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What Really Causes Alzheimer's Disease - Soil and Health Library

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mutations involved in promoting the development of Alzheimer’s<br />

disease duplicate some of aluminum’s deleterious impacts<br />

on the brain <strong>and</strong>, in so doing, encourage at least one of the<br />

following: the growth of neuritic plaques or neurofibrillary tangles,<br />

excessive free radical formation, <strong>and</strong>/or higher neural<br />

oxidative stress. Consequently, unfortunate individuals carrying<br />

any one of the genetic variants are much more likely to<br />

develop Alzheimer’s disease, even if they are not exposed to the<br />

aluminum excess, or to the vitamin <strong>and</strong> mineral deficiencies,<br />

that are normally associated with its etiology.<br />

Alzheimer’s disease incidence appears to be rising faster than<br />

the population is aging. Obviously, such an increase cannot<br />

be due to any genetic cause. One does not have “epidemics” of<br />

genetic diseases, simply because the human genome does not<br />

change rapidly enough to trigger them. If, as the evidence<br />

strongly hints, Alzheimer’s disease is becoming generally more<br />

common, it must be because the “harmful environments” that<br />

trigger it are now more widespread. There is no doubt that,<br />

globally, soils <strong>and</strong> water are becoming more acidic <strong>and</strong>, consequently,<br />

aluminum more soluble. Throughout the 20 th <strong>and</strong> early<br />

21 st centuries, as a result of exp<strong>and</strong>ing fossil fuel consumption,<br />

ever increasing quantities of sulphur <strong>and</strong> nitrogen were<br />

emitted into the atmosphere. Here they were converted into<br />

sulphuric <strong>and</strong> nitric acids, elevating the acidity of subsequent<br />

precipitation. 11 Such acid rain has caused extensive damage<br />

to the environment at local, regional, <strong>and</strong> even global scales.<br />

It has been particularly problematic in northern <strong>and</strong> central<br />

Europe, eastern North America, <strong>and</strong> eastern China where it<br />

has been associated with many health costs. 12 Simultaneously,<br />

commercial fertilizers have been used with increasing frequency.<br />

These consist predominantly of nitrogen, phosphorus,<br />

<strong>and</strong> potassium. As a consequence of heavy crop yields, agricultural<br />

soils have been depleted of several minerals that are<br />

important for human health, including calcium <strong>and</strong> magnesium.<br />

ix

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