CARTILAGE BIOLOGY (72 – 76)<br />
72 A NOVEL INDUCIBLE NITRIC OXIDE SYNTHASE (iNOS) INHIBITOR INFLUENCES AGGRECAN<br />
mRNA LEVELS IN OSTEOARTHRITIC (OA) CHONDROCYTES.<br />
JE Johnston 1 , SJ Millward-Sadler 1 , N Boughton-Smith 2 , G Nuki 1 . 1<br />
Osteoarthritis Research Lab, Edinburgh<br />
University, Edinburgh, Scotland, United Kingdom; 2 Research And Development, AstraZeneca,<br />
Loughborough, Leicestershire, United Kingdom<br />
73 EFFECTS OF MECHANICAL STIMULATION ON MAP KINASES IN NORMAL AND OSTEOARTHRITIC<br />
HUMAN ARTICULAR CHONDROCYTES.<br />
Y Zhou, SJ Millward-Sadler, NS Khan, DM Salter, G Nuki. Osteoarticular Research Group, Medical<br />
College, University of Edinburgh, Edinburgh EH8 9AG, Scotland, United Kingdom<br />
74 INTEGRIN DEPENDENT UP-REGULATION OF PROTEOGLYCAN SYNTHESIS IN CULTURED<br />
NORMAL HUMAN ARTICULAR CHONDROCYTES FOLLOWING MECHANICAL STIMULATION IS LOST<br />
IN CHONDROCYTES FROM PATIENTS WITH OSTEOARTHRITIS AND RHEUMATOID ARTHRITIS.<br />
M Maruo Holledge, SJ Millward-Sadler, NS Khan, DM Salter, G Nuki. Osteoarticular Research Group,<br />
Medical College, University of Edinburgh, Edinburgh EH8 9AG, Scotland, United Kingdom<br />
75 CHANGE IN SERUM CARTILAGE OLIGOMERIC MATRIX PROTEIN (COMP) AFTER TOTAL<br />
KNEE REPLACEMENT FOR OSTEOARTHRITIS (OA).<br />
M Sharif 1 , JR Kirwan 2 , R Granell 2 , S Clarke 2 . 1<br />
Department of Anatomy, University of Bristol, Bristol,<br />
United Kingdom; 2 Academic <strong>Rheumatology</strong> Unit, Bristol Royal Infirmary, Bristol, United Kingdom<br />
76 INCREASED EXPRESSION OF CATABOLIC CYTOKINES AND THEIR RECEPTORS IN EARLY<br />
EQUINE ARTICULAR CARTILAGE DAMAGE.<br />
MJ Trickett, M Sharif, MJ Perry, CJ Fuller. Anatomy, University of Bristol, Bristol, United Kingdom<br />
BONE BIOLOGY (77 – 79)<br />
77 TARTRATE-RESISTANT ACID PHOSPHATASE: A POTENTIAL TARGET FOR THERAPEUTIC GOLD.<br />
AR Hayman 1 , TM Cox 2 . 1<br />
Clinical Veterinary Science, University of Bristol, Bristol, BS40 5DU, United<br />
Kingdom; 2 Medicine, Addenbrooke’s Hospital, University of Cambridge, Cambridge, CB2 2QQ, United<br />
Kingdom<br />
78 LIGAMENTS AND BONE JOIN AT SACRAL AND ILIAC ENTHESES BY DISCONTINUOUS<br />
ATTACHMENT ZONES DEFINED BY TENASCIN AND TYPE VI COLLAGEN.<br />
L Fairbairn, SJ Millward-Sadler, DM Salter, DL Gardner. Pathology, University of Edinburgh, Edinburgh,<br />
United Kingdom<br />
79 COMPARATIVE ANALYSIS OF STRUCTURES WITHIN THE OSTEOARTHRITIC KNEE JOINTS REVEALS<br />
MESENCHYMAL PROGENITOR CELL (MPC) ACTIVITY IN ALL TISSUES, IMPLICATIONS FOR THE ROLE<br />
OF THE MICROENVIRONMENT IN REPAIR.<br />
A English 1 , EA Jones 1 , K Henshaw 1 , D Corscadden 1 , J Holdsworth 2 , T Chapman 3 , R Reece 1 , P Emery 1 ,<br />
D McGonagle 2 . 1<br />
<strong>Rheumatology</strong> and Rehabilitation Research Unit, University of Leeds, Leeds, Yorkshire,<br />
United Kingdom; 2 <strong>Rheumatology</strong> Department, Calderdale General Hospital, Halifax, Yorkshire, United<br />
Kingdom; 3 Orthopaedic Department, Calderdale General Hospital, Halifax, Yorkshire, United Kingdom<br />
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